Published in Fertil Steril on November 25, 2009
Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations. PLoS One (2013) 1.88
Dioxin (TCDD) induces epigenetic transgenerational inheritance of adult onset disease and sperm epimutations. PLoS One (2012) 1.28
Hydrocarbons (jet fuel JP-8) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations. Reprod Toxicol (2013) 1.23
miRNA-93 inhibits GLUT4 and is overexpressed in adipose tissue of polycystic ovary syndrome patients and women with insulin resistance. Diabetes (2013) 1.17
Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations. Reprod Toxicol (2012) 1.12
Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome. Endocr Rev (2015) 1.06
Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline. PLoS One (2014) 1.05
Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys. PLoS One (2011) 1.00
MicroRNAs Related to Polycystic Ovary Syndrome (PCOS). Genes (Basel) (2014) 0.82
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Quantitative methylation level of the EPHX1 promoter in peripheral blood DNA is associated with polycystic ovary syndrome. PLoS One (2014) 0.79
The role of androgen receptor activity mediated by the CAG repeat polymorphism in the pathogenesis of PCOS. J Med Life (2013) 0.79
Effect of maternal PCOS and PCOS-like phenotype on the offspring's health. Mol Cell Endocrinol (2015) 0.78
Insulin resistance is not conserved in myotubes established from women with PCOS. PLoS One (2010) 0.77
A semi-quantitative assay of overall DNA methylation status using Methyl-CpG binding protein (MBD1). BMC Res Notes (2012) 0.77
Epigenetic modification of long interspersed elements-1 in cumulus cells of mature and immature oocytes from patients with polycystic ovary syndrome. Clin Exp Reprod Med (2016) 0.75
Integrated analyses for genetic markers of polycystic ovary syndrome with 9 case-control studies of gene expression profiles. Oncotarget (2016) 0.75
Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women. Oncotarget (2017) 0.75
Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell. Oncotarget (2016) 0.75
Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome. Sci Rep (2016) 0.75
Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A (2005) 15.46
The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab (2004) 7.96
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4. Cancer Res (2006) 5.92
Epigenetics at the epicenter of modern medicine. JAMA (2008) 2.42
Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome? Hum Reprod Update (2005) 2.07
Developmental estrogen exposures predispose to prostate carcinogenesis with aging. Reprod Toxicol (2006) 1.93
Polycystic ovary syndrome and its developmental origins. Rev Endocr Metab Disord (2007) 1.61
Individuality and epigenetics in obesity. Obes Rev (2009) 1.48
Polycystic ovary syndrome: a transgenerational evolutionary adaptation. BJOG (2008) 1.43
Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development. Genomics (2008) 1.42
Is epigenetics an important link between early life events and adult disease? Horm Res (2009) 1.29
Review: fetal programming of polycystic ovary syndrome by androgen excess: evidence from experimental, clinical, and genetic association studies. J Clin Endocrinol Metab (2006) 1.27
Hypermethylation of homeobox A10 by in utero diethylstilbestrol exposure: an epigenetic mechanism for altered developmental programming. Endocrinology (2009) 1.25
Global hypomethylation of peripheral leukocyte DNA in male patients with schizophrenia: a potential link between epigenetics and schizophrenia. J Psychiatr Res (2006) 1.18
The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome. J Clin Endocrinol Metab (2002) 1.15
Looking for polycystic ovary syndrome genes: rational and best strategy. Semin Reprod Med (2008) 1.09
Association of androgen receptor CAG repeat polymorphism and polycystic ovary syndrome. J Clin Endocrinol Metab (2008) 1.06
Programming of appetite and type 2 diabetes. Early Hum Dev (2005) 1.03
Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome. J Clin Endocrinol Metab (2006) 1.01
Androgen circle of polycystic ovary syndrome. Hum Reprod (2009) 1.01
Epigenetic abnormality: a possible mechanism underlying the fetal origin of polycystic ovary syndrome. Med Hypotheses (2007) 0.94
First evidence of genetic association between AKT2 and polycystic ovary syndrome. Diabetes Care (2008) 0.93
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab (2010) 3.80
Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. J Clin Endocrinol Metab (2006) 3.46
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol (2011) 3.02
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. Gastroenterology (2010) 2.45
Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab (2005) 2.28
Retracted Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health--National Heart, Lung, and Blood Institute sponsored Women's Ischemia Syndrome Evaluation. J Clin Endocrinol Metab (2008) 2.21
