Published in J Biol Chem on December 16, 2002
Sickle-cell disease. Lancet (2004) 4.76
Antimicrobial and healing efficacy of sustained release nitric oxide nanoparticles against Staphylococcus aureus skin infection. J Invest Dermatol (2009) 2.16
Sustained release nitric oxide from long-lived circulating nanoparticles. Free Radic Biol Med (2010) 1.71
Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice. J Clin Invest (2004) 1.67
Susceptibility of Gram-positive and -negative bacteria to novel nitric oxide-releasing nanoparticle technology. Virulence (2011) 1.63
Large-scale production of embryonic red blood cells from human embryonic stem cells. Exp Hematol (2006) 1.61
Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells. Proc Natl Acad Sci U S A (2002) 1.61
Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J Cell Biol (2008) 1.52
Sustained release nitric oxide releasing nanoparticles: characterization of a novel delivery platform based on nitrite containing hydrogel/glass composites. Nitric Oxide (2008) 1.50
Liquid-liquid separation in solutions of normal and sickle cell hemoglobin. Proc Natl Acad Sci U S A (2002) 1.50
High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells. J Clin Invest (2004) 1.35
Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren. Am J Trop Med Hyg (2003) 1.31
The use of nitric oxide releasing nanoparticles as a treatment against Acinetobacter baumannii in wound infections. Virulence (2010) 1.18
Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity. Blood (2002) 1.13
Nitric oxide releasing nanoparticles are therapeutic for Staphylococcus aureus abscesses in a murine model of infection. PLoS One (2009) 1.11
The kinetics of nucleation and growth of sickle cell hemoglobin fibers. J Mol Biol (2006) 1.09
A hierarchy of functionally important relaxations within myoglobin based on solvent effects, mutations and kinetic model. Biochim Biophys Acta (2005) 1.08
Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model. J Infect Dis (2010) 1.06
The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities. J Biol Chem (2005) 1.05
A pathway of structural changes produced by monastrol binding to Eg5. J Biol Chem (2006) 1.04
Oral ectomesenchymal chondromyxoid tumor: case report and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 1.04
Metastable mesoscopic clusters in solutions of sickle-cell hemoglobin. Biophys J (2006) 1.04
Nitric oxide-releasing nanoparticles accelerate wound healing by promoting fibroblast migration and collagen deposition. Am J Pathol (2012) 1.03
Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide. Am J Physiol Heart Circ Physiol (2010) 1.02
Two-step mechanism of homogeneous nucleation of sickle cell hemoglobin polymers. Biophys J (2007) 1.02
Spectroscopically and kinetically distinct conformational populations of sol-gel-encapsulated carbonmonoxy myoglobin. A comparison with hemoglobin. J Biol Chem (2002) 1.02
Implications of the genetic epidemiology of globin haplotypes linked to the sickle cell gene in southern Iran. Hum Biol (2006) 1.01
Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. Protein J (2005) 1.01
Nitrite reductase activity of sol-gel-encapsulated deoxyhemoglobin. Influence of quaternary and tertiary structure. J Biol Chem (2006) 1.01
Heme degradation and oxidative stress in murine models for hemoglobinopathies: thalassemia, sickle cell disease and hemoglobin C disease. Blood Cells Mol Dis (2008) 1.00
Hemoglobinopathies. Hematology Am Soc Hematol Educ Program (2003) 1.00
Modulation of reactivity and conformation within the T-quaternary state of human hemoglobin: the combined use of mutagenesis and sol-gel encapsulation. Biochemistry (2006) 0.98
Hemoglobin Porto Alegre forms a tetramer of tetramers superstructure. Protein Sci (2002) 0.98
