Published in Cell Death Differ on December 04, 2009
Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology. Nat Rev Neurosci (2012) 1.69
Activation of apoptotic pathways in the absence of cell death in an inner-ear immortomouse cell line. Hear Res (2011) 1.51
Molecular mechanisms of neonatal brain injury. Neurol Res Int (2012) 1.07
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia. Cell Death Dis (2014) 0.97
Cell signaling underlying epileptic behavior. Front Behav Neurosci (2011) 0.96
The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival? Int J Mol Sci (2016) 0.94
CeeTox™ Analysis of CNB-001 a Novel Curcumin-Based Neurotrophic/Neuroprotective Lead Compound to Treat Stroke: Comparison with NXY-059 and Radicut. Transl Stroke Res (2011) 0.92
Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line. Toxicol Sci (2011) 0.92
TRPV1-dependent and -independent alterations in the limbic cortex of neuropathic mice: impact on glial caspases and pain perception. Cereb Cortex (2011) 0.91
Exploring key orientations at protein-protein interfaces with small molecule probes. J Am Chem Soc (2012) 0.90
Acquisition of an olfactory associative task triggers a regionalized down-regulation of adult born neuron cell death. Front Neurosci (2011) 0.89
Combination of intracortically administered VEGF and environmental enrichment enhances brain protection in developing rats. J Neural Transm (Vienna) (2010) 0.88
NMDA receptors and BAX are essential for Aβ impairment of LTP. Sci Rep (2012) 0.88
In vivo evidence that TRAF4 is required for central nervous system myelin homeostasis. PLoS One (2012) 0.88
Caspases cleave and inhibit the microRNA processing protein DiGeorge Critical Region 8. Protein Sci (2012) 0.88
Insulin-like growth factor receptor-1 and nuclear factor κB are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation. J Biol Chem (2012) 0.88
Lateral intracerebroventricular injection of Apelin-13 inhibits apoptosis after cerebral ischemia/reperfusion injury. Neural Regen Res (2015) 0.87
Drosophila spaghetti and doubletime link the circadian clock and light to caspases, apoptosis and tauopathy. PLoS Genet (2015) 0.85
Exposure of neonatal rats to alcohol has differential effects on neuroinflammation and neuronal survival in the cerebellum and hippocampus. J Neuroinflammation (2015) 0.85
Developing a powerful in silico tool for the discovery of novel caspase-3 substrates: a preliminary screening of the human proteome. BMC Bioinformatics (2012) 0.84
Tunneling-nanotube direction determination in neurons and astrocytes. Cell Death Dis (2012) 0.83
Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways. Physiol Genomics (2013) 0.82
Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells. J Pharm Pharmacol (2012) 0.82
Ex vivo imaging of active caspase 3 by a FRET-based molecular probe demonstrates the cellular dynamics and localization of the protease in cerebellar granule cells and its regulation by the apoptosis-inhibiting protein survivin. Mol Neurodegener (2016) 0.82
Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine. Sci Rep (2015) 0.81
Altered processing of amyloid precursor protein in cells undergoing apoptosis. PLoS One (2013) 0.81
Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord. PLoS One (2012) 0.81
The non-death role of metacaspase proteases. Front Oncol (2012) 0.81
Mature and precursor brain-derived neurotrophic factor have individual roles in the mouse olfactory bulb. PLoS One (2012) 0.81
Erythropoietin improved cognitive function and decreased hippocampal caspase activity in rat pups after traumatic brain injury. J Neurotrauma (2014) 0.80
Degeneration of axotomized projection neurons in the rat dLGN: temporal progression of events and their mitigation by a single administration of FGF2. PLoS One (2012) 0.80
microRNA-128a dysregulation in transgenic Huntington's disease monkeys. Mol Brain (2014) 0.80
Alpha II Spectrin breakdown products in immature Sprague Dawley rat hippocampus and cortex after traumatic brain injury. Brain Res (2014) 0.80
Zinc deficiency and neurodevelopment: the case of neurons. Biofactors (2010) 0.80
Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol (2016) 0.79
Global proteomics analysis of testis and ovary in adult zebrafish (Danio rerio). Fish Physiol Biochem (2011) 0.79
Neuroprotective effect of penehyclidine hydrochloride on focal cerebral ischemia-reperfusion injury. Neural Regen Res (2013) 0.79
Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid. J Biomed Sci (2013) 0.79
High expression of long intervening non-coding RNA OLMALINC in the human cortical white matter is associated with regulation of oligodendrocyte maturation. Mol Brain (2015) 0.78
Brain-derived neurotrophic factor prevents dendritic retraction of adult mouse retinal ganglion cells. Eur J Neurosci (2016) 0.78
Modulation of hippocampal neuroplasticity by Fas/CD95 regulatory protein 2 (Faim2) in the course of bacterial meningitis. J Neuropathol Exp Neurol (2014) 0.78
Isolation and chemopreventive evaluation of novel naphthoquinone compounds from Alkanna tinctoria. Anticancer Drugs (2013) 0.78
Caspase inhibition in select olfactory neurons restores innate attraction behavior in aged Drosophila. PLoS Genet (2014) 0.78
Differentially expressed genes in hypothalamus in relation to genomic regions under selection in two chicken lines resulting from divergent selection for high or low body weight. Neurogenetics (2011) 0.78
New insight into the molecular mechanisms of the biological effects of DNA minor groove binders. PLoS One (2011) 0.77