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes (2011) 2.09
Use of metformin in polycystic ovary syndrome. Am J Obstet Gynecol (2008) 1.92
Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment. Fertil Steril (2005) 1.82
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study. Diabetes (2008) 1.78
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome. Best Pract Res Clin Endocrinol Metab (2006) 1.56
CRTC3 links catecholamine signalling to energy balance. Nature (2010) 1.55
Insulin resistance, polycystic ovary syndrome, and type 2 diabetes mellitus. Fertil Steril (2002) 1.55
Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis. PLoS Genet (2012) 1.53
Laparoscopic evaluation following failure to achieve pregnancy after ovulation induction with clomiphene citrate. Fertil Steril (2003) 1.51
Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts. J Med Genet (2011) 1.51
The severity of menstrual dysfunction as a predictor of insulin resistance in PCOS. J Clin Endocrinol Metab (2013) 1.50
A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet (2013) 1.50
Dehydroepiandrosterone sulfate and insulin resistance in patients with polycystic ovary syndrome. Fertil Steril (2008) 1.49
Impact of obesity on the risk for polycystic ovary syndrome. J Clin Endocrinol Metab (2007) 1.44
Reproductive hormone exposure timing and ischemic heart disease: Complicated answers to a simple question. Maturitas (2010) 1.39
Fifteen-year trend in the use of male reproductive surgery: analysis of the healthcare cost and utilization project data. BJU Int (2011) 1.39
Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study. Hum Genet (2009) 1.36
Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups. Fertil Steril (2005) 1.34
Socioeconomic and racial predictors of undergoing laparoscopic hysterectomy for selected benign diseases: analysis of 341487 hysterectomies. J Minim Invasive Gynecol (2008) 1.33
Visually scoring hirsutism. Hum Reprod Update (2009) 1.21
Variants in the 5alpha-reductase type 1 and type 2 genes are associated with polycystic ovary syndrome and the severity of hirsutism in affected women. J Clin Endocrinol Metab (2006) 1.19
Health-related quality of life in women with polycystic ovary syndrome, a self-administered questionnaire, was validated. J Clin Epidemiol (2004) 1.18
Prevalence of adrenal androgen excess in patients with the polycystic ovary syndrome (PCOS). Clin Endocrinol (Oxf) (2005) 1.17
Nonclassic congenital adrenal hyperplasia. Int J Pediatr Endocrinol (2010) 1.17
miRNA-93 inhibits GLUT4 and is overexpressed in adipose tissue of polycystic ovary syndrome patients and women with insulin resistance. Diabetes (2013) 1.17
FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome. PLoS One (2011) 1.16
Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. Diabetes Care (2012) 1.15
Genome-wide association study in a Chinese population with diabetic retinopathy. Hum Mol Genet (2013) 1.13
Degree of facial and body terminal hair growth in unselected black and white women: toward a populational definition of hirsutism. J Clin Endocrinol Metab (2006) 1.13
Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans. J Clin Endocrinol Metab (2007) 1.12
Novel pathway of adipogenesis through cross-talk between adipose tissue macrophages, adipose stem cells and adipocytes: evidence of cell plasticity. PLoS One (2011) 1.12
A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. Hum Mol Genet (2011) 1.10
Prevalence of hyperandrogenemia in the polycystic ovary syndrome diagnosed by the National Institutes of Health 1990 criteria. Fertil Steril (2009) 1.10
The adrenal and polycystic ovary syndrome. Rev Endocr Metab Disord (2007) 1.09
Body adiposity index versus body mass index and other anthropometric traits as correlates of cardiometabolic risk factors. PLoS One (2013) 1.09
The predictive role of blood glucose for mortality in subjects with cardiovascular disease. Am J Epidemiol (2005) 1.09
Diagnosis of polycystic ovary syndrome. Clin Obstet Gynecol (2007) 1.08
Effects of race and family history of type 2 diabetes on metabolic status of women with polycystic ovary syndrome. J Clin Endocrinol Metab (2004) 1.06
Association of androgen receptor CAG repeat polymorphism and polycystic ovary syndrome. J Clin Endocrinol Metab (2008) 1.06
From the eye of the nurses: 360-degree evaluation of residents. J Contin Educ Health Prof (2009) 1.04
Congenital adrenal hyperplasia. J Pediatr Adolesc Gynecol (2011) 1.03
Diagnosis, phenotype, and prevalence of polycystic ovary syndrome. Fertil Steril (2006) 1.03
Defining hirsutism in Chinese women: a cross-sectional study. Fertil Steril (2011) 1.01
Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. Am J Hum Genet (2012) 1.01
Referral bias in defining the phenotype and prevalence of obesity in polycystic ovary syndrome. J Clin Endocrinol Metab (2013) 1.01
Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys. PLoS One (2011) 1.00
Difference in dietary intake between women with polycystic ovary syndrome and healthy controls. Fertil Steril (2006) 1.00
