Published in Nat Biotechnol on October 16, 2011
The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine. Hum Genet (2014) 6.69
Key role of CRF in the skin stress response system. Endocr Rev (2013) 1.77
Whole-genome sequencing of six Mauritian Cynomolgus macaques (Macaca fascicularis) reveals a genome-wide pattern of polymorphisms under extreme population bottleneck. Genome Biol Evol (2015) 1.53
Paired-end sequencing of Fosmid libraries by Illumina. Genome Res (2012) 1.52
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. Nat Genet (2014) 1.49
Examining the species-specificity of rhesus macaque cytomegalovirus (RhCMV) in cynomolgus macaques. PLoS One (2015) 1.43
New insights into samango monkey speciation in South Africa. PLoS One (2015) 1.40
Identification of microRNAs in Macaca fascicularis (Cynomolgus Monkey) by Homology Search and Experimental Validation by Small RNA-Seq and RT-qPCR Using Kidney Cortex Tissues. PLoS One (2015) 1.38
Challenges and approaches for the development of safer immunomodulatory biologics. Nat Rev Drug Discov (2013) 1.35
Comparative primate genomics: emerging patterns of genome content and dynamics. Nat Rev Genet (2014) 1.23
A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Biol Direct (2014) 1.20
The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics. Nucleic Acids Res (2012) 1.13
Whole-genome sequencing and analysis of the Malaysian cynomolgus macaque (Macaca fascicularis) genome. Genome Biol (2012) 1.12
Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors. Mol Ther (2015) 1.02
Haplessly hoping: macaque major histocompatibility complex made easy. ILAR J (2013) 1.02
RhesusBase: a knowledgebase for the monkey research community. Nucleic Acids Res (2012) 1.02
Primate genome architecture influences structural variation mechanisms and functional consequences. Proc Natl Acad Sci U S A (2013) 0.97
Modeling tuberculosis in nonhuman primates. Cold Spring Harb Perspect Med (2014) 0.95
Adventures in data citation: sorghum genome data exemplifies the new gold standard. BMC Res Notes (2012) 0.93
Single-nucleotide polymorphisms reveal patterns of allele sharing across the species boundary between rhesus (Macaca mulatta) and cynomolgus (M. fascicularis) macaques. Am J Primatol (2012) 0.92
Improving genome assemblies and annotations for nonhuman primates. ILAR J (2013) 0.91
Data management strategies for multinational large-scale systems biology projects. Brief Bioinform (2012) 0.91
Large-scale transcriptome sequencing and gene analyses in the crab-eating macaque (Macaca fascicularis) for biomedical research. BMC Genomics (2012) 0.89
Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity. Nat Commun (2016) 0.87
Selection of new appropriate reference genes for RT-qPCR analysis via transcriptome sequencing of cynomolgus monkeys (Macaca fascicularis). PLoS One (2013) 0.87
Whole genome sequencing of SIV-infected macaques identifies candidate loci that may contribute to host control of virus replication. Genome Biol (2014) 0.86
Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques. J Immunol (2014) 0.86
Old world monkeys and new age science: the evolution of nonhuman primate systems virology. ILAR J (2013) 0.85
Assessment and improvement of Indian-origin rhesus macaque and Mauritian-origin cynomolgus macaque genome annotations using deep transcriptome sequencing data. J Med Primatol (2014) 0.84
Whole-genome sequencing of tibetan macaque (Macaca Thibetana) provides new insight into the macaque evolutionary history. Mol Biol Evol (2014) 0.83
Genetic substructure in cynomolgus macaques (Macaca fascicularis) on the island of Mauritius. BMC Genomics (2014) 0.83
Emergence, Retention and Selection: A Trilogy of Origination for Functional De Novo Proteins from Ancestral LncRNAs in Primates. PLoS Genet (2015) 0.82
Frequent loss and alteration of the MOXD2 gene in catarrhines and whales: a possible connection with the evolution of olfaction. PLoS One (2014) 0.80
Mitogenomic phylogeny of the common long-tailed macaque (Macaca fascicularis fascicularis). BMC Genomics (2015) 0.80
Selectively Constrained RNA Editing Regulation Crosstalks with piRNA Biogenesis in Primates. Mol Biol Evol (2015) 0.80
Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation. Genome Res (2015) 0.79
Binding of HSV-1 glycoprotein K (gK) to signal peptide peptidase (SPP) is required for virus infectivity. PLoS One (2014) 0.79
Finding the factors of reduced genetic diversity on X chromosomes of Macaca fascicularis: male-driven evolution, demography, and natural selection. Genetics (2013) 0.79
