Published in J Cell Mol Med on November 13, 2009
Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties. Phys Biol (2011) 1.07
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials. Chem Rev (2015) 1.03
Synergistic effects of tethered growth factors and adhesion ligands on DNA synthesis and function of primary hepatocytes cultured on soft synthetic hydrogels. Biomaterials (2010) 0.90
Regulation of endothelial cell activation and angiogenesis by injectable peptide nanofibers. Acta Biomater (2011) 0.90
Development of a three-dimensional bone-like construct in a soft self-assembling peptide matrix. Tissue Eng Part A (2013) 0.81
Toward a 3D cellular model for studying in vitro the outcome of photodynamic treatments: accounting for the effects of tissue complexity. Tissue Eng Part A (2013) 0.78
Nanometric self-assembling peptide layers maintain adult hepatocyte phenotype in sandwich cultures. J Nanobiotechnology (2010) 0.78
Chondroitin Sulfate- and Decorin-Based Self-Assembling Scaffolds for Cartilage Tissue Engineering. PLoS One (2016) 0.78
Helix versus coil polypeptide macromers: gel networks with decoupled stiffness and permeability. Soft Matter (2012) 0.78
3D Cultivation Techniques for Primary Human Hepatocytes. Microarrays (Basel) (2015) 0.75
A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms. Stem Cell Rev (2017) 0.75
Effect of cell-cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells. FASEB J (1999) 4.22
Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane. Proc Natl Acad Sci U S A (1993) 4.05
Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. Am J Epidemiol (2002) 3.48
Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol Prog (1991) 3.21
Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB J (1989) 2.89
Osteogenic differentiation of mouse embryonic stem cells and mouse embryonic fibroblasts in a three-dimensional self-assembling peptide scaffold. Tissue Eng (2006) 2.35
Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc Natl Acad Sci U S A (1988) 2.30
Plasma fibronectin is synthesized and secreted by hepatocytes. J Biol Chem (1983) 2.25
Concern Crystal structure of human apolipoprotein A-I: insights into its protective effect against cardiovascular diseases. Proc Natl Acad Sci U S A (2006) 1.92
Effect of extracellular matrix topology on cell structure, function, and physiological responsiveness: hepatocytes cultured in a sandwich configuration. FASEB J (1996) 1.90
Structure, function and regulation of pyruvate carboxylase. Biochem J (1999) 1.76
Functional differentiation of hepatocyte-like spheroid structures from putative liver progenitor cells in three-dimensional peptide scaffolds. Differentiation (2003) 1.70
A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction. Curr Drug Metab (2005) 1.61
Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration. Am J Physiol (1994) 1.46
The effect of functionalized self-assembling peptide scaffolds on human aortic endothelial cell function. Biomaterials (2005) 1.45
Apolipoprotein A-I: structure-function relationships. J Lipid Res (2000) 1.31
Entrapment of migrating hippocampal neural cells in three-dimensional peptide nanofiber scaffold. Tissue Eng (2004) 1.30
Biological surface engineering: a simple system for cell pattern formation. Biomaterials (1999) 1.29
Molecular aspects of hepatobiliary transport. Am J Physiol (1997) 1.23
Functional behavior of primary rat liver cells in a three-dimensional perfused microarray bioreactor. Tissue Eng (2002) 1.16
The molecular basis of human 3-methylcrotonyl-CoA carboxylase deficiency. J Clin Invest (2001) 1.16
P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide. Pharm Res (2004) 1.15
Sequence and acute phase regulation of rat alpha 1-inhibitor III messenger RNA. J Biol Chem (1988) 1.06
Identification and characterization of glycosylation sites in human serum clusterin. Protein Sci (1997) 1.01
The rationale for using apoA-I as a clinical marker of cardiovascular risk. J Intern Med (2006) 0.99
Transport characterization of hydrogel matrices for cell encapsulation. Biotechnol Bioeng (1996) 0.98
Retinol-binding protein messenger RNA levels in the liver and in extrahepatic tissues of the rat. J Lipid Res (1986) 0.98
De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane. Mol Cell Biochem (2006) 0.97
Functional and structural properties of lipid-associated apolipoprotein J (clusterin). Biochem J (1999) 0.95
Characterization of four variant forms of human propionyl-CoA carboxylase expressed in Escherichia coli. J Biol Chem (2005) 0.94
Development and characterization of a small-scale bioreactor based on a bioartificial hepatic culture model for predictive pharmacological in vitro screenings. Biotechnol Bioeng (2006) 0.93