Total estrogen time and obstructive coronary disease in women: insights from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE). J Womens Health (Larchmt) (2009) 1.00
Polycystic ovary syndrome: an ancient disorder? Fertil Steril (2010) 0.99
Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA). Genet Epidemiol (2012) 0.99
Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension. J Clin Endocrinol Metab (2011) 0.98
Reanalyzing the modified Ferriman-Gallwey score: is there a simpler method for assessing the extent of hirsutism? Fertil Steril (2011) 0.97
Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing. Expert Rev Mol Diagn (2012) 0.97
Degree of hyperinsulinemia, independent of androgen levels, is an important determinant of the severity of hirsutism in PCOS. Fertil Steril (2008) 0.96
Genes for enzymes regulating dehydroepiandrosterone sulfonation are associated with levels of dehydroepiandrosterone sulfate in polycystic ovary syndrome. J Clin Endocrinol Metab (2007) 0.96
Role of diet in the treatment of polycystic ovary syndrome. Fertil Steril (2006) 0.95
The age-associated decline of androgens in reproductive age and menopausal Black and White women. J Clin Endocrinol Metab (2007) 0.95
Nonreplication of the type 5 17beta-hydroxysteroid dehydrogenase gene association with polycystic ovary syndrome. J Clin Endocrinol Metab (2007) 0.94
Replication of association of a novel insulin receptor gene polymorphism with polycystic ovary syndrome. Fertil Steril (2011) 0.94
A Summary of the Endocrine Society Clinical Practice Guidelines on Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency. Int J Pediatr Endocrinol (2010) 0.94
Improvement in endothelial structure and function after metformin treatment in young normal-weight women with polycystic ovary syndrome: results of a 6-month study. J Clin Endocrinol Metab (2005) 0.93
The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation. Atherosclerosis (2011) 0.93
The Associations Between Residents' Behavior and the Thomas-Kilmann Conflict MODE Instrument. J Grad Med Educ (2010) 0.93
Associations of SNPs in ADIPOQ and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis (MESA). Obesity (Silver Spring) (2010) 0.93
Relations between endogenous androgens and estrogens in postmenopausal women with suspected ischemic heart disease. J Clin Endocrinol Metab (2008) 0.93
Blood glucose: a strong risk factor for mortality in nondiabetic patients with cardiovascular disease. Am Heart J (2005) 0.93
First evidence of genetic association between AKT2 and polycystic ovary syndrome. Diabetes Care (2008) 0.93
Abnormal expression of genes involved in inflammation, lipid metabolism, and Wnt signaling in the adipose tissue of polycystic ovary syndrome. J Clin Endocrinol Metab (2012) 0.92
Relationship of insulin sensitivity, insulin secretion, and adiposity with insulin clearance in a multiethnic population: the insulin Resistance Atherosclerosis study. Diabetes Care (2012) 0.92
Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals. J Clin Endocrinol Metab (2015) 0.92
Laser hair reduction in the hirsute patient: a critical assessment. Hum Reprod Update (2002) 0.91
Adrenal function during childhood and puberty in daughters of women with polycystic ovary syndrome. J Clin Endocrinol Metab (2009) 0.91
Nonhuman primate models of polycystic ovary syndrome. Mol Cell Endocrinol (2013) 0.91
Genetic markers: progress and potential for cardiovascular disease. Circulation (2004) 0.91
A pilot randomized, single-blind, placebo-controlled trial of traditional acupuncture for vasomotor symptoms and mechanistic pathways of menopause. Menopause (2012) 0.90
Independent confirmation of association between metabolic phenotypes of polycystic ovary syndrome and variation in the type 6 17beta-hydroxysteroid dehydrogenase gene. J Clin Endocrinol Metab (2009) 0.90
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. J Clin Invest (2015) 0.90
DHEA-S levels and cardiovascular disease mortality in postmenopausal women: results from the National Institutes of Health--National Heart, Lung, and Blood Institute (NHLBI)-sponsored Women's Ischemia Syndrome Evaluation (WISE). J Clin Endocrinol Metab (2010) 0.89
Diagnosing the diagnosis: why we must standardize the defining features of polycystic ovary syndrome. Ann Clin Biochem (2008) 0.89
Genetic variants in peroxisome proliferator-activated receptor gamma influence insulin resistance and testosterone levels in normal women, but not those with polycystic ovary syndrome. Fertil Steril (2006) 0.89
Polycystic ovary syndrome in Mexican-Americans: prevalence and association with the severity of insulin resistance. Fertil Steril (2005) 0.89
Favourable metabolic effects of a eucaloric lower-carbohydrate diet in women with PCOS. Clin Endocrinol (Oxf) (2013) 0.89
Adipocytes from women with polycystic ovary syndrome demonstrate altered phosphorylation and activity of glycogen synthase kinase 3. Fertil Steril (2008) 0.89