In transition: primate genomics at a time of rapid change. ILAR J (2013) 0.79
Experimental primates and non-human primate (NHP) models of human diseases in China: current status and progress. Dongwuxue Yanjiu (2014) 0.79
Plasmodium cynomolgi infections in rhesus macaques display clinical and parasitological features pertinent to modelling vivax malaria pathology and relapse infections. Malar J (2016) 0.79
Identification of Mamu-DPA1, Mamu-DQA1, and Mamu-DRA alleles in a cohort of Chinese rhesus macaques. Immunogenetics (2013) 0.78
Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer. Hum Genomics (2015) 0.78
Identifying human-rhesus macaque gene orthologs using heterospecific SNP probes. Genomics (2012) 0.78
Expression sequence tag library derived from peripheral blood mononuclear cells of the chlorocebus sabaeus. BMC Genomics (2012) 0.78
Correlation of thoracic radiograph measurements with age in adolescent Chinese rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci (2013) 0.78
The genome of the vervet (Chlorocebus aethiops sabaeus). Genome Res (2015) 0.78
Differential recombination dynamics within the MHC of macaque species. Immunogenetics (2014) 0.77
Deep RNA sequencing reveals complex transcriptional landscape of a bat adenovirus. J Virol (2012) 0.77
Comparative microRNA expression profiles of cynomolgus monkeys, rat, and human reveal that mir-182 is involved in T2D pathogenic processes. J Diabetes Res (2014) 0.77
Evaluation of cynomolgus macaque (Macaca fascicularis) endogenous retrovirus expression following simian immunodeficiency virus infection. PLoS One (2012) 0.77
Why does a protein's evolutionary rate vary over time? Genome Biol Evol (2013) 0.77
Genomewide ancestry and divergence patterns from low-coverage sequencing data reveal a complex history of admixture in wild baboons. Mol Ecol (2016) 0.76
Evolutionary survey of druggable protein targets with respect to their subcellular localizations. Genome Biol Evol (2013) 0.76
Primate genomes for biomedicine. Nat Biotechnol (2011) 0.76
Novel humanized anti-CD20 antibody BM-ca binds to a unique epitope and exerts stronger cellular activity than others. Cancer Med (2013) 0.76
Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells. Lipids Health Dis (2013) 0.76
Evolutionary distance of amino acid sequence orthologs across macaque subspecies: identifying candidate genes for SIV resistance in Chinese rhesus macaques. PLoS One (2015) 0.75
Repertoire comparison of the B-cell receptor-encoding loci in humans and rhesus macaques by next-generation sequencing. Clin Transl Immunology (2016) 0.75
Genetic diversity and differentiation of the rhesus macaque (Macaca mulatta) population in western Sichuan, China, based on the second exon of the major histocompatibility complex class II DQB (MhcMamu-DQB1) alleles. BMC Evol Biol (2014) 0.75
RhesusBase PopGateway: Genome-Wide Population Genetics Atlas in Rhesus Macaque. Mol Biol Evol (2016) 0.75
Species specific exome probes reveal new insights in positively selected genes in nonhuman primates. Sci Rep (2016) 0.75
Genome-wide analysis of positively selected genes in seasonal and non-seasonal breeding species. PLoS One (2015) 0.75
Diversity and regulatory impact of copy number variation in the primate Macaca fascicularis. BMC Genomics (2017) 0.75
Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques. PLoS Pathog (2016) 0.75
Reproductive and developmental genomics retreat at Cornell University, 2012. Mol Reprod Dev (2012) 0.75
Emergence and evolution of inter-specific segregating retrocopies in cynomolgus monkey (Macaca fascicularis) and rhesus macaque (Macaca mulatta). Sci Rep (2016) 0.75
Age-Specific Gene Expression Profiles of Rhesus Monkey Ovaries Detected by Microarray Analysis. Biomed Res Int (2015) 0.75
Advantages of an Improved Rhesus Macaque Genome for Evolutionary Analyses. PLoS One (2016) 0.75
Infinium monkeys: Infinium 450K array for the Cynomolgus macaque (Macaca fascicularis). G3 (Bethesda) (2014) 0.75
Naturally Existing Oncolytic Virus M1 Is Nonpathogenic for the Nonhuman Primates After Multiple Rounds of Repeated Intravenous Injections. Hum Gene Ther (2016) 0.75
Identifying rhesus macaque gene orthologs using heterospecific human CNV probes. Genom Data (2015) 0.75
The mutual influences between depressed Macaca fascicularis mothers and their infants. PLoS One (2014) 0.75