Estimated glomerular filtration rate in sickle cell anemia is associated with polymorphisms of bone morphogenetic protein receptor 1B. Am J Hematol (2007) 0.97
Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins. J Inorg Biochem (2005) 0.97
Plasma lipids in Iranians with sickle cell disease: hypocholesterolemia in sickle cell anemia and increase of HDL-cholesterol in sickle cell trait. Clin Chim Acta (2005) 0.96
Intermolecular interactions, nucleation, and thermodynamics of crystallization of hemoglobin C. Biophys J (2002) 0.95
Conformational dependence of hemoglobin reactivity under high viscosity conditions: the role of solvent slaved dynamics. J Am Chem Soc (2007) 0.94
Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells. Blood (2003) 0.94
Reactivity of glass-embedded met hemoglobin derivatives toward external NO: implications for nitrite-mediated production of bioactive NO. J Am Chem Soc (2009) 0.94
Reactions of Mycobacterium tuberculosis truncated hemoglobin O with ligands reveal a novel ligand-inclusive hydrogen bond network. Biochemistry (2003) 0.94
Exogenous iron increases hemoglobin in beta-thalassemic mice. Exp Hematol (2008) 0.94
The use of chitosan to damage Cryptococcus neoformans biofilms. Biomaterials (2009) 0.93
Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels. Biochemistry (2004) 0.93
Mechanisms for sickle red blood cell retention in choroid. Curr Eye Res (2002) 0.93
Inhibition of sickle red cell adhesion and vasoocclusion in the microcirculation by antioxidants. Am J Physiol Heart Circ Physiol (2006) 0.93
Nitric oxide-releasing nanoparticles accelerate wound healing in NOD-SCID mice. Nanomedicine (2012) 0.92
Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Kurdish population of Western Iran. Blood Cells Mol Dis (2006) 0.92
Exogenous nitric oxide prevents cardiovascular collapse during hemorrhagic shock. Resuscitation (2011) 0.91
Caspase 3-mediated proteolysis of the N-terminal cytoplasmic domain of the human erythroid anion exchanger 1 (band 3). J Biol Chem (2003) 0.90
Ligand recombination and a hierarchy of solvent slaved dynamics: the origin of kinetic phases in hemeproteins. Gene (2007) 0.90
Trehalose glass-facilitated thermal reduction of metmyoglobin and methemoglobin. J Am Chem Soc (2002) 0.89
Enhanced molecular volume of conservatively pegylated Hb: (SP-PEG5K)6-HbA is non-hypertensive. Artif Cells Blood Substit Immobil Biotechnol (2005) 0.89
HBOC vasoactivity: interplay between nitric oxide scavenging and capacity to generate bioactive nitric oxide species. Antioxid Redox Signal (2013) 0.89
Sugar-derived glasses support thermal and photo-initiated electron transfer processes over macroscopic distances. J Biol Chem (2006) 0.89
NO reactions with sol-gel and solution phase samples of the ferric nitrite derivative of HbA. Nitric Oxide (2009) 0.89
Acellular invertebrate hemoglobins as model therapeutic oxygen carriers: unique redox potentials. Artif Cells Blood Substit Immobil Biotechnol (2007) 0.88
Functional and spectroscopic characterization of half-liganded iron-zinc hybrid hemoglobin: evidence for conformational plasticity within the T state. Biochemistry (2003) 0.87
Transgenic mice and hemoglobinopathies. Methods Mol Med (2003) 0.86
Geminate rebinding in trehalose-glass embedded myoglobins reveals residue-specific control of intramolecular trajectories. J Mol Biol (2002) 0.86
An Iranian child with HbQ-Iran [alpha75 (EF4) Asp-->His]/-alpha3.7 kb/IVSII.1 G-->A: first report. J Pediatr Hematol Oncol (2007) 0.86
Neuroglobin ligand binding kinetics. IUBMB Life (2005) 0.85
Glass matrix-facilitated thermal reduction: a tool for probing reactions of met hemoglobin with nitrite and nitric oxide. J Phys Chem B (2010) 0.85
UV resonance Raman study of beta93-modified hemoglobin A: chemical modifier-specific effects and added influences of attached poly(ethylene glycol) chains. Biochemistry (2002) 0.85
