Published in Nucleic Acids Res on November 17, 2009
Revisiting the central dogma one molecule at a time. Cell (2011) 1.75
The architecture of Tetrahymena telomerase holoenzyme. Nature (2013) 1.32
Single-molecule approach to immunoprecipitated protein complexes: insights into miRNA uridylation. EMBO Rep (2011) 1.24
The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat Struct Mol Biol (2011) 1.14
Single-stranded DNA repeat synthesis by telomerase. Curr Opin Chem Biol (2011) 1.05
Single-molecule kinetics reveal cation-promoted DNA duplex formation through ordering of single-stranded helices. Biophys J (2013) 0.97
Functional importance of telomerase pseudoknot revealed by single-molecule analysis. Proc Natl Acad Sci U S A (2011) 0.95
Coordinated DNA dynamics during the human telomerase catalytic cycle. Nat Commun (2014) 0.95
Parallel multispot smFRET analysis using an 8-pixel SPAD array. Proc SPIE Int Soc Opt Eng (2012) 0.92
Roles of telomerase reverse transcriptase N-terminal domain in assembly and activity of Tetrahymena telomerase holoenzyme. J Biol Chem (2012) 0.90
A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition. J Biol Chem (2013) 0.85
Visualizing cellular machines with colocalization single molecule microscopy. Chem Soc Rev (2013) 0.84
Nanogel surface coatings for improved single-molecule imaging substrates. J R Soc Interface (2011) 0.84
The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids. Nucleic Acids Res (2015) 0.84
Single-molecule fluorescence resonance energy transfer studies of the human telomerase RNA pseudoknot: temperature-/urea-dependent folding kinetics and thermodynamics. J Phys Chem B (2014) 0.84
Single-molecule analysis of telomerase structure and function. Curr Opin Chem Biol (2011) 0.84
Progress in structural studies of telomerase. Curr Opin Struct Biol (2014) 0.79
Assays for detection of telomerase activity. Acta Naturae (2011) 0.77
Single-Molecule Studies of Telomeres and Telomerase. Annu Rev Biophys (2017) 0.75
Single-molecule FRET-Rosetta reveals RNA structural rearrangements during human telomerase catalysis. RNA (2016) 0.75
The lighthouse at the end of the chromosome. F1000Res (2015) 0.75
Specific association of human telomerase activity with immortal cells and cancer. Science (1994) 28.20
Energy transfer: a spectroscopic ruler. Proc Natl Acad Sci U S A (1967) 11.78
A practical guide to single-molecule FRET. Nat Methods (2008) 8.62
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature (2001) 7.95
Probing the interaction between two single molecules: fluorescence resonance energy transfer between a single donor and a single acceptor. Proc Natl Acad Sci U S A (1996) 7.65
A single-molecule study of RNA catalysis and folding. Science (2000) 7.06
Secondary structure of vertebrate telomerase RNA. Cell (2000) 6.37
Nonblinking and long-lasting single-molecule fluorescence imaging. Nat Methods (2006) 6.25
A conserved secondary structure for telomerase RNA. Cell (1991) 4.52
Fluorescence-aided molecule sorting: analysis of structure and interactions by alternating-laser excitation of single molecules. Proc Natl Acad Sci U S A (2004) 4.06
Telomerase modulates Wnt signalling by association with target gene chromatin. Nature (2009) 3.96
Beginning to understand the end of the chromosome. Cell (2004) 3.46
The biogenesis and regulation of telomerase holoenzymes. Nat Rev Mol Cell Biol (2006) 2.94
Telomerase is processive. Mol Cell Biol (1991) 2.79
Yeast telomerase RNA: a flexible scaffold for protein subunits. Proc Natl Acad Sci U S A (2004) 2.52
Structure of the Tribolium castaneum telomerase catalytic subunit TERT. Nature (2008) 2.17
Structure and function of telomerase RNA. Curr Opin Struct Biol (2006) 2.09
Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein. Nature (2007) 2.05
Template boundary definition in Tetrahymena telomerase. Genes Dev (2002) 1.96
The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers. Mol Cell Biol (1997) 1.94
A phylogenetically based secondary structure for the yeast telomerase RNA. Curr Biol (2004) 1.90
Roles for RNA in telomerase nucleotide and repeat addition processivity. Mol Cell (2003) 1.86
A molecular switch underlies a human telomerase disease. Proc Natl Acad Sci U S A (2002) 1.79
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein. Proc Natl Acad Sci U S A (1999) 1.74
Telomerase recognizes its template by using an adjacent RNA motif. Proc Natl Acad Sci U S A (2002) 1.61
A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity. Biochemistry (2001) 1.58
Ciliate telomerase biochemistry. Annu Rev Biochem (1999) 1.51
Stem-loop IV of tetrahymena telomerase RNA stimulates processivity in trans. Mol Cell Biol (2003) 1.49
Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. RNA (2006) 1.17
Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA. RNA (2007) 1.17
Single-molecule analysis of human telomerase monomer. Nat Chem Biol (2008) 1.16
Multiple DNA-binding sites in Tetrahymena telomerase. Nucleic Acids Res (2008) 1.12
Tracking telomerase. Cell (2004) 1.10
Tetrahymena telomerase is active as a monomer. Mol Biol Cell (2003) 1.10
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat Methods (2006) 30.70
Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy. Science (2008) 14.73
Multicolor super-resolution imaging with photo-switchable fluorescent probes. Science (2007) 9.00
Short-range spectroscopic ruler based on a single-molecule optical switch. Phys Rev Lett (2005) 6.08
Breaking the diffraction barrier: super-resolution imaging of cells. Cell (2010) 5.83
Super-resolution fluorescence microscopy. Annu Rev Biochem (2009) 5.47
Evaluation of fluorophores for optimal performance in localization-based super-resolution imaging. Nat Methods (2011) 5.25
Whole-cell 3D STORM reveals interactions between cellular structures with nanometer-scale resolution. Nat Methods (2008) 4.96
Fast, three-dimensional super-resolution imaging of live cells. Nat Methods (2011) 4.52
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis. Science (2011) 4.26
Visualizing infection of individual influenza viruses. Proc Natl Acad Sci U S A (2003) 4.10
Actin, spectrin, and associated proteins form a periodic cytoskeletal structure in axons. Science (2012) 4.07
Electrical detection of single viruses. Proc Natl Acad Sci U S A (2004) 3.83
Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes. Cell (2006) 3.83
Structural transitions and elasticity from torque measurements on DNA. Nature (2003) 3.71
Superresolution imaging of chemical synapses in the brain. Neuron (2010) 3.51
Imaging poliovirus entry in live cells. PLoS Biol (2007) 3.40
Dynamic binding orientations direct activity of HIV reverse transcriptase. Nature (2008) 2.94
Slide into action: dynamic shuttling of HIV reverse transcriptase on nucleic acid substrates. Science (2008) 2.78
Exploring the folding landscape of a structured RNA. Proc Natl Acad Sci U S A (2001) 2.78
Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells. PLoS Pathog (2008) 2.77
Assembly of endocytic machinery around individual influenza viruses during viral entry. Nat Struct Mol Biol (2004) 2.77
Nanotools for neuroscience and brain activity mapping. ACS Nano (2013) 2.74
Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton. Nat Methods (2012) 2.67
Virus trafficking - learning from single-virus tracking. Nat Rev Microbiol (2007) 2.59
Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc Natl Acad Sci U S A (2012) 2.46
Chromosome organization by a nucleoid-associated protein in live bacteria. Science (2011) 2.41
Endocytosis of influenza viruses. Microbes Infect (2004) 2.38
Molecular architecture and assembly principles of Vibrio cholerae biofilms. Science (2012) 2.36
Single-molecule transition-state analysis of RNA folding. Proc Natl Acad Sci U S A (2003) 2.31
Associated loss of fat-free mass and bone mineral density in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2004) 2.22
Single-molecule enzymology of RNA: essential functional groups impact catalysis from a distance. Proc Natl Acad Sci U S A (2004) 2.11
Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein. Nature (2007) 2.05
Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking. J Virol (2007) 2.03
Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque. Nat Struct Mol Biol (2007) 1.91
Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus. Proc Natl Acad Sci U S A (2008) 1.88
Photoswitching mechanism of cyanine dyes. J Am Chem Soc (2009) 1.86
Using single-particle tracking to study nuclear trafficking of viral genes. Biophys J (2004) 1.72
Dynamics of nucleosome remodelling by individual ACF complexes. Nature (2009) 1.68
Exploration of the transition state for tertiary structure formation between an RNA helix and a large structured RNA. J Mol Biol (2003) 1.67
Internalization and trafficking of cell surface proteoglycans and proteoglycan-binding ligands. Traffic (2007) 1.64
Statistical deconvolution for superresolution fluorescence microscopy. Biophys J (2012) 1.61
Ultrabright photoactivatable fluorophores created by reductive caging. Nat Methods (2012) 1.57
Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system. Nat Cell Biol (2010) 1.55
Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic "fingerprinting". Proc Natl Acad Sci U S A (2007) 1.48
Super-resolution microscopy by nanoscale localization of photo-switchable fluorescent probes. Curr Opin Chem Biol (2008) 1.46
Correlating pre-operative vitamin d status with post-thyroidectomy hypocalcemia. Endocr Pract (2014) 1.45
