Joseph C Loftus

Author PubWeight™ 22.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res 2002 2.36
2 Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome. Cancer Res 2006 1.66
3 The tyrosine kinase pyk2 promotes migration and invasion of glioma cells. Neoplasia 2005 1.60
4 Differential role of proline-rich tyrosine kinase 2 and focal adhesion kinase in determining glioblastoma migration and proliferation. Mol Cancer Res 2003 1.10
5 Targeted measles virus vector displaying echistatin infects endothelial cells via alpha(v)beta3 and leads to tumor regression. Cancer Res 2005 1.09
6 Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells. Mol Cancer Res 2012 1.08
7 Tumor necrosis factor-like weak inducer of apoptosis stimulation of glioma cell survival is dependent on Akt2 function. Mol Cancer Res 2009 1.08
8 Targeting Pyk2 for therapeutic intervention. Expert Opin Ther Targets 2010 1.04
9 TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling. Mol Cancer Res 2010 1.03
10 Critical role of the FERM domain in Pyk2 stimulated glioma cell migration. Biochem Biophys Res Commun 2006 0.98
11 Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion. Am J Pathol 2012 0.96
12 Reciprocal activation of transcription factors underlies the dichotomy between proliferation and invasion of glioma cells. PLoS One 2013 0.93
13 Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts. J Neurooncol 2008 0.90
14 A lethal perinatal cardiac phenotype resulting from altered integrin function in cardiomyocytes. J Card Fail 2002 0.89
15 The Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasion via tumor necrosis factor receptor-associated factor 2. J Biol Chem 2013 0.88
16 Differential effects of Pyk2 and FAK on the hypertrophic response of cardiac myocytes. Cell Tissue Res 2009 0.82
17 Structural conservation in band 4.1, ezrin, radixin, moesin (FERM) domains as a guide to identify inhibitors of the proline-rich tyrosine kinase 2. J Med Chem 2010 0.82
18 The Pyk2 FERM regulates Pyk2 complex formation and phosphorylation. Cell Signal 2010 0.80
19 Effects of raloxifene hydrochloride on endometrial cancer cells in vitro. Gynecol Oncol 2004 0.79
20 Differential expression of microRNAs as predictors of glioblastoma phenotypes. BMC Bioinformatics 2014 0.79
21 Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis. J Biol Chem 2013 0.79
22 In vitro selection of fibronectin gain-of-function mutations. Biochem J 2002 0.75
23 A mutation in the integrin alphaIIb subunit that selectively inhibits alphaIIb beta3 receptor function. Thromb Haemost 2003 0.75
24 Many alphaIIbbeta3 autoepitopes in chronic immune thrombocytopenic purpura are localized to alphaIIb between amino acids L1 and Q459. Br J Haematol 2002 0.75