Transcellular transport of fluorescein in hepatocyte monolayers: evidence for functional polarity of cells in culture. Proc Natl Acad Sci U S A (1982) 0.93
Primary hepatocyte culture in collagen gel mixture and collagen sandwich. World J Gastroenterol (2004) 0.90
Reconstruction of 3D stacked-up structures by rat small hepatocytes on microporous membranes. FASEB J (2005) 0.89
HAPTOGLOBIN SYNTHESIS. I. IN VIVO STUDIES OF THE PRODUCTION OF HAPTOGLOBIN, FIBRINOGEN, AND GAMMA-GLOBULIN BY THE CANINE LIVER. J Clin Invest (1965) 0.88
Regulation of cultured rat hepatocyte proliferation by stellate cells. J Hepatol (2002) 0.88
Hepatic transcription of the acute-phase alpha 1-inhibitor III gene is controlled by a novel combination of cis-acting regulatory elements. Mol Cell Biol (1990) 0.87
Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes. Drug Metab Dispos (2004) 0.87
Isolation of rat serum alpha 1-microglobulin. Identification of a complex with alpha 1-inhibitor-3, a rat alpha 2-macroglobulin homologue. J Biol Chem (1990) 0.86
Transient expression of clusterin (sulfated glycoprotein-2) during development of rat pancreas. J Endocrinol (1998) 0.85
Long-term maintenance of human hepatocytes in oxygen-permeable membrane bioreactor. Biomaterials (2006) 0.85
Refinement of an in vitro cell model for cytochrome P450 induction. Drug Metab Dispos (1998) 0.84
Characterization of the secreted proteome of rat hepatocytes cultured in collagen sandwiches. Chem Res Toxicol (2005) 0.82
Perfusion of medium with supplemented growth factors changes metabolic activities and cell morphology of hepatocyte-nonparenchymal cell coculture. Tissue Eng (2004) 0.82
Tissue distribution of the lipocalin alpha-1 microglobulin in the developing human fetus. J Histochem Cytochem (2000) 0.82
Binding of acellular, native and cross-linked human hemoglobins to haptoglobin: enhanced distribution and clearance in the rat. Am J Physiol Gastrointest Liver Physiol (2005) 0.80
Dexamethasone effects on rat hepatocyte spheroid formation and function. Tissue Eng (2005) 0.79
Preservation of the synthetic and metabolic capacity of isolated human hepatocytes by coculture with human biliary epithelial cells. Liver Transpl (2005) 0.79
An array of binding sites for hepatocyte nuclear factor 4 of high and low affinities modulates the liver-specific enhancer for the human alpha1-microglobulin/bikunin precursor. Biochem J (1998) 0.78
New modified polyetheretherketone membrane for liver cell culture in biohybrid systems: adhesion and specific functions of isolated hepatocytes. Biomaterials (2004) 0.77
Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study. Lancet (2012) 4.54
Engineering principles of clinical cell-based tissue engineering. J Bone Joint Surg Am (2004) 2.79
Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus. J Cell Sci (2002) 2.42
Osteogenic differentiation of mouse embryonic stem cells and mouse embryonic fibroblasts in a three-dimensional self-assembling peptide scaffold. Tissue Eng (2006) 2.35
Tethered epidermal growth factor provides a survival advantage to mesenchymal stem cells. Stem Cells (2007) 2.03
Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties. Drug Metab Dispos (2003) 2.01
Microfluidic shear devices for quantitative analysis of cell adhesion. Anal Chem (2004) 1.95
Perfused multiwell plate for 3D liver tissue engineering. Lab Chip (2009) 1.88
A microfabricated array bioreactor for perfused 3D liver culture. Biotechnol Bioeng (2002) 1.87
Repair of chronic osteochondral defects using predifferentiated mesenchymal stem cells in an ovine model. Am J Sports Med (2010) 1.81
Epidermal growth factor as a candidate for ex vivo expansion of bone marrow-derived mesenchymal stem cells. Stem Cells (2005) 1.66
Transport-mediated angiogenesis in 3D epithelial coculture. FASEB J (2009) 1.58
Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity. Toxicol Appl Pharmacol (2009) 1.49
Tissue engineering for articular cartilage repair--the state of the art. Eur Cell Mater (2013) 1.48
Inhibition of neo-intimal hyperplasia in porcine coronary arteries utilizing a novel paclitaxel-coated scoring balloon catheter. Catheter Cardiovasc Interv (2013) 1.46
A three-dimensional osteochondral composite scaffold for articular cartilage repair. Biomaterials (2002) 1.46
The effect of functionalized self-assembling peptide scaffolds on human aortic endothelial cell function. Biomaterials (2005) 1.45
Multilineage differentiation potential of human dermal skin-derived fibroblasts. Exp Dermatol (2008) 1.44
Quantum dots for human mesenchymal stem cells labeling. A size-dependent autophagy activation. Nano Lett (2006) 1.43
Design peptide scaffolds for regenerative medicine. Adv Exp Med Biol (2003) 1.40
