Published in J Neurosci on November 11, 2009
Acid-sensing ion channels in pain and disease. Nat Rev Neurosci (2013) 1.93
Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death. J Neurosci (2011) 1.69
Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a. Int J Physiol Pathophysiol Pharmacol (2010) 1.42
Prodynorphin mutations cause the neurodegenerative disorder spinocerebellar ataxia type 23. Am J Hum Genet (2010) 1.27
Structure and activity of the acid-sensing ion channels. Am J Physiol Cell Physiol (2012) 1.25
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci (2011) 1.12
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ENaCs and ASICs as therapeutic targets. Am J Physiol Cell Physiol (2012) 0.91
PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner. Mol Brain (2010) 0.90
Developmental change in the electrophysiological and pharmacological properties of acid-sensing ion channels in CNS neurons. J Physiol (2010) 0.89
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Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant. J Biol Chem (2010) 0.88
Acid-sensing ion channels in pathological conditions. Adv Exp Med Biol (2013) 0.87
Translational strategies for neuroprotection in ischemic stroke--focusing on acid-sensing ion channel 1a. Transl Stroke Res (2014) 0.86
Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation. PLoS One (2013) 0.86
ASIC1a activation enhances inhibition in the basolateral amygdala and reduces anxiety. J Neurosci (2014) 0.85
The interaction between the first transmembrane domain and the thumb of ASIC1a is critical for its N-glycosylation and trafficking. PLoS One (2011) 0.85
Cysteine 149 in the extracellular finger domain of acid-sensing ion channel 1b subunit is critical for zinc-mediated inhibition. Neuroscience (2011) 0.85
Retracted Identification of SPLUNC1's ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways. FASEB J (2012) 0.85
The role of ASICS in cerebral ischemia. Wiley Interdiscip Rev Membr Transp Signal (2012) 0.84
Acid-sensing ion channels in mouse olfactory bulb M/T neurons. J Gen Physiol (2014) 0.83
Neuroprotective potential of biphalin, multireceptor opioid peptide, against excitotoxic injury in hippocampal organotypic culture. Neurochem Res (2011) 0.83
Two aspects of ASIC function: Synaptic plasticity and neuronal injury. Neuropharmacology (2015) 0.81
Calcium-permeable ion channels involved in glutamate receptor-independent ischemic brain injury. Acta Pharmacol Sin (2011) 0.80
Three distinct motifs within the C-terminus of acid-sensing ion channel 1a regulate its surface trafficking. Neuroscience (2013) 0.80
Structural mechanisms underlying the function of epithelial sodium channel/acid-sensing ion channel. Curr Opin Nephrol Hypertens (2011) 0.78
ASICs and neuropeptides. Neuropharmacology (2015) 0.78
Region specific contribution of ASIC2 to acidosis-and ischemia-induced neuronal injury. J Cereb Blood Flow Metab (2016) 0.78
Bile acids potentiate proton-activated currents in Xenopus laevis oocytes expressing human acid-sensing ion channel (ASIC1a). Physiol Rep (2017) 0.75
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Endogenous Isoquinoline Alkaloids Agonists of Acid-Sensing Ion Channel Type 3. Front Mol Neurosci (2017) 0.75
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Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. J Neurosci (2003) 3.05
Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels. J Biol Chem (2000) 2.85
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Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. Nat Med (2007) 2.28
Dynorphin A activates bradykinin receptors to maintain neuropathic pain. Nat Neurosci (2006) 2.23
Seizure termination by acidosis depends on ASIC1a. Nat Neurosci (2008) 2.18
Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons. J Biol Chem (2004) 2.15
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Restoring Acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses. J Neurosci (2008) 1.90
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Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels. Neuron (2000) 1.81
The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinity. J Gen Physiol (2005) 1.57
Interaction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependent. J Gen Physiol (2006) 1.51
30 years of dynorphins--new insights on their functions in neuropsychiatric diseases. Pharmacol Ther (2009) 1.50
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Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability. Neuropharmacology (2003) 0.99
Strong modulation by RFamide neuropeptides of the ASIC1b/3 heteromer in competition with extracellular calcium. Neuropharmacology (2006) 0.99
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Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia. Proc Natl Acad Sci U S A (2008) 3.21
Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. J Neurosci (2003) 3.05
Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors. Mol Biol Cell (2008) 2.73
Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. Proc Natl Acad Sci U S A (2004) 1.77
Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death. J Neurosci (2011) 1.69
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cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1. Proc Natl Acad Sci U S A (2003) 1.13
Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout mice. J Neurophysiol (2007) 1.09
ASIC3 and ASIC1 mediate FMRFamide-related peptide enhancement of H+-gated currents in cultured dorsal root ganglion neurons. J Neurophysiol (2003) 1.05
Endogenous arginine-phenylalanine-amide-related peptides alter steady-state desensitization of ASIC1a. J Biol Chem (2007) 1.03
Potentiation of acid-sensing ion channels by sulfhydryl compounds. Am J Physiol Cell Physiol (2007) 0.93
Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant. J Biol Chem (2010) 0.88
Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation. PLoS One (2013) 0.86
Ultrasound-mediated gene transfer into neuronal cells. J Biotechnol (2005) 0.81