PubRank

Dominic P Kwiatkowski

Author PubWeight™ 172.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007 12.62
2 Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 2010 12.27
3 Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 2014 11.87
4 A genotype calling algorithm for the Illumina BeadArray platform. Bioinformatics 2007 8.03
5 Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nat Genet 2013 5.22
6 Severe anemia in Malawian children. N Engl J Med 2008 5.20
7 In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading. Nat Genet 2003 5.10
8 Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. Nature 2012 4.37
9 Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet 2009 4.30
10 A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat Genet 2007 4.23
11 Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia. Proc Natl Acad Sci U S A 2012 4.10
12 Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum. Nature 2011 3.83
13 Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet 2012 3.31
14 LookSeq: a browser-based viewer for deep sequencing data. Genome Res 2009 2.70
15 SNP-o-matic. Bioinformatics 2009 2.28
16 Methodological challenges of genome-wide association analysis in Africa. Nat Rev Genet 2010 2.27
17 Ethical data release in genome-wide association studies in developing countries. PLoS Med 2009 2.23
18 Optimizing Illumina next-generation sequencing library preparation for extremely AT-biased genomes. BMC Genomics 2012 2.20
19 Valid consent for genomic epidemiology in developing countries. PLoS Med 2007 2.14
20 Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility. Eur J Hum Genet 2009 1.94
21 Quantitative high-throughput analysis of transcription factor binding specificities. Nucleic Acids Res 2004 1.87
22 Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria. Hum Mol Genet 2007 1.72
23 Genomewide analysis of the host response to malaria in Kenyan children. J Infect Dis 2005 1.66
24 Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children. Blood 2008 1.56
25 Data sharing and intellectual property in a genomic epidemiology network: policies for large-scale research collaboration. Bull World Health Organ 2006 1.56
26 Haplotypic analysis of the TNF locus by association efficiency and entropy. Genome Biol 2003 1.55
27 Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites. PLoS Genet 2012 1.55
28 Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes. Hum Mol Genet 2009 1.50
29 Using CF11 cellulose columns to inexpensively and effectively remove human DNA from Plasmodium falciparum-infected whole blood samples. Malar J 2012 1.48
30 Genome-wide comparisons of variation in linkage disequilibrium. Genome Res 2009 1.43
31 Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens. PLoS Pathog 2012 1.43
32 An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing. PLoS One 2011 1.39
33 A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants. Vaccine 2012 1.39
34 Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1. Nat Genet 2004 1.37
35 Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data. PLoS One 2012 1.36
36 Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients. PLoS One 2011 1.34
37 Imputation-based meta-analysis of severe malaria in three African populations. PLoS Genet 2013 1.25
38 An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations. Genome Biol 2011 1.24
39 Association of Fcgamma receptor IIa (CD32) polymorphism with severe malaria in West Africa. Am J Trop Med Hyg 2003 1.24
40 A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection. BMC Med Genet 2006 1.21
41 Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype. PLoS Med 2006 1.21
42 Validating discovered Cis-acting regulatory genetic variants: application of an allele specific expression approach to HapMap populations. PLoS One 2008 1.20
43 Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations. J Infect Dis 2009 1.17
44 Localization of a long-range cis-regulatory element of IL13 by allelic transcript ratio mapping. Genome Res 2006 1.16
45 A novel cytofluorometric assay for the detection and quantification of glucose-6-phosphate dehydrogenase deficiency. Sci Rep 2012 1.16
46 Response of the splenic dendritic cell population to malaria infection. Infect Immun 2004 1.15
47 Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. PLoS One 2011 1.13
48 Screening for recently selected alleles by analysis of human haplotype similarity. Am J Hum Genet 2005 1.10
49 Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring. Malar J 2010 1.09
