Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection.

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Published in Proc Natl Acad Sci U S A on September 28, 2016

Authors

Joseph J Maciag1, Sarah H Mackenzie2, Matthew B Tucker2, Joshua L Schipper2, Paul Swartz2, A Clay Clark3

Author Affiliations

1: Department of Biology, University of Texas at Arlington, Arlington, TX 76019; Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC 27695.
2: Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC 27695.
3: Department of Biology, University of Texas at Arlington, Arlington, TX 76019; Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC 27695; Center for Comparative Medicine and Translational Research, North Carolina State University, Raleigh, NC 27695 clay.clark@uta.edu.

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