Published in Blood on October 07, 2009
The discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicine. Proc Jpn Acad Ser B Phys Biol Sci (2010) 1.78
CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34. J Leukoc Biol (2013) 1.47
Phenotypic transitions of macrophages orchestrate tissue repair. Am J Pathol (2013) 1.36
Inhibition of plasminogen activator inhibitor-1 restores skeletal muscle regeneration in untreated type 1 diabetic mice. Diabetes (2011) 0.98
c-MET regulates myoblast motility and myocyte fusion during adult skeletal muscle regeneration. PLoS One (2013) 0.96
Regulation of lung injury and fibrosis by p53-mediated changes in urokinase and plasminogen activator inhibitor-1. Am J Pathol (2013) 0.94
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice. Blood (2011) 0.90
Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration. J Immunol (2011) 0.89
Biomaterial-based delivery for skeletal muscle repair. Adv Drug Deliv Rev (2014) 0.85
NF-κB inhibition reveals a novel role for HGF during skeletal muscle repair. Cell Death Dis (2015) 0.83
Cellular players in skeletal muscle regeneration. Biomed Res Int (2014) 0.82
Impaired macrophage and satellite cell infiltration occurs in a muscle-specific fashion following injury in diabetic skeletal muscle. PLoS One (2013) 0.80
The Development of Macrophage-Mediated Cell Therapy to Improve Skeletal Muscle Function after Injury. PLoS One (2015) 0.78
Significance of the urokinase-type plasminogen activator and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models. J Biomed Sci (2016) 0.75
Macrophage plasminogen activator: modulation of enzyme production by anti-inflammatory steroids, mitotic inhibitors, and cyclic nucleotides. Cell (1976) 3.13
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol (1998) 3.05
HGF/SF is present in normal adult skeletal muscle and is capable of activating satellite cells. Dev Biol (1998) 2.65
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. EMBO J (1992) 2.65
Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease. J Biol Chem (2000) 2.47
Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. Am J Pathol (1993) 2.14
Biological activation of pro-HGF (hepatocyte growth factor) by urokinase is controlled by a stoichiometric reaction. J Biol Chem (1995) 2.06
The development of bleomycin-induced pulmonary fibrosis in mice deficient for components of the fibrinolytic system. Am J Pathol (2000) 1.51
Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle. Am J Physiol Cell Physiol (2000) 1.44
Satellite cell activation in stretched skeletal muscle and the role of nitric oxide and hepatocyte growth factor. Am J Physiol Cell Physiol (2006) 1.33
Urokinase receptor deficiency accelerates renal fibrosis in obstructive nephropathy. J Am Soc Nephrol (2003) 1.31
Mechanism of retarded liver regeneration in plasminogen activator-deficient mice: impaired activation of hepatocyte growth factor after Fas-mediated massive hepatic apoptosis. Hepatology (2001) 1.29
Chemotaxis of skeletal muscle satellite cells. Dev Dyn (1997) 1.28
Mechanical stretch induces activation of skeletal muscle satellite cells in vitro. Exp Cell Res (2001) 1.27
HGF is an autocrine growth factor for skeletal muscle satellite cells in vitro. Muscle Nerve (2000) 1.27
Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo. Blood (2001) 1.25
uPA deficiency exacerbates muscular dystrophy in MDX mice. J Cell Biol (2007) 1.22
Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration. J Immunol (2008) 1.17
Role of plasminogen activator in degradation of extracellular matrix protein by live human alveolar macrophages. Am Rev Respir Dis (1988) 1.16
Proteolytic activation of hepatocyte growth factor in response to tissue injury. J Biol Chem (1994) 1.15
Endogenous interferon-gamma is required for efficient skeletal muscle regeneration. Am J Physiol Cell Physiol (2008) 1.15
Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator. Eur J Biochem (1995) 1.14
Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo. Blood (2002) 1.10
Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo. Dev Biol (1996) 1.10