Growth factor regulation of proliferation and survival of multipotential stromal cells. Stem Cell Res Ther (2010) 1.39
Rat liver sinusoidal endothelial cells survive without exogenous VEGF in 3D perfused co-cultures with hepatocytes. FASEB J (2007) 1.35
Alpha4beta1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development. J Cell Biol (2007) 1.35
An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha. Hepatology (2008) 1.30
Cartilage tissue engineering and bioreactor systems for the cultivation and stimulation of chondrocytes. Eur Biophys J (2007) 1.25
Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities. Integr Biol (Camb) (2010) 1.20
Morphogenetic and regulatory mechanisms during developmental chondrogenesis: new paradigms for cartilage tissue engineering. Tissue Eng Part B Rev (2009) 1.17
Liver tissue engineering in the evaluation of drug safety. Expert Opin Drug Metab Toxicol (2009) 1.17
Functional behavior of primary rat liver cells in a three-dimensional perfused microarray bioreactor. Tissue Eng (2002) 1.16
Simulations of cell-surface integrin binding to nanoscale-clustered adhesion ligands. Biophys J (2002) 1.15
Interstitial fluid flow intensity modulates endothelial sprouting in restricted Src-activated cell clusters during capillary morphogenesis. Tissue Eng Part A (2009) 1.14
In vitro models for liver toxicity testing. Toxicol Res (Camb) (2012) 1.13
Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: tissue-specific stem cells. Stem Cells (2009) 1.11
Intraoperative detection and removal of microscopic residual sarcoma using wide-field imaging. Cancer (2012) 1.11
Gene delivery properties of end-modified poly(beta-amino ester)s. Bioconjug Chem (2007) 1.11
Both epithelial cells and mesenchymal stem cell-derived chondrocytes contribute to the survival of tissue-engineered airway transplants in pigs. J Thorac Cardiovasc Surg (2009) 1.06
An engineered bivalent neuregulin protects against doxorubicin-induced cardiotoxicity with reduced proneoplastic potential. Circulation (2013) 1.06
Simple generation of human induced pluripotent stem cells using poly-beta-amino esters as the non-viral gene delivery system. J Biol Chem (2011) 1.06
Marrow-derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness. Biotechnol Bioeng (2011) 1.05
Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation. Mol Biosyst (2010) 1.04
Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis. J Cell Sci (2006) 1.04
New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metab Rev (2003) 1.04
Mass transfer and metabolic reactions in hepatocyte spheroids cultured in rotating wall gas-permeable membrane system. Biomaterials (2007) 1.03
ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling. Proc Natl Acad Sci U S A (2013) 1.02
Sustained epidermal growth factor receptor levels and activation by tethered ligand binding enhances osteogenic differentiation of multi-potent marrow stromal cells. J Cell Physiol (2009) 1.02
Clonal expansion of adult rat hepatic stem cell lines by suppression of asymmetric cell kinetics (SACK). Biotechnol Bioeng (2003) 1.01
Interplay between PEO tether length and ligand spacing governs cell spreading on RGD-modified PMMA-g-PEO comb copolymers. Biomacromolecules (2007) 1.00
Quantitative real-time polymerase chain reaction: methodical analysis and mathematical model. J Biomol Tech (2004) 0.99
Matrix-associated implantation of predifferentiated mesenchymal stem cells versus articular chondrocytes: in vivo results of cartilage repair after 1 year. Am J Sports Med (2011) 0.99
Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays. Tissue Eng Part A (2011) 0.99
Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation. Sci Transl Med (2014) 0.99
Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells. Stem Cell Rev (2015) 0.98
Hydrogel doped with nanoparticles for local sustained release of siRNA in breast cancer. Adv Healthc Mater (2014) 0.97
Chain Conformations at the Surface of a Polydisperse Amphiphilic Comb Copolymer Film. Macromolecules (2006) 0.96
Biomechanical modulation of collagen fragment-induced anabolic and catabolic activities in chondrocyte/agarose constructs. Arthritis Res Ther (2010) 0.96
Interrogating signaling nodes involved in cellular transformations using kinase activity probes. Chem Biol (2012) 0.95
Development and characterization of a small-scale bioreactor based on a bioartificial hepatic culture model for predictive pharmacological in vitro screenings. Biotechnol Bioeng (2006) 0.93
Connected culture of murine hepatocytes and HUVEC in a multicompartmental bioreactor. Tissue Eng Part A (2009) 0.92
Influence of culture time on the expression of drug-metabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2. J Biochem Mol Toxicol (2003) 0.92
