Published in J Genet Genomics on August 01, 2009
Nonsense-mediated decay enables intron gain in Drosophila. PLoS Genet (2010) 1.17
Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med (2002) 21.28
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet (2009) 7.48
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat Genet (2013) 4.48
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines. J Natl Cancer Inst (2010) 2.79
The iron chelator deferasirox protects mice from mucormycosis through iron starvation. J Clin Invest (2007) 2.48
Oct4 pseudogenes are transcribed in cancers. Biochem Biophys Res Commun (2005) 2.34
ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells. EMBO Rep (2006) 2.26
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res (2012) 2.26
Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology (2012) 2.11
Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. Cancer Cell (2009) 2.10
Mutations in NR5A1 associated with ovarian insufficiency. N Engl J Med (2009) 1.88
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene. Oncogene (2004) 1.83
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res (2009) 1.82
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest (2009) 1.80
The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus. Infect Immun (2008) 1.77
Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology. Stem Cells (2010) 1.74
Draft genome of the kiwifruit Actinidia chinensis. Nat Commun (2013) 1.72
Method development of efficient protein extraction in bone tissue for proteome analysis. J Proteome Res (2007) 1.71
Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency. J Clin Endocrinol Metab (2009) 1.68
Two small GTPases act in concert with the bactofilin cytoskeleton to regulate dynamic bacterial cell polarity. Dev Cell (2013) 1.63
Gene amplification in esophageal adenocarcinomas and Barrett's with high-grade dysplasia. Clin Cancer Res (2003) 1.62
Mutations in the p53 tumor suppressor gene and early onset breast cancer. Cancer Biol Ther (2002) 1.52
Assessment of ischemia-modified albumin levels for emergency room diagnosis of acute coronary syndrome. Int J Cardiol (2010) 1.49
Glycoproteomic reactor for human plasma. J Proteome Res (2009) 1.49
Improved neovascularization and wound repair by targeting human basic fibroblast growth factor (bFGF) to fibrin. J Mol Med (Berl) (2008) 1.46
Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. J Clin Invest (2012) 1.45
Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas. Proc Natl Acad Sci U S A (2005) 1.44
Highly efficient extraction of serum peptides by ordered mesoporous carbon. Angew Chem Int Ed Engl (2011) 1.43
Long noncoding RNAs in development and disease of the central nervous system. Trends Genet (2013) 1.42
DNA origami as a carrier for circumvention of drug resistance. J Am Chem Soc (2012) 1.42
miR-135a Suppresses Calcification in Senescent VSMCs by Regulating KLF4/STAT3 Pathway. Curr Vasc Pharmacol (2016) 1.42
NANOGP8 is a retrogene expressed in cancers. FEBS J (2006) 1.40
Hierarchical modeling for rare event detection and cell subset alignment across flow cytometry samples. PLoS Comput Biol (2013) 1.35
Human male infertility associated with mutations in NR5A1 encoding steroidogenic factor 1. Am J Hum Genet (2010) 1.35
Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair. J Biol Chem (2010) 1.34
Alternative translation of OCT4 by an internal ribosome entry site and its novel function in stress response. Stem Cells (2009) 1.33
Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection. PLoS One (2012) 1.32
A multi-omic map of the lipid-producing yeast Rhodosporidium toruloides. Nat Commun (2012) 1.32
NADPH oxidase contributes to renal damage and dysfunction in Dahl salt-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol (2008) 1.31
Cell death in development: shaping the embryo. Histochem Cell Biol (2006) 1.30
The enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugs. Biomaterials (2011) 1.30
DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons. Neuron (2011) 1.30
Steroidogenic factor-1 (SF-1, NR5A1) and human disease. Mol Cell Endocrinol (2010) 1.29
Type 1 ryanodine receptor in cardiac mitochondria: transducer of excitation-metabolism coupling. Biochim Biophys Acta (2005) 1.28
Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma. Neoplasia (2006) 1.28
Mutational analysis of steroidogenic factor 1 (NR5a1) in 24 boys with bilateral anorchia: a French collaborative study. Hum Reprod (2007) 1.27
The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis. Mol Microbiol (2010) 1.27
Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins. Blood (2012) 1.26
The phosphatidylinositol 3-phosphate phosphatase myotubularin- related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1. Mol Cell Biol (2005) 1.26
Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice. Kidney Int (2012) 1.25
Anaplastic large cell lymphoma involving the breast: a clinicopathologic study of 6 cases and review of the literature. Arch Pathol Lab Med (2009) 1.24
Development of efficient protein extraction methods for shotgun proteome analysis of formalin-fixed tissues. J Proteome Res (2007) 1.24
Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes. Nat Struct Mol Biol (2008) 1.23
CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma. Clin Cancer Res (2010) 1.23