Divergent modulation of neuronal differentiation by caspase-2 and -9. PLoS One (2012) 0.77
De-Risking of Stilbazulenyl Nitrone (STAZN), a Lipophilic Nitrone to Treat Stroke Using a Unique Panel of In Vitro Assays. Transl Stroke Res (2011) 0.77
Cannabinoid mitigation of neuronal morphological change important to development and learning: insight from a zebra finch model of psychopharmacology. Life Sci (2012) 0.77
Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia. Front Pharmacol (2017) 0.77
Intestinal ischemic preconditioning reduces liver ischemia reperfusion injury in rats. Mol Med Rep (2016) 0.76
MKP-1 antagonizes C/EBPβ activity and lowers the apoptotic threshold after ischemic injury. Cell Death Differ (2012) 0.76
Effects of microRNA-21 and microRNA-24 inhibitors on neuronal apoptosis in ischemic stroke. Am J Transl Res (2016) 0.75
Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant. Am J Hum Genet (2016) 0.75
Effects of sufentanil on human gastric cancer cell line SGC-7901 in vitro. Cent Eur J Immunol (2014) 0.75
Exposure to Mixtures of Metals and Neurodevelopmental Outcomes: A Multidisciplinary Review Using an Adverse Outcome Pathway Framework. Risk Anal (2015) 0.75
Toward developing recombinant gonadotropin-based hormone therapies for increasing fertility in the flatfish Senegalese sole. PLoS One (2017) 0.75
Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease. J Alzheimers Dis (2016) 0.75
ScreenCap3: Improving prediction of caspase-3 cleavage sites using experimentally verified noncleavage sites. Proteomics (2014) 0.75
Prolonged expression of Puma in cholinergic amacrine cells during the development of rat retina. J Histochem Cytochem (2012) 0.75
Evodiamine inhibits proliferation and induces apoptosis in gastric cancer cells. Oncol Lett (2015) 0.75
J-147 a Novel Hydrazide Lead Compound to Treat Neurodegeneration: CeeTox(™) Safety and Genotoxicity Analysis. J Neurol Neurophysiol (2013) 0.75
Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc Natl Acad Sci U S A (2016) 0.75
DNA damage precedes apoptosis during the regression of the interdigital tissue in vertebrate embryos. Sci Rep (2016) 0.75
Intratracheal transplantation of mesenchymal stem cells simultaneously attenuates both lung and brain injuries in hyperoxic newborn rats. Pediatr Res (2016) 0.75
Analysis of sequence data to identify potential risk variants for oral clefts in multiplex families. Mol Genet Genomic Med (2017) 0.75
Acute administration of methionine and/or methionine sulfoxide impairs redox status and induces apoptosis in rat cerebral cortex. Metab Brain Dis (2017) 0.75
Apaf-1 is a transcriptional target for E2F and p53. Nat Cell Biol (2001) 2.96
Interdigital cell death can occur through a necrotic and caspase-independent pathway. Curr Biol (1999) 2.11
Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death Differ (2002) 1.85
Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development (2000) 1.77
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. J Cell Biol (2001) 1.24
Maize polyamine oxidase: primary structure from protein and cDNA sequencing. FEBS Lett (1998) 1.14
Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response. Cell Death Differ (2012) 1.08
Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins. Cell Death Differ (2012) 1.02
Apoptosome inactivation rescues proneural and neural cells from neurodegeneration. Cell Death Differ (2004) 0.98
Speciation study of the anti-inflammatory drug tenoxicam (Htenox) with Cu(II): X-ray crystal structure of [Cu(tenox)(2)(py)(2)].EtOH. J Inorg Biochem (2003) 0.89
Physiological and pathological roles of Apaf1 and the apoptosome. J Cell Mol Med (2003) 0.88
Sequence of the gene coding for ribosomal protein S8 of Xenopus laevis. Gene (1993) 0.88
The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage. Cell Death Differ (2010) 0.85
Structure and expression of ribosomal protein genes in Xenopus laevis. Biochem Cell Biol (1996) 0.85
Expression of Foxb1 reveals two strategies for the formation of nuclei in the developing ventral diencephalon. Dev Neurosci (2000) 0.83
Fugu intron oversize reveals the presence of U15 snoRNA coding sequences in some introns of the ribosomal protein S3 gene. Genome Res (1996) 0.82
Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent caspase-3 activation in proneural cells. Cell Mol Life Sci (2008) 0.82
A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2. Cell Death Differ (2010) 0.81
Clinical outcome of sacral neuromodulation in incomplete spinal cord-injured patients suffering from neurogenic bowel dysfunctions. Spinal Cord (2009) 0.80
Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture. Scand J Immunol (2002) 0.77
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Cell Death Differ (2015) 0.77
The fork head transcription factor Fkh5/Mf3 is a developmental marker gene for superior colliculus layers and derivatives of the hindbrain somatic afferent zone. Brain Res Dev Brain Res (1999) 0.77
Apaf1 reduced expression levels generate a mutant phenotype in adult brain and skeleton. Cell Death Differ (2002) 0.75
Sexual life of males over 50 years of age with spinal-cord lesions of at least 20 years. Spinal Cord (2008) 0.75
[Pyloric muscular hypertrophy in the adult]. Chir Ital (1965) 0.75
Beryllium(II) complexes of the Kläui tripodal ligand cyclopentadienyltris(diethylphosphito-p)cobaltate(-). Inorg Chem (2001) 0.75
Cloning and characterization of the European seabass, Dicentrarchus labrax, mitochondrial genome. Curr Genet (1994) 0.75
[Residual cystic stump and its pathology in the so-called post-cholecystectomy syndrome]. Chir Patol Sper (1964) 0.75