Published in PLoS One on September 09, 2009
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Caenorhabditis elegans susceptibility to gut Enterococcus faecalis infection is associated with fat metabolism and epithelial junction integrity. BMC Microbiol (2016) 0.76
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Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci U S A (2002) 9.78
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Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci (2003) 4.83
Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol (2001) 4.34
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature (2000) 4.00
Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J Physiol (2004) 3.52
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The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab (2006) 3.00
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Alterations in xenobiotic metabolism in the long-lived Little mice. Aging Cell (2007) 2.35
Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase. J Biol Chem (2003) 2.07
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex. Proc Natl Acad Sci U S A (2005) 1.91
Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism. Genes Dev (2001) 1.82
Gene expression profile of long-lived Ames dwarf mice and Little mice. Aging Cell (2004) 1.80
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The impact of intestinal microflora on serum bilirubin levels. J Hepatol (2005) 1.49
CAR, the continuously advancing receptor, in drug metabolism and disease. Curr Drug Metab (2005) 1.46
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Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR. Arch Biochem Biophys (2005) 1.27
Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression. Mol Pharmacol (2008) 1.24
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Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes. Pharmacogenet Genomics (2008) 1.01
Physiological function of PARbZip circadian clock-controlled transcription factors. Ann Med (2007) 0.95
Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity. Int J Obes (Lond) (2006) 0.95
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Liver microsomal hydroxylation of steroid hormones after establishing an indigenous microflora in germfree rats. Proc Soc Exp Biol Med (1974) 0.79
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med (2007) 12.24
Host-gut microbiota metabolic interactions. Science (2012) 7.73
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Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nat Immunol (2003) 5.87
Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet (2010) 4.65
Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis. Gastroenterology (2003) 2.59
LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets. Nucleic Acids Res (2012) 2.46
A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc Natl Acad Sci U S A (2002) 1.82
Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells. J Biol Chem (2012) 1.76
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger. Proc Natl Acad Sci U S A (2008) 1.74
Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not? Am J Clin Nutr (2005) 1.73
Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression. Cell (2009) 1.68
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Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases. Lancet (2002) 1.50
Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: the Swedish Mammography Cohort. Int J Cancer (2005) 1.49
The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis. Exp Cell Res (2006) 1.46
Therapeutic modulation of microbiota-host metabolic interactions. Sci Transl Med (2012) 1.45
Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4). PLoS One (2010) 1.43
Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc Natl Acad Sci U S A (2009) 1.40
De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. PLoS One (2009) 1.39
Enterococcus faecalis from newborn babies regulate endogenous PPARgamma activity and IL-10 levels in colonic epithelial cells. Proc Natl Acad Sci U S A (2008) 1.38
Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research. J Nutr (2010) 1.33
The Wnt/beta-catenin signaling pathway targets PPARgamma activity in colon cancer cells. Proc Natl Acad Sci U S A (2005) 1.32
Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice. Carcinogenesis (2012) 1.31
Neuropeptide s receptor 1 gene polymorphism is associated with susceptibility to inflammatory bowel disease. Gastroenterology (2007) 1.24
Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1. EMBO J (2002) 1.16
SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. Mol Cancer Ther (2010) 1.14
Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes. EMBO Rep (2004) 1.11
Species identification and profiling of complex microbial communities using shotgun Illumina sequencing of 16S rRNA amplicon sequences. PLoS One (2013) 1.09
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease. Inflamm Bowel Dis (2009) 1.06
Comparative analysis of the complete cag pathogenicity island sequence in four Helicobacter pylori isolates. Gene (2004) 1.04
WAFL, a new protein involved in regulation of early endocytic transport at the intersection of actin and microtubule dynamics. Exp Cell Res (2008) 0.99
