| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
RNA-guided gene activation by CRISPR-Cas9-based transcription factors.
|
Nat Methods
|
2013
|
4.85
|
|
2
|
Synergistic and tunable human gene activation by combinations of synthetic transcription factors.
|
Nat Methods
|
2013
|
3.26
|
|
3
|
A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage.
|
Nat Mater
|
2007
|
3.06
|
|
4
|
Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention.
|
J Orthop Res
|
2011
|
2.63
|
|
5
|
Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds.
|
Biomaterials
|
2004
|
2.46
|
|
6
|
Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo.
|
Biochem Biophys Res Commun
|
2002
|
2.44
|
|
7
|
Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration.
|
J Biomech
|
2005
|
2.29
|
|
8
|
Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis.
|
Arthritis Rheum
|
2009
|
2.24
|
|
9
|
Multipotent stromal cells derived from the infrapatellar fat pad of the knee.
|
Clin Orthop Relat Res
|
2003
|
2.10
|
|
10
|
The role of mechanical loading in the onset and progression of osteoarthritis.
|
Exerc Sport Sci Rev
|
2005
|
2.09
|
|
11
|
Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype.
|
Nat Protoc
|
2010
|
2.02
|
|
12
|
Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes.
|
Arthritis Rheum
|
2009
|
2.02
|
|
13
|
Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells.
|
Biomaterials
|
2009
|
1.97
|
|
14
|
Viscoelastic properties of human mesenchymally-derived stem cells and primary osteoblasts, chondrocytes, and adipocytes.
|
J Biomech
|
2007
|
1.90
|
|
15
|
Site-specific molecular diffusion in articular cartilage measured using fluorescence recovery after photobleaching.
|
Ann Biomed Eng
|
2003
|
1.85
|
|
16
|
Joint degeneration following closed intraarticular fracture in the mouse knee: a model of posttraumatic arthritis.
|
J Orthop Res
|
2007
|
1.85
|
|
17
|
Biomechanics: cell research and applications for the next decade.
|
Ann Biomed Eng
|
2009
|
1.81
|
|
18
|
The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes.
|
J Orthop Res
|
2004
|
1.77
|
|
19
|
Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice.
|
Arthritis Rheum
|
2010
|
1.75
|
|
20
|
Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis.
|
Am J Physiol Heart Circ Physiol
|
2005
|
1.73
|
|
21
|
A thin-layer model for viscoelastic, stress-relaxation testing of cells using atomic force microscopy: do cell properties reflect metastatic potential?
|
Biophys J
|
2006
|
1.69
|
|
22
|
Clinical and preclinical translation of cell-based therapies using adipose tissue-derived cells.
|
Stem Cell Res Ther
|
2010
|
1.59
|
|
23
|
The biomechanical role of the chondrocyte pericellular matrix in articular cartilage.
|
Acta Biomater
|
2005
|
1.57
|
|
24
|
Differentiation potential of adipose derived adult stem (ADAS) cells.
|
Curr Top Dev Biol
|
2003
|
1.57
|
|
25
|
Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6.
|
Arthritis Rheum
|
2006
|
1.56
|
|
26
|
Zonal changes in the three-dimensional morphology of the chondron under compression: the relationship among cellular, pericellular, and extracellular deformation in articular cartilage.
|
J Biomech
|
2007
|
1.55
|
|
27
|
Effects of transforming growth factor beta1 and dexamethasone on the growth and chondrogenic differentiation of adipose-derived stromal cells.
|
Tissue Eng
|
2003
|
1.54
|
|
28
|
Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis.
|
J Biomech Eng
|
2003
|
1.52
|
|
29
|
The development of posttraumatic arthritis after articular fracture.
|
J Orthop Trauma
|
2006
|
1.51
|
|
30
|
Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions.
|
J Biomed Mater Res B Appl Biomater
|
2004
|
1.51
|
|
31
|
Concise review: Adipose-derived stromal vascular fraction cells and stem cells: let's not get lost in translation.
|
Stem Cells
|
2011
|
1.50
|
|
32
|
Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.
