Published in J Am Chem Soc on September 02, 2009
Sustained release nitric oxide from long-lived circulating nanoparticles. Free Radic Biol Med (2010) 1.71
Mechanisms of nitrite bioactivation. Nitric Oxide (2013) 1.22
Low NO concentration dependence of reductive nitrosylation reaction of hemoglobin. J Biol Chem (2012) 1.20
HBOC vasoactivity: interplay between nitric oxide scavenging and capacity to generate bioactive nitric oxide species. Antioxid Redox Signal (2013) 0.89
NO reactions with sol-gel and solution phase samples of the ferric nitrite derivative of HbA. Nitric Oxide (2009) 0.89
Mechanisms of human erythrocytic bioactivation of nitrite. J Biol Chem (2014) 0.88
An electron paramagnetic resonance study of the affinity of nitrite for methemoglobin. Nitric Oxide (2009) 0.87
Glass matrix-facilitated thermal reduction: a tool for probing reactions of met hemoglobin with nitrite and nitric oxide. J Phys Chem B (2010) 0.85
Hemoglobin as a nitrite anhydrase: modeling methemoglobin-mediated N2O3 formation. Chemistry (2011) 0.85
Generating S-nitrosothiols from hemoglobin: mechanisms, conformational dependence, and physiological relevance. J Biol Chem (2013) 0.82
Evaluating the capacity to generate and preserve nitric oxide bioactivity in highly purified earthworm erythrocruorin: a giant polymeric hemoglobin with potential blood substitute properties. J Biol Chem (2014) 0.76
Biodegradable Nanoparticles for Delivery of Therapeutics in CNS Infection. J Neuroimmune Pharmacol (2016) 0.75
Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins. Anal Chem (1998) 4.77
Slaving: solvent fluctuations dominate protein dynamics and functions. Proc Natl Acad Sci U S A (2002) 3.40
Reactions between nitric oxide and haemoglobin under physiological conditions. Nature (1998) 3.13
Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine. Proc Natl Acad Sci U S A (1993) 2.94
Bulk-solvent and hydration-shell fluctuations, similar to alpha- and beta-fluctuations in glasses, control protein motions and functions. Proc Natl Acad Sci U S A (2004) 2.54
Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin. Nat Chem Biol (2007) 2.30
An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate. Proc Natl Acad Sci U S A (2006) 2.21
Protein folding is slaved to solvent motions. Proc Natl Acad Sci U S A (2006) 1.88
Kinetic and mechanistic studies of the NO*-mediated oxidation of oxymyoglobin and oxyhemoglobin. Biochemistry (2001) 1.81
Unraveling the reactions of nitric oxide, nitrite, and hemoglobin in physiology and therapeutics. Arterioscler Thromb Vasc Biol (2006) 1.79
Protein reaction kinetics in a room-temperature glass. Science (1995) 1.77
A reduction of protein specific motions in co-ligated myoglobin embedded in a trehalose glass. Eur Biophys J (1998) 1.35
Assessments of the chemistry and vasodilatory activity of nitrite with hemoglobin under physiologically relevant conditions. J Inorg Biochem (2005) 1.30
Hydration, slaving and protein function. Biophys Chem (2002) 1.17
A hierarchy of functionally important relaxations within myoglobin based on solvent effects, mutations and kinetic model. Biochim Biophys Acta (2005) 1.08
The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities. J Biol Chem (2005) 1.05
Protein dynamics and function: insights from the energy landscape and solvent slaving. IUBMB Life (2007) 1.02
Internal dynamics and protein-matrix coupling in trehalose-coated proteins. Biochim Biophys Acta (2005) 1.01
Quantification of intermediates formed during the reduction of nitrite by deoxyhemoglobin. J Biol Chem (2009) 1.01
Intermediates detected by visible spectroscopy during the reaction of nitrite with deoxyhemoglobin: the effect of nitrite concentration and diphosphoglycerate. Biochemistry (2007) 1.01
Conformational dependence of hemoglobin reactivity under high viscosity conditions: the role of solvent slaved dynamics. J Am Chem Soc (2007) 0.94
Polyethylene glycol conjugation enhances the nitrite reductase activity of native and cross-linked hemoglobin. Biochemistry (2008) 0.93
Ligand recombination and a hierarchy of solvent slaved dynamics: the origin of kinetic phases in hemeproteins. Gene (2007) 0.90
Trehalose glass-facilitated thermal reduction of metmyoglobin and methemoglobin. J Am Chem Soc (2002) 0.89
Sugar-derived glasses support thermal and photo-initiated electron transfer processes over macroscopic distances. J Biol Chem (2006) 0.89
