| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
|
Nature
|
2012
|
9.89
|
|
2
|
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
|
Nat Genet
|
2012
|
7.61
|
|
3
|
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.
|
Nature
|
2011
|
6.39
|
|
4
|
Lin28 promotes transformation and is associated with advanced human malignancies.
|
Nat Genet
|
2009
|
6.35
|
|
5
|
Analysis of the coding genome of diffuse large B-cell lymphoma.
|
Nat Genet
|
2011
|
6.06
|
|
6
|
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.
|
N Engl J Med
|
2014
|
5.37
|
|
7
|
CREST maps somatic structural variation in cancer genomes with base-pair resolution.
|
Nat Methods
|
2011
|
5.34
|
|
8
|
Inactivating mutations of acetyltransferase genes in B-cell lymphoma.
|
Nature
|
2011
|
5.20
|
|
9
|
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer.
|
Science
|
2012
|
4.92
|
|
10
|
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia.
|
Lancet Oncol
|
2009
|
4.89
|
|
11
|
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.
|
Cancer Cell
|
2012
|
4.41
|
|
12
|
Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.
|
J Exp Med
|
2011
|
4.37
|
|
13
|
Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia.
|
Nat Genet
|
2009
|
4.35
|
|
14
|
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome.
|
Blood
|
2010
|
4.00
|
|
15
|
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia.
|
Blood
|
2010
|
3.66
|
|
16
|
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas.
|
Nat Genet
|
2013
|
3.51
|
|
17
|
Acute lymphoblastic leukaemia.
|
Lancet
|
2013
|
3.44
|
|
18
|
The genomic landscape of hypodiploid acute lymphoblastic leukemia.
|
Nat Genet
|
2013
|
3.43
|
|
19
|
Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.
|
Blood
|
2011
|
3.40
|
|
20
|
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia.
|
Blood
|
2009
|
2.86
|
|
21
|
Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?
|
Blood
|
2012
|
2.82
|
|
22
|
Acute Lymphoblastic Leukemia in Children.
|
N Engl J Med
|
2015
|
2.33
|
|
23
|
The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.
|
Immunity
|
2012
|
2.15
|
|
24
|
Mutations in CBL occur frequently in juvenile myelomonocytic leukemia.
|
Blood
|
2009
|
2.15
|
|
25
|
Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study.
|
Blood
|
2012
|
2.09
|
|
26
|
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia.
|
Proc Natl Acad Sci U S A
|
2009
|
1.92
|
|
27
|
Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia.
|
Blood
|
2008
|
1.89
|
|
28
|
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
|
J Natl Cancer Inst
|
2013
|
1.81
|
|
29
|
Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia.
|
Blood
|
2012
|
1.78
|
|
30
|
Cell of origin strongly influences genetic selection in a mouse model of T-ALL.
|
Blood
|
2011
|
1.78
|
|
31
|
Tyrosine kinase inhibitor therapy induces remission in a patient with refractory EBF1-PDGFRB-positive acute lymphoblastic leukemia.
|
J Clin Oncol
|
2013
|
1.73
|
|
32
|
Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia.
|
Blood
|
2012
|
1.66
|
|
33
|
Tissue plasminogen activator -7351C/T enhancer polymorphism is a risk factor for lacunar stroke.
|
Stroke
|
2004
|
1.55
|
|
34
|
Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project.
|
Blood
|
2012
|
1.47
|
|
35
|
Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia.
|
Blood
|
2010
|
1.47
|
|
36
|
The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.
|
Blood
|
2011
|
1.45
|
|
37
|
Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse.
|
Nat Genet
|
2013
|
1.45
|
|
38
|
Mannose-binding lectin deficiency does not increase the prevalence of Helicobacter pylori seropositivity.
|
Eur J Gastroenterol Hepatol
|
2007
|
1.38
|
|
39
|
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells.
|
Nat Med
|
2011
|
1.34
|
|
40
|
Outcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease.
|
J Clin Oncol
|
2014
|
1.31
|
|
41
|
Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome.
