Published in G3 (Bethesda) on March 01, 2013
Drosophila Chemoreceptors: A Molecular Interface Between the Chemical World and the Brain. Trends Genet (2015) 0.99
Candidate ionotropic taste receptors in the Drosophila larva. Proc Natl Acad Sci U S A (2015) 0.92
Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseases. Gene (2016) 0.89
Identification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila. Cell Rep (2014) 0.86
The neurotranscriptome of the Aedes aegypti mosquito. BMC Genomics (2016) 0.85
Balboa binds to pickpocket in vivo and is required for mechanical nociception in Drosophila larvae. Curr Biol (2014) 0.84
Cav3-type α1T calcium channels mediate transient calcium currents that regulate repetitive firing in Drosophila antennal lobe PNs. J Neurophysiol (2013) 0.82
Natural antisense transcripts regulate the neuronal stress response and excitability. Elife (2014) 0.81
Drosophila divalent metal ion transporter Malvolio is required in dopaminergic neurons for feeding decisions. Genes Brain Behav (2017) 0.76
The neural basis for insect pheromonal communication. Curr Opin Insect Sci (2015) 0.75
miR-263a Regulates ENaC to Maintain Osmotic and Intestinal Stem Cell Homeostasis in Drosophila. Dev Cell (2016) 0.75
The Drosophila Postsynaptic DEG/ENaC Channel ppk29 Contributes to Excitatory Neurotransmission. J Neurosci (2017) 0.75
Complex evolutionary dynamics of massively expanded chemosensory receptor families in an extreme generalist chelicerate herbivore. Genome Biol Evol (2016) 0.75
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol (2003) 102.57
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics (2006) 87.59
Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol (1993) 64.61
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (1993) 58.26
A rapid bootstrap algorithm for the RAxML Web servers. Syst Biol (2008) 38.22
The Pfam protein families database. Nucleic Acids Res (2011) 33.46
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Mol Syst Biol (2011) 28.61
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
ProtTest: selection of best-fit models of protein evolution. Bioinformatics (2005) 19.16
Evolution of genes and genomes on the Drosophila phylogeny. Nature (2007) 18.01
HMMER web server: interactive sequence similarity searching. Nucleic Acids Res (2011) 13.00
Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Nat Genet (2007) 12.62
The developmental transcriptome of Drosophila melanogaster. Nature (2010) 11.85
Unlocking the secrets of the genome. Nature (2009) 11.80
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature (1994) 9.76
ProtTest 3: fast selection of best-fit models of protein evolution. Bioinformatics (2011) 8.68
Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. Nature (2007) 8.04
A proton-gated cation channel involved in acid-sensing. Nature (1997) 6.98
The receptors and cells for mammalian taste. Nature (2006) 6.32
Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell (2004) 6.15
Epithelial sodium channels: function, structure, and regulation. Physiol Rev (1997) 5.90
Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol Rev (2002) 5.87
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals. Nat Neurosci (2004) 4.52
Nociceptive neurons protect Drosophila larvae from parasitoid wasps. Curr Biol (2007) 4.07
The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice. Neuron (2001) 3.56
PAL: an object-oriented programming library for molecular evolution and phylogenetics. Bioinformatics (2001) 3.34
Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons. Proc Natl Acad Sci U S A (2002) 3.05
The cells and peripheral representation of sodium taste in mice. Nature (2010) 2.80
Neurosensory mechanotransduction. Nat Rev Mol Cell Biol (2009) 2.73
The role of Drosophila Piezo in mechanical nociception. Nature (2012) 2.72
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel. Cell (1995) 2.47
Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel. Am J Physiol (1995) 2.38
Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel. Nature (1995) 2.32
Enhanced locomotion caused by loss of the Drosophila DEG/ENaC protein Pickpocket1. Curr Biol (2003) 2.25
Eukaryotic mechanosensitive channels. Annu Rev Biophys (2010) 2.23
Pickpocket is a DEG/ENaC protein required for mechanical nociception in Drosophila larvae. Curr Biol (2010) 2.20
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A (2006) 2.16
Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons. J Biol Chem (2004) 2.15
Chromosomal rearrangement inferred from comparisons of 12 Drosophila genomes. Genetics (2008) 2.09
The ion channel ASIC2 is required for baroreceptor and autonomic control of the circulation. Neuron (2009) 1.97
Contact chemoreceptors mediate male-male repulsion and male-female attraction during Drosophila courtship. Cell (2012) 1.96
DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptor. Neuron (2011) 1.90
Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits expressed in early development and in mechanosensory neurons. J Cell Biol (1998) 1.82
Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels. Neuron (2000) 1.81
Contribution of Drosophila DEG/ENaC genes to salt taste. Neuron (2003) 1.65
A nonproton ligand sensor in the acid-sensing ion channel. Neuron (2010) 1.52
Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits. J Biol Chem (1998) 1.49
MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain. Curr Biol (2004) 1.47
Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels. J Neurosci (2004) 1.40
Number of subunits comprising the epithelial sodium channel. J Biol Chem (1999) 1.38
Gating induces a conformational change in the outer vestibule of ENaC. J Gen Physiol (2000) 1.37
Protons at the gate: DEG/ENaC ion channels help us feel and remember. Neuron (2002) 1.35
Drosophila DEG/ENaC pickpocket genes are expressed in the tracheal system, where they may be involved in liquid clearance. Proc Natl Acad Sci U S A (2003) 1.33
ASIC2 subunits target acid-sensing ion channels to the synapse via an association with PSD-95. J Neurosci (2009) 1.33
The Drosophila female aphrodisiac pheromone activates ppk23(+) sensory neurons to elicit male courtship behavior. Cell Rep (2012) 1.30
Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits. Proc Natl Acad Sci U S A (2009) 1.29
ppk23-Dependent chemosensory functions contribute to courtship behavior in Drosophila melanogaster. PLoS Genet (2012) 1.27
Mechanosensation and the DEG/ENaC ion channels. Science (1996) 1.27
Amiloride-sensitive channels are a major contributor to mechanotransduction in mammalian muscle spindles. J Physiol (2009) 1.26
Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death. J Neurosci (2009) 1.22
Eukaryotic operon-like transcription of functionally related genes in Drosophila. Proc Natl Acad Sci U S A (2006) 1.20
A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Proc Natl Acad Sci U S A (2005) 1.16
Dendritic filopodia, Ripped Pocket, NOMPC, and NMDARs contribute to the sense of touch in Drosophila larvae. Curr Biol (2012) 1.12
Interactions between subunits of the human epithelial sodium channel. J Biol Chem (1997) 1.11
The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neurons. J Neurosci (2011) 1.10
A peptide-gated ion channel from the freshwater polyp Hydra. J Biol Chem (2007) 1.08
A Drosophila DEG/ENaC subunit functions specifically in gustatory neurons required for male courtship behavior. J Neurosci (2012) 1.05
Three homologous subunits form a high affinity peptide-gated ion channel in Hydra. J Biol Chem (2010) 1.05
ASIC3 and ASIC1 mediate FMRFamide-related peptide enhancement of H+-gated currents in cultured dorsal root ganglion neurons. J Neurophysiol (2003) 1.05
MEC-2 and MEC-6 in the Caenorhabditis elegans sensory mechanotransduction complex: auxiliary subunits that enable channel activity. J Gen Physiol (2008) 1.04
Endogenous arginine-phenylalanine-amide-related peptides alter steady-state desensitization of ASIC1a. J Biol Chem (2007) 1.03
An external site controls closing of the epithelial Na+ channel ENaC. J Physiol (2002) 1.03
Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability. Neuropharmacology (2003) 0.99
Potentiation of acid-sensing ion channels by sulfhydryl compounds. Am J Physiol Cell Physiol (2007) 0.93
dGNaC1, a gonad-specific amiloride-sensitive Na+ channel. J Biol Chem (1998) 0.92
The neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFamide) directly gates two ion channels in an identified Helix neurone. Pflugers Arch (1994) 0.92
Intersubunit interactions between mutant DEG/ENaCs induce synthetic neurotoxicity. Cell Death Differ (2008) 0.90
Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC). Adv Genet (2011) 0.88
Degenerins. At the core of the metazoan mechanotransducer? Ann N Y Acad Sci (2001) 0.87
Caenorhabditis elegans degenerins and vertebrate ENaC ion channels contain an extracellular domain related to venom neurotoxins. J Neurogenet (2000) 0.85
Mechanotransduction: touch and feel at the molecular level as modeled in Caenorhabditis elegans. Mol Neurobiol (2007) 0.85
The Drosophila gene CheB42a is a novel modifier of Deg/ENaC channel function. PLoS One (2010) 0.85
Evolution of the epithelial sodium channel and the sodium pump as limiting factors of aldosterone action on sodium transport. Physiol Genomics (2011) 0.82
Motile cilia of human airway epithelia are chemosensory. Science (2009) 4.40
Genomic dissection of behavioral maturation in the honey bee. Proc Natl Acad Sci U S A (2006) 2.16
Candidate genes for behavioural ecology. Trends Ecol Evol (2004) 1.90
TRPA channels distinguish gravity sensing from hearing in Johnston's organ. Proc Natl Acad Sci U S A (2009) 1.45
Natural variation in Drosophila melanogaster diapause due to the insulin-regulated PI3-kinase. Proc Natl Acad Sci U S A (2006) 1.36
ppk23-Dependent chemosensory functions contribute to courtship behavior in Drosophila melanogaster. PLoS Genet (2012) 1.27
amnesiac regulates sleep onset and maintenance in Drosophila melanogaster. Biochem Biophys Res Commun (2008) 1.12
Chemosensory functions for pulmonary neuroendocrine cells. Am J Respir Cell Mol Biol (2014) 1.06
The Drosophila gene CheB42a is a novel modifier of Deg/ENaC channel function. PLoS One (2010) 0.85
Natural antisense transcripts regulate the neuronal stress response and excitability. Elife (2014) 0.81
Feminization of pheromone-sensing neurons affects mating decisions in Drosophila males. Biol Open (2014) 0.77
Computational identification of operon-like transcriptional loci in eukaryotes. Comput Biol Med (2013) 0.76
Olfactory receptors in human airway epithelia. Methods Mol Biol (2013) 0.76