Published in Cardiovasc Res on October 14, 2009
Mechanical Stretch Inhibits MicroRNA499 via p53 to Regulate Calcineurin-A Expression in Rat Cardiomyocytes. PLoS One (2016) 1.38
Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling. Proc Natl Acad Sci U S A (2013) 1.12
Pumping Ca2+ up H+ gradients: a Ca2(+)-H+ exchanger without a membrane. J Physiol (2014) 0.93
Sarcolemmal localisation of Na+/H+ exchange and Na+-HCO3- co-transport influences the spatial regulation of intracellular pH in rat ventricular myocytes. J Physiol (2013) 0.91
Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydrase. PLoS One (2011) 0.87
Endogenous L-Carnosine Level in Diabetes Rat Cardiac Muscle. Evid Based Complement Alternat Med (2016) 0.75
Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res (2005) 4.79
Fibroblast network in rabbit sinoatrial node: structural and functional identification of homogeneous and heterogeneous cell coupling. Circ Res (2004) 2.90
Regulation of tumor pH and the role of carbonic anhydrase 9. Cancer Metastasis Rev (2007) 2.56
Generation of histo-anatomically representative models of the individual heart: tools and application. Philos Trans A Math Phys Eng Sci (2009) 2.37
Axial stretch of rat single ventricular cardiomyocytes causes an acute and transient increase in Ca2+ spark rate. Circ Res (2009) 2.35
Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study. Heart Rhythm (2009) 2.05
Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function. Am J Physiol Heart Circ Physiol (2009) 1.84
Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation. J Electrocardiol (2005) 1.75
Image-based models of cardiac structure in health and disease. Wiley Interdiscip Rev Syst Biol Med (2010) 1.67
Three-dimensional models of individual cardiac histoanatomy: tools and challenges. Ann N Y Acad Sci (2006) 1.66
Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking. J Physiol (2004) 1.59
Spatially and temporally distinct expression of fibroblast connexins after sheep ventricular infarction. Cardiovasc Res (2004) 1.57
The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths. J Biol Chem (2009) 1.53
Myocardial ischemia lowers precordial thump efficacy: an inquiry into mechanisms using three-dimensional simulations. Heart Rhythm (2006) 1.51
Systems biology and the virtual physiological human. Mol Syst Biol (2009) 1.48
Experimental generation and computational modeling of intracellular pH gradients in cardiac myocytes. Biophys J (2005) 1.41
Palette of fluorinated voltage-sensitive hemicyanine dyes. Proc Natl Acad Sci U S A (2012) 1.41
Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths. J Biol Chem (2008) 1.40
Functional characterization of human NBC4 as an electrogenic Na+-HCO cotransporter (NBCe2). Am J Physiol Cell Physiol (2002) 1.39
A vision and strategy for the virtual physiological human in 2010 and beyond. Philos Trans A Math Phys Eng Sci (2010) 1.33
Pip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice. Mol Ther (2011) 1.32
Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium. Nat Protoc (2006) 1.30
Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clin Cancer Res (2012) 1.30
Force-length relations in isolated intact cardiomyocytes subjected to dynamic changes in mechanical load. Am J Physiol Heart Circ Physiol (2006) 1.26
Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing. Br J Pharmacol (2012) 1.26
Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers. Circ Res (2012) 1.24
Ca2+-mobility in the sarcoplasmic reticulum of ventricular myocytes is low. Biophys J (2008) 1.18
Single-sensor system for spatially resolved, continuous, and multiparametric optical mapping of cardiac tissue. Heart Rhythm (2011) 1.18
Structural and functional coupling of cardiac myocytes and fibroblasts. Adv Cardiol (2006) 1.18
Functional diversity of electrogenic Na+-HCO3- cotransport in ventricular myocytes from rat, rabbit and guinea pig. J Physiol (2004) 1.17
The effect of microgrooved culture substrates on calcium cycling of cardiac myocytes derived from human induced pluripotent stem cells. Biomaterials (2012) 1.16
Histo-anatomical structure of the living isolated rat heart in two contraction states assessed by diffusion tensor MRI. Prog Biophys Mol Biol (2012) 1.15
Heterogeneous cell coupling in the heart: an electrophysiological role for fibroblasts. Circ Res (2003) 1.15
Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling. Proc Natl Acad Sci U S A (2013) 1.12
Cardiac myocyte-nonmyocyte electrotonic coupling: implications for ventricular arrhythmogenesis. Heart Rhythm (2006) 1.11
Microstructured cocultures of cardiac myocytes and fibroblasts: a two-dimensional in vitro model of cardiac tissue. Microsc Microanal (2005) 1.11
CELLULAR OPEN RESOURCE (COR): current status and future directions. Philos Trans A Math Phys Eng Sci (2009) 1.11
Intracellular proton mobility and buffering power in cardiac ventricular myocytes from rat, rabbit, and guinea pig. Am J Physiol Heart Circ Physiol (2003) 1.10
Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain. J Biol Chem (2011) 1.07
Cardiac mechano-electric feedback: past, present, and prospect. Prog Biophys Mol Biol (2003) 1.06
Effect of stretch-activated channels on defibrillation efficacy. Heart Rhythm (2004) 1.06
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors. Cancer Res (2011) 1.05
Modelling intracellular H(+) ion diffusion. Prog Biophys Mol Biol (2003) 1.05
Relationship between intracellular pH and proton mobility in rat and guinea-pig ventricular myocytes. J Physiol (2005) 1.04
