Published in Thromb Res on December 09, 2009
Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials. Cell Host Microbe (2012) 1.16
Molecular characterization of transcriptome-wide interactions between highly pathogenic porcine reproductive and respiratory syndrome virus and porcine alveolar macrophages in vivo. Int J Biol Sci (2011) 1.06
Exposure to acrolein by inhalation causes platelet activation. Toxicol Appl Pharmacol (2010) 0.97
Platelet activation, P-selectin, and eosinophil β1-integrin activation in asthma. Am J Respir Crit Care Med (2012) 0.94
Mechanism of platelet factor 4 (PF4) deficiency with RUNX1 haplodeficiency: RUNX1 is a transcriptional regulator of PF4. J Thromb Haemost (2011) 0.90
The role of platelet factor 4 in radiation-induced thrombocytopenia. Int J Radiat Oncol Biol Phys (2011) 0.87
Serum platelet factor 4 is an independent predictor of survival and venous thromboembolism in patients with pancreatic adenocarcinoma. Cancer Epidemiol Biomarkers Prev (2010) 0.86
Platelets recognize brain-specific glycolipid structures, respond to neurovascular damage and promote neuroinflammation. PLoS One (2013) 0.86
Chebulagic acid inhibits the LPS-induced expression of TNF-α and IL-1β in endothelial cells by suppressing MAPK activation. Exp Ther Med (2015) 0.81
Potential serum biomarkers for glioblastoma diagnostic assessed by proteomic approaches. Proteome Sci (2014) 0.80
An unexpected role for platelets in blocking Th17 differentiation. J Clin Invest (2014) 0.80
Histological and global gene expression analysis of the 'lactating' pigeon crop. BMC Genomics (2011) 0.79
Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage. Br J Pharmacol (2015) 0.79
Alternative C-terminal helix orientation alters chemokine function: structure of the anti-angiogenic chemokine, CXCL4L1. J Biol Chem (2013) 0.79
Platelet factor 4 protects bone marrow mesenchymal stem cells from acute radiation injury. Br J Radiol (2014) 0.78
Differential expression of functional Fc-receptors and additional immune complex receptors on mouse kidney cells. Mol Immunol (2013) 0.77
Low fasting glucose is associated with enhanced thrombin generation and unfavorable fibrin clot properties in type 2 diabetic patients with high cardiovascular risk. Cardiovasc Diabetol (2015) 0.77
New strategy for sepsis: Targeting a key role of platelet-neutrophil interaction. Burns Trauma (2014) 0.77
Intramedullary megakaryocytes internalize released platelet factor 4 and store it in alpha granules. J Thromb Haemost (2015) 0.76
Differential proteomic analysis of virus-enriched fractions obtained from plasma pools of patients with dengue fever or severe dengue. BMC Infect Dis (2015) 0.76
Dealing with prognostic signature instability: a strategy illustrated for cardiovascular events in patients with end-stage renal disease. BMC Med Genomics (2016) 0.75
Intercellular Interactions as Regulators of NETosis. Front Immunol (2016) 0.75
Feasibility of improving platelet-rich plasma therapy by using chitosan with high platelet activation ability. Exp Ther Med (2017) 0.75
Platelet Factor 4 Inhibits and Enhances HIV-1 Infection in a Concentration-Dependent Manner by Modulating Viral Attachment. AIDS Res Hum Retroviruses (2016) 0.75
New insights into the protective power of platelets in malaria infection. Commun Integr Biol (2013) 0.75
The Role of Cytokine PF4 in the Antiviral Immune Response of Shrimp. PLoS One (2016) 0.75
Serum platelet factor 4 is a reliable activity parameter in adult patients with inflammatory bowel disease: A pilot study. Medicine (Baltimore) (2017) 0.75
Plasma peptide biomarker discovery for amyotrophic lateral sclerosis by MALDI-TOF mass spectrometry profiling. PLoS One (2013) 0.75
Comprehensive comparison of neonate and adult human platelet transcriptomes. PLoS One (2017) 0.75
CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection. Immunity (2010) 2.16
Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV. AIDS (2003) 2.12
Platelet factor 4 localization in carotid atherosclerotic plaques: correlation with clinical parameters. Thromb Haemost (2003) 1.91
Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors. EMBO J (2002) 1.84
Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. Blood (2012) 1.72
NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. EMBO J (2009) 1.66
Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia. Blood (2004) 1.63
Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin. Blood (2013) 1.63
Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment. Blood (2003) 1.62
Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications. Blood (2005) 1.59
Dynamic antibody-binding properties in the pathogenesis of HIT. Blood (2012) 1.59
Transgenic mice studies demonstrate a role for platelet factor 4 in thrombosis: dissociation between anticoagulant and antithrombotic effect of heparin. Blood (2004) 1.50
The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy. Blood (2010) 1.40
Infusion of mature megakaryocytes into mice yields functional platelets. J Clin Invest (2010) 1.39
The clinical course and genetic defect in the PCFT gene in a 27-year-old woman with hereditary folate malabsorption. J Pediatr (2008) 1.36
Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications. Blood (2007) 1.34
Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots. Blood (2008) 1.31
Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood (2007) 1.28
Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins. Blood (2006) 1.25