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis. J Am Chem Soc (2012) 0.92
ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein. J Biol Chem (2011) 0.92
Analysis of stem cell lipids by offline HPTLC-MALDI-TOF MS. Anal Bioanal Chem (2008) 0.92
Porcine endogenous retrovirus released by a bioartificial liver infects primary human cells. Liver Int (2009) 0.92
Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice. Cancer Res (2008) 0.91
Evaluation of cell behaviour related to physico-chemical properties of polymeric membranes to be used in bioartificial organs. Biomaterials (2002) 0.91
The influence of tethered epidermal growth factor on connective tissue progenitor colony formation. Biomaterials (2009) 0.90
Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs. Biotechnol Bioeng (2008) 0.90
Synergistic effects of tethered growth factors and adhesion ligands on DNA synthesis and function of primary hepatocytes cultured on soft synthetic hydrogels. Biomaterials (2010) 0.90
Cultivation of primary porcine hepatocytes in an OXY-HFB for use as a bioartificial liver device. Biotechnol Prog (2002) 0.89
Identification of human cells in brain xenografts and in neural co-cultures of rat by in situ hybridisation with Alu probe. J Neurosci Methods (2003) 0.89
Early tissue patterning recreated by mouse embryonic fibroblasts in a three-dimensional environment. Tissue Eng Part A (2009) 0.88
Impact of human autoantibodies on β1-adrenergic receptor conformation, activity, and internalization. Cardiovasc Res (2012) 0.88
Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator. J Am Chem Soc (2011) 0.88
Engineered bivalent ligands to bias ErbB receptor-mediated signaling and phenotypes. J Biol Chem (2011) 0.88
A bioartificial liver support system using primary hepatocytes: a preclinical study in a new porcine hepatectomy model. Surgery (2004) 0.87
Controlling multipotent stromal cell migration by integrating "course-graining" materials and "fine-tuning" small molecules via decision tree signal-response modeling. Biomaterials (2011) 0.87
RGD-dependent integrins are mechanotransducers in dynamically compressed tissue-engineered cartilage constructs. J Biomech (2009) 0.87
Transport and shear in a microfluidic membrane bilayer device for cell culture. Biomicrofluidics (2011) 0.87
Production of reactive oxygen species by multipotent stromal cells/mesenchymal stem cells upon exposure to fas ligand. Cell Transplant (2012) 0.87
The effect of self-assembling peptide nanofiber scaffolds on mouse embryonic fibroblast implantation and proliferation. Biomaterials (2008) 0.86
Formation of osteogenic colonies on well-defined adhesion peptides by freshly isolated human marrow cells. Biomaterials (2007) 0.86
The effect of sympathy on discriminatory attitudes toward persons living with HIV/AIDS in Puerto Rico: a hierarchical analysis of women living in public housing. AIDS Care (2009) 0.86
A versatile approach to engineering biomolecule-presenting cellular microenvironments. Adv Healthc Mater (2012) 0.86
A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytes. Conf Proc IEEE Eng Med Biol Soc (2009) 0.85
Long-term maintenance of human hepatocytes in oxygen-permeable membrane bioreactor. Biomaterials (2006) 0.85
Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death. Mol Cancer Ther (2009) 0.84
Thrombopoietin is a growth factor for rat hepatic progenitors. Eur J Gastroenterol Hepatol (2008) 0.84
The concept of in vivo airway tissue engineering. Biomaterials (2012) 0.84
Human hepatocyte functions in a crossed hollow fiber membrane bioreactor. Biomaterials (2009) 0.84
Determination of pore size distribution at the cell-hydrogel interface. J Nanobiotechnology (2011) 0.83
Photopatterning of hydrogel scaffolds coupled to filter materials using stereolithography for perfused 3D culture of hepatocytes. Biotechnol Bioeng (2015) 0.82
Determination of the decay rate constant for hepatocytes immobilized in alginate microcapsules. J Microencapsul (2010) 0.82
Improved preclinical safety assessment using micro-BAL devices: the potential impact on human discovery and drug attrition. Drug Discov Today (2011) 0.82
Gel entrapment culture of rat hepatocytes for investigation of tetracycline-induced toxicity. Toxicol Appl Pharmacol (2009) 0.82
A simple non-destructive method for the fixation and immunostaining of cultured cells encapsulated in alginate. Biotechnol Appl Biochem (2006) 0.82
Hepatotoxicity and hepatic metabolism of available drugs: current problems and possible solutions in preclinical stages. Expert Opin Drug Metab Toxicol (2010) 0.82
Tailoring chimeric ligands for studying and biasing ErbB receptor family interactions. Angew Chem Int Ed Engl (2014) 0.82