PubRank

Michael C Ostrowski

Author PubWeight™ 85.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity. Circulation 2009 4.71
2 Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature 2009 4.21
3 A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood 2002 4.06
4 Extra-embryonic function of Rb is essential for embryonic development and viability. Nature 2003 3.92
5 Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res 2008 3.41
6 Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science 2009 2.76
7 Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome. Nature 2008 2.71
8 MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Mol Cell 2010 2.59
9 NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest 2008 2.29
10 Genomic alterations in tumor stroma. Cancer Res 2009 2.18
11 Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood 2009 2.17
12 Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling. J Biol Chem 2002 1.59
13 MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. J Biol Chem 2007 1.53
14 Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circ Res 2009 1.52
15 Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors. Mol Cell Biol 2007 1.43
16 ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis. Oncogene 2005 1.42
17 An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Res 2010 1.39
18 e-Science, caGrid, and Translational Biomedical Research. Computer (Long Beach Calif) 2008 1.32
19 Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors. Mol Biol Cell 2006 1.31
20 The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages. J Immunol 2004 1.31
21 Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Res 2008 1.30
22 TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy. PLoS One 2010 1.28
23 Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. J Biol Chem 2003 1.27
24 Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis. PLoS One 2009 1.26
25 Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Res 2006 1.20
26 MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. Neuro Oncol 2013 1.20
27 The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase. J Biol Chem 2004 1.18
28 Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression. J Biol Chem 2003 1.14
29 Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model. J Immunol 2004 1.14
30 The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation. Hum Mol Genet 2006 1.13
31 The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor. J Biol Chem 2006 1.12
32 NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis. J Immunol 2011 1.12
33 PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. Hum Mol Genet 2002 1.11
34 Allele-specific tumor spectrum in pten knockin mice. Proc Natl Acad Sci U S A 2010 1.08
35 Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma. Mol Ther 2013 1.07
36 CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells. J Biol Chem 2003 1.06
37 Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Res 2011 1.02
38 Transcription factor ATF3 links host adaptive response to breast cancer metastasis. J Clin Invest 2013 1.00
39 Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Mol Immunol 2005 0.99
40 NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model. Breast Cancer Res 2011 0.99
41 RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1. J Bone Miner Res 2004 0.98
42 Ets-2 interacts with co-repressor BS69 to repress target gene expression. Anticancer Res 2003 0.98
43 A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene. Mol Endocrinol 2003 0.98
44 E2f1-3 are critical for myeloid development. J Biol Chem 2010 0.97
45 The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter. J Leukoc Biol 2002 0.95
46 Loss of fibroblast HIF-1α accelerates tumorigenesis. Cancer Res 2012 0.92
47 PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter. J Cell Physiol 2008 0.91
48 Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. PLoS One 2013 0.86
49 The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts. J Leukoc Biol 2002 0.85
50 The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene. J Immunol 2008 0.85
51 Transcription factor ets-2 plays an important role in the pathogenesis of pulmonary fibrosis. Am J Respir Cell Mol Biol 2011 0.84
52 Analysis of the IKKbeta/NF-kappaB signaling pathway during embryonic angiogenesis. Dev Dyn 2008 0.84
53 Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice. J Cell Physiol 2009 0.84
54 The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma. PLoS One 2009 0.82
55 Genetics and genomics of osteoclast differentiation: integrating cell signaling pathways and gene networks. Crit Rev Eukaryot Gene Expr 2006 0.80
56 A mouse model of yellow fluorescent protein (YFP) expression in hematopoietic cells to assess leukocyte-endothelial interactions in the microcirculation. Microvasc Res 2009 0.79
57 The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF). J Biol Chem 2013 0.79
58 Setting Snail2's pace during EMT. Nat Cell Biol 2012 0.76