Published in Hum Mol Genet on July 06, 2007
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Small RNAs as guardians of the genome. Cell (2009) 8.88
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A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell (2008) 6.35
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58
Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet (2010) 4.27
Rethinking how DNA methylation patterns are maintained. Nat Rev Genet (2009) 4.03
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet (2008) 3.89
Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev (2008) 2.99
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Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat Genet (2012) 2.35
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Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes. Development (2011) 2.28
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
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Zili is required for germ cell differentiation and meiosis in zebrafish. EMBO J (2008) 1.87
The take and give between retrotransposable elements and their hosts. Annu Rev Genet (2008) 1.86
A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Res (2010) 1.83
High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice. Genome Res (2013) 1.75
Coordinated chromatin control: structural and functional linkage of DNA and histone methylation. Biochemistry (2010) 1.74
Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers. Philos Trans R Soc Lond B Biol Sci (2013) 1.70
Small RNA guides for de novo DNA methylation in mammalian germ cells. Genes Dev (2008) 1.68
Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma. Epigenetics (2011) 1.55
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. Genes Dev (2014) 1.55
New insights into establishment and maintenance of DNA methylation imprints in mammals. Philos Trans R Soc Lond B Biol Sci (2013) 1.49
Cigarette smoking and DNA methylation. Front Genet (2013) 1.48
Molecular coupling of DNA methylation and histone methylation. Epigenomics (2010) 1.43
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity (2008) 1.43
DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo. PLoS Genet (2010) 1.41
Methylation analysis of 79 patients with growth restriction reveals novel patterns of methylation change at imprinted loci. Eur J Hum Genet (2010) 1.37
Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming. Cell Res (2011) 1.33
De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes Dev (2011) 1.32
Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming. Genome Biol (2015) 1.30
Genomic imprinting: recognition and marking of imprinted loci. Curr Opin Genet Dev (2011) 1.21
TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol (2011) 1.20
Retrotransposon-induced heterochromatin spreading in the mouse revealed by insertional polymorphisms. PLoS Genet (2011) 1.18
DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta. J Biol Chem (2010) 1.15
The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications. Cell Cycle (2012) 1.14
The evolution of epigenetic regulators CTCF and BORIS/CTCFL in amniotes. PLoS Genet (2008) 1.14
microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming. Cell Res (2012) 1.12
Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells. Genes Dev (2014) 1.11
CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19-Igf2 imprinting control region in prospermatogonia. PLoS Genet (2010) 1.07
Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos. RNA (2009) 1.07
Transcription and histone methylation changes correlate with imprint acquisition in male germ cells. EMBO J (2011) 1.06
Accumulation and loss of asymmetric non-CpG methylation during male germ-cell development. Nucleic Acids Res (2012) 1.05
DNA methylation pattern as important epigenetic criterion in cancer. Genet Res Int (2013) 1.00
Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci. J Biol Chem (2010) 1.00
More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domain. Front Genet (2012) 1.00
Two waves of de novo methylation during mouse germ cell development. Genes Dev (2014) 1.00
Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells. PLoS One (2012) 0.98
Structural and functional coordination of DNA and histone methylation. Cold Spring Harb Perspect Biol (2014) 0.98
Untangling the web: the diverse functions of the PIWI/piRNA pathway. Mol Reprod Dev (2013) 0.98
A repetitive elements perspective in Polycomb epigenetics. Front Genet (2012) 0.97
Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline. Cell Mol Life Sci (2013) 0.97
L1 retrotransposons, cancer stem cells and oncogenesis. FEBS J (2013) 0.97
The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals. Genes Dev (2014) 0.96
Dynamic nuclear organization of constitutive heterochromatin during fetal male germ cell development in mice. Biol Reprod (2009) 0.95
Sensitive quantitative analysis of murine LINE1 DNA methylation using high resolution melt analysis. Epigenetics (2012) 0.95
