Garth J S Cooper

Author PubWeight™ 76.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003 5.32
2 Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J Biol Chem 2005 2.28
3 Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem 2005 1.92
4 Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity. J Biol Chem 2002 1.86
5 Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. Cancer Res 2006 1.75
6 The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells. FEBS J 2006 1.68
7 Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex. J Biol Chem 2006 1.64
8 Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers. Hypertension 2010 1.55
9 Redox status of acute pancreatitis as measured by cyclic voltammetry: initial rodent studies to assess disease severity. Crit Care Med 2008 1.39
10 Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. Nutrition 2008 1.35
11 Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. J Biol Chem 2004 1.33
12 Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism. Proc Natl Acad Sci U S A 2006 1.27
13 Transcriptomic analysis of the cardiac left ventricle in a rodent model of diabetic cardiomyopathy: molecular snapshot of a severe myocardial disease. Physiol Genomics 2006 1.21
14 Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid. Biochem J 2003 1.20
15 Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver. J Immunol Methods 2008 1.13
16 Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. PLoS One 2009 1.10
17 Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1. J Biol Chem 2003 1.10
18 Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats. Proteomics 2008 1.08
19 Randomized controlled crossover study of the effect of a highly beta-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterolemic men. Am J Clin Nutr 2003 1.00
20 The proteome of rodent mesenteric lymph. Am J Physiol Gastrointest Liver Physiol 2008 1.00
21 Altered calcium homeostasis does not explain the contractile deficit of diabetic cardiomyopathy. Diabetes 2008 0.99
22 An altered pattern of circulating apolipoprotein E3 isoforms is implicated in preeclampsia. J Lipid Res 2008 0.97
23 Changes in the mesenteric lymph proteome induced by hemorrhagic shock. Shock 2010 0.97
24 A proteomic approach identifies early pregnancy biomarkers for preeclampsia: novel linkages between a predisposition to preeclampsia and cardiovascular disease. Proteomics 2009 0.96
25 Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. J Mol Biol 2002 0.96
26 Proteomic characterization of human serum proteins associated with the fat-derived hormone adiponectin. Proteomics 2006 0.96
27 The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes. Biochem J 2010 0.94
28 Characterization of proteomic changes in cardiac mitochondria in streptozotocin-diabetic rats using iTRAQ™ isobaric tags. Proteomics Clin Appl 2007 0.94
29 Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum. Proteomics 2004 0.91
30 The proteome of mesenteric lymph during acute pancreatitis and implications for treatment. JOP 2009 0.90
31 Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes 2007 0.90
32 Chronic treatment with growth hormone stimulates adiponectin gene expression in 3T3-L1 adipocytes. FEBS Lett 2004 0.90
33 Identification of novel putative membrane proteins selectively expressed during adipose conversion of 3T3-L1 cells. Biochem Biophys Res Commun 2002 0.90
34 Proteins associated with immunopurified granules from a model pancreatic islet beta-cell system: proteomic snapshot of an endocrine secretory granule. J Proteome Res 2009 0.89
35 Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats. Mol Pharmacol 2006 0.88
36 Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice. Diabetes 2009 0.87
37 Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS). J Chromatogr B Analyt Technol Biomed Life Sci 2007 0.87
38 Reversal of diabetes-evoked changes in mitochondrial protein expression of cardiac left ventricle by treatment with a copper(II)-selective chelator. Proteomics Clin Appl 2007 0.86
39 Thiol reducing compounds prevent human amylin-evoked cytotoxicity. FEBS J 2005 0.85
40 Combined endopeptidase inhibition and adrenomedullin in sheep with experimental heart failure. Hypertension 2002 0.85
41 Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic beta-cells. FEBS J 2006 0.84
42 Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment. Cardiovasc Diabetol 2013 0.83
43 Spontaneous diabetes in hemizygous human amylin transgenic mice that developed neither islet amyloid nor peripheral insulin resistance. Diabetes 2008 0.83
44 No evidence of an effect of alterations in dietary fatty acids on fasting adiponectin over 3 weeks. Obesity (Silver Spring) 2008 0.83
45 Purification, crystallization and preliminary crystallographic analysis of mouse myo-inositol oxygenase. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.82
46 Complex formation equilibria of Cu(II) and Zn(II) with triethylenetetramine and its mono- and di-acetyl metabolites. Dalton Trans 2012 0.82