Transcriptome analyses of rhesus monkey preimplantation embryos reveal a reduced capacity for DNA double-strand break repair in primate oocytes and early embryos. Genome Res (2017) 0.75
Cynomolgus macaque (Macaca fascicularis) immunoglobulin heavy chain locus description. Immunogenetics (2016) 0.75
Mitochondrial Genome and Nuclear Markers Provide New Insight into the Evolutionary History of Macaques. PLoS One (2016) 0.75
Transcriptome analyses provide insights into the phylogeny and adaptive evolution of the mangrove fern genus Acrostichum. Sci Rep (2016) 0.75
Single nucleotide polymorphisms in the FcγR3A and TAP1 genes impact ADCC in cynomolgus monkey PBMCs. Immunogenetics (2017) 0.75
A comprehensive profiling of T- and B-lymphocyte receptor repertoires from a Chinese-origin rhesus macaque by high-throughput sequencing. PLoS One (2017) 0.75
Mauritian cynomolgus macaques with M3M4 MHC genotype control SIVmac251 infection. J Med Primatol (2017) 0.75
Whole genome sequencing predicts novel human disease models in rhesus macaques. Genomics (2017) 0.75
ABO Blood Group Phenotype Frequency Estimation Using Molecular Phenotyping in Rhesus and Cynomolgus Macaques. HLA (2017) 0.75
Genome-wide mining and comparative analysis of microsatellites in three macaque species. Mol Genet Genomics (2017) 0.75
De novo assembly of human genomes with massively parallel short read sequencing. Genome Res (2009) 45.91
SOAP2: an improved ultrafast tool for short read alignment. Bioinformatics (2009) 39.47
Generating samples under a Wright-Fisher neutral model of genetic variation. Bioinformatics (2002) 34.50
A test of neutral molecular evolution based on nucleotide data. Genetics (1987) 24.44
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
SNP detection for massively parallel whole-genome resequencing. Genome Res (2009) 15.96
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
A molecular timescale for vertebrate evolution. Nature (1998) 13.92
A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction. Curr Biol (2005) 5.24
TTD: Therapeutic Target Database. Nucleic Acids Res (2002) 4.91
Evolution of primate gene expression. Nat Rev Genet (2006) 3.04
Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques. Science (2007) 2.62
Inference of historical changes in migration rate from the lengths of migrant tracts. Genetics (2008) 2.53
Host restriction factors blocking retroviral replication. Annu Rev Genet (2008) 2.41
TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys. PLoS Pathog (2010) 2.33
Evolution of a TRIM5-CypA splice isoform in old world monkeys. PLoS Pathog (2008) 2.20
Use of primates in research: a global overview. Am J Primatol (2004) 1.79
Adaptation and constraint at Toll-like receptors in primates. Mol Biol Evol (2010) 1.34
Assessing natural introgression in 2 biomedical model species, the rhesus macaque (Macaca mulatta) and the long-tailed macaque (Macaca fascicularis). J Hered (2008) 1.24
Divergence population genetic analysis of hybridization between rhesus and cynomolgus macaques. Mol Ecol (2009) 1.21
Physiology and Endocrinology of the Ovarian Cycle in Macaques. Toxicol Pathol (2008) 1.14
Fibroblast growth factor receptors and their ligands in the adult rat kidney. Kidney Int (2001) 1.06
Teriparatide (biosynthetic human parathyroid hormone 1-34): a new paradigm in the treatment of osteoporosis. Basic Clin Pharmacol Toxicol (2004) 1.00
Effect of genetic factors on opioid action. Curr Opin Anaesthesiol (2009) 0.91
The gene encoding the human corticostatin HP-4 precursor contains a recent 86-base duplication and is located on chromosome 8. Mol Endocrinol (1993) 0.82
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
SOAP: short oligonucleotide alignment program. Bioinformatics (2008) 68.13
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
De novo assembly of human genomes with massively parallel short read sequencing. Genome Res (2009) 45.91
A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
SOAP2: an improved ultrafast tool for short read alignment. Bioinformatics (2009) 39.47
Enterotypes of the human gut microbiome. Nature (2011) 24.36
SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler. Gigascience (2012) 20.89
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res (2008) 20.59
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A (2002) 20.48
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature (2012) 18.23
Evolution of genes and genomes on the Drosophila phylogeny. Nature (2007) 18.01
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (2012) 17.12
