Published in J Exp Med on December 07, 2009
Diversity and dialogue in immunity to helminths. Nat Rev Immunol (2011) 3.72
Intestinal goblet cells and mucins in health and disease: recent insights and progress. Curr Gastroenterol Rep (2010) 2.93
An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection. Nat Med (2012) 2.60
Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway. J Exp Med (2010) 2.54
Regulators of Gut Motility Revealed by a Gnotobiotic Model of Diet-Microbiome Interactions Related to Travel. Cell (2015) 2.26
Helminth infections and host immune regulation. Clin Microbiol Rev (2012) 2.02
Muc5ac: a critical component mediating the rejection of enteric nematodes. J Exp Med (2011) 1.88
Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion. Nat Immunol (2014) 1.86
Depletion of murine intestinal microbiota: effects on gut mucosa and epithelial gene expression. PLoS One (2011) 1.74
Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia. Mucosal Immunol (2010) 1.61
Type 2 cytokines: mechanisms and therapeutic strategies. Nat Rev Immunol (2015) 1.57
Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. J Exp Med (2012) 1.49
Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis. Microbiome (2015) 1.39
Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population. Immunity (2012) 1.34
Susceptibility and immunity to helminth parasites. Curr Opin Immunol (2012) 1.26
Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair. Immunity (2015) 1.26
IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms. Proc Natl Acad Sci U S A (2012) 1.19
To B or not to B: B cells and the Th2-type immune response to helminths. Trends Immunol (2010) 1.16
Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins. J Proteomics (2011) 1.16
Helminthic therapy: improving mucosal barrier function. Trends Parasitol (2012) 1.06
Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus. Semin Immunopathol (2012) 1.06
Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection. Immunol Cell Biol (2014) 1.03
Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon. Mucosal Immunol (2014) 1.03
Immunity to gastrointestinal nematodes: mechanisms and myths. Immunol Rev (2014) 1.02
Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus. Eur J Immunol (2012) 1.00
Type 2 innate immunity in helminth infection is induced redundantly and acts autonomously following CD11c(+) cell depletion. Infect Immun (2012) 0.97
Resistin-like molecule α promotes pathogenic Th17 cell responses and bacterial-induced intestinal inflammation. J Immunol (2013) 0.96
Nippostrongylus-induced intestinal hypercontractility requires IL-4 receptor alpha-responsiveness by T cells in mice. PLoS One (2012) 0.94
Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion. J Biol Chem (2011) 0.94
Immune and genetic gardening of the intestinal microbiome. FEBS Lett (2014) 0.91
Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis. Respir Res (2012) 0.91
Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. PLoS Pathog (2015) 0.90
Genetically determined epithelial dysfunction and its consequences for microflora-host interactions. Cell Mol Life Sci (2011) 0.90
A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae. PLoS Negl Trop Dis (2013) 0.87
IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection. Mucosal Immunol (2016) 0.87
IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia. Exp Parasitol (2015) 0.87
TGF-β-responsive myeloid cells suppress type 2 immunity and emphysematous pathology after hookworm infection. Am J Pathol (2012) 0.87
IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection. PLoS Pathog (2013) 0.86
Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation. PLoS Pathog (2015) 0.86
Role of basophils in protective immunity to parasitic infections. Semin Immunopathol (2016) 0.85
Macrophage proliferation, provenance, and plasticity in macroparasite infection. Immunol Rev (2014) 0.85
Mucosal immune responses following intestinal nematode infection. Parasite Immunol (2014) 0.85
Conditional IL-4/IL-13-deficient mice reveal a critical role of innate immune cells for protective immunity against gastrointestinal helminths. Mucosal Immunol (2014) 0.84
Alternatively Activated Macrophages Revisited: New Insights into the Regulation of Immunity, Inflammation and Metabolic Function following Parasite Infection. Curr Immunol Rev (2013) 0.84
Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion. Proc Natl Acad Sci U S A (2014) 0.84
Nematode modulation of inflammatory bowel disease. Protoplasma (2011) 0.83
Development of CD4 T Cell Dependent Immunity Against N. brasiliensis Infection. Front Immunol (2013) 0.83
IL-4Rα-associated antigen processing by B cells promotes immunity in Nippostrongylus brasiliensis infection. PLoS Pathog (2013) 0.83
Non-traditional cytokines: How catecholamines and adipokines influence macrophages in immunity, metabolism and the central nervous system. Cytokine (2015) 0.82