Expression of hepatocyte growth factor in growing and regenerating rat skeletal muscle. Am J Physiol (1993) 1.09
Domain-dependent action of urokinase on smooth muscle cell responses. J Vasc Surg (2004) 1.08
The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism. Am J Pathol (2004) 1.08
Hepatocyte growth factor gene transfer to alveolar septa for effective suppression of lung fibrosis. Mol Ther (2005) 1.08
Mice deficient in plasminogen activator inhibitor-1 have improved skeletal muscle regeneration. Am J Physiol Cell Physiol (2005) 1.07
Active hepatocyte growth factor is present in skeletal muscle extracellular matrix. Muscle Nerve (2004) 1.07
Hepatocyte growth factor plays a dual role in regulating skeletal muscle satellite cell proliferation and differentiation. Biochim Biophys Acta (1998) 1.05
Hepatocyte growth factor is a regulator of monocyte-macrophage function. J Immunol (2001) 1.05
Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator. J Biol Chem (1996) 1.02
Urokinase-type and tissue-type plasminogen activators as growth factors of human fibroblasts. Exp Cell Res (1994) 1.01
Urokinase as a multidomain protein and polyfunctional cell regulator. Biochemistry (Mosc) (2002) 1.01
Plasminogen-mediated activation and release of hepatocyte growth factor from extracellular matrix. Am J Respir Cell Mol Biol (2006) 0.98
Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells. Exp Cell Res (2004) 0.98
Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa. J Biol Chem (2002) 0.98
Hepatocyte growth factor gene transfer into the liver via the portal vein using electroporation attenuates rat liver cirrhosis. Gene Ther (2003) 0.96
Cell invasion is affected by differential expression of the urokinase plasminogen activator/urokinase plasminogen activator receptor system in muscle satellite cells from normal and dystrophic patients. Lab Invest (2001) 0.93
Hepatocyte growth factor gene therapy retards the progression of chronic obstructive nephropathy. Kidney Int (2002) 0.91
Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma. Gene Ther (2004) 0.90
Skeletal muscle injury induces hepatocyte growth factor expression in spleen. Biochem Biophys Res Commun (2002) 0.87
The catalytic domain of endogenous urokinase-type plasminogen activator is required for the mitogenic activity of platelet-derived and basic fibroblast growth factors in human vascular smooth muscle cells. J Cell Sci (2002) 0.85
The urokinase-type plasminogen activator receptor is not required for skeletal muscle inflammation or regeneration. Am J Physiol Regul Integr Comp Physiol (2007) 0.84
Urokinase and tissue-type plasminogen activator are required for the mitogenic and chemotactic effects of bovine fibroblast growth factor and platelet-derived growth factor-BB for vascular smooth muscle cells. J Biol Chem (1997) 0.84
Mactinin treatment promotes wound-healing-associated inflammation in urokinase knockout mice. Wound Repair Regen (2006) 0.83
Growth factor-dependent proliferation and invasion of muscle satellite cells require the cell-associated fibrinolytic system. Biol Chem (2002) 0.81
Hepatocyte growth factor is required for alveologenesis in the neonatal rat. Am J Respir Crit Care Med (2005) 0.79
Cystic fibrosis adult care: consensus conference report. Chest (2004) 2.70
Expression of the reverse tetracycline-transactivator gene causes emphysema-like changes in mice. Am J Respir Cell Mol Biol (2006) 2.46
Selective and specific macrophage ablation is detrimental to wound healing in mice. Am J Pathol (2009) 2.45
Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis. Am J Respir Crit Care Med (2009) 2.15
Macrophage phenotypes during tissue repair. J Leukoc Biol (2013) 1.67
Interleukin-6 treatment reverses apoptosis and blunts susceptibility to intraperitoneal bacterial challenge following hemorrhagic shock. Crit Care Med (2006) 1.52
Dysregulation of monocyte/macrophage phenotype in wounds of diabetic mice. Cytokine (2011) 1.42
Advanced Technologies to Improve Wound Healing: Electrical Stimulation, Vibration Therapy, and Ultrasound-What Is the Evidence? Plast Reconstr Surg (2016) 1.38
