Published in J Org Chem on January 15, 2010
Transition metal-mediated synthesis of monocyclic aromatic heterocycles. Chem Rev (2013) 0.92
Recent advances in the gold-catalyzed additions to C-C multiple bonds. Beilstein J Org Chem (2011) 0.79
Isotopic labelling studies for a gold-catalysed skeletal rearrangement of alkynyl aziridines. Beilstein J Org Chem (2011) 0.77
Small molecule regulators of autophagy identified by an image-based high-throughput screen. Proc Natl Acad Sci U S A (2007) 3.37
Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (2013) 3.17
Interface-induced superconductivity and strain-dependent spin density waves in FeSe/SrTiO3 thin films. Nat Mater (2013) 2.15
COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature (2012) 2.11
Preoperative alpha blockade for normotensive pheochromocytoma: is it necessary? J Hypertens (2011) 1.50
Microsurgical anatomy of the greater superficial petrosal nerve. World Neurosurg (2011) 1.45
Novel mutations of the FRMD7 gene in X-linked congenital motor nystagmus. Mol Vis (2007) 1.45
A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice. Proc Natl Acad Sci U S A (2007) 1.43
COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A (2010) 1.43
A robust homogeneous binding assay for alpha4beta2 nicotinic acetylcholine receptor. Acta Pharmacol Sin (2005) 1.43
The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism. Cell Metab (2009) 1.38
COUP-TFs regulate eye development by controlling factors essential for optic vesicle morphogenesis. Development (2010) 1.23
Tools for GPCR drug discovery. Acta Pharmacol Sin (2012) 1.22
Gold-catalyzed multicomponent synthesis of aminoindolizines from aldehydes, amines, and alkynes under solvent-free conditions or in water. Org Lett (2007) 1.21
HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9. Brain Res (2011) 1.14
Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells. Cell Res (2011) 1.13
Antiasthmatic drugs targeting the cysteinyl leukotriene receptor 1 alleviate central nervous system inflammatory cell infiltration and pathogenesis of experimental autoimmune encephalomyelitis. J Immunol (2011) 1.11
Highly efficient synthesis of functionalized indolizines and indolizinones by copper-catalyzed cycloisomerizations of propargylic pyridines. J Org Chem (2007) 1.11
Bone morphogenetic protein-4 mediates cardiac hypertrophy, apoptosis, and fibrosis in experimentally pathological cardiac hypertrophy. Hypertension (2012) 1.08
Structural characterization of full-length NSF and 20S particles. Nat Struct Mol Biol (2012) 1.08
Enhanced susceptibility to kainate-induced seizures, neuronal apoptosis, and death in mice lacking gangliotetraose gangliosides: protection with LIGA 20, a membrane-permeant analog of GM1. J Neurosci (2005) 1.04
Blocking A2B adenosine receptor alleviates pathogenesis of experimental autoimmune encephalomyelitis via inhibition of IL-6 production and Th17 differentiation. J Immunol (2012) 1.02
Establishment of an ELISA system for determining soluble LAIR-1 levels in sera of patients with HFRS and kidney transplant. J Immunol Methods (2004) 0.98
Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin. Oncol Rep (2013) 0.96
The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis. J Biol Chem (2012) 0.94
Novel object recognition as a facile behavior test for evaluating drug effects in AβPP/PS1 Alzheimer's disease mouse model. J Alzheimers Dis (2012) 0.92
GPNMB enhances bone regeneration by promoting angiogenesis and osteogenesis: potential role for tissue engineering bone. J Cell Biochem (2013) 0.92
Proliferation rate of somatic cells affects reprogramming efficiency. J Biol Chem (2013) 0.92
Stereospecific induction of nuclear factor-kappaB activation by isochamaejasmin. Mol Pharmacol (2005) 0.91
Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum. Proc Natl Acad Sci U S A (2009) 0.91
Role of Src in ligand-specific regulation of delta-opioid receptor desensitization and internalization. J Neurochem (2008) 0.91
Rapid discrimination and quantification of alkaloids in Corydalis Tuber by near-infrared spectroscopy. J Pharm Biomed Anal (2011) 0.90
Stress-mediated p38 activation promotes somatic cell reprogramming. Cell Res (2012) 0.90
G protein-coupled receptors as therapeutic targets for multiple sclerosis. Cell Res (2012) 0.90
Urinary TNF-α and NGAL are correlated with the progression of nephropathy in patients with type 2 diabetes. Exp Ther Med (2013) 0.89
iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery. Acta Pharmacol Sin (2013) 0.89
Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and LIGA20. Glycoconj J (2004) 0.89
Bromfenac sodium 0.1%, fluorometholone 0.1% and dexamethasone 0.1% for control of ocular inflammation and prevention of cystoid macular edema after phacoemulsification. Ophthalmologica (2013) 0.88
(4-[6-(4-isopropoxyphenyl)pyrazolo [1,5-a]pyrimidin-3-yl] quinoline) is a novel inhibitor of autophagy. Br J Pharmacol (2014) 0.88
Lipopolysaccharide up-regulates the expression of Fcalpha/mu receptor and promotes the binding of oxidized low-density lipoprotein and its IgM antibody complex to activated human macrophages. Atherosclerosis (2009) 0.88
Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR. Mol Pharmacol (2007) 0.87
Silencing of GPNMB by siRNA inhibits the formation of melanosomes in melanocytes in a MITF-independent fashion. PLoS One (2012) 0.86
Significance of heparanase-1 and vascular endothelial growth factor in adrenocortical carcinoma angiogenesis: potential for therapy. Endocrine (2011) 0.85
The immunosuppressant cyclosporin A antagonizes human formyl peptide receptor through inhibition of cognate ligand binding. J Immunol (2006) 0.84
Toll-like receptor-9 induced by physical trauma mediates release of cytokines following exposure to CpG motif in mouse skin. Immunology (2003) 0.83
Characterization of cholera toxin B subunit-induced Ca(2+) influx in neuroblastoma cells: evidence for a voltage-independent GM1 ganglioside-associated Ca(2+) channel. J Neurosci Res (2002) 0.83
Serine 363 of the {delta}-opioid receptor is crucial for adopting distinct pathways to activate ERK1/2 in response to stimulation with different ligands. J Cell Sci (2010) 0.83
Podophyllotoxin induces CREB phosphorylation and CRE-driven gene expression via PKA but not MAPKs. Mol Cells (2009) 0.83
Bryostatin-5 blocks stromal cell-derived factor-1 induced chemotaxis via desensitization and down-regulation of cell surface CXCR4 receptors. Cancer Res (2008) 0.82
Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis. J Cell Physiol (2014) 0.82
Artesunate induces G2/M cell cycle arrest through autophagy induction in breast cancer cells. Anticancer Drugs (2014) 0.82
Lateral photovoltaic effect and electron transport observed in Cr nano-film. Opt Express (2014) 0.82
Development of a universal high-throughput calcium assay for G-protein- coupled receptors with promiscuous G-protein Galpha15/16. Acta Pharmacol Sin (2008) 0.81
Engineering tubular bone using mesenchymal stem cell sheets and coral particles. Biochem Biophys Res Commun (2013) 0.81
A novel therapeutic drug for colon cancer: EpCAM scFv-truncated protamine (tp)-siRNA. Cell Biol Int (2013) 0.81
The expression, regulation and adhesion function of a novel CD molecule, CD226, on human endothelial cells. Life Sci (2003) 0.81
Improved synthesis of aryl-substituted anthracenes and heteroacenes. J Org Chem (2007) 0.80
Glucagon receptor mediates calcium signaling by coupling to G alpha q/11 and G alpha i/o in HEK293 cells. J Recept Signal Transduct Res (2009) 0.80
Permeability and concentration of levofloxacin in epithelial lining fluid in patients with lower respiratory tract infections. J Clin Pharmacol (2009) 0.80
Palladium-catalyzed highly efficient synthesis of tetracenes and pentacenes. Chem Commun (Camb) (2012) 0.80
A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and β-arrestin 1. Diabetologia (2014) 0.80
Curcumin inhibits hERG potassium channels in vitro. Toxicol Lett (2011) 0.80
Organocatalytic tandem Morita-Baylis-Hillman-Michael reaction for asymmetric synthesis of a drug-like oxa-spirocyclic indanone scaffold. Chem Commun (Camb) (2013) 0.80
A facile Zr-mediated multicomponent approach to arylated allylic alcohols and its application to the synthesis of highly substituted indenes and spiroindenes. Org Biomol Chem (2008) 0.79
Preparation and evaluation of hydrophilic C18 monolithic sorbents for enhanced polar compound retention in liquid chromatography and solid phase extraction. J Chromatogr A (2011) 0.79
Gold-catalyzed cascade Friedel-Crafts/furan-alkyne cycloisomerizations for the highly efficient synthesis of arylated (Z)-enones or -enals. Org Lett (2009) 0.79
Development of a high-throughput assay for screening of gamma-secretase inhibitor with endogenous human, mouse or Drosophila gamma-secretase. Molecules (2009) 0.79
