MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression.

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Published in J Immunol on April 15, 2009

Authors

Thomas X Lu1, Ariel Munitz, Marc E Rothenberg

Author Affiliations

1: Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.

Associated clinical trials:

Epigenetic Regulation of Exercise Induced Asthma | NCT05174689

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The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity. Nat Med (2013) 1.20

Arginine in asthma and lung inflammation. J Nutr (2004) 1.19

Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma. Am J Respir Cell Mol Biol (2004) 1.19

Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G). Genomics (2003) 1.18

Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9). Proc Natl Acad Sci U S A (2004) 1.18

Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry. J Pediatr (2002) 1.17

The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells. J Immunol (2005) 1.15

Suppressive effect of IL-4 on IL-13-induced genes in mouse lung. J Immunol (2005) 1.14

Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity. J Allergy Clin Immunol (2003) 1.13

Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). J Allergy Clin Immunol (2012) 1.12

Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases. J Allergy Clin Immunol (2013) 1.11

Expression and regulation of small proline-rich protein 2 in allergic inflammation. Am J Respir Cell Mol Biol (2005) 1.11

Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity. J Agric Food Chem (2005) 1.11