Plasmid-mediated quinolone resistance: a multifaceted threat.

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Published in Clin Microbiol Rev on October 01, 2009

Authors

Jacob Strahilevitz1, George A Jacoby, David C Hooper, Ari Robicsek

Author Affiliations

1: Department of Clinical Microbiology and Infectious Diseases, Hadassah Ein-Kerem, Jerusalem 91120, Israel. jstrahilevitz@hadassah.org.il

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Plasmid-mediated quinolone resistance in non-Typhi serotypes of Salmonella enterica. Clin Infect Dis (2006) 3.66

Abrupt emergence of a single dominant multidrug-resistant strain of Escherichia coli. J Infect Dis (2013) 3.56

Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States. Antimicrob Agents Chemother (2004) 3.54

Detection of toxigenic Clostridium difficile in stool samples by real-time polymerase chain reaction for the diagnosis of C. difficile-associated diarrhea. Clin Infect Dis (2007) 3.24

Interaction of plasmid and host quinolone resistance. J Antimicrob Chemother (2003) 3.13

Interaction of the plasmid-encoded quinolone resistance protein QnrA with Escherichia coli topoisomerase IV. Antimicrob Agents Chemother (2005) 2.90

Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period. Antimicrob Agents Chemother (2008) 2.70

Veteran's affairs hospital discharge databases coded serious bacterial infections accurately. J Clin Epidemiol (2006) 2.51

blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513. Antimicrob Agents Chemother (2002) 2.47

New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. Antimicrob Agents Chemother (2009) 2.32

Molecular epidemiological analysis of Escherichia coli sequence type ST131 (O25:H4) and blaCTX-M-15 among extended-spectrum-β-lactamase-producing E. coli from the United States, 2000 to 2009. Antimicrob Agents Chemother (2012) 2.17

Objective surveillance definitions for ventilator-associated pneumonia. Crit Care Med (2012) 2.17

Electronic health record-based detection of risk factors for Clostridium difficile infection relapse. Infect Control Hosp Epidemiol (2013) 2.08

Fluoroquinolones and the risk for methicillin-resistant Staphylococcus aureus in hospitalized patients. Emerg Infect Dis (2003) 2.06

Comparison of Escherichia coli ST131 pulsotypes, by epidemiologic traits, 1967-2009. Emerg Infect Dis (2012) 2.05

Case records of the Massachusetts General Hospital. Case 3-2015. A 60-year-old woman with abdominal pain, dyspnea, and diplopia. N Engl J Med (2015) 1.97

Performance of the BD GeneOhm methicillin-resistant Staphylococcus aureus test before and during high-volume clinical use. J Clin Microbiol (2007) 1.97

Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus. J Bacteriol (2003) 1.81

Does my patient have Clostridium difficile infection? Ann Intern Med (2009) 1.80

oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae. Antimicrob Agents Chemother (2009) 1.77

Discontinuation of contact precautions for methicillin-resistant staphylococcus aureus: a randomized controlled trial comparing passive and active screening with culture and polymerase chain reaction. Clin Infect Dis (2013) 1.57

Enhanced identification of postoperative infections among inpatients. Emerg Infect Dis (2004) 1.56

Reporting catheter-associated urinary tract infections: denominator matters. Infect Control Hosp Epidemiol (2011) 1.50

NorB, an efflux pump in Staphylococcus aureus strain MW2, contributes to bacterial fitness in abscesses. J Bacteriol (2008) 1.47

Recurrent meningitis of unknown aetiology. Lancet (2004) 1.43

A recA-LexA-dependent pathway mediates ciprofloxacin-induced fibronectin binding in Staphylococcus aureus. J Biol Chem (2003) 1.41

Molecular epidemiology of Escherichia coli sequence type 131 and Its H30 and H30-Rx subclones among extended-spectrum-β-lactamase-positive and -negative E. coli clinical isolates from the Chicago Region, 2007 to 2010. Antimicrob Agents Chemother (2013) 1.40

5 Million Lives Campaign. Case study: an MRSA intervention at Evanston Northwestern Healthcare. Jt Comm J Qual Patient Saf (2007) 1.40

NorC, a new efflux pump regulated by MgrA of Staphylococcus aureus. Antimicrob Agents Chemother (2006) 1.37

Changes in qnr prevalence and fluoroquinolone resistance in clinical isolates of Klebsiella pneumoniae and Enterobacter spp. collected from 1990 to 2005. Antimicrob Agents Chemother (2007) 1.37

Chromogenic media vs real-time PCR for nasal surveillance of methicillin-resistant Staphylococcus aureus: impact on detection of MRSA-positive persons. Am J Clin Pathol (2009) 1.35

Dual targeting of DNA gyrase and topoisomerase IV: target interactions of garenoxacin (BMS-284756, T-3811ME), a new desfluoroquinolone. Antimicrob Agents Chemother (2002) 1.34

Human Salmonella and concurrent decreased susceptibility to quinolones and extended-spectrum cephalosporins. Emerg Infect Dis (2007) 1.32

Activity of and resistance to moxifloxacin in Staphylococcus aureus. Antimicrob Agents Chemother (2003) 1.30