De novo DNA methylation in the male germ line occurs by default but is excluded at sites of H3K4 methylation. Cell Rep (2013) 0.95
Retrotransposition and genomic imprinting. Brief Funct Genomics (2010) 0.95
The regulation of non-coding RNA expression in the liver of mice fed DDC. Exp Mol Pathol (2009) 0.94
The paternal epigenome and embryogenesis: poising mechanisms for development. Asian J Androl (2010) 0.94
Epigenetic memory in mammals. Front Genet (2011) 0.93
Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis. Br J Cancer (2013) 0.93
The specification of imprints in mammals. Heredity (Edinb) (2014) 0.93
CG dinucleotide periodicities recognized by the Dnmt3a-Dnmt3L complex are distinctive at retroelements and imprinted domains. Mamm Genome (2009) 0.93
Estrogenic exposure alters the spermatogonial stem cells in the developing testis, permanently reducing crossover levels in the adult. PLoS Genet (2015) 0.93
Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development. Genome Res (2011) 0.93
Safeguarding parental identity: Dnmt1 maintains imprints during epigenetic reprogramming in early embryogenesis. Genes Dev (2008) 0.92
The MOV10 helicase inhibits LINE-1 mobility. J Biol Chem (2013) 0.90
Male germline control of transposable elements. Biol Reprod (2012) 0.90
Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond. Front Genet (2013) 0.90
Repeat-induced gene silencing of L1 transgenes is correlated with differential promoter methylation. Gene (2010) 0.89
Differential methylation persists at the mouse Rasgrf1 DMR in tissues displaying monoallelic and biallelic expression. Epigenetics (2009) 0.89
Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes. Nucleic Acids Res (2011) 0.89
DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination. Genes Dev (2015) 0.89
DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis. BMC Genomics (2015) 0.88
L1 expression and regulation in humans and rodents. Front Biosci (Elite Ed) (2012) 0.88
Comparative proteomics of human embryonic stem cells and embryonal carcinoma cells. Proteomics (2010) 0.88
Dynamic alterations in the paternal epigenetic landscape following fertilization. Front Genet (2012) 0.88
Multigenerational and transgenerational inheritance of drug exposure: The effects of alcohol, opiates, cocaine, marijuana, and nicotine. Prog Biophys Mol Biol (2015) 0.87
Role of ART in imprinting disorders. Semin Reprod Med (2012) 0.87
DNA demethylation and USF regulate the meiosis-specific expression of the mouse Miwi. PLoS Genet (2012) 0.87
Chromatin regulators of genomic imprinting. Biochim Biophys Acta (2013) 0.87
Lsh regulates LTR retrotransposon repression independently of Dnmt3b function. Genome Biol (2013) 0.87
Small RNAs, big impact: small RNA pathways in transposon control and their effect on the host stress response. Chromosome Res (2013) 0.86
Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome. PLoS One (2011) 0.85
Epigenetics in radiation biology: a new research frontier. Front Genet (2013) 0.85
Epigenetic dynamics during preimplantation development. Reproduction (2015) 0.85
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation. PLoS Genet (2015) 0.85
Sex-specific dynamics of global chromatin changes in fetal mouse germ cells. PLoS One (2011) 0.85
Maternal obesity and diabetes may cause DNA methylation alteration in the spermatozoa of offspring in mice. Reprod Biol Endocrinol (2014) 0.84
Establishment of paternal allele-specific DNA methylation at the imprinted mouse Gtl2 locus. Epigenetics (2011) 0.84
Hydrogen Sulfide Maintains Mitochondrial DNA Replication via Demethylation of TFAM. Antioxid Redox Signal (2015) 0.82
Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes. Nucleic Acids Res (2013) 0.82
Epigenetic regulation of human embryonic stem cells. Front Genet (2012) 0.82
The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins. Science (2002) 11.11
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev (2002) 10.54
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature (2008) 10.11
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol (2003) 9.13
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature (2007) 8.17
The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants. Science (2007) 8.12
The amphioxus genome and the evolution of the chordate karyotype. Nature (2008) 8.03
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell (2006) 7.08
The medaka draft genome and insights into vertebrate genome evolution. Nature (2007) 5.77
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells (2006) 5.68
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol (2003) 5.27
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol (2006) 5.16
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci (2010) 5.12
Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D. Nature (2004) 5.08
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development (2002) 4.72
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell (2006) 4.61