|
Arthritis Res Ther
|
2010
|
1.48
|
|
33
|
Tissue engineering for articular cartilage repair--the state of the art.
|
Eur Cell Mater
|
2013
|
1.48
|
|
34
|
Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide.
|
Biomaterials
|
2006
|
1.48
|
|
35
|
Interleukin-1, tumor necrosis factor-alpha, and transforming growth factor-beta 1 and integrative meniscal repair: influences on meniscal cell proliferation and migration.
|
Arthritis Res Ther
|
2011
|
1.47
|
|
36
|
Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix.
|
Tissue Eng Part A
|
2010
|
1.45
|
|
37
|
Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix.
|
Tissue Eng Part A
|
2009
|
1.44
|
|
38
|
Extended passaging, but not aldehyde dehydrogenase activity, increases the chondrogenic potential of human adipose-derived adult stem cells.
|
J Cell Physiol
|
2006
|
1.42
|
|
39
|
Urea as a passive transport marker for arthritis biomarker studies.
|
Arthritis Rheum
|
2002
|
1.41
|
|
40
|
Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage.
|
J Biomech
|
2005
|
1.41
|
|
41
|
Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling.
|
Tissue Eng
|
2006
|
1.41
|
|
42
|
The mechanical properties of the human hip capsule ligaments.
|
J Arthroplasty
|
2002
|
1.38
|
|
43
|
Influence of oxygen on the proliferation and metabolism of adipose derived adult stem cells.
|
J Cell Physiol
|
2005
|
1.37
|
|
44
|
Developmental and osteoarthritic changes in Col6a1-knockout mice: biomechanics of type VI collagen in the cartilage pericellular matrix.
|
Arthritis Rheum
|
2009
|
1.36
|
|
45
|
Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4.
|
Arthritis Rheum
|
2010
|
1.36
|
|
46
|
Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse.
|
Arthritis Rheum
|
2008
|
1.35
|
|
47
|
Mechanical signals as regulators of stem cell fate.
|
Curr Top Dev Biol
|
2004
|
1.35
|
|
48
|
Human adipose-derived cells: an update on the transition to clinical translation.
|
Regen Med
|
2012
|
1.33
|
|
49
|
TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.
|
Proc Natl Acad Sci U S A
|
2014
|
1.32
|
|
50
|
Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells.
|
Proc Natl Acad Sci U S A
|
2012
|
1.31
|
|
51
|
Spatial mapping of the biomechanical properties of the pericellular matrix of articular cartilage measured in situ via atomic force microscopy.
|
Biophys J
|
2010
|
1.31
|
|
52
|
Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia.
|
J Am Soc Nephrol
|
2005
|
1.30
|
|
53
|
Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise.
|
Arthritis Rheum
|
2012
|
1.29
|
|
54
|
Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice.
|
Arthritis Rheum
|
2013
|
1.25
|
|
55
|
Diffusional anisotropy in collagenous tissues: fluorescence imaging of continuous point photobleaching.
|
Biophys J
|
2006
|
1.24
|
|
56
|
The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model.
|
J Biomech Eng
|
2003
|
1.23
|
|
57
|
Quantitative phase microscopy of articular chondrocyte dynamics by wide-field digital interferometry.
|
J Biomed Opt
|
2010
|
1.21
|
|
58
|
Enhanced integrative repair of the porcine meniscus in vitro by inhibition of interleukin-1 or tumor necrosis factor alpha.
|
Arthritis Rheum
|
2007
|
1.21
|
|
59
|
Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice.
|
Dev Biol
|
2005
|
1.20
|
|
60
|
Circadian oscillation of gene expression in murine calvarial bone.
|
J Bone Miner Res
|
2007
|
1.20
|
|
61
|
Regulation of matrix turnover in meniscal explants: role of mechanical stress, interleukin-1, and nitric oxide.
|
J Appl Physiol (1985)
|
2003
|
1.20
|
|
62
|
Compressive properties of mouse articular cartilage determined in a novel micro-indentation test method and biphasic finite element model.