Axial stretch enhances sarcoplasmic reticulum Ca2+ leak and cellular Ca2+ reuptake in guinea pig ventricular myocytes: experiments and models. Prog Biophys Mol Biol (2008) 1.04
Cardiosphere-derived cells improve function in the infarcted rat heart for at least 16 weeks--an MRI study. PLoS One (2011) 1.02
Role of the 293b-sensitive, slowly activating delayed rectifier potassium current, i(Ks), in pacemaker activity of rabbit isolated sino-atrial node cells. Cardiovasc Res (2002) 1.00
Modulatory effect of calmodulin-dependent kinase II (CaMKII) on sarcoplasmic reticulum Ca2+ handling and interval-force relations: a modelling study. Philos Trans A Math Phys Eng Sci (2006) 1.00
One-dimensional rabbit sinoatrial node models: benefits and limitations. J Cardiovasc Electrophysiol (2003) 1.00
Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths. J Biol Chem (2011) 0.99
Acute pH-dependent regulation of AE2-mediated anion exchange involves discrete local surfaces of the NH2-terminal cytoplasmic domain. J Biol Chem (2004) 0.98
In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy. PLoS One (2012) 0.98
Combining wet and dry research: experience with model development for cardiac mechano-electric structure-function studies. Cardiovasc Res (2013) 0.97
Putative re-entrant loop 1 of AE2 transmembrane domain has a major role in acute regulation of anion exchange by pH. J Biol Chem (2008) 0.97
Induction of ventricular arrhythmias following mechanical impact: a simulation study in 3D. J Mol Histol (2004) 0.97
Extracellular acidification elicits spatially and temporally distinct Ca2+ signals. Curr Biol (2008) 0.96
Species- and preparation-dependence of stretch effects on sino-atrial node pacemaking. Ann N Y Acad Sci (2005) 0.96
Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia. J Cell Physiol (2013) 0.96
Tissue slices from adult mammalian hearts as a model for pharmacological drug testing. Cell Physiol Biochem (2009) 0.95
The chemistry, physiology and pathology of pH in cancer. Philos Trans R Soc Lond B Biol Sci (2014) 0.94
Fast measurement of sarcomere length and cell orientation in Langendorff-perfused hearts using remote focusing microscopy. Circ Res (2013) 0.93
Temporal pixel multiplexing for simultaneous high-speed, high-resolution imaging. Nat Methods (2010) 0.93
Myocardial tissue slices: organotypic pseudo-2D models for cardiac research & development. Future Cardiol (2009) 0.93
Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors. J Med Chem (2005) 0.93
In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy. J Gene Med (2010) 0.93
Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics. Proc Natl Acad Sci U S A (2013) 0.92
Fibroblast-myocyte connections in the heart. Heart Rhythm (2011) 0.92
Assessment of contractility in intact ventricular cardiomyocytes using the dimensionless 'Frank-Starling Gain' index. Pflugers Arch (2011) 0.92
pH-Dependence of extrinsic and intrinsic H(+)-ion mobility in the rat ventricular myocyte, investigated using flash photolysis of a caged-H(+) compound. Biophys J (2006) 0.92
Progressive changes in T₁, T₂ and left-ventricular histo-architecture in the fixed and embedded rat heart. NMR Biomed (2010) 0.92
H+ ion activation and inactivation of the ventricular gap junction: a basis for spatial regulation of intracellular pH. Circ Res (2007) 0.91
Sarcolemmal localisation of Na+/H+ exchange and Na+-HCO3- co-transport influences the spatial regulation of intracellular pH in rat ventricular myocytes. J Physiol (2013) 0.91
3D visualization of cardiac anatomical MRI data with para-cellular resolution. Conf Proc IEEE Eng Med Biol Soc (2007) 0.91
Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX. Eur J Pharmacol (2011) 0.91
Molecular candidates for cardiac stretch-activated ion channels. Glob Cardiol Sci Pract (2014) 0.90
Modeling calcium waves in cardiac myocytes: importance of calcium diffusion. Front Biosci (Landmark Ed) (2010) 0.90
The virtual physiological human: tools and applications I. Philos Trans A Math Phys Eng Sci (2009) 0.89
Hydrogen ion dynamics in human red blood cells. J Physiol (2010) 0.89
Integration of acid-base and electrolyte disorders. N Engl J Med (2015) 0.89
Spatial regulation of intracellular pH in the ventricular myocyte. Ann N Y Acad Sci (2005) 0.89
Dimensionality in cardiac modelling. Prog Biophys Mol Biol (2005) 0.89
H⁺-activated Na⁺ influx in the ventricular myocyte couples Ca²⁺-signalling to intracellular pH. J Mol Cell Cardiol (2013) 0.88
Mechano-sensitivity of cardiac pacemaker function: pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity. Prog Biophys Mol Biol (2012) 0.88
Influence of pH on Ca²⁺ current and its control of electrical and Ca²⁺ signaling in ventricular myocytes. J Gen Physiol (2011) 0.88
Systems biology of the heart: hype or hope? Ann N Y Acad Sci (2011) 0.87
The virtual physiological human: computer simulation for integrative biomedicine I. Philos Trans A Math Phys Eng Sci (2010) 0.87
Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion. BJU Int (2008) 0.85
In situ optical mapping of voltage and calcium in the heart. PLoS One (2012) 0.85
Cardiac cellular heterogeneity and remodelling. Cardiovasc Res (2004) 0.85
Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin. PLoS One (2012) 0.85
Proton permeation through the myocardial gap junction. Circ Res (2003) 0.85
Mechanical modulation of the transverse tubular system of ventricular cardiomyocytes. Prog Biophys Mol Biol (2012) 0.85
Axial tubule junctions control rapid calcium signaling in atria. J Clin Invest (2016) 0.83