50 Power consequences of linkage disequilibrium variation between populations. Genet Epidemiol 2009 1.08
51 Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya. Sci Rep 2013 1.07
52 Detecting and characterizing genomic signatures of positive selection in global populations. Am J Hum Genet 2013 1.04
53 A novel locus of resistance to severe malaria in a region of ancient balancing selection. Nature 2015 1.03
54 Assessing genuine parents-offspring trios for genetic association studies. Hum Hered 2008 1.03
55 Whole genome-amplified DNA: insights and imputation. Nat Methods 2008 1.02
56 Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria. Hum Genet 2003 1.00
57 Haplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection. PLoS One 2007 0.99
58 Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing. PLoS One 2013 0.98
59 Plasmodium falciparum-like parasites infecting wild apes in southern Cameroon do not represent a recurrent source of human malaria. Proc Natl Acad Sci U S A 2013 0.98
60 Susceptibility to sequelae of human ocular chlamydial infection associated with allelic variation in IL10 cis-regulation. Hum Mol Genet 2007 0.97
61 Searching for the regulators of human gene expression. Bioessays 2006 0.97
62 New interventions for malaria: mining the human and parasite genomes. Am J Trop Med Hyg 2007 0.96
63 Efficient depletion of host DNA contamination in malaria clinical sequencing. J Clin Microbiol 2012 0.96
64 Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection. J Infect Dis 2013 0.95
65 Haptoglobin genotype, anaemia and malaria in Gambian children. Trop Med Int Health 2008 0.95
66 Haplotype mapping of the bronchiolitis susceptibility locus near IL8. Hum Genet 2003 0.94
67 A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility. Hum Genet 2008 0.92
68 Association of cytokine and Toll-like receptor gene polymorphisms with severe malaria in three regions of Cameroon. PLoS One 2013 0.91
69 Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya. BMC Med Genet 2014 0.91
70 Context-specific functional effects of IFNGR1 promoter polymorphism. Hum Mol Genet 2006 0.91
71 Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes. BMC Med Genet 2010 0.90
72 Improved allelic differentiation using sequence-specific oligonucleotide hybridization incorporating an additional base-analogue mismatch. Nucleosides Nucleotides Nucleic Acids 2004 0.88
73 Association of the GNAS locus with severe malaria. Hum Genet 2008 0.87
74 SnoopCGH: software for visualizing comparative genomic hybridization data. Bioinformatics 2009 0.87
75 Haplotype homozygosity and derived alleles in the human genome. Am J Hum Genet 2006 0.86
76 TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression. Malar J 2009 0.86
77 Host genetic factors in resistance and susceptibility to malaria. Parassitologia 2006 0.85
78 A Bayesian approach using covariance of single nucleotide polymorphism data to detect differences in linkage disequilibrium patterns between groups of individuals. Bioinformatics 2010 0.84
79 Comparing the fine specificity of DNA binding by NF-kappaB p50 and p52 using principal coordinates analysis. Nucleic Acids Res 2003 0.83
80 Epistasis between the haptoglobin common variant and α+thalassemia influences risk of severe malaria in Kenyan children. Blood 2014 0.82
81 Investigation of host candidate malaria-associated risk/protective SNPs in a Brazilian Amazonian population. PLoS One 2012 0.81
82 Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis. PLoS One 2010 0.81
83 Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana District of Ghana. PLoS One 2012 0.80
84 An In-Solution Hybridisation Method for the Isolation of Pathogen DNA from Human DNA-rich Clinical Samples for Analysis by NGS. Open Genomics J 2012 0.80
85 Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations. PLoS One 2009 0.80
86 Investigation of familial segregation of hyperreactive malarial splenomegaly in Kumasi, Ghana. Trans R Soc Trop Med Hyg 2005 0.80
87 Knowing who to trust: exploring the role of 'ethical metadata' in mediating risk of harm in collaborative genomics research in Africa. BMC Med Ethics 2014 0.78
88 Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study. Malar J 2014 0.78
89 Haptoglobin and sickle cell polymorphisms and risk of active trachoma in Gambian children. PLoS One 2010 0.77
90 Host candidate gene polymorphisms and clearance of drug-resistant Plasmodium falciparum parasites. Malar J 2011 0.75