The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency. Eur J Endocrinol (2009) 1.23
CD4 T cells promote tissue inflammation via CD40 signaling without de novo activation in a murine model of liver ischemia/reperfusion injury. Hepatology (2009) 1.22
Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma. Ann Thorac Surg (2012) 1.21
Elevated cysteine-rich 61 mediates aberrant collagen homeostasis in chronologically aged and photoaged human skin. Am J Pathol (2006) 1.20
A novel point mutation in the KCNJ5 gene causing primary hyperaldosteronism and early-onset autosomal dominant hypertension. J Clin Endocrinol Metab (2012) 1.20
Piglets cloned from induced pluripotent stem cells. Cell Res (2012) 1.19
Oral ginseng formulae for stable chronic obstructive pulmonary disease: a systematic review. Respir Med (2010) 1.18
Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells. Sci Rep (2013) 1.18
Five novel mutations in steroidogenic factor 1 (SF1, NR5A1) in 46,XY patients with severe underandrogenization but without adrenal insufficiency. Hum Mutat (2008) 1.18
Reversed-phase-reversed-phase liquid chromatography approach with high orthogonality for multidimensional separation of phosphopeptides. Anal Chem (2010) 1.18
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking. J Neurosci (2008) 1.18
Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw. Transgenic Res (2009) 1.17
Expression of Nanog gene promotes NIH3T3 cell proliferation. Biochem Biophys Res Commun (2005) 1.16
L1 elements, processed pseudogenes and retrogenes in mammalian genomes. IUBMB Life (2006) 1.16
Antibody titer threshold predicts anti-candidal vaccine efficacy even though the mechanism of protection is induction of cell-mediated immunity. J Infect Dis (2008) 1.15
Systematic analysis of protein phosphorylation networks from phosphoproteomic data. Mol Cell Proteomics (2012) 1.15
Bladder cancer determination via two urinary metabolites: a biomarker pattern approach. Mol Cell Proteomics (2011) 1.14
Pig transgenesis by Sleeping Beauty DNA transposition. Transgenic Res (2010) 1.13
Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin. Mol Cell Neurosci (2008) 1.12
CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis. J Biol Chem (2011) 1.12
Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc. J Clin Endocrinol Metab (2008) 1.11
Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography. Proteomics (2008) 1.11
Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway. PLoS One (2008) 1.10
Robust phosphoproteome enrichment using monodisperse microsphere-based immobilized titanium (IV) ion affinity chromatography. Nat Protoc (2013) 1.09
Giant osteomas of the ethmoid and frontal sinuses: Clinical characteristics and review of the literature. Oncol Lett (2013) 1.09
Sex differences in the symptoms and psychological factors that influence quality of life in patients with irritable bowel syndrome. Eur J Gastroenterol Hepatol (2012) 1.09
Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. J Proteome Res (2008) 1.08
SNAP-29-mediated modulation of synaptic transmission in cultured hippocampal neurons. J Biol Chem (2005) 1.08
The effects of Buyang Huanwu Decoction on hemorheological disorders and energy metabolism in rats with coronary heart disease. J Ethnopharmacol (2011) 1.07
Decreased selenium-binding protein 1 in esophageal adenocarcinoma results from posttranscriptional and epigenetic regulation and affects chemosensitivity. Clin Cancer Res (2010) 1.07
Homogeneous osteogenesis and bone regeneration by demineralized bone matrix loading with collagen-targeting bone morphogenetic protein-2. Biomaterials (2006) 1.07
Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response. Cancer Res (2009) 1.07
Anti-fatigue activity of extracts of stem bark from Acanthopanax senticosus. Molecules (2010) 1.07
Curcumin promotes apoptosis, increases chemosensitivity, and inhibits nuclear factor kappaB in esophageal adenocarcinoma. Transl Oncol (2010) 1.06
P-glycoprotein antibody functionalized carbon nanotube overcomes the multidrug resistance of human leukemia cells. ACS Nano (2010) 1.06
Expression of nesfatin-1/NUCB2 in rodent digestive system. World J Gastroenterol (2010) 1.05
Genetically modified pigs for biomedical research. J Inherit Metab Dis (2012) 1.05
Enhancing the identification of phosphopeptides from putative basophilic kinase substrates using Ti (IV) based IMAC enrichment. Mol Cell Proteomics (2011) 1.05
Immunological surrogate marker of rAls3p-N vaccine-induced protection against Staphylococcus aureus. FEMS Immunol Med Microbiol (2009) 1.05
Recent developments in methods and technology for analysis of biological samples by MALDI-TOF-MS. Anal Bioanal Chem (2006) 1.04
Development of glycoprotein capture-based label-free method for the high-throughput screening of differential glycoproteins in hepatocellular carcinoma. Mol Cell Proteomics (2011) 1.04
The effect of crosslinking heparin to demineralized bone matrix on mechanical strength and specific binding to human bone morphogenetic protein-2. Biomaterials (2008) 1.04
Phosphoproteome analysis of human liver tissue by long-gradient nanoflow LC coupled with multiple stage MS analysis. Electrophoresis (2010) 1.04
Crystal structure of the urokinase receptor in a ligand-free form. J Mol Biol (2012) 1.03