Comments on the physics and chemistry of trehalose as a storage medium for hemoglobin-based blood substitutes: "from Kramers Theory to the Battlefield". Transfus Clin Biol (1995) 0.81
Antimicrobial and healing efficacy of sustained release nitric oxide nanoparticles against Staphylococcus aureus skin infection. J Invest Dermatol (2009) 2.16
Sustained release nitric oxide from long-lived circulating nanoparticles. Free Radic Biol Med (2010) 1.71
Susceptibility of Gram-positive and -negative bacteria to novel nitric oxide-releasing nanoparticle technology. Virulence (2011) 1.63
Sustained release nitric oxide releasing nanoparticles: characterization of a novel delivery platform based on nitrite containing hydrogel/glass composites. Nitric Oxide (2008) 1.50
The use of nitric oxide releasing nanoparticles as a treatment against Acinetobacter baumannii in wound infections. Virulence (2010) 1.18
Nitric oxide releasing nanoparticles are therapeutic for Staphylococcus aureus abscesses in a murine model of infection. PLoS One (2009) 1.11
A hierarchy of functionally important relaxations within myoglobin based on solvent effects, mutations and kinetic model. Biochim Biophys Acta (2005) 1.08
Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model. J Infect Dis (2010) 1.06
The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities. J Biol Chem (2005) 1.05
A pathway of structural changes produced by monastrol binding to Eg5. J Biol Chem (2006) 1.04
Oral ectomesenchymal chondromyxoid tumor: case report and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 1.04
Nitric oxide-releasing nanoparticles accelerate wound healing by promoting fibroblast migration and collagen deposition. Am J Pathol (2012) 1.03
Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide. Am J Physiol Heart Circ Physiol (2010) 1.02
Spectroscopically and kinetically distinct conformational populations of sol-gel-encapsulated carbonmonoxy myoglobin. A comparison with hemoglobin. J Biol Chem (2002) 1.02
Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. Protein J (2005) 1.01
Nitrite reductase activity of sol-gel-encapsulated deoxyhemoglobin. Influence of quaternary and tertiary structure. J Biol Chem (2006) 1.01
Modulation of reactivity and conformation within the T-quaternary state of human hemoglobin: the combined use of mutagenesis and sol-gel encapsulation. Biochemistry (2006) 0.98
Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins. J Inorg Biochem (2005) 0.97
Reactions of Mycobacterium tuberculosis truncated hemoglobin O with ligands reveal a novel ligand-inclusive hydrogen bond network. Biochemistry (2003) 0.94
Conformational dependence of hemoglobin reactivity under high viscosity conditions: the role of solvent slaved dynamics. J Am Chem Soc (2007) 0.94
The use of chitosan to damage Cryptococcus neoformans biofilms. Biomaterials (2009) 0.93
Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels. Biochemistry (2004) 0.93
Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice. Nanomedicine (2012) 0.92
Exogenous nitric oxide prevents cardiovascular collapse during hemorrhagic shock. Resuscitation (2011) 0.91
Ligand recombination and a hierarchy of solvent slaved dynamics: the origin of kinetic phases in hemeproteins. Gene (2007) 0.90
Sugar-derived glasses support thermal and photo-initiated electron transfer processes over macroscopic distances. J Biol Chem (2006) 0.89
Trehalose glass-facilitated thermal reduction of metmyoglobin and methemoglobin. J Am Chem Soc (2002) 0.89
HBOC vasoactivity: interplay between nitric oxide scavenging and capacity to generate bioactive nitric oxide species. Antioxid Redox Signal (2013) 0.89
Enhanced molecular volume of conservatively pegylated Hb: (SP-PEG5K)6-HbA is non-hypertensive. Artif Cells Blood Substit Immobil Biotechnol (2005) 0.89
NO reactions with sol-gel and solution phase samples of the ferric nitrite derivative of HbA. Nitric Oxide (2009) 0.89
Functional and spectroscopic characterization of half-liganded iron-zinc hybrid hemoglobin: evidence for conformational plasticity within the T state. Biochemistry (2003) 0.87
Geminate rebinding in trehalose-glass embedded myoglobins reveals residue-specific control of intramolecular trajectories. J Mol Biol (2002) 0.86
Glass matrix-facilitated thermal reduction: a tool for probing reactions of met hemoglobin with nitrite and nitric oxide. J Phys Chem B (2010) 0.85
UV resonance Raman study of beta93-modified hemoglobin A: chemical modifier-specific effects and added influences of attached poly(ethylene glycol) chains. Biochemistry (2002) 0.85