|
J Biomech Eng
|
2006
|
1.19
|
|
63
|
Differential effects of static and dynamic compression on meniscal cell gene expression.
|
J Orthop Res
|
2003
|
1.19
|
|
64
|
Mechanical regulation of nuclear structure and function.
|
Annu Rev Biomed Eng
|
2012
|
1.19
|
|
65
|
Composite scaffolds for cartilage tissue engineering.
|
Biorheology
|
2008
|
1.18
|
|
66
|
Advanced material strategies for tissue engineering scaffolds.
|
Adv Mater
|
2009
|
1.18
|
|
67
|
Why is obesity associated with osteoarthritis? Insights from mouse models of obesity.
|
Biorheology
|
2008
|
1.17
|
|
68
|
Differentiation of adipose stem cells.
|
Methods Mol Biol
|
2008
|
1.15
|
|
69
|
Conformational mechanics, adsorption, and normal force interactions of lubricin and hyaluronic acid on model surfaces.
|
Langmuir
|
2008
|
1.14
|
|
70
|
Functional properties of cell-seeded three-dimensionally woven poly(epsilon-caprolactone) scaffolds for cartilage tissue engineering.
|
Tissue Eng Part A
|
2010
|
1.14
|
|
71
|
Monolayer cell expansion conditions affect the chondrogenic potential of adipose-derived stem cells.
|
Biotechnol Bioeng
|
2008
|
1.14
|
|
72
|
Pain coping skills training and lifestyle behavioral weight management in patients with knee osteoarthritis: a randomized controlled study.
|
Pain
|
2012
|
1.13
|
|
73
|
Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion.
|
Pain
|
2013
|
1.12
|
|
74
|
In vitro Differentiation Potential of Mesenchymal Stem Cells.
|
Transfus Med Hemother
|
2008
|
1.12
|
|
75
|
Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus.
|
Clin Orthop Relat Res
|
2008
|
1.11
|
|
76
|
The dynamic mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interactions under cyclic compressive loading.
|
J Biomech Eng
|
2008
|
1.11
|
|
77
|
Repair response of the inner and outer regions of the porcine meniscus in vitro.
|
Am J Sports Med
|
2007
|
1.10
|
|
78
|
Diurnal variations in articular cartilage thickness and strain in the human knee.
|
J Biomech
|
2012
|
1.10
|
|
79
|
In situ friction measurement on murine cartilage by atomic force microscopy.
|
J Biomech
|
2007
|
1.09
|
|
80
|
Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry.
|
Biophys J
|
2008
|
1.09
|
|
81
|
The role of F-actin in hypo-osmotically induced cell volume change and calcium signaling in anulus fibrosus cells.
|
Ann Biomed Eng
|
2004
|
1.07
|
|
82
|
Multifunctional hybrid three-dimensionally woven scaffolds for cartilage tissue engineering.
|
Macromol Biosci
|
2010
|
1.06
|
|
83
|
Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage.
|
Arthritis Rheum
|
2002
|
1.06
|
|
84
|
Inhibition of integrative repair of the meniscus following acute exposure to interleukin-1 in vitro.
|
J Orthop Res
|
2008
|
1.06
|
|
85
|
Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus.
|
Biophys J
|
2008
|
1.06
|
|
86
|
Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis.
|
Cell Transplant
|
2012
|
1.05
|
|
87
|
Effects of interleukin-1 on calcium signaling and the increase of filamentous actin in isolated and in situ articular chondrocytes.
|
Arthritis Rheum
|
2006
|
1.05
|
|
88
|
Stem cell-based therapies for osteoarthritis: challenges and opportunities.
|
Curr Opin Rheumatol
|
2013
|
1.04
|
|
89
|
Cartilage viability and catabolism in the intact porcine knee following transarticular impact loading with and without articular fracture.
|
J Orthop Res
|
2010
|
1.04
|
|
90
|
Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis.
|
Arthritis Res Ther
|
2014
|
1.04
|
|
91
|
Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on three-dimensional woven scaffolds.
|
Tissue Eng Part A
|
2010
|
1.04
|
|
92
|
The effects of cyclic mechanical strain and tumor necrosis factor alpha on the response of cells of the meniscus.