The Genome sequence of the SARS-associated coronavirus. Science (2003) 16.68
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA (2003) 16.08
SNP detection for massively parallel whole-genome resequencing. Genome Res (2009) 15.96
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
WEGO: a web tool for plotting GO annotations. Nucleic Acids Res (2006) 13.06
Mapping copy number variation by population-scale genome sequencing. Nature (2011) 12.55
A systematic survey of loss-of-function variants in human protein-coding genes. Science (2012) 12.25
A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature (2012) 11.68
Sequencing of 50 human exomes reveals adaptation to high altitude. Science (2010) 11.27
Bayes empirical bayes inference of amino acid sites under positive selection. Mol Biol Evol (2005) 11.26
Natural selection on protein-coding genes in the human genome. Nature (2005) 10.84
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature (2010) 10.66
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell (2006) 10.50
Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature (2007) 10.40
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science (2002) 9.59
Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios. Science (2003) 9.20
The use of coded PCR primers enables high-throughput sequencing of multiple homolog amplification products by 454 parallel sequencing. PLoS One (2007) 9.17
Assessing the evolutionary impact of amino acid mutations in the human genome. PLoS Genet (2008) 8.92
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature (2007) 8.88
TreeFam: a curated database of phylogenetic trees of animal gene families. Nucleic Acids Res (2006) 8.83
Evaluation of an improved branch-site likelihood method for detecting positive selection at the molecular level. Mol Biol Evol (2005) 8.74
Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Res (2005) 8.38
The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23
The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94
Multilocus methods for estimating population sizes, migration rates and divergence time, with applications to the divergence of Drosophila pseudoobscura and D. persimilis. Genetics (2004) 7.79
Genome sequence and analysis of the tuber crop potato. Nature (2011) 7.77
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature (2010) 7.51
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res (2008) 7.45
Modelling schizophrenia using human induced pluripotent stem cells. Nature (2011) 7.41
Codon-substitution models for detecting molecular adaptation at individual sites along specific lineages. Mol Biol Evol (2002) 7.21
The evolution of gene expression levels in mammalian organs. Nature (2011) 7.16
Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med (2011) 7.11
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet (2010) 7.08
Richness of human gut microbiome correlates with metabolic markers. Nature (2013) 6.93
TreeFam: 2008 Update. Nucleic Acids Res (2007) 6.63
Ascertainment bias in studies of human genome-wide polymorphism. Genome Res (2005) 6.63
A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
Proportionally more deleterious genetic variation in European than in African populations. Nature (2008) 6.61
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron (2007) 6.60
Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in China. N Engl J Med (2009) 6.45
A distinct lineage of influenza A virus from bats. Proc Natl Acad Sci U S A (2012) 6.27
Simultaneous inference of selection and population growth from patterns of variation in the human genome. Proc Natl Acad Sci U S A (2005) 5.94
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet (2011) 5.73
Trends in survival after in-hospital cardiac arrest. N Engl J Med (2012) 5.67
Integration within the Felsenstein equation for improved Markov chain Monte Carlo methods in population genetics. Proc Natl Acad Sci U S A (2007) 5.64
Characterization of human metapneumoviruses isolated from patients in North America. J Infect Dis (2002) 5.64
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell (2012) 5.62
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Building the sequence map of the human pan-genome. Nat Biotechnol (2009) 5.53
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (2010) 5.50
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med (2003) 5.45
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. Nat Genet (2010) 5.44
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24