Effects of resistin-like molecule β over-expression on gastric cancer cells in vitro. World J Gastroenterol (2012) 0.82
Acidic chitinase primes the protective immune response to gastrointestinal nematodes. Nat Immunol (2016) 0.82
Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells. J Immunol (2016) 0.81
Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity. PLoS One (2014) 0.81
Requirement for core 2 O-glycans for optimal resistance to helminth infection. PLoS One (2013) 0.81
FIZZ1 could enhance the angiogenic ability of rat aortic endothelial cells. Int J Clin Exp Pathol (2013) 0.81
Hsp12.6 expression is inducible by host immunity in adult worms of the parasitic nematode Nippostrongylus brasiliensis. PLoS One (2011) 0.81
Role of macrophages in the altered epithelial function during a type 2 immune response induced by enteric nematode infection. PLoS One (2014) 0.81
Therapeutic activity of an interleukin-4/interleukin-13 dual antagonist on oxazolone-induced colitis in mice. Immunology (2014) 0.80
Autophagy Protects against Colitis by the Maintenance of Normal Gut Microflora and Secretion of Mucus. J Biol Chem (2015) 0.79
Selenoprotein Expression in Macrophages Is Critical for Optimal Clearance of Parasitic Helminth Nippostrongylus brasiliensis. J Biol Chem (2015) 0.78
Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice. Sci Rep (2016) 0.77
Control of Giardiasis by Interleukin-17 in Humans and Mice-Are the Questions All Answered? Clin Vaccine Immunol (2015) 0.77
Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance. Infect Immun (2016) 0.77
Eosinophils in Helminth Infection: Defenders and Dupes. Trends Parasitol (2016) 0.76
Trefoil factor 2 negatively regulates type 1 immunity against Toxoplasma gondii. J Immunol (2012) 0.76
Critical Role for Interleukin-25 in Host Protective Th2 Memory Response against Heligmosomoides polygyrus bakeri. Infect Immun (2016) 0.76
Selenium status alters the immune response and expulsion of adult Heligmosomoides bakeri worms in mice. Infect Immun (2013) 0.76
Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection. Infect Immun (2016) 0.76
Mina: a Th2 response regulator meets TGFβ. Curr Opin Immunol (2014) 0.76
Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections. Parasite Immunol (2015) 0.75
Homeostasis of the Gut Barrier and Potential Biomarkers. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlβ (RELMβ) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility. Am J Pathol (2016) 0.75
IL-9 and Th9 in parasite immunity. Semin Immunopathol (2016) 0.75
Myeloid-Restricted AMPKα1 Promotes Host Immunity and Protects against IL-12/23p40-Dependent Lung Injury during Hookworm Infection. J Immunol (2016) 0.75
Resistin-Like Molecule-β Promotes Invasion and Migration of Gastric Carcinoma Cells. Med Sci Monit (2016) 0.75
Intestinal tuft cells: epithelial sentinels linking luminal cues to the immune system. Mucosal Immunol (2016) 0.75
Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4(+) T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis. Infect Immun (2017) 0.75
Surfactant Protein-D Is Essential for Immunity to Helminth Infection. PLoS Pathog (2016) 0.75
Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic. Cell Host Microbe (2017) 0.75
Negative Regulation of Type 2 Immunity. Trends Immunol (2017) 0.75
Schistosoma japonicum infection downregulates house dust mite-induced allergic airway inflammation in mice. PLoS One (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity (2004) 6.46
Protective immune mechanisms in helminth infection. Nat Rev Immunol (2007) 5.66
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med (2006) 5.35
Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis. Nature (2007) 4.68
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med (2002) 4.65
Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models. Annu Rev Immunol (1997) 4.22
Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat Med (2006) 4.16
Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J Exp Med (2006) 4.11
Specific assays for cytokine production by T cells. J Immunol Methods (1989) 3.55
Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion. Science (2005) 3.32
IL-33, a potent inducer of adaptive immunity to intestinal nematodes. J Immunol (2008) 3.31
Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J Immunol (1993) 3.29
RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract. Proc Natl Acad Sci U S A (2004) 3.05
Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice. Proc Natl Acad Sci U S A (1991) 3.01
Cytokine-mediated regulation of chronic intestinal helminth infection. J Exp Med (1994) 2.90
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13. Immunity (2002) 2.83
Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung. J Exp Med (2009) 2.51
Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain. Nat Immunol (2007) 2.50