Single-molecule RNA folding. Acc Chem Res (2005) 1.43
Monocytes and γδ T cells control the acute-phase response to intravenous zoledronate: insights from a phase IV safety trial. J Bone Miner Res (2013) 1.36
Multicolor super-resolution fluorescence imaging via multi-parameter fluorophore detection. Chemphyschem (2011) 1.34
ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps. Cell (2013) 1.29
Two distinct binding modes of a protein cofactor with its target RNA. J Mol Biol (2006) 1.17
Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription. Nat Struct Mol Biol (2010) 1.15
The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat Struct Mol Biol (2011) 1.14
Influence of breast cancer margin assessment method on the rates of positive margins and residual carcinoma. Am J Surg (2006) 1.09
Early dysregulation of cell adhesion and extracellular matrix pathways in breast cancer progression. Am J Pathol (2009) 1.07
Fast compressed sensing analysis for super-resolution imaging using L1-homotopy. Opt Express (2013) 1.04
Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains. Nat Struct Mol Biol (2013) 1.03
Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. Antimicrob Agents Chemother (2010) 1.03
3D multicolor super-resolution imaging offers improved accuracy in neuron tracing. PLoS One (2012) 1.01
Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy. Nucleic Acids Res (2013) 1.01
Dissecting the role of COPI complexes in influenza virus infection. J Virol (2012) 0.99
Assembly of complex RNAs by splinted ligation. Methods Enzymol (2009) 0.96
Low bone mineral density in men with chronic obstructive pulmonary disease. Respir Res (2011) 0.96
Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain. Angew Chem Int Ed Engl (2012) 0.96
Functional importance of telomerase pseudoknot revealed by single-molecule analysis. Proc Natl Acad Sci U S A (2011) 0.95
Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells. J Exp Med (2014) 0.94
Phosphine quenching of cyanine dyes as a versatile tool for fluorescence microscopy. J Am Chem Soc (2013) 0.94
Luminescent and Raman active silver nanoparticles with polycrystalline structure. J Am Chem Soc (2008) 0.94
Robust reconstruction of the rate constant distribution using the phase function method. Biophys J (2006) 0.93
Rapid actin-dependent viral motility in live cells. Biophys J (2009) 0.92
Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes. J Cell Biol (2013) 0.92
Dual function of CD81 in influenza virus uncoating and budding. PLoS Pathog (2013) 0.92
Kinetic analysis of sequential multistep reactions. J Phys Chem B (2007) 0.91
The C-terminal domain of Tetrahymena thermophila telomerase holoenzyme protein p65 induces multiple structural changes in telomerase RNA. RNA (2012) 0.91
Pulmonary function, body composition, and protein catabolism in adults with cystic fibrosis. Am J Respir Crit Care Med (2002) 0.90
Live cell imaging of viral entry. Curr Opin Virol (2013) 0.90
Hidden depletion of fat-free mass and bone mineral density in adults with cystic fibrosis. Chest (2003) 0.90
Stochastic optical reconstruction microscopy (STORM): a method for superresolution fluorescence imaging. Cold Spring Harb Protoc (2013) 0.88
Contemporary diagnostic approach to the thyroid nodule. J Surg Oncol (2006) 0.88
Disentangling DNA during replication: a tale of two strands. Philos Trans R Soc Lond B Biol Sci (2004) 0.86
A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition. J Biol Chem (2013) 0.85
Single-molecule analysis of telomerase structure and function. Curr Opin Chem Biol (2011) 0.84
Susceptibility to Paget's disease of bone is influenced by a common polymorphic variant of osteoprotegerin. J Bone Miner Res (2004) 0.84
Molecular biology: Concealed enzyme coordination. Nature (2009) 0.78
New fluorescent probes for super-resolution imaging. Nat Biotechnol (2011) 0.77
Preparation of photoswitchable labeled antibodies for STORM imaging. Cold Spring Harb Protoc (2013) 0.77
Single-particle virus tracking. Cold Spring Harb Protoc (2011) 0.76
Monitoring conformational dynamics with single-molecule fluorescence energy transfer: applications in nucleosome remodeling. Methods Enzymol (2012) 0.76
Transfection of genetically encoded photoswitchable probes for STORM imaging. Cold Spring Harb Protoc (2013) 0.76
Single-virus tracking in live cells. Cold Spring Harb Protoc (2011) 0.76
Structural biology: a solution to the telomerase puzzle. Nature (2013) 0.75
Promoters and barriers to mammography screening in multiethnic inner city patients. Am J Surg (2009) 0.75
Tissue compression is not necessary for needle-localized lesion identification. Am J Surg (2005) 0.75
New technologies. Curr Opin Neurobiol (2010) 0.75