|
J Exp Med
|
2013
|
1.26
|
|
42
|
Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia.
|
Clin Cancer Res
|
2013
|
1.23
|
|
43
|
Replicative potential of human natural killer cells.
|
Br J Haematol
|
2009
|
1.19
|
|
44
|
Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia.
|
J Clin Invest
|
2013
|
1.19
|
|
45
|
Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice.
|
Blood
|
2011
|
1.16
|
|
46
|
Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia.
|
J Clin Oncol
|
2010
|
1.14
|
|
47
|
Human gastrointestinal neoplasia-associated myofibroblasts can develop from bone marrow-derived cells following allogeneic stem cell transplantation.
|
Stem Cells
|
2009
|
1.14
|
|
48
|
Rare allelic forms of PRDM9 associated with childhood leukemogenesis.
|
Genome Res
|
2012
|
1.09
|
|
49
|
Interleukins-1, -4, -6, -10, tumor necrosis factor, transforming growth factor-beta, FAS, and mannose-binding protein C gene polymorphisms in Australian women: Risk of preterm birth.
|
Am J Obstet Gynecol
|
2004
|
1.09
|
|
50
|
Improving outcomes for high-risk ALL: translating new discoveries into clinical care.
|
Pediatr Blood Cancer
|
2011
|
1.05
|
|
51
|
Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression.
|
Blood
|
2011
|
1.00
|
|
52
|
Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.
|
Haematologica
|
2013
|
0.99
|
|
53
|
LOHAS: loss-of-heterozygosity analysis suite.
|
Genet Epidemiol
|
2011
|
0.99
|
|
54
|
Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential.
|
J Exp Med
|
2014
|
0.99
|
|
55
|
Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group.
|
Blood
|
2013
|
0.99
|
|
56
|
Defective K-Ras oncoproteins overcome impaired effector activation to initiate leukemia in vivo.
|
Blood
|
2013
|
0.95
|
|
57
|
Advances in the genetics of high-risk childhood B-progenitor acute lymphoblastic leukemia and juvenile myelomonocytic leukemia: implications for therapy.
|
Clin Cancer Res
|
2012
|
0.93
|
|
58
|
Donor mannose-binding lectin deficiency increases the likelihood of clinically significant infection after liver transplantation.
|
Clin Infect Dis
|
2009
|
0.90
|
|
59
|
How new advances in genetic analysis are influencing the understanding and treatment of childhood acute leukemia.
|
Curr Opin Pediatr
|
2011
|
0.85
|
|
60
|
The role of TET2 in hematologic neoplasms.
|
Cancer Cell
|
2011
|
0.83
|
|
61
|
Mutations of NOTCH1, FBXW7, and prognosis in T-lineage acute lymphoblastic leukemia.
|
Haematologica
|
2009
|
0.82
|
|
62
|
Genetic variation and the risk of acute lymphoblastic leukemia.
|
Leuk Res
|
2010
|
0.80
|
|
63
|
Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study.
|
BMC Pregnancy Childbirth
|
2005
|
0.80
|
|
64
|
Generation of human acute lymphoblastic leukemia xenografts for use in oncology drug discovery.
|
Curr Protoc Pharmacol
|
2015
|
0.77
|
|
65
|
Genetic alterations targeting lymphoid development in acute lymphoblastic leukemia.
|
Curr Top Dev Biol
|
2011
|
0.77
|
|
66
|
Tumor-specific genetic lesions and their influence on therapy in pediatric acute lymphoblastic leukemia.
|
Hematology Am Soc Hematol Educ Program
|
2006
|
0.77
|
|
67
|
Mannose-binding lectin and liver transplantation.
|
Gastroenterology
|
2005
|
0.76
|
|
68
|
Mannose-binding lectin and gastric cancer.
|
Int J Cancer
|
2007
|
0.75
|
|
69
|
PHF6 mutations in T-lineage acute lymphoblastic leukemia.
|
Pediatr Blood Cancer
|
2010
|
0.75
|