|
Osteoarthritis Cartilage
|
2004
|
1.04
|
|
93
|
Synovial fluid concentrations and relative potency of interleukin-1 alpha and beta in cartilage and meniscus degradation.
|
J Orthop Res
|
2013
|
1.03
|
|
94
|
The effects of osmotic stress on the structure and function of the cell nucleus.
|
J Cell Biochem
|
2010
|
1.03
|
|
95
|
Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee.
|
J Orthop Res
|
2002
|
1.03
|
|
96
|
Engineered cartilage using primary chondrocytes cultured in a porous cartilage-derived matrix.
|
Regen Med
|
2011
|
1.03
|
|
97
|
In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(epsilon-caprolactone) scaffolds.
|
Biomaterials
|
2010
|
1.02
|
|
98
|
Diet-induced obesity significantly increases the severity of posttraumatic arthritis in mice.
|
Arthritis Rheum
|
2012
|
1.02
|
|
99
|
Composition and transport properties of human ankle and knee cartilage.
|
J Orthop Res
|
2006
|
1.01
|
|
100
|
The effects of adipokines on cartilage and meniscus catabolism.
|
Connect Tissue Res
|
2011
|
1.01
|
|
101
|
Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche.
|
Biomaterials
|
2011
|
1.01
|
|
102
|
Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration.
|
Biomaterials
|
2013
|
1.01
|
|
103
|
Genipin-crosslinked cartilage-derived matrix as a scaffold for human adipose-derived stem cell chondrogenesis.
|
Tissue Eng Part A
|
2012
|
1.01
|
|
104
|
Age-associated increases in the size of the infrapatellar fat pad in knee osteoarthritis as measured by 3T MRI.
|
J Orthop Res
|
2010
|
1.01
|
|
105
|
Nonlinear osmotic properties of the cell nucleus.
|
Ann Biomed Eng
|
2008
|
1.00
|
|
106
|
Finite element modeling predictions of region-specific cell-matrix mechanics in the meniscus.
|
Biomech Model Mechanobiol
|
2006
|
1.00
|
|
107
|
Immunofluorescence-guided atomic force microscopy to measure the micromechanical properties of the pericellular matrix of porcine articular cartilage.
|
J R Soc Interface
|
2012
|
0.99
|
|
108
|
A mechano-chemical model for the passive swelling response of an isolated chondron under osmotic loading.
|
Biomech Model Mechanobiol
|
2006
|
0.99
|
|
109
|
The effects of crosslinking of scaffolds engineered from cartilage ECM on the chondrogenic differentiation of MSCs.
|
Biomaterials
|
2013
|
0.98
|
|
110
|
Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering.
|
J Biomed Mater Res A
|
2014
|
0.98
|
|
111
|
Hyperosmotically induced volume change and calcium signaling in intervertebral disk cells: the role of the actin cytoskeleton.
|
Biophys J
|
2002
|
0.97
|
|
112
|
High body mass index is associated with increased diurnal strains in the articular cartilage of the knee.
|
Arthritis Rheum
|
2013
|
0.96
|
|
113
|
An axisymmetric boundary integral model for assessing elastic cell properties in the micropipette aspiration contact problem.
|
J Biomech Eng
|
2002
|
0.96
|
|
114
|
Site-specific effects of compression on macromolecular diffusion in articular cartilage.
|
Biophys J
|
2008
|
0.95
|
|
115
|
Depth-dependent anisotropy of the micromechanical properties of the extracellular and pericellular matrices of articular cartilage evaluated via atomic force microscopy.
|
J Biomech
|
2012
|
0.94
|
|
116
|
Measurement of intracellular strain on deformable substrates with texture correlation.
|
J Biomech
|
2006
|
0.94
|
|
117
|
Integrative repair of the meniscus: lessons from in vitro studies.
|
Biorheology
|
2008
|
0.94
|
|
118
|
Nitric oxide synthase and cyclooxygenase interactions in cartilage and meniscus: relationships to joint physiology, arthritis, and tissue repair.