Application of the soluble salt-assisted route to scalable synthesis of ZnO nanopowder with repeated photocatalytic activity. Nanotechnology (2012) 0.79
A cell-based high-throughput assay for the screening of small-molecule inhibitors of p53-MDM2 interaction. J Biomol Screen (2011) 0.79
Development of a quantitative, cell-based, high-content screening assay for epidermal growth factor receptor modulators. Acta Pharmacol Sin (2007) 0.78
Fabrication and characterization of nuclear localization signal-conjugated glycol chitosan micelles for improving the nuclear delivery of doxorubicin. Int J Nanomedicine (2012) 0.78
Gold-catalyzed efficient synthesis of 2,4-disubstituted furans from aryloxy-enynes. Org Biomol Chem (2012) 0.78
[Application of Metaphase-Fluorescence in Situ Hybridization to the Diagnosis of Acute Promyelocytic Leukemia and the Detection of Minimal Residual Disease] Zhongguo Shi Yan Xue Ye Xue Za Zhi (2000) 0.78
Induction of matrix metalloproteinase-3 (MMP-3) expression in the microglia by lipopolysaccharide (LPS) via upregulation of glycoprotein nonmetastatic melanoma B (GPNMB) expression. J Mol Neurosci (2014) 0.78
Gold-catalyzed oxidative rearrangement involving 1,2-acyl migration: efficient synthesis of functionalized dihydro-γ-carbolines from α-(2-indolyl) propargylic alcohols and imines. Angew Chem Int Ed Engl (2013) 0.78
Comparative proteomic analyses reveal that the regulators of G-protein signaling proteins regulate amino acid metabolism of the rice blast fungus Magnaporthe oryzae. Proteomics (2014) 0.78
Synthesis and SAR study of opioid receptor ligands: mono- and bis-indolomorphinans. Chem Biol Drug Des (2009) 0.78
Structural optimization and biological evaluation of substituted bisphenol A derivatives as beta-amyloid peptide aggregation inhibitors. J Med Chem (2010) 0.78
Magnesium Lithospermate B Protects Cardiomyocytes from Ischemic Injury Via Inhibition of TAB1-p38 Apoptosis Signaling. Front Pharmacol (2010) 0.78
Identification of a novel small-molecule agonist for human G protein-coupled receptor 3. J Pharmacol Exp Ther (2014) 0.77
(Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one sensitizes Escherichia coli persister cells to antibiotics. Appl Microbiol Biotechnol (2013) 0.77
Discovery of a novel CCR5 antagonist lead compound through fragment assembly. Molecules (2008) 0.77
The transcription co-repressor TLE1 interacted with the intracellular region of gpl30 through its Q domain. Mol Cell Biochem (2002) 0.77
Chromium-mediated synthesis of polycyclic aromatic compounds from halobiaryls. Org Lett (2005) 0.77
Gold(I)-catalyzed 1,4- and/or 1,5-heteroaryl migration reactions through regiocontrolled cyclizations. Chemistry (2014) 0.77
Estrogen decreases anoikis of ovarian cancer cell line Caov-3 through reducing release of Bit1. DNA Cell Biol (2014) 0.77
Gold-catalyzed benzannulation of 3-alkoxy-1,5-enynes: access to functionalized benzenes. J Org Chem (2010) 0.77
Facile synthesis of fully substituted dihydro-β-carbolines via Brønsted acid promoted cascade reactions of α-indolyl propargylic alcohols with nitrones. Org Lett (2012) 0.77
Synthesis and opioid receptor activity of indolopropellanes. Bioorg Med Chem Lett (2009) 0.77
Environmentally benign synthesis of indeno[1,2-b]quinolines via an intramolecular Povarov reaction. Org Lett (2013) 0.77
Gold-catalyzed deacylative cycloisomerization reactions of 3-acylindole/ynes: a new approach for carbazole synthesis. Org Lett (2011) 0.77
Gold-catalyzed approach to multisubstituted fulvenes via cycloisomerization of furan/ynes. J Org Chem (2011) 0.77
Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 2: Discovery of highly potent anti-HIV agents. Bioorg Med Chem Lett (2010) 0.77
Human foreskin fibroblast produces interleukin-6 to support derivation and self-renewal of mouse embryonic stem cells. Stem Cell Res Ther (2012) 0.77
Stereoselective synthesis of beta-hydroxyallenes with multiple contiguous stereogenic centers via aldehyde addition to alpha-alkenyl-substituted zirconacyclopentenes. J Org Chem (2009) 0.77
Folic acid conjugated glycol chitosan micelles for targeted delivery of doxorubicin: preparation and preliminary evaluation in vitro. J Biomater Sci Polym Ed (2012) 0.77
Expression of FGF4 mRNA is mediated by mating behaviours in mice. Cell Biochem Funct (2012) 0.77