Binding and release of iron by gel-encapsulated human transferrin: evidence for a conformational search. Proc Natl Acad Sci U S A (2002) 0.84
Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways. Biochemistry (2004) 0.84
Osmolyte-induced perturbations of hydrogen bonding between hydration layer waters: correlation with protein conformational changes. J Phys Chem B (2009) 0.84
The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species--oxygen-binding equilibria, kinetics and molecular dynamics. FEBS J (2009) 0.84
The absence of proximal strain in the truncated hemoglobins from Mycobacterium tuberculosis. J Am Chem Soc (2004) 0.84
Molecular level probing of preferential hydration and its modulation by osmolytes through the use of pyranine complexed to hemoglobin. J Biol Chem (2006) 0.83
Improved antimicrobial efficacy with nitric oxide releasing nanoparticle generated S-nitrosoglutathione. Nitric Oxide (2011) 0.83
Enhanced nitrite reductase activity associated with the haptoglobin complexed hemoglobin dimer: functional and antioxidative implications. Nitric Oxide (2012) 0.83
Semihemoglobins, high oxygen affinity dimeric forms of human hemoglobin respond efficiently to allosteric effectors without forming tetramers. J Biol Chem (2004) 0.83
Kinetic modulation in carbonmonoxy derivatives of truncated hemoglobins: the role of distal heme pocket residues and extended apolar tunnel. J Biol Chem (2003) 0.83
Structural and functional studies indicating altered redox properties of hemoglobin E: implications for production of bioactive nitric oxide. J Biol Chem (2011) 0.83
Nitric oxide nanoparticles: pre-clinical utility as a therapeutic for intramuscular abscesses. Virulence (2012) 0.82
Generating S-nitrosothiols from hemoglobin: mechanisms, conformational dependence, and physiological relevance. J Biol Chem (2013) 0.82
Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis. J Biol Chem (2004) 0.82
Nitric oxide releasing nanoparticle synthesis and characterization. Methods Mol Biol (2011) 0.81
A nanoparticle delivery vehicle for S-nitroso-N-acetyl cysteine: sustained vascular response. Nitric Oxide (2012) 0.81
Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water. J Biol Chem (2008) 0.81
Probing the conformation of hemoglobin presbyterian in the R-state. J Protein Chem (2003) 0.81
Intersubunit interactions associated with Tyr42 alpha stabilize the quaternary-T tetramer but are not major quaternary constraints in deoxyhemoglobin. Biochemistry (2005) 0.80
Proximal ligand motions in H93G myoglobin. Eur J Biochem (2002) 0.80
Multiple active site conformers in the carbon monoxide complexes of trematode hemoglobins. J Biol Chem (2006) 0.79
Distal heme pocket conformers of carbonmonoxy derivatives of Ascaris hemoglobin: evidence of conformational trapping in porous sol-gel matrices. J Biol Chem (2003) 0.79
Nitrosoglutathione generating nitric oxide nanoparticles as an improved strategy for combating Pseudomonas aeruginosa-infected wounds. J Drugs Dermatol (2012) 0.77
Proteins in motion: resonance Raman spectroscopy as a probe of functional intermediates. Methods Mol Biol (2005) 0.77
Combining the influence of two low O2 affinity-inducing chemical modifications of the central cavity of hemoglobin. Biochemistry (2007) 0.77
Charge density-dependent modifications of hydration shell waters by Hofmeister ions. J Am Chem Soc (2009) 0.77
Conformational changes in hemoglobin S (betaE6V) imposed by mutation of the beta Glu7-beta Lys132 salt bridge and detected by UV resonance Raman spectroscopy. J Biol Chem (2002) 0.77
Localized increase of tissue oxygen tension by magnetic targeted drug delivery. Nanotechnology (2014) 0.76
Rationale for early versus late intervention with arthroscopy for treatment of inflammatory/degenerative temporomandibular joint disorders. J Oral Maxillofac Surg (2010) 0.76
Posttransfusion Increase of Hematocrit per se Does Not Improve Circulatory Oxygen Delivery due to Increased Blood Viscosity. Anesth Analg (2017) 0.76
Dilate, dilute, constrict, or else in treating hemorrhage? Crit Care Med (2011) 0.75
Similar experience. N Y State Dent J (2010) 0.75
Reverse micelles as a tool for probing solvent modulation of protein dynamics: Reverse micelle encapsulated hemoglobin. Chem Phys (2013) 0.75
Cavernous sinus thrombosis secondary to fracture of posterior maxillary sinus wall. Case report. N Y State Dent J (2009) 0.75
A conversation with NYSDA President Joel M. Friedman, D.D.S. N Y State Dent J (2013) 0.75