47 Ethnic disparity of pancreatic cancer in New Zealand. Int J Gastrointest Cancer 2002 0.82
48 Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts. Am J Physiol Cell Physiol 2009 0.81
49 Mice lacking the neuropeptide alpha-calcitonin gene-related peptide are protected against diet-induced obesity. Endocrinology 2010 0.81
50 Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients. Drug Metab Dispos 2006 0.81
51 Proteomic analysis of adipocyte differentiation: Evidence that alpha2 macroglobulin is involved in the adipose conversion of 3T3 L1 preadipocytes. Proteomics 2004 0.81
52 A simple and rapid method for identifying and semi-quantifying peptide hormones in isolated pancreatic islets by direct-tissue matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom 2011 0.81
53 Pharmacokinetics, pharmacodynamics, and metabolism of triethylenetetramine in healthy human participants: an open-label trial. J Clin Pharmacol 2010 0.81
54 Protection of the heart by treatment with a divalent-copper-selective chelator reveals a novel mechanism underlying cardiomyopathy in diabetic rats. Cardiovasc Diabetol 2013 0.81
55 Quantitative proteomic profiling identifies new renal targets of copper(II)-selective chelation in the reversal of diabetic nephropathy in rats. Proteomics 2009 0.81
56 Acute pancreatitis severity is exacerbated by intestinal ischemia-reperfusion conditioned mesenteric lymph. Surgery 2007 0.80
57 A label-free selected reaction monitoring workflow identifies a subset of pregnancy specific glycoproteins as potential predictive markers of early-onset pre-eclampsia. Mol Cell Proteomics 2013 0.80
58 Direct visualisation of peptide hormones in cultured pancreatic islet alpha- and beta-cells by intact-cell mass spectrometry. Rapid Commun Mass Spectrom 2007 0.80
59 Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides. Org Lett 2012 0.79
60 Evidence that alpha-calcitonin gene-related peptide is a neurohormone that controls systemic lipid availability and utilization. Endocrinology 2007 0.78
61 Impaired insulin secretion in perfused pancreases isolated from offspring of female rats fed a low protein whey-based diet. JOP 2008 0.78
62 Aberrant processing of plasma vitronectin and high-molecular-weight kininogen precedes the onset of preeclampsia. Reprod Sci 2009 0.78
63 Pharmacokinetic and pharmacodynamic modeling of a copper-selective chelator (TETA) in healthy adults. J Clin Pharmacol 2009 0.78
64 Illuminating the molecular basis of diabetic arteriopathy: a proteomic comparison of aortic tissue from diabetic and healthy rats. Proteomics 2010 0.78
65 Replacement of the CysA7-CysB7 disulfide bond with a 1,2,3-triazole linker causes unfolding in insulin glargine. Org Biomol Chem 2015 0.78
66 Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine. Biochem J 2008 0.77
67 Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis. HPB (Oxford) 2011 0.77
68 Development and validation of a rapid HPLC method for the simultaneous determination of triethylenetetramine and its two main metabolites in human serum. J Chromatogr B Analyt Technol Biomed Life Sci 2007 0.77
69 Peripherally administered desacetyl alpha-MSH and alpha-MSH both influence postnatal rat growth and associated rat hypothalamic protein expression. Am J Physiol Endocrinol Metab 2006 0.77
70 Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts. Amino Acids 2013 0.77
71 Physicochemical studies on the copper(II) binding by glycated collagen telopeptides. Org Biomol Chem 2015 0.76
72 Combined angiotensin-converting enzyme inhibition and adrenomedullin in an ovine model of heart failure. Clin Sci (Lond) 2002 0.76
73 Plasma clusterin increased prior to small for gestational age (SGA) associated with preeclampsia and decreased prior to SGA in normotensive pregnancies. Reprod Sci 2012 0.76
74 3,12-Diaza-6,9-diazo-nia-2,13-dioxotetra-decane bis-(perchlorate). Acta Crystallogr Sect E Struct Rep Online 2012 0.75
75 Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia. Metallomics 2017 0.75
76 A novel two-chain IGF-II-derived peptide from purified β-cell granules. Growth Horm IGF Res 2010 0.75
77 Synthesis of glycosylated 5-hydroxylysine, an important amino acid present in collagen-like proteins such as adiponectin. Org Biomol Chem 2012 0.75
78 Using mass spectrometry to detect, differentiate, and semiquantitate closely related peptide hormones in complex milieu: measurement of IGF-II and vesiculin. Endocrinology 2014 0.75
79 GSK3 involvement in amylin signaling in isolated rat soleus muscle. Peptides 2004 0.75
80 Synthesis of the IGF-II-like hormone vesiculin using regioselective formation of disulfide bonds. Org Biomol Chem 2013 0.75
81 The redox status of experimental hemorrhagic shock as measured by cyclic voltammetry. Shock 2010 0.75
82 A unique case of neural amyloidoma diagnosed by mass spectrometry of formalin-fixed tissue using a novel preparative technique. Amyloid 2011 0.75