|
Subcell Biochem
|
2007
|
0.94
|
|
119
|
Three-dimensional morphology of the pericellular matrix of intervertebral disc cells in the rat.
|
J Anat
|
2007
|
0.93
|
|
120
|
Mechanical regulation of chondrogenesis.
|
Stem Cell Res Ther
|
2013
|
0.93
|
|
121
|
A biomechanical role for perlecan in the pericellular matrix of articular cartilage.
|
Matrix Biol
|
2012
|
0.93
|
|
122
|
Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells.
|
Tissue Eng Part A
|
2010
|
0.92
|
|
123
|
The inhibition by interleukin 1 of MSC chondrogenesis and the development of biomechanical properties in biomimetic 3D woven PCL scaffolds.
|
Biomaterials
|
2012
|
0.92
|
|
124
|
Chondropathy after meniscal tear or partial meniscectomy in a canine model.
|
J Orthop Res
|
2002
|
0.92
|
|
125
|
Three-dimensional finite element modeling of pericellular matrix and cell mechanics in the nucleus pulposus of the intervertebral disk based on in situ morphology.
|
Biomech Model Mechanobiol
|
2010
|
0.92
|
|
126
|
Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet.
|
Ann Rheum Dis
|
2012
|
0.91
|
|
127
|
Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in osteoblasts.
|
J Clin Invest
|
2002
|
0.91
|
|
128
|
Regional structure-function relationships in mouse aortic valve tissue.
|
J Biomech
|
2010
|
0.91
|
|
129
|
Viscoelastic properties of the aortic valve interstitial cell.
|
J Biomech Eng
|
2009
|
0.91
|
|
130
|
Adipose tissue as a stem cell source for musculoskeletal regeneration.
|
Front Biosci (Schol Ed)
|
2011
|
0.90
|
|
131
|
The relationship of self-reported pain and functional impairment to gait mechanics in overweight and obese persons with knee osteoarthritis.
|
Arch Phys Med Rehabil
|
2009
|
0.90
|
|
132
|
An in vitro system to evaluate the effects of ischemia on survival of cells used for cell therapy.
|
Ann Biomed Eng
|
2007
|
0.90
|
|
133
|
IL-1beta decreases the elastic modulus of human tenocytes.
|
J Appl Physiol (1985)
|
2006
|
0.90
|
|
134
|
The mechanobiology of articular cartilage: bearing the burden of osteoarthritis.
|
Curr Rheumatol Rep
|
2014
|
0.90
|
|
135
|
Racial differences in gait mechanics associated with knee osteoarthritis.
|
Aging Clin Exp Res
|
2009
|
0.90
|
|
136
|
Altered trabecular bone structure and delayed cartilage degeneration in the knees of collagen VI null mice.
|
PLoS One
|
2012
|
0.90
|
|
137
|
An axisymmetric boundary element model for determination of articular cartilage pericellular matrix properties in situ via inverse analysis of chondron deformation.
|
J Biomech Eng
|
2010
|
0.90
|
|
138
|
Biaxial strain effects on cells from the inner and outer regions of the meniscus.
|
Connect Tissue Res
|
2006
|
0.90
|
|
139
|
Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.
|
Proc Natl Acad Sci U S A
|
2014
|
0.89
|
|
140
|
Friction Force Microscopy of Lubricin and Hyaluronic Acid between Hydrophobic and Hydrophilic Surfaces.
|
Soft Matter
|
2009
|
0.89
|
|
141
|
Large deformation finite element analysis of micropipette aspiration to determine the mechanical properties of the chondrocyte.
|
Ann Biomed Eng
|
2005
|
0.88
|
|
142
|
Mechanical properties and gene expression of chondrocytes on micropatterned substrates following dedifferentiation in monolayer.
|
Cell Mol Bioeng
|
2009
|
0.88
|
|
143
|
Application of a Three-Dimensional Poroelastic BEM to Modeling the Biphasic Mechanics of Cell-Matrix Interactions in Articular Cartilage (REVISION).
|
Comput Methods Appl Mech Eng
|
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