Prevalence of factor V Leiden (G1691A) and prothrombin (G20210A) among Kurdish population from Western Iran. J Thromb Thrombolysis (2007) 0.85
Binding and release of iron by gel-encapsulated human transferrin: evidence for a conformational search. Proc Natl Acad Sci U S A (2002) 0.84
Liganded hemoglobin structural perturbations by the allosteric effector L35. Biophys J (2004) 0.84
The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species--oxygen-binding equilibria, kinetics and molecular dynamics. FEBS J (2009) 0.84
Thrombophilic mutations among Southern Iranian patients with sickle cell disease: high prevalence of factor V Leiden. J Thromb Thrombolysis (2007) 0.84
Osmolyte-induced perturbations of hydrogen bonding between hydration layer waters: correlation with protein conformational changes. J Phys Chem B (2009) 0.84
Domain-specific effector interactions within the central cavity of human adult hemoglobin in solution and in porous sol-gel matrices: evidence for long-range communication pathways. Biochemistry (2004) 0.84
The absence of proximal strain in the truncated hemoglobins from Mycobacterium tuberculosis. J Am Chem Soc (2004) 0.84
The beta-globin gene haplotypes associated with Hb D-Los Angeles [beta121(GH4)Glu --> Gln] in Western Iran. Hemoglobin (2006) 0.84
Origin of Hb A2' (Hb B2) [delta16(A13)Gly --> Arg (GGC --> CGC)]. Hemoglobin (2003) 0.83
Kinetic modulation in carbonmonoxy derivatives of truncated hemoglobins: the role of distal heme pocket residues and extended apolar tunnel. J Biol Chem (2003) 0.83
Liquid-liquid phase separation in hemoglobins: distinct aggregation mechanisms of the beta6 mutants. Biophys J (2004) 0.83
Molecular level probing of preferential hydration and its modulation by osmolytes through the use of pyranine complexed to hemoglobin. J Biol Chem (2006) 0.83
Improved antimicrobial efficacy with nitric oxide releasing nanoparticle generated S-nitrosoglutathione. Nitric Oxide (2011) 0.83
Enhanced nitrite reductase activity associated with the haptoglobin complexed hemoglobin dimer: functional and antioxidative implications. Nitric Oxide (2012) 0.83
Semihemoglobins, high oxygen affinity dimeric forms of human hemoglobin respond efficiently to allosteric effectors without forming tetramers. J Biol Chem (2004) 0.83
Structural and functional studies indicating altered redox properties of hemoglobin E: implications for production of bioactive nitric oxide. J Biol Chem (2011) 0.83
Human and mouse hemoglobin association with the transgenic mouse erythrocyte membrane. FEBS Lett (2006) 0.82
Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis. J Biol Chem (2004) 0.82
Nitric oxide nanoparticles: pre-clinical utility as a therapeutic for intramuscular abscesses. Virulence (2012) 0.82
Generating S-nitrosothiols from hemoglobin: mechanisms, conformational dependence, and physiological relevance. J Biol Chem (2013) 0.82
Differential gene expression in the kidney of sickle cell transgenic mice: upregulated genes. Blood Cells Mol Dis (2003) 0.81
Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water. J Biol Chem (2008) 0.81
Nitric oxide releasing nanoparticle synthesis and characterization. Methods Mol Biol (2011) 0.81
Decreased cerebral perfusion correlates with increased BOLD hyperoxia response in transgenic mouse models of sickle cell disease. Magn Reson Med (2004) 0.81
A nanoparticle delivery vehicle for S-nitroso-N-acetyl cysteine: sustained vascular response. Nitric Oxide (2012) 0.81
Probing the conformation of hemoglobin presbyterian in the R-state. J Protein Chem (2003) 0.81
COHbC and COHbS crystallize in the R2 quaternary state at neutral pH in the presence of PEG 4000. Acta Crystallogr D Biol Crystallogr (2005) 0.81