Published in BMC Genomics on October 27, 2009
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J (2013) 2.70
Development of a dehalogenase-based protein fusion tag capable of rapid, selective and covalent attachment to customizable ligands. Curr Chem Genomics (2012) 1.06
HaloTag: a novel reporter gene for positron emission tomography. Am J Transl Res (2011) 1.04
HaloTag, a Platform Technology for Protein Analysis. Curr Chem Genomics (2012) 0.95
Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight. Epigenetics (2015) 0.87
The HaloTag: Improving Soluble Expression and Applications in Protein Functional Analysis. Curr Chem Genomics (2012) 0.83
HaloTag as a reporter gene: positron emission tomography imaging with (64)Cu-labeled second generation HaloTag ligands. Am J Transl Res (2013) 0.81
HaloTag technology: a versatile platform for biomedical applications. Bioconjug Chem (2015) 0.80
A quantitative assay to study protein:DNA interactions, discover transcriptional regulators of gene expression, and identify novel anti-tumor agents. J Vis Exp (2013) 0.79
A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta. Nucleic Acids Res (2010) 0.78
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Genome-wide mapping of in vivo protein-DNA interactions. Science (2007) 64.92
Genome-wide location and function of DNA binding proteins. Science (2000) 31.25
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science (2008) 16.48
An extended transcriptional network for pluripotency of embryonic stem cells. Cell (2008) 14.64
Control of pancreas and liver gene expression by HNF transcription factors. Science (2004) 12.05
Divergent transcription from active promoters. Science (2008) 11.03
Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol (2001) 10.69
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proc Natl Acad Sci U S A (1986) 10.41
Function and regulation of CREB family transcription factors in the nervous system. Neuron (2002) 7.99
Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment. Nat Methods (2004) 7.93
ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin immunoprecipitation experiments. Genomics (2004) 7.21
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature (2005) 7.14
In vivo cross-linking and immunoprecipitation for studying dynamic Protein:DNA associations in a chromatin environment. Methods (1999) 6.76
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci U S A (2005) 6.26
Identification and functional analysis of human transcriptional promoters. Genome Res (2003) 6.23
Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell (2004) 6.08
HaloTag: a novel protein labeling technology for cell imaging and protein analysis. ACS Chem Biol (2008) 6.00
An abundance of bidirectional promoters in the human genome. Genome Res (2004) 5.90
Single-molecule analysis of dynein processivity and stepping behavior. Cell (2006) 5.63
Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science (2008) 5.48
Mapping protein-DNA interactions in vivo with formaldehyde: evidence that histone H4 is retained on a highly transcribed gene. Cell (1988) 5.08
Mapping of transcription factor binding regions in mammalian cells by ChIP: comparison of array- and sequencing-based technologies. Genome Res (2007) 4.59
TORCs: transducers of regulated CREB activity. Mol Cell (2003) 4.42
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res (2008) 4.08
Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome. Genome Res (2005) 3.85
Bidirectional gene organization: a common architectural feature of the human genome. Cell (2002) 3.47
GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis. Proc Natl Acad Sci U S A (2002) 3.41
Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods (2002) 3.37
Arabidopsis CLV3 peptide directly binds CLV1 ectodomain. Science (2008) 3.31
High-resolution ChIP-chip analysis reveals that the Drosophila MSL complex selectively identifies active genes on the male X chromosome. Genes Dev (2006) 3.30
Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Mol Cell (2003) 3.23
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Cell (2005) 3.22
Comparison of sample preparation methods for ChIP-chip assays. Biotechniques (2006) 2.89
CREB binds to multiple loci on human chromosome 22. Mol Cell Biol (2004) 2.28
Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. EMBO J (2007) 2.07
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies. Nat Methods (2008) 2.02
Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin. Proc Natl Acad Sci U S A (2009) 1.99
The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex. Proc Natl Acad Sci U S A (1994) 1.95
In vivo protein-protein and protein-DNA crosslinking for genomewide binding microarray. Methods (2003) 1.92
Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome. Genome Res (2007) 1.82
Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms. EMBO J (2007) 1.67
Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation. Proc Natl Acad Sci U S A (1990) 1.60
Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB. Proc Natl Acad Sci U S A (2001) 1.51
Two distinct forms of active transcription factor CREB (cAMP response element binding protein). Proc Natl Acad Sci U S A (1990) 1.47
Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB. Mol Cell Biol (2001) 1.46
Genomic approaches that aid in the identification of transcription factor target genes. Exp Biol Med (Maywood) (2004) 1.41
The specificity of protein-DNA crosslinking by formaldehyde: in vitro and in drosophila embryos. Nucleic Acids Res (2000) 1.37
Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein. Mol Cell Biol (2000) 1.11
Spatial separation and bidirectional trafficking of proteins using a multi-functional reporter. BMC Cell Biol (2008) 1.04
Exploration of human ORFeome: high-throughput preparation of ORF clones and efficient characterization of their protein products. DNA Res (2008) 0.98
Genome-wide analysis of protein-DNA interactions in living cells. Genome Biol (2001) 0.92
Glutamine rich and basic region/leucine zipper (bZIP) domains stabilize cAMP-response element-binding protein (CREB) binding to chromatin. J Biol Chem (2005) 0.88
Identification of ubiquitin ligase activity of RBCK1 and its inhibition by splice variant RBCK2 and protein kinase Cbeta. J Biol Chem (2008) 0.87
Methods for detection of protein-protein and protein-DNA interactions using HaloTag. Methods Mol Biol (2008) 0.86
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
HaloTag: a novel protein labeling technology for cell imaging and protein analysis. ACS Chem Biol (2008) 6.00
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res (2008) 4.08
Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome. Genome Res (2005) 3.85
Direct isolation and identification of promoters in the human genome. Genome Res (2005) 3.68
Diverse and specific gene expression responses to stresses in cultured human cells. Mol Biol Cell (2004) 3.02
Nonemergency PCI at hospitals with or without on-site cardiac surgery. N Engl J Med (2013) 2.98
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J (2013) 2.70
Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue. PLoS Genet (2011) 2.68
Transcription factor binding and modified histones in human bidirectional promoters. Genome Res (2007) 2.40
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors. Cell (2013) 2.34
Functional analysis of transcription factor binding sites in human promoters. Genome Biol (2012) 2.12
The HaloTag: a novel technology for cell imaging and protein analysis. Methods Mol Biol (2007) 1.90
Serum response factor binding sites differ in three human cell types. Genome Res (2007) 1.85
The ets-related transcription factor GABP directs bidirectional transcription. PLoS Genet (2007) 1.67
Sequence features that drive human promoter function and tissue specificity. Genome Res (2010) 1.40
HaloTag7: a genetically engineered tag that enhances bacterial expression of soluble proteins and improves protein purification. Protein Expr Purif (2009) 1.27
Engineered luciferases for molecular sensing in living cells. Curr Opin Biotechnol (2009) 1.12
Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122. J Biol Chem (2011) 1.11
Development of a dehalogenase-based protein fusion tag capable of rapid, selective and covalent attachment to customizable ligands. Curr Chem Genomics (2012) 1.06
HaloTag-based purification of functional human kinases from mammalian cells. Protein Expr Purif (2010) 1.05
Luciferase Reporter Assay System for Deciphering GPCR Pathways. Curr Chem Genomics (2010) 1.05
Examining the complexity of human RNA polymerase complexes using HaloTag technology coupled to label free quantitative proteomics. J Proteome Res (2012) 1.02
Don't you forget about me: considering acute rhabdomyolysis in ED patients with cocaine ingestion. Can Fam Physician (2012) 0.98
Mass spectrometry compatible surfactant for optimized in-gel protein digestion. Anal Chem (2013) 0.88
Electrophilic aromatic substituted luciferins as bioluminescent probes for glutathione S-transferase assays. Chem Commun (Camb) (2006) 0.87
Methods for detection of protein-protein and protein-DNA interactions using HaloTag. Methods Mol Biol (2008) 0.86
The recognition and treatment of vertebral fractures in males with chronic obstructive pulmonary disease. Respir Med (2008) 0.83
Pediatric rehabilitation: 1. Common medical conditions in children with disabilities. PM R (2010) 0.81
A high-throughput 1,536-well luminescence assay for glutathione S-transferase activity. Assay Drug Dev Technol (2010) 0.80
HaloTag technology for specific and covalent labeling of fusion proteins. Methods Mol Biol (2015) 0.80
Identification of a Functional In Vivo p53 Response Element in the Coding Sequence of the Xeroderma Pigmentosum Group C Gene. Genes Cancer (2012) 0.79
Isolation of intracellular protein--DNA complexes using HaloCHIP, an antibody-free alternative to chromatin immunoprecipitation. Methods Mol Biol (2013) 0.78
Authors' response: Re: my Concerns about the American Academy of Pediatrics clinical report on "Motor delays: early identification and evaluation". Pediatrics (2013) 0.75
Should I stay or should I go?: toxic alcohol case in the emergency department. Can Fam Physician (2009) 0.75
When clinicians and a parent disagree on the extent of medical care. J Dev Behav Pediatr (2009) 0.75
When clinicians and a parent disagree on the extent of medical care. J Dev Behav Pediatr (2010) 0.75
Clinical parity in emergency mental health. Psychiatr Serv (2002) 0.75
Pediatric rehabilitation: 4. Prescribing assistive technology to promote community integration. PM R (2010) 0.75
Pediatric rehabilitation: 5. Transitioning teens with disabilities into adulthood. PM R (2010) 0.75
So, who's complaining about the food? Ombudsman perspectives on "the dining experience" in North Carolina's nursing homes. N C Med J (2005) 0.75
Use of an electronic information system to identify adverse events resulting in an emergency department visit. Qual Saf Health Care (2010) 0.75
Pediatric rehabilitation: 3. Facilitating family-centered treatment decisions. PM R (2010) 0.75