Dependence of IL-4, IL-13, and nematode-induced alterations in murine small intestinal smooth muscle contractility on Stat6 and enteric nerves. J Immunol (2003) 2.27
Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology (2008) 2.09
Retnla (relmalpha/fizz1) suppresses helminth-induced Th2-type immunity. PLoS Pathog (2009) 2.07
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med (2008) 1.83
Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. J Allergy Clin Immunol (2006) 1.79
Disulfide-dependent multimeric assembly of resistin family hormones. Science (2004) 1.76
Development of an assay to measure in vivo cytokine production in the mouse. Int Immunol (1999) 1.68
The role of IL-4 in Heligmosomoides polygyrus-induced alterations in murine intestinal epithelial cell function. J Immunol (2001) 1.56
Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell- and T cell-dependent mechanism. J Immunol (2000) 1.52
Human intestinal epithelial cells express functional cytokine receptors sharing the common gamma c chain of the interleukin 2 receptor. Proc Natl Acad Sci U S A (1995) 1.45
IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice. J Immunol (1995) 1.43
Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation. J Immunol (2008) 1.41
Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma. J Immunol (2004) 1.38
Cutting edge: IL-4 receptor expression by non-bone marrow-derived cells is required to expel gastrointestinal nematode parasites. J Immunol (2001) 1.34
IL-4 exacerbates anaphylaxis. J Immunol (2003) 1.34
Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses. J Immunol (2007) 1.29
In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity. Cell Immunol (1985) 1.15
Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in SMC-specific IL-4Ralpha-deficient mice. PLoS Pathog (2007) 1.12
Molting, ecdysis, and reproduction of Trichinella spiralis are supported in vitro by intestinal epithelial cells. Infect Immun (2002) 1.11
Nippostrongylus brasiliensis: reversibility of reduced-energy status associated with the course of expulsion from the small intestine in rats. Exp Parasitol (2007) 1.05
Molecular mechanisms underlying IL-4-induced leukocyte recruitment in vivo: a critical role for the alpha 4 integrin. J Immunol (1999) 1.05
Endogenously produced IL-4 nonredundantly stimulates CD8+ T cell proliferation. J Immunol (2009) 1.03
Genetic and immunological adaptation of Heligmosomoides polygyrus in mice. Int J Parasitol (1997) 0.83
Intestinal distribution of worms and host ingesta in Nippostrongylus brasiliensis. J Parasitol (2001) 0.79
Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol (2011) 12.48
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature (2007) 11.59
Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology (2007) 9.05
Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science (2011) 8.53
The eosinophil. Annu Rev Immunol (2006) 7.06
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest (2006) 6.61
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity (2004) 6.46
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. Dev Cell (2002) 6.41
A promoter-level mammalian expression atlas. Nature (2014) 6.25
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
Protective immune mechanisms in helminth infection. Nat Rev Immunol (2007) 5.66
Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J Clin Invest (2006) 5.48
Trichuris suis therapy for active ulcerative colitis: a randomized controlled trial. Gastroenterology (2005) 5.26
IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses. Nature (2010) 5.07
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature (2011) 4.71
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med (2004) 4.45
Eosinophilic esophagitis. N Engl J Med (2004) 4.43
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol (2004) 4.41
Interleukin-17 is a negative regulator of established allergic asthma. J Exp Med (2006) 4.38
Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nat Med (2006) 4.16
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest (2003) 4.08
Eosinophils: biological properties and role in health and disease. Clin Exp Allergy (2008) 3.92
Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J Leukoc Biol (2002) 3.89
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. J Allergy Clin Immunol (2009) 3.74
IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med (2007) 3.69
A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. Gastroenterology (2006) 3.68
Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites. Immunol Rev (2004) 3.63
Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis. J Allergy Clin Immunol (2006) 3.51
Comparative dietary therapy effectiveness in remission of pediatric eosinophilic esophagitis. J Allergy Clin Immunol (2012) 3.45
Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel disease. Am J Gastroenterol (2003) 3.40
The IL-21 receptor augments Th2 effector function and alternative macrophage activation. J Clin Invest (2006) 3.33
Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection. J Immunol (2007) 3.25
IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids. J Allergy Clin Immunol (2007) 3.24
Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. J Allergy Clin Immunol (2006) 3.04
MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. J Immunol (2009) 2.89
Refining the definition of hypereosinophilic syndrome. J Allergy Clin Immunol (2010) 2.74
Intestinal barrier function: molecular regulation and disease pathogenesis. J Allergy Clin Immunol (2009) 2.63
An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection. Nat Med (2012) 2.60
Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain. Nat Immunol (2007) 2.50
Nonredundant roles for B cell-derived IL-10 in immune counter-regulation. J Immunol (2009) 2.48
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans. J Immunol (2007) 2.48
Alternatively activated macrophages in helminth infections. Curr Opin Immunol (2007) 2.41
Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism. Gastroenterology (2003) 2.40
CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature (2009) 2.39
The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma. Immunity (2010) 2.38
Foxa2 regulates alveolarization and goblet cell hyperplasia. Development (2004) 2.35
Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis. J Exp Med (2007) 2.33
Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes. J Allergy Clin Immunol (2003) 2.31
Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J Leukoc Biol (2004) 2.30
Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans. Cell (2004) 2.28
Exposure to schistosome eggs protects mice from TNBS-induced colitis. Am J Physiol Gastrointest Liver Physiol (2002) 2.28
Dependence of IL-4, IL-13, and nematode-induced alterations in murine small intestinal smooth muscle contractility on Stat6 and enteric nerves. J Immunol (2003) 2.27
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J Exp Med (2008) 2.19
Pediatric patients with eosinophilic esophagitis: an 8-year follow-up. J Allergy Clin Immunol (2007) 2.18
Mast cells are required for experimental oral allergen-induced diarrhea. J Clin Invest (2003) 2.17
Unique maturation program of the IgE response in vivo. Immunity (2007) 2.15
The immune response to parasitic helminths: insights from murine models. Trends Immunol (2003) 2.14
Clinical, pathologic, and molecular characterization of familial eosinophilic esophagitis compared with sporadic cases. Clin Gastroenterol Hepatol (2008) 2.12
Structure and genetics of Shigella O antigens. FEMS Microbiol Rev (2008) 2.11
Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology (2008) 2.09
Retnla (relmalpha/fizz1) suppresses helminth-induced Th2-type immunity. PLoS Pathog (2009) 2.07
Computational tools for copy number variation (CNV) detection using next-generation sequencing data: features and perspectives. BMC Bioinformatics (2013) 2.07
IL-5 promotes eosinophil trafficking to the esophagus. J Immunol (2002) 2.06
Chemokines in asthma: cooperative interaction between chemokines and IL-13. J Allergy Clin Immunol (2003) 2.06
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma. J Exp Med (2002) 2.04
Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels. J Allergy Clin Immunol (2008) 2.04
Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development (2004) 2.01
Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999. J Allergy Clin Immunol (2010) 2.00
MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity. J Immunol (2011) 2.00
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1. Nat Med (2012) 1.93
Involvement of mast cells in eosinophilic esophagitis. J Allergy Clin Immunol (2010) 1.92
Heligmosomoides polygyrus inhibits established colitis in IL-10-deficient mice. Eur J Immunol (2004) 1.92
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells. Immunity (2002) 1.89
Tracing the origin and history of HIV-1 subtype B' epidemic by near full-length genome analyses. AIDS (2012) 1.89
Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. Clin Gastroenterol Hepatol (2004) 1.87
Importance of cytokines in murine allergic airway disease and human asthma. J Immunol (2010) 1.86
Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection. J Immunol (2005) 1.86
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. J Immunol (2010) 1.85
Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung. Am J Physiol Lung Cell Mol Physiol (2007) 1.85
Pathways of anaphylaxis in the mouse. J Allergy Clin Immunol (2002) 1.84
Potential of blood eosinophils, eosinophil-derived neurotoxin, and eotaxin-3 as biomarkers of eosinophilic esophagitis. Clin Gastroenterol Hepatol (2006) 1.84
Peanuts can contribute to anaphylactic shock by activating complement. J Allergy Clin Immunol (2009) 1.84
A striking local esophageal cytokine expression profile in eosinophilic esophagitis. J Allergy Clin Immunol (2011) 1.82