Published in Methods Mol Biol on January 01, 2010
3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells. Stem Cell Reports (2014) 2.42
FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling. Sci Transl Med (2014) 1.72
Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation, and epidermal organelles. J Invest Dermatol (2013) 1.68
The desmosomal protein desmoglein 1 aids recovery of epidermal differentiation after acute UV light exposure. J Invest Dermatol (2014) 1.43
Tenascin-C drives persistence of organ fibrosis. Nat Commun (2016) 1.41
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation. J Clin Invest (2013) 1.11
Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1. Mol Biol Cell (2010) 0.97
iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier function. Hum Mol Genet (2014) 0.95
Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering. Am J Pathol (2010) 0.95
Air-stimulated ATP release from keratinocytes occurs through connexin hemichannels. PLoS One (2013) 0.91
Alteration of the EphA2/Ephrin-A signaling axis in psoriatic epidermis. J Invest Dermatol (2012) 0.84
Eph/ephrin signaling in epidermal differentiation and disease. Semin Cell Dev Biol (2011) 0.82
Modeling AEC-New approaches to study rare genetic disorders. Am J Med Genet A (2014) 0.80
The retinoid-related orphan receptor RORα promotes keratinocyte differentiation via FOXN1. PLoS One (2013) 0.79
In Vitro Model of the Epidermis: Connecting Protein Function to 3D Structure. Methods Enzymol (2015) 0.79
Staphylococcus aureus Exploits Epidermal Barrier Defects in Atopic Dermatitis to Trigger Cytokine Expression. J Invest Dermatol (2016) 0.77
Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation. Mol Biol Cell (2014) 0.77
EphA2 proteomics in human keratinocytes reveals a novel association with afadin and epidermal tight junctions. J Cell Sci (2016) 0.75
Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission-fusion balance within mitochondrial networks. Nat Commun (2016) 0.75
The parathyroid hormone family member TIP39 interacts with sarco/endoplasmic reticulum Ca(2+) - ATPase activity by influencing calcium homeostasis. Exp Dermatol (2017) 0.75
Mechanism of filopodia initiation by reorganization of a dendritic network. J Cell Biol (2003) 5.47
Role of fascin in filopodial protrusion. J Cell Biol (2006) 3.52
Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end. Cell (2004) 3.48
The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription. Genes Dev (2008) 3.23
Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells. PLoS Biol (2007) 3.01
Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development. Sci Signal (2013) 2.78
MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia. Proc Natl Acad Sci U S A (2008) 2.25
p120 catenin associates with kinesin and facilitates the transport of cadherin-catenin complexes to intercellular junctions. J Cell Biol (2003) 2.02
Intercellular junction assembly, dynamics, and homeostasis. Cold Spring Harb Perspect Biol (2010) 1.96
Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis. J Cell Biol (2009) 1.73
FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling. Sci Transl Med (2014) 1.72
Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells. J Biol Chem (2004) 1.37
Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms. Proc Natl Acad Sci U S A (2005) 1.29
Cadherin switching in ovarian cancer progression. Int J Cancer (2003) 1.25
MicroRNA-205 promotes keratinocyte migration via the lipid phosphatase SHIP2. FASEB J (2010) 1.22
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes. J Biol Chem (2005) 1.17
Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor. J Biol Chem (2005) 1.15
Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus. Biol Reprod (2002) 1.14
microRNA-31/factor-inhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation. Proc Natl Acad Sci U S A (2012) 1.11
Keratinocyte expression of calcitonin gene-related peptide β: implications for neuropathic and inflammatory pain mechanisms. Pain (2011) 1.09
EGFR and ADAMs cooperate to regulate shedding and endocytic trafficking of the desmosomal cadherin desmoglein 2. Mol Biol Cell (2008) 1.07
The barrier function of skin: how to keep a tight lid on water loss. Trends Cell Biol (2002) 1.06
p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome. Hum Mol Genet (2012) 1.04
Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1. Mol Biol Cell (2010) 0.97
Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering. Am J Pathol (2010) 0.95
Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures. Cancer Res (2008) 0.94
Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer. J Clin Invest (2014) 0.92
Plakoglobin deficiency protects keratinocytes from apoptosis. J Invest Dermatol (2006) 0.89
Eph receptor and ephrin function in breast, gut, and skin epithelia. Cell Adh Migr (2014) 0.86
EphA2/Ephrin-A1 signaling complexes restrict corneal epithelial cell migration. Invest Ophthalmol Vis Sci (2012) 0.86
Alteration of the EphA2/Ephrin-A signaling axis in psoriatic epidermis. J Invest Dermatol (2012) 0.84
Desmosome regulation and signaling in disease. Cell Tissue Res (2015) 0.84
Eph/ephrin signaling in epidermal differentiation and disease. Semin Cell Dev Biol (2011) 0.82
microRNA-103/107 Family Regulates Multiple Epithelial Stem Cell Characteristics. Stem Cells (2015) 0.81
The retinoid-related orphan receptor RORα promotes keratinocyte differentiation via FOXN1. PLoS One (2013) 0.79
Insights from a desmoplakin mutation identified in lethal acantholytic epidermolysis bullosa. J Invest Dermatol (2010) 0.77