Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.

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Published in Cancer Cell on August 14, 2012

Authors

Kathryn G Roberts1, Ryan D Morin, Jinghui Zhang, Martin Hirst, Yongjun Zhao, Xiaoping Su, Shann-Ching Chen, Debbie Payne-Turner, Michelle L Churchman, Richard C Harvey, Xiang Chen, Corynn Kasap, Chunhua Yan, Jared Becksfort, Richard P Finney, David T Teachey, Shannon L Maude, Kane Tse, Richard Moore, Steven Jones, Karen Mungall, Inanc Birol, Michael N Edmonson, Ying Hu, Kenneth E Buetow, I-Ming Chen, William L Carroll, Lei Wei, Jing Ma, Maria Kleppe, Ross L Levine, Guillermo Garcia-Manero, Eric Larsen, Neil P Shah, Meenakshi Devidas, Gregory Reaman, Malcolm Smith, Steven W Paugh, William E Evans, Stephan A Grupp, Sima Jeha, Ching-Hon Pui, Daniela S Gerhard, James R Downing, Cheryl L Willman, Mignon Loh, Stephen P Hunger, Marco A Marra, Charles G Mullighan

Author Affiliations

1: Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Associated clinical trials:

Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia | NCT00137111

Dexamethasone Compared With Prednisone During Induction Therapy and MTX With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia | NCT00075725

Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia | NCT00549848

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