Phenotypic transitions of macrophages orchestrate tissue repair. Am J Pathol (2013) 1.36
Plasminogen activator inhibitor-1 impairs alveolar epithelial repair by binding to vitronectin. Am J Respir Cell Mol Biol (2004) 1.34
Different probiotic properties for Lactobacillus fermentum strains isolated from swine and poultry. Anaerobe (2007) 1.33
Neutrophils contribute to muscle injury and impair its resolution after lengthening contractions in mice. J Physiol (2004) 1.28
The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice. J Clin Invest (2010) 1.27
Inducible lung-specific urokinase expression reduces fibrosis and mortality after lung injury in mice. Am J Physiol Lung Cell Mol Physiol (2002) 1.24
Blocking interleukin-1β induces a healing-associated wound macrophage phenotype and improves healing in type 2 diabetes. Diabetes (2013) 1.22
Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis. Am J Respir Cell Mol Biol (2007) 1.20
Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration. J Immunol (2008) 1.17
Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1. Am J Pathol (2003) 1.15
Endogenous interferon-gamma is required for efficient skeletal muscle regeneration. Am J Physiol Cell Physiol (2008) 1.15
Sustained inflammasome activity in macrophages impairs wound healing in type 2 diabetic humans and mice. Diabetes (2013) 1.14
Intracellular signaling specificity in response to uniaxial vs. multiaxial stretch: implications for mechanotransduction. Am J Physiol Cell Physiol (2004) 1.14
Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice. Am J Physiol Cell Physiol (2007) 1.12
Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein. Carcinogenesis (2010) 1.11
Implicating exudate macrophages and Ly-6C(high) monocytes in CCR2-dependent lung fibrosis following gene-targeted alveolar injury. J Immunol (2013) 1.09
The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism. Am J Pathol (2004) 1.08
Muscle inflammatory cells after passive stretches, isometric contractions, and lengthening contractions. J Appl Physiol (1985) (2002) 1.06
COX-2 inhibitor reduces skeletal muscle hypertrophy in mice. Am J Physiol Regul Integr Comp Physiol (2009) 1.05
HSP25 protects skeletal muscle cells against oxidative stress. Free Radic Biol Med (2004) 1.03
Impaired muscle regeneration in ob/ob and db/db mice. ScientificWorldJournal (2011) 1.02
PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury. J Pathol (2012) 1.02
Role of macrophage chemoattractant protein-1 in acute inflammation after lung contusion. Am J Respir Cell Mol Biol (2012) 1.01
Inhalation of urokinase-type plasminogen activator reduces airway remodeling in a murine asthma model. Am J Physiol Lung Cell Mol Physiol (2008) 0.99
Plasminogen-mediated activation and release of hepatocyte growth factor from extracellular matrix. Am J Respir Cell Mol Biol (2006) 0.98
Improved transfection technique for adherent cells using a commercial lipid reagent. Biotechniques (2003) 0.98
Cystic Fibrosis Foundation pulmonary guideline. pharmacologic approaches to prevention and eradication of initial Pseudomonas aeruginosa infection. Ann Am Thorac Soc (2014) 0.97
Functional significance of inflammatory mediators in a murine model of resuscitated hemorrhagic shock. Am J Physiol Heart Circ Physiol (2005) 0.93
Electroporation-mediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusion. J Trauma Acute Care Surg (2012) 0.92
Macrophage activation and skeletal muscle healing following traumatic injury. J Pathol (2014) 0.91
Localization of plasminogen activator activity within normal and injured lungs by in situ zymography. Am J Respir Cell Mol Biol (2004) 0.90
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice. Blood (2011) 0.90
Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration. J Immunol (2011) 0.89
Host susceptibility to gram-negative pneumonia after lung contusion. J Trauma Acute Care Surg (2012) 0.88
Prevention of trauma/hemorrhagic shock-induced lung apoptosis by IL-6-mediated activation of Stat3. Clin Transl Sci (2009) 0.87
Expression of rumen microbial fibrolytic enzyme genes in probiotic Lactobacillus reuteri. Appl Environ Microbiol (2005) 0.87