Mechanistic and structural analysis of aminoglycoside N-acetyltransferase AAC(6')-Ib and its bifunctional, fluoroquinolone-active AAC(6')-Ib-cr variant. Biochemistry (2008) 1.27

Detection of postoperative surgical-site infections: comparison of health plan-based surveillance with hospital-based programs. Infect Control Hosp Epidemiol (2003) 1.27

Citrobacter spp. as a source of qnrB Alleles. Antimicrob Agents Chemother (2011) 1.26

The transcriptional regulators NorG and MgrA modulate resistance to both quinolones and beta-lactams in Staphylococcus aureus. J Bacteriol (2007) 1.26

vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium. Antimicrob Agents Chemother (2010) 1.25

Transferable quinolone resistance in Vibrio cholerae. Antimicrob Agents Chemother (2009) 1.22

Temporal appearance of plasmid-mediated quinolone resistance genes. Antimicrob Agents Chemother (2009) 1.17

Regional occurrence of plasmid-mediated SHV-7, an extended-spectrum beta-lactamase, in Enterobacter cloacae in Philadelphia Teaching Hospitals. Clin Infect Dis (2002) 1.17

SOS regulation of qnrB expression. Antimicrob Agents Chemother (2008) 1.16

Enhanced surgical site infection surveillance following hysterectomy, vascular, and colorectal surgery. Infect Control Hosp Epidemiol (2012) 1.14

Structure of QnrB1, a plasmid-mediated fluoroquinolone resistance factor. J Biol Chem (2011) 1.13

Quinolone resistance due to reduced target enzyme expression. J Bacteriol (2003) 1.13

CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 28-2015. A 32-Year-Old Man with Fever, Headache, and Myalgias after Traveling from Liberia. N Engl J Med (2015) 1.13

Predictors and molecular epidemiology of community-onset extended-spectrum β-lactamase-producing Escherichia coli infection in a Midwestern community. Infect Control Hosp Epidemiol (2013) 1.12

Emergency department visit rates for abscess versus other skin infections during the emergence of community-associated methicillin-resistant Staphylococcus aureus, 1997-2007. Clin Infect Dis (2012) 1.12

Epidemiology of dermatitis and skin infections in United States physicians' offices, 1993-2005. Clin Infect Dis (2009) 1.10

Diffusion-weighted imaging of fungal cerebral infection. AJNR Am J Neuroradiol (2005) 1.10

NorA functions as a multidrug efflux protein in both cytoplasmic membrane vesicles and reconstituted proteoliposomes. J Bacteriol (2002) 1.10

Use of Medicare diagnosis and procedure codes to improve detection of surgical site infections following hip arthroplasty, knee arthroplasty, and vascular surgery. Infect Control Hosp Epidemiol (2011) 1.09

Activities of newer quinolones against Escherichia coli and Klebsiella pneumoniae containing the plasmid-mediated quinolone resistance determinant qnr. Antimicrob Agents Chemother (2004) 1.08

Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus. J Bacteriol (2008) 1.07

Implementation of a universal admission surveillance and decolonization program for methicillin-resistant staphylococcus aureus (MRSA) reduces the number of MRSA and total number of S. aureus isolates reported by the clinical laboratory. J Clin Microbiol (2009) 1.07

Laboratory testing for Clostridium difficile infection: light at the end of the tunnel. Am J Clin Pathol (2011) 1.07

Natural history of colonization with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE): a systematic review. BMC Infect Dis (2014) 1.04

Significant impact of terminal room cleaning with bleach on reducing nosocomial Clostridium difficile. Am J Infect Control (2010) 1.03

Dual targeting of topoisomerase IV and gyrase to reduce mutant selection: direct testing of the paradigm by using WCK-1734, a new fluoroquinolone, and ciprofloxacin. Antimicrob Agents Chemother (2005) 1.03

Antibiotic dosing before primary hip and knee replacement as a pay-for-performance measure. J Bone Joint Surg Am (2007) 1.02

Phosphorylation of MgrA and its effect on expression of the NorA and NorB efflux pumps of Staphylococcus aureus. J Bacteriol (2010) 1.02

Impact of laboratory-reported urine culture colony counts on the diagnosis and treatment of urinary tract infection for hospitalized patients. Am J Clin Pathol (2012) 1.01

Topoisomerase targeting with and resistance to gemifloxacin in Staphylococcus aureus. Antimicrob Agents Chemother (2003) 0.98

Management of a multidrug-resistant Acinetobacter baumannii outbreak in an intensive care unit using novel environmental disinfection: a 38-month report. Am J Infect Control (2009) 0.98

Impact of ciprofloxacin exposure on Staphylococcus aureus genomic alterations linked with emergence of rifampin resistance. Antimicrob Agents Chemother (2011) 0.97

Resource burden associated with contact precautions for methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus: the patient access managers' perspective. Infect Control Hosp Epidemiol (2012) 0.94

Staphylococcus aureus NorD, a putative efflux pump coregulated with the Opp1 oligopeptide permease, contributes selectively to fitness in vivo. J Bacteriol (2012) 0.94

The electronic medical record as a tool for infection surveillance: successful automation of device-days. Am J Infect Control (2009) 0.93