Evidence of kinetic control of ligand binding and staged product release in MurA (enolpyruvyl UDP-GlcNAc synthase)-catalyzed reactions .

The structural biology of enzymes involved in natural product glycosylation. Nat Prod Rep (2012) 1.07

Functional consequence of covalent reaction of phosphoenolpyruvate with UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA). J Biol Chem (2012) 0.86

Microbial engineering for the production of advanced biofuels. Nature (2012) 3.60

Crystal structure of human XLF: a twist in nonhomologous DNA end-joining. Mol Cell (2007) 1.73

Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4. Mol Cell Biol (2009) 1.43

Transition-state analysis of the DNA repair enzyme MutY. J Am Chem Soc (2008) 1.29

Engineering dynamic pathway regulation using stress-response promoters. Nat Biotechnol (2013) 1.27

Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive. J Mol Biol (2003) 1.24

Vimentin exposed on activated platelets and platelet microparticles localizes vitronectin and plasminogen activator inhibitor complexes on their surface. J Biol Chem (2001) 1.21

Spectral tuning of azobenzene photoswitches for biological applications. Angew Chem Int Ed Engl (2009) 1.19

Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants. J Biol Chem (2007) 1.07

The structure of DdrB from Deinococcus: a new fold for single-stranded DNA binding proteins. Nucleic Acids Res (2010) 1.07

Transition state analysis of acid-catalyzed dAMP hydrolysis. J Am Chem Soc (2007) 1.02

Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function. J Med Chem (2007) 1.02

UDP-N-acetylmuramic acid (UDP-MurNAc) is a potent inhibitor of MurA (enolpyruvyl-UDP-GlcNAc synthase). Biochemistry (2005) 1.00

Central metabolic responses to the overproduction of fatty acids in Escherichia coli based on 13C-metabolic flux analysis. Biotechnol Bioeng (2014) 0.97

Adenine release is fast in MutY-catalyzed hydrolysis of G:A and 8-Oxo-G:A DNA mismatches. J Biol Chem (2003) 0.96

Development of Synechocystis sp. PCC 6803 as a phototrophic cell factory. Mar Drugs (2013) 0.95

Incorporation of vitronectin into fibrin clots. Evidence for a binding interaction between vitronectin and gamma A/gamma' fibrinogen. J Biol Chem (2001) 0.94

Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate. BMC Struct Biol (2007) 0.93

Structural and biochemical characterization of SrcA, a multi-cargo type III secretion chaperone in Salmonella required for pathogenic association with a host. PLoS Pathog (2010) 0.93

Measuring dynamics in weakly structured regions of proteins using microfluidics-enabled subsecond H/D exchange mass spectrometry. Anal Chem (2012) 0.91

Probing the transition states of four glucoside hydrolyses with 13C kinetic isotope effects measured at natural abundance by NMR spectroscopy. J Am Chem Soc (2004) 0.89

Negative feedback regulation of fatty acid production based on a malonyl-CoA sensor-actuator. ACS Synth Biol (2014) 0.87

A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem (2006) 0.86

Identification of the catalytic residues of AroA (Enolpyruvylshikimate 3-phosphate synthase) using partitioning analysis. Biochemistry (2003) 0.84

Crystallization and preliminary X-ray diffraction analysis of the human XRCC4-XLF complex. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.84

Structure of an asymmetric ternary protein complex provides insight for membrane interaction. Structure (2012) 0.83

Structural characterization of a novel Chlamydia pneumoniae type III secretion-associated protein, Cpn0803. PLoS One (2012) 0.83

Synthesis of 3,3'-bis(sulfonato)-4,4'-bis(chloroacetamido)azobenzene and cysteine cross-linking for photo-control of protein conformation and activity. Nat Protoc (2007) 0.83

Structural and kinetic characterization of the LPS biosynthetic enzyme D-alpha,beta-D-heptose-1,7-bisphosphate phosphatase (GmhB) from Escherichia coli. Biochemistry (2010) 0.83

Catalytic residues and an electrostatic sandwich that promote enolpyruvyl shikimate 3-phosphate synthase (AroA) catalysis. Biochemistry (2009) 0.81

Lyme disease enolpyruvyl-UDP-GlcNAc synthase: fosfomycin-resistant MurA from Borrelia burgdorferi, a fosfomycin-sensitive mutant, and the catalytic role of the active site Asp. Biochemistry (2011) 0.81

Magnetic "fishing" assay to screen small-molecule mixtures for modulators of protein-protein interactions. Anal Chem (2010) 0.81

Crystal structure of the DdrB/ssDNA complex from Deinococcus radiodurans reveals a DNA binding surface involving higher-order oligomeric states. Nucleic Acids Res (2013) 0.81

Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence. J Med Chem (2013) 0.80

Transition state analysis of enolpyruvylshikimate 3-phosphate (EPSP) synthase (AroA)-catalyzed EPSP hydrolysis. J Am Chem Soc (2012) 0.78

sGAL: a computational method for finding surface exposed sites in proteins suitable for Cys-mediated cross-linking. Bioinformatics (2006) 0.78

The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand. BMC Biochem (2013) 0.77

Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor. BMC Struct Biol (2009) 0.77

Structural-functional studies of Burkholderia cenocepacia D-glycero-β-D-manno-heptose 7-phosphate kinase (HldA) and characterization of inhibitors with antibiotic adjuvant and antivirulence properties. J Med Chem (2013) 0.77

Transition state analysis of acid-catalyzed hydrolysis of an enol ether, enolpyruvylshikimate 3-phosphate (EPSP). J Am Chem Soc (2012) 0.77

Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions. BMC Struct Biol (2011) 0.76

Phosphate analogues as probes of the catalytic mechanisms of MurA and AroA, two carboxyvinyl transferases. Biochemistry (2006) 0.76

Nonenzymatic breakdown of the tetrahedral (alpha-carboxyketal phosphate) intermediates of MurA and AroA, two carboxyvinyl transferases. Protonation of different functional groups controls the rate and fate of breakdown. J Am Chem Soc (2003) 0.76

Delineation of key XRCC4/Ligase IV interfaces for targeted disruption of non-homologous end joining DNA repair. Proteins (2013) 0.76

Binding of heparin to plasma proteins and endothelial surfaces is inhibited by covalent linkage to antithrombin. Thromb Haemost (2004) 0.76

Correction: A 99mTc-Labelled Tetrazine for Bioorthogonal Chemistry. Synthesis and Biodistribution Studies with Small Molecule trans-Cyclooctene Derivatives. PLoS One (2017) 0.75

Bridging the gap between systems biology and synthetic biology. Front Microbiol (2013) 0.75

Potent Inhibition of 3-Deoxy-d-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic. Biochemistry (2016) 0.75

Evaluation of the calmodulin-SOX9 interaction by "magnetic fishing" coupled to mass spectrometry. Chembiochem (2014) 0.75

Structural effects of a covalent linkage between antithrombin and heparin: covalent N-terminus attachment of heparin enhances the maintenance of antithrombin's activated state. J Biochem (2006) 0.75

[Effect of early intestinal dripping of jianpi tongli Chinese herbs on serum level IL-2, sIL-2R and IL-12 in patients with gastric cancer after operation]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2005) 0.75

Implications of protonation and substituent effects for C-O and O-P bond cleavage in phosphate monoesters. J Am Chem Soc (2006) 0.75

Enolpyruvyl activation by enolpyruvylshikimate-3-phosphate synthase. Biochemistry (2007) 0.75