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science (2010) 4.60
Ongoing collapse of coral-reef shark populations. Curr Biol (2006) 4.48
Inducible antibacterial defense system in C. elegans. Curr Biol (2002) 4.42
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet (2008) 4.40
DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol (2006) 4.38
Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet (2010) 4.27
Maternal microRNAs are essential for mouse zygotic development. Genes Dev (2007) 4.16
TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat Immunol (2004) 4.11
Dynamic CpG island methylation landscape in oocytes and preimplantation embryos. Nat Genet (2011) 3.99
QUMA: quantification tool for methylation analysis. Nucleic Acids Res (2008) 3.73
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nat Genet (2007) 3.63
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol (2002) 3.61
CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol (2005) 3.54
Regulation of muscle growth by multiple ligands signaling through activin type II receptors. Proc Natl Acad Sci U S A (2005) 3.52
A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation. J Biol Chem (2002) 3.50
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci U S A (2003) 3.46
The landscape of C. elegans 3'UTRs. Science (2010) 3.32
Reconstruction of the vertebrate ancestral genome reveals dynamic genome reorganization in early vertebrates. Genome Res (2007) 3.12
Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites. Science (2008) 3.10
Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa. Nat Struct Mol Biol (2010) 3.07
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol (2005) 3.05
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation. Proc Natl Acad Sci U S A (2012) 3.03
Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev (2008) 2.99
KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature (2009) 2.98
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96
Histone H3-K9 methyltransferase ESET is essential for early development. Mol Cell Biol (2004) 2.92
Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks. PLoS Genet (2012) 2.89
MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis. PLoS One (2008) 2.82
Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age. Proc Natl Acad Sci U S A (2003) 2.54
Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity. Development (2008) 2.53
De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J Exp Med (2007) 2.50
Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression. Mol Cell Biol (2006) 2.48
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol (2008) 2.43
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res (2005) 2.42
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet (2008) 2.35
Comparative genomics of Physcomitrella patens gametophytic transcriptome and Arabidopsis thaliana: implication for land plant evolution. Proc Natl Acad Sci U S A (2003) 2.33
The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Mol Cell Biol (2004) 2.30
Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes. Development (2011) 2.28
Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity. Proc Natl Acad Sci U S A (2004) 2.21
Sequence analysis of the genome of an oil-bearing tree, Jatropha curcas L. DNA Res (2010) 2.19
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol Cell Biol (2007) 2.15
Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation. J Biol Chem (2004) 2.15
Lack of collagen XVIII/endostatin results in eye abnormalities. EMBO J (2002) 2.13
Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J Biol Chem (2005) 2.10
DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages. Development (2006) 2.08
Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells. J Biol Chem (2005) 2.04
Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses. J Biol Chem (2002) 2.01
The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine. Dev Biol (2006) 2.00
Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo. Mol Cell (2008) 1.99
Tsix silences Xist through modification of chromatin structure. Dev Cell (2005) 1.97
Functional dynamics of H3K9 methylation during meiotic prophase progression. EMBO J (2007) 1.96
Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem (2001) 1.96
External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. J Exp Med (2009) 1.95
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
Establishment and characterization of cultured epithelial cells lacking expression of ZO-1. J Biol Chem (2004) 1.94
Structure and function of eukaryotic DNA methyltransferases. Curr Top Dev Biol (2004) 1.91
MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev (2010) 1.84
Neurobehavioral and electroencephalographic abnormalities in Ube3a maternal-deficient mice. Neurobiol Dis (2002) 1.84
A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Res (2010) 1.83
De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation. Gene (2002) 1.80
Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet (2007) 1.79