Published in Crit Care Med on March 01, 2006
Prevention of trauma and hemorrhagic shock-mediated liver apoptosis by activation of stat3alpha. Int J Clin Exp Med (2008) 0.86
The prevention and treatment of sepsis: is interleukin-6 a drug target or a drug? Crit Care Med (2006) 0.83
Protection of intestinal injury during heat stroke in mice by interleukin-6 pretreatment. J Physiol (2015) 0.80
Restoration of lung surfactant protein D by IL-6 protects against secondary pneumonia following hemorrhagic shock. J Infect (2013) 0.79
Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury. Respir Res (2017) 0.75
Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Mol Cell Biol (2002) 2.24
Targeting Stat3 in cancer therapy. Anticancer Drugs (2005) 2.13
Single nucleotide polymorphisms in genes for 2'-5'-oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection. J Infect Dis (2005) 2.11
Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor. Cancer Res (2003) 1.73
Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor. Blood (2011) 1.69
Stat3 activation links a C/EBPδ to myostatin pathway to stimulate loss of muscle mass. Cell Metab (2013) 1.49
Intra-abdominal activation of a local inflammatory response within the human muscularis externa during laparotomy. Ann Surg (2003) 1.42
Chemical probes that competitively and selectively inhibit Stat3 activation. PLoS One (2009) 1.37
Plasminogen activator inhibitor-1 impairs alveolar epithelial repair by binding to vitronectin. Am J Respir Cell Mol Biol (2004) 1.34
Different probiotic properties for Lactobacillus fermentum strains isolated from swine and poultry. Anaerobe (2007) 1.33
Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol (2004) 1.33
G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis. Cancer Res (2004) 1.29
Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif. J Biol Chem (2004) 1.28
Targeting Stat3 with G-quartet oligodeoxynucleotides in human cancer cells. DNA Cell Biol (2003) 1.23
Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways. Blood (2002) 1.18
Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer. Mol Cancer Ther (2006) 1.16
Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. PLoS One (2012) 1.14
Targeting transcription factors for cancer therapy. Curr Pharm Des (2005) 1.10
Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end. J Biol Chem (2007) 1.08
DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A. J Cell Sci (2005) 1.05
Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy. Elife (2013) 1.02
Role of macrophage chemoattractant protein-1 in acute inflammation after lung contusion. Am J Respir Cell Mol Biol (2012) 1.01
Induction of IL-6 within the rodent intestinal muscularis after intestinal surgical stress. Surgery (2005) 1.01
STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells (2014) 0.99
FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report. Blood (2012) 0.97
Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha. Mol Cell Biol (2004) 0.96
Rational drug design of G-quartet DNA as anti-cancer agents. Curr Pharm Des (2005) 0.96
Cross-talk between retinoic acid and STAT3 signaling pathways in acute promyelocytic leukemia. Leuk Lymphoma (2003) 0.95
Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3. PLoS One (2008) 0.93
Urokinase-type plasminogen activator increases hepatocyte growth factor activity required for skeletal muscle regeneration. Blood (2009) 0.93
Functional significance of inflammatory mediators in a murine model of resuscitated hemorrhagic shock. Am J Physiol Heart Circ Physiol (2005) 0.93
Electroporation-mediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusion. J Trauma Acute Care Surg (2012) 0.92
Substance P causes seizures in neurocysticercosis. PLoS Pathog (2012) 0.91
Substance P is required for the pathogenesis of EMCV infection in mice. Int J Clin Exp Med (2009) 0.90
Alternative patterns of transcription and translation of the ribosomal protein L32 mRNA in somatic and spermatogenic cells in mice. Exp Cell Res (2003) 0.89
Increased expression of type-1 fimbriae by nonpathogenic Escherichia coli 83972 results in an increased capacity for catheter adherence and bacterial interference. J Infect Dis (2008) 0.89
Host susceptibility to gram-negative pneumonia after lung contusion. J Trauma Acute Care Surg (2012) 0.88
Prevention of trauma/hemorrhagic shock-induced lung apoptosis by IL-6-mediated activation of Stat3. Clin Transl Sci (2009) 0.87
Expression of rumen microbial fibrolytic enzyme genes in probiotic Lactobacillus reuteri. Appl Environ Microbiol (2005) 0.87
Antagonistic activity against Salmonella infection in vitro and in vivo for two Lactobacillus strains from swine and poultry. Int J Food Microbiol (2005) 0.86
Prevention of trauma and hemorrhagic shock-mediated liver apoptosis by activation of stat3alpha. Int J Clin Exp Med (2008) 0.86
Conditional overexpression of Stat3alpha in differentiating myeloid cells results in neutrophil expansion and induces a distinct, antiapoptotic and pro-oncogenic gene expression pattern. J Leukoc Biol (2007) 0.86
The effect of recombinant factor VIIa on noncoagulopathic pigs with grade V liver injuries. J Am Coll Surg (2003) 0.86
Increased phospholipase A2 and lyso-phosphatidylcholine levels are associated with surfactant dysfunction in lung contusion injury in mice. Surgery (2012) 0.85
Synthetic and biological studies of phaeosphaerides. J Org Chem (2014) 0.84