Human fecal water content of phenolics: the extent of colonic exposure to aromatic compounds. Free Radic Biol Med (2005) 0.96
The impact of Crohn's disease genes on healthy human gut microbiota: a pilot study. Gut (2013) 0.94
ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways. Am J Physiol Gastrointest Liver Physiol (2013) 0.93
TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet (2013) 0.93
Potential role for the common cystic fibrosis DeltaF508 mutation in Crohn's disease. Inflamm Bowel Dis (2007) 0.91
Abrogated lymphocyte infiltration and lowered CD14 in dextran sulfate induced colitis in mice treated with p65 antisense oligonucleotides. Int J Colorectal Dis (2002) 0.91
Gut microbial communities modulating brain development and function. Gut Microbes (2012) 0.90
Transcriptome signatures in Helicobacter pylori-infected mucosa identifies acidic mammalian chitinase loss as a corpus atrophy marker. BMC Med Genomics (2013) 0.90
DNA-dependent conversion of Oct-1 and Oct-2 into transcriptional repressors by Groucho/TLE. Nucleic Acids Res (2005) 0.89
Analysis of 39 Crohn's disease risk loci in Swedish inflammatory bowel disease patients. Inflamm Bowel Dis (2010) 0.89
ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice. Carcinogenesis (2013) 0.86
Promotion of intestinal tumor formation by inulin is associated with an accumulation of cytosolic beta-catenin in Min mice. Int J Cancer (2003) 0.85
Guidance for substantiating the evidence for beneficial effects of probiotics: impact of probiotics on digestive system metabolism. J Nutr (2010) 0.85
Recombinant adenovirus vector activates and protects human monocyte-derived dendritic cells from apoptosis. Hum Gene Ther (2002) 0.83
The ulcerative colitis marker protein WAFL interacts with accessory proteins in endocytosis. Int J Biol Sci (2010) 0.83
The Women's Health Initiative. What is on trial: nutrition and chronic disease? Or misinterpreted science, media havoc and the sound of silence from peers? Public Health Nutr (2006) 0.82
A constitutively active aryl hydrocarbon receptor causes loss of peritoneal B1 cells. Biochem Biophys Res Commun (2003) 0.81
A CLA's act: feeding away inflammation. Gastroenterology (2004) 0.81
Identification of a new WASP and FKBP-like (WAFL) protein in inflammatory bowel disease: a potential marker gene for ulcerative colitis. Int J Colorectal Dis (2008) 0.81
PPARG binding landscapes in macrophages suggest a genome-wide contribution of PU.1 to divergent PPARG binding in human and mouse. PLoS One (2012) 0.81
The Crohn's associated NOD2 3020InsC frameshift mutation does not confer susceptibility to ankylosing spondylitis. J Rheumatol (2002) 0.81
Helicobacter pylori genome variability in a framework of familial transmission. BMC Microbiol (2007) 0.81
Antiapoptotic effects of dietary antioxidants towards N-nitrosopiperidine and N-nitrosodibutylamine-induced apoptosis in HL-60 and HepG2 cells. J Appl Toxicol (2009) 0.81
Next-generation whole genome sequencing of dengue virus. Methods Mol Biol (2014) 0.80
Selected topics in probiotics and prebiotics: meeting report for the 2004 international scientific association for probiotics and prebiotics. Curr Issues Intest Microbiol (2005) 0.80
The dioxin/aryl hydrocarbon receptor mediates downregulation of osteopontin gene expression in a mouse model of gastric tumourigenesis. Oncogene (2005) 0.80
Functional interaction of CARD15/NOD2 and Crohn's disease-associated TNFalpha polymorphisms. Int J Colorectal Dis (2005) 0.80
Protective effects of isothiocyanates alone or in combination with vitamin C towards N-nitrosodibutylamine or N-nitrosopiperidine-induced oxidative DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. J Appl Toxicol (2008) 0.79
Protective effect of vitamin C towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. Toxicol In Vitro (2007) 0.78
The long and winding road to gut homeostasis. Curr Opin Gastroenterol (2006) 0.78
Induction of apoptosis and reactive oxygen species production by N-nitrosopiperidine and N-nitrosodibutylamine in human leukemia cells. J Appl Toxicol (2008) 0.78
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of HP1352, a putative DNA methyltransferase in Helicobacter pylori. Acta Crystallogr D Biol Crystallogr (2003) 0.77
Inhibition by vitamin C of apoptosis induced by N-nitrosamines in HepG2 and HL-60 cells. J Appl Toxicol (2008) 0.77
Human fecal water modifies adhesion of intestinal bacteria to Caco-2 cells. Nutr Cancer (2005) 0.76
N-Nitrosopiperidine and N-Nitrosodibutylamine induce apoptosis in HepG2 cells via the caspase dependent pathway. Cell Biol Int (2009) 0.76
Probing biomolecular interactions of glutathione transferase M2-2 by using peptide phage display. Chembiochem (2002) 0.75
Solute carriers (SLC) in inflammatory bowel disease: a potential target of probiotics? J Clin Gastroenterol (2008) 0.75
Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. J Appl Toxicol (2006) 0.75
Enterococcus faecalis: a biological marker predicting the emergence of necrotizing enterocolitis. Acta Paediatr (2012) 0.75
Erratum: Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals. Sci Rep (2016) 0.75
Retracted Protective effects of isothiocyanates towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay. J Appl Toxicol (2006) 0.75
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