Published in Development on December 01, 2009
NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J (2010) 2.01
Primordial germ cells in mice. Cold Spring Harb Perspect Biol (2012) 1.23
TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol (2011) 1.20
Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype. Cancer Res (2012) 1.13
Rebuilding pluripotency from primordial germ cells. Stem Cell Reports (2013) 1.09
Epigenetic reprogramming in the germline: towards the ground state of the epigenome. Philos Trans R Soc Lond B Biol Sci (2011) 0.99
Switching on pluripotency: a perspective on the biological requirement of Nanog. Philos Trans R Soc Lond B Biol Sci (2011) 0.97
The role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell states. Curr Opin Genet Dev (2013) 0.93
Germ cell specification and pluripotency in mammals: a perspective from early embryogenesis. Reprod Med Biol (2014) 0.93
Fishing pluripotency mechanisms in vivo. Int J Biol Sci (2011) 0.92
Alkaline phosphatase in stem cells. Stem Cells Int (2015) 0.90
A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis. PLoS One (2010) 0.89
Implication of DNA demethylation and bivalent histone modification for selective gene regulation in mouse primordial germ cells. PLoS One (2012) 0.89
NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers. Nature (2016) 0.88
Regulation of embryonic stem cell pluripotency by heat shock protein 90. Stem Cells (2012) 0.87
Uncovering gene regulatory networks during mouse fetal germ cell development. Biol Reprod (2010) 0.86
Synthetic strategies for studying embryonic development. Chem Biol (2010) 0.84
FGF, Insulin, and SMAD Signaling Cooperate for Avian Primordial Germ Cell Self-Renewal. Stem Cell Reports (2015) 0.83
Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells. Biol Open (2014) 0.81
Specification and epigenetic programming of the human germ line. Nat Rev Genet (2016) 0.80
Human short-latency auditory responses obtained by cross-correlation. Electroencephalogr Clin Neurophysiol (1987) 0.79
Bone morphogenetic protein 4 mediates human embryonic germ cell derivation. Stem Cells Dev (2010) 0.79
The ligand binding domain of GCNF is not required for repression of pluripotency genes in mouse fetal ovarian germ cells. PLoS One (2013) 0.78
Disruption of CHTF18 causes defective meiotic recombination in male mice. PLoS Genet (2012) 0.77
NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism. Cell Metab (2015) 0.77
Making gametes from pluripotent stem cells: embryonic stem cells or very small embryonic-like stem cells? Stem Cell Investig (2016) 0.75
Generation of In-vitro Spermatogonial Stem Cells following Genetic Manipulation of Primordial Germ-like Cells. Avicenna J Med Biotechnol (2012) 0.75
Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin. Sci Rep (2017) 0.75
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature (2008) 10.11
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42
Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell (2011) 6.22
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58
Blimp1 is a critical determinant of the germ cell lineage in mice. Nature (2005) 5.49
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell (2006) 4.61
Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet (2010) 4.27
An improved single-cell cDNA amplification method for efficient high-density oligonucleotide microarray analysis. Nucleic Acids Res (2006) 4.26
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol Cell Biol (2005) 3.97
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell (2006) 3.79
CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol (2005) 3.54
Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nat Genet (2008) 3.52
Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. Hum Mol Genet (2007) 3.27
Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice. Development (2007) 3.06
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol (2005) 3.05
Offspring from oocytes derived from in vitro primordial germ cell-like cells in mice. Science (2012) 3.03
Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev (2008) 2.99
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96
Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice. Dev Biol (2005) 2.94
Global single-cell cDNA amplification to provide a template for representative high-density oligonucleotide microarray analysis. Nat Protoc (2007) 2.89
A signaling principle for the specification of the germ cell lineage in mice. Cell (2009) 2.81
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62
Efficient establishment of human embryonic stem cell lines and long-term maintenance with stable karyotype by enzymatic bulk passage. Biochem Biophys Res Commun (2006) 2.52
Stella is a maternal effect gene required for normal early development in mice. Curr Biol (2003) 2.38
Elucidation of phenotypic adaptations: Molecular analyses of dim-light vision proteins in vertebrates. Proc Natl Acad Sci U S A (2008) 2.34
Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc Natl Acad Sci U S A (2002) 2.34
Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes. Development (2011) 2.28
Efficient multicistronic expression of a transgene in human embryonic stem cells. Stem Cells (2007) 2.27
Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. J Clin Invest (2005) 2.25
Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice. Genes Dev (2008) 2.20
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors. Proc Natl Acad Sci U S A (2008) 2.17
Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol Cell Biol (2007) 2.15
Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling. Development (2008) 2.14
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion. Mol Cell (2013) 2.10
Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice. Proc Natl Acad Sci U S A (2006) 2.09
Pluripotential competence of cells associated with Nanog activity. Mech Dev (2005) 2.01
Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses. J Biol Chem (2002) 2.01
Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin. Cell Stem Cell (2008) 1.98
Tsix silences Xist through modification of chromatin structure. Dev Cell (2005) 1.97
PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells. Cell Stem Cell (2013) 1.96
Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem (2001) 1.96
External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. J Exp Med (2009) 1.95
Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression. PLoS One (2011) 1.95
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Development (2008) 1.94
Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells. Development (2012) 1.94
Establishment and characterization of cultured epithelial cells lacking expression of ZO-1. J Biol Chem (2004) 1.94
Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells. Proc Natl Acad Sci U S A (2003) 1.93
Nanog expression in mouse germ cell development. Gene Expr Patterns (2005) 1.86
MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev (2010) 1.84
A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Res (2010) 1.83
Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet (2007) 1.79
Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients. Hum Mol Genet (2007) 1.79
Gene expression dynamics during germline specification in mice identified by quantitative single-cell gene expression profiling. Biol Reprod (2006) 1.78
Generation of stella-GFP transgenic mice: a novel tool to study germ cell development. Genesis (2006) 1.72
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. In Vitro Cell Dev Biol Anim (2010) 1.70
Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells. Nat Commun (2012) 1.70
Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice. EMBO J (2012) 1.70
Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice. J Cell Biol (2005) 1.69
Histone code modifications on pluripotential nuclei of reprogrammed somatic cells. Mol Cell Biol (2004) 1.67
Pathway for differentiation of human embryonic stem cells to vascular cell components and their potential for vascular regeneration. Arterioscler Thromb Vasc Biol (2007) 1.63
Induction of mouse germ-cell fate by transcription factors in vitro. Nature (2013) 1.62
HLA-haplotype banking and iPS cells. Nat Biotechnol (2008) 1.61
A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Rep (2012) 1.60
Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice. Dev Biol (2006) 1.59
The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis. J Exp Med (2010) 1.59
Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs. Stem Cell Res (2010) 1.58
RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis. Development (2005) 1.58
Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases. PLoS Genet (2013) 1.57
Recombinant human laminin isoforms can support the undifferentiated growth of human embryonic stem cells. Biochem Biophys Res Commun (2008) 1.55
Mouse Tudor Repeat-1 (MTR-1) is a novel component of chromatoid bodies/nuages in male germ cells and forms a complex with snRNPs. Mech Dev (2003) 1.54
In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells. Invest Ophthalmol Vis Sci (2004) 1.52
Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol Biol Cell (2010) 1.51