T40214/PEI complex: a potent therapeutics for prostate cancer that targets STAT3 signaling. Prostate (2008) 0.84
Substance P is responsible for physiological alterations such as increased chloride ion secretion and glucose malabsorption in cryptosporidiosis. Infect Immun (2006) 0.83
Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}. Blood (2009) 0.83
Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744. J Immunol (2006) 0.83
IL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammation. PLoS One (2011) 0.82
Amplification of the proinflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine. J Surg Res (2003) 0.82
A nitric oxide scavenger protects against pulmonary inflammation following hemorrhagic shock. Shock (2002) 0.82
Essential role for platelets in organ injury and inflammation in resuscitated hemorrhagic shock. Shock (2006) 0.82
Substance P signaling contributes to granuloma formation in Taenia crassiceps infection, a murine model of cysticercosis. J Biomed Biotechnol (2010) 0.82
Role of pulmonary artery reactivity and nitric oxide in injury and inflammation following lung contusion. Shock (2013) 0.81
Nanoscale surface modification favors benign biofilm formation and impedes adherence by pathogens. Nanomedicine (2011) 0.81
The relative efficacy of different strain combinations of lactic acid bacteria in the reduction of populations of Salmonella enterica Typhimurium in the livers and spleens of mice. FEMS Immunol Med Microbiol (2011) 0.80
Alveolar macrophage depletion increases the severity of acute inflammation following nonlethal unilateral lung contusion in mice. J Trauma Acute Care Surg (2014) 0.80
Effect of Echinacea purpurea L. on oxidative status and meat quality in Arbor Acres broilers. J Sci Food Agric (2012) 0.80
A novel role of microRNA146b in promoting mammary alveolar progenitor cell maintenance. J Cell Sci (2013) 0.80
Essential role for the dimerization domain of NuMA-RARalpha in its oncogenic activities and localization to NuMA sites within the nucleus. Oncogene (2003) 0.80
Coexpression of rumen microbial beta-glucanase and xylanase genes in Lactobacillus reuteri. Appl Microbiol Biotechnol (2007) 0.80
Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell level. Mol Biol Cell (2007) 0.80
The protective role of MnTBAP in oxidant-mediated injury and inflammation in a rat model of lung contusion. Surgery (2013) 0.80
Enterocin T, a novel class IIa bacteriocin produced by Enterococcus sp. 812. Arch Microbiol (2013) 0.79
Effect of Pleurotus eryngii stalk residue on the oxidative status and meat quality of broiler chickens. J Agric Food Chem (2012) 0.79
Lethal human neutropenic entercolitis caused by Clostridium chauvoei in the United States: tip of the iceberg? J Infect (2011) 0.79
Severe pulmonary involvement in a case attributed to domestically acquired Seoul hantavirus in the United States. Clin Infect Dis (2011) 0.79
Expression of Lactobacillus reuteri Pg4 collagen-binding protein gene in Lactobacillus casei ATCC 393 increases its adhesion ability to Caco-2 cells. J Agric Food Chem (2010) 0.78
Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine. Evid Based Complement Alternat Med (2013) 0.78
Interleukin 10 overexpression alters survival in the setting of gram-negative pneumonia following lung contusion. Shock (2014) 0.78
SH2 domain binding to phosphopeptide ligands: potential for drug targeting. Front Biosci (Landmark Ed) (2009) 0.78
Substance P receptor antagonism for treatment of cryptosporidiosis in immunosuppressed mice. J Parasitol (2008) 0.78
Modulation of the unfolded protein response during hepatocyte and cardiomyocyte apoptosis in trauma/hemorrhagic shock. Sci Rep (2013) 0.77
Development of a murine model of blunt hepatic trauma. Comp Med (2013) 0.77
Increase of the adhesion ability and display of a rumen fungal xylanase on the cell surface of Lactobacillus casei by using a listerial cell-wall-anchoring protein. J Sci Food Agric (2013) 0.77
Display of Fibrobacter succinogenes β-glucanase on the cell surface of Lactobacillus reuteri. J Agric Food Chem (2011) 0.77
Starch characteristics and their influences on in vitro and pig prececal starch digestion. J Agric Food Chem (2011) 0.77
Nanoparticle delivery of inhibitory signal transducer and activator of transcription 3 G-quartet oligonucleotides blocks tumor growth in HMGA1 transgenic model of T-cell leukemia. Leuk Lymphoma (2013) 0.77
Increased apoptosis of peripheral blood neutrophils is associated with reduced incidence of infection in trauma patients with hemorrhagic shock. J Infect (2012) 0.76
Porcine lactoferrin expression in transgenic rice and its effects as a feed additive on early weaned piglets. J Agric Food Chem (2010) 0.76
Direct cloning of a xylanase gene from the mixed genomic DNA of rumen fungi and its expression in intestinal Lactobacillus reuteri. FEMS Microbiol Lett (2005) 0.76
Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†. PLoS One (2016) 0.75
Use of specific primers based on the 16S-23S internal transcribed spacer (ITS) region for the screening Bifidobacterium adolescentis in yogurt products and human stool samples. Anaerobe (2008) 0.75
Intracranial tuberculomas in adults: a report of twelve consecutive patients in Houston, Texas. Scand J Infect Dis (2011) 0.75
Successful ceftriaxone therapy of endocarditis due to penicillin non-susceptible viridans streptococci. J Infect (2006) 0.75
Requirements for NF-kappaB activation in hemorrhagic shock. Arch Orthop Trauma Surg (2002) 0.75