Antagonistic activity against Salmonella infection in vitro and in vivo for two Lactobacillus strains from swine and poultry. Int J Food Microbiol (2005) 0.86
Prevention of trauma and hemorrhagic shock-mediated liver apoptosis by activation of stat3alpha. Int J Clin Exp Med (2008) 0.86
Increased phospholipase A2 and lyso-phosphatidylcholine levels are associated with surfactant dysfunction in lung contusion injury in mice. Surgery (2012) 0.85
The urokinase-type plasminogen activator receptor is not required for skeletal muscle inflammation or regeneration. Am J Physiol Regul Integr Comp Physiol (2007) 0.84
A plasminogen activator inhibitor-1 promoter polymorphism and idiopathic interstitial pneumonia. Mol Med (2003) 0.83
Essential role for platelets in organ injury and inflammation in resuscitated hemorrhagic shock. Shock (2006) 0.82
IL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammation. PLoS One (2011) 0.82
Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling. J Biol Chem (2011) 0.81
Role of pulmonary artery reactivity and nitric oxide in injury and inflammation following lung contusion. Shock (2013) 0.81
Mechanical strain increases gene transfer to skeletal muscle cells. J Biomech (2006) 0.81
Effect of Echinacea purpurea L. on oxidative status and meat quality in Arbor Acres broilers. J Sci Food Agric (2012) 0.80
The relative efficacy of different strain combinations of lactic acid bacteria in the reduction of populations of Salmonella enterica Typhimurium in the livers and spleens of mice. FEMS Immunol Med Microbiol (2011) 0.80
Alveolar macrophage depletion increases the severity of acute inflammation following nonlethal unilateral lung contusion in mice. J Trauma Acute Care Surg (2014) 0.80
Coexpression of rumen microbial beta-glucanase and xylanase genes in Lactobacillus reuteri. Appl Microbiol Biotechnol (2007) 0.80
Assessing macrophage phenotype during tissue repair. Methods Mol Biol (2013) 0.80
The protective role of MnTBAP in oxidant-mediated injury and inflammation in a rat model of lung contusion. Surgery (2013) 0.80
Enterocin T, a novel class IIa bacteriocin produced by Enterococcus sp. 812. Arch Microbiol (2013) 0.79
Effect of Pleurotus eryngii stalk residue on the oxidative status and meat quality of broiler chickens. J Agric Food Chem (2012) 0.79
Clinical implications of macrolide therapy in chronic sinopulmonary diseases. Curr Pharm Des (2004) 0.79
Expression of Lactobacillus reuteri Pg4 collagen-binding protein gene in Lactobacillus casei ATCC 393 increases its adhesion ability to Caco-2 cells. J Agric Food Chem (2010) 0.78
Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine. Evid Based Complement Alternat Med (2013) 0.78
Interleukin 10 overexpression alters survival in the setting of gram-negative pneumonia following lung contusion. Shock (2014) 0.78
Display of Fibrobacter succinogenes β-glucanase on the cell surface of Lactobacillus reuteri. J Agric Food Chem (2011) 0.77
Development of a murine model of blunt hepatic trauma. Comp Med (2013) 0.77
Increase of the adhesion ability and display of a rumen fungal xylanase on the cell surface of Lactobacillus casei by using a listerial cell-wall-anchoring protein. J Sci Food Agric (2013) 0.77
Shedding light on impaired efferocytosis and nonresolving inflammation. Circ Res (2013) 0.77
Starch characteristics and their influences on in vitro and pig prececal starch digestion. J Agric Food Chem (2011) 0.77
Porcine lactoferrin expression in transgenic rice and its effects as a feed additive on early weaned piglets. J Agric Food Chem (2010) 0.76
Cell specific control of coagulation and fibrinolysis within the lung. Thromb Haemost (2004) 0.76
Direct cloning of a xylanase gene from the mixed genomic DNA of rumen fungi and its expression in intestinal Lactobacillus reuteri. FEMS Microbiol Lett (2005) 0.76
Use of specific primers based on the 16S-23S internal transcribed spacer (ITS) region for the screening Bifidobacterium adolescentis in yogurt products and human stool samples. Anaerobe (2008) 0.75
Three-Dimensional in Vivo Kinematics of the Shoulder during Humeral Elevation. J Appl Biomech (1998) 0.75