Determinants of PF4/heparin immunogenicity. Blood (2007) 1.25
Megakaryocyte biology and related disorders. J Clin Invest (2005) 1.23
Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets. Blood (2003) 1.18
Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials. Cell Host Microbe (2012) 1.16
Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation. Blood (2010) 1.14
Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype. Blood (2013) 1.11
FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood (2010) 1.09
The relative role of PLCbeta and PI3Kgamma in platelet activation. Blood (2005) 1.09
Challenges and promises for the development of donor-independent platelet transfusions. Blood (2013) 1.09
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. Biochem J (2002) 1.08
In vivo efficacy of platelet-delivered, high specific activity factor VIII variants. Blood (2010) 1.08
Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis. J Pharmacol Exp Ther (2009) 1.05
Diminished adhesion and activation of platelets and neutrophils with CD47 functionalized blood contacting surfaces. Biomaterials (2012) 1.04
Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia. Blood (2010) 1.04
Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells. J Biol Chem (2002) 1.02
Defining a second epitope for heparin-induced thrombocytopenia/thrombosis antibodies using KKO, a murine HIT-like monoclonal antibody. Blood (2002) 1.01
Quinine-dependent, platelet-reactive monoclonals mimic antibodies found in patients with quinine-induced immune thrombocytopenia. Blood (2008) 1.00
Intracellular interaction of von Willebrand factor and factor VIII depends on cellular context: lessons from platelet-expressed factor VIII. Blood (2005) 0.99
Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf. Blood (2012) 0.99
High-level transgene expression in induced pluripotent stem cell-derived megakaryocytes: correction of Glanzmann thrombasthenia. Blood (2013) 0.98
Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection. J Clin Invest (2014) 0.97
Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist. Blood (2009) 0.96
Heparin-induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly. J Clin Apher (2007) 0.95
Identification of distal regulatory regions in the human alpha IIb gene locus necessary for consistent, high-level megakaryocyte expression. Blood (2002) 0.95
Interactions of platelet factor 4 with the vessel wall. Semin Thromb Hemost (2004) 0.94
PF4/heparin complexes are T cell-dependent antigens. Blood (2005) 0.93
Platelet factor 4 regulates megakaryopoiesis through low-density lipoprotein receptor-related protein 1 (LRP1) on megakaryocytes. Blood (2009) 0.93
Efficacy of IVIG affinity-purified anti-double-stranded DNA anti-idiotypic antibodies in the treatment of an experimental murine model of systemic lupus erythematosus. Int Immunol (2002) 0.93
Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice. Blood (2007) 0.93
Species differences in small molecule binding to alpha IIb beta 3 are the result of sequence differences in 2 loops of the alpha IIb beta propeller. Blood (2008) 0.92
Resveratrol protects SH-SY5Y neuroblastoma cells from apoptosis induced by dopamine. Exp Mol Med (2007) 0.92
The role of surface PF4: glycosaminoglycan complexes in the pathogenesis of heparin-induced thrombocytopenia (HIT). Pathophysiol Haemost Thromb (2006) 0.89
The role of platelet factor 4 in radiation-induced thrombocytopenia. Int J Radiat Oncol Biol Phys (2011) 0.87
Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells. J Clin Invest (2015) 0.85
In vivo characterization of the integrin beta3 as a receptor for Hantaan virus cellular entry. Exp Mol Med (2005) 0.85
The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis. J Clin Invest (2015) 0.85
Endogenous platelet factor 4 stimulates activated protein C generation in vivo and improves survival after thrombin or lipopolysaccharide challenge. Blood (2007) 0.84
Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation. Haematologica (2013) 0.83
Development and licensure of medical countermeasures for platelet regeneration after radiation exposure. Radiat Res (2011) 0.81
Targeting recombinant thrombomodulin fusion protein to red blood cells provides multifaceted thromboprophylaxis. Blood (2012) 0.81
Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction. Blood (2011) 0.81
Surface heparinization of polyurethane via bromoalkylation of hard segment nitrogens. Biomacromolecules (2006) 0.81
Mechanisms for mentored career development: the NIH research career awards and other national awards. Hematology Am Soc Hematol Educ Program (2007) 0.77
Modulation of protein C activation by histones, platelet factor 4, and heparinoids: new insights into activated protein C formation. Arterioscler Thromb Vasc Biol (2013) 0.77
Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT. Blood (2011) 0.76
Distinct specificity and single-molecule kinetics characterize the interaction of pathogenic and non-pathogenic antibodies against platelet factor 4-heparin complexes with platelet factor 4. J Biol Chem (2013) 0.76
Atherosclerosis is not a risk factor for anti-platelet factor 4/heparin antibody formation after cardiopulmonary bypass surgery. Thromb Haemost (2014) 0.75
Ectopic platelet-delivered factor (F) VIII for the treatment of Hemophilia A: Plasma and platelet FVIII, is it all the same? J Genet Syndr Gene Ther (2011) 0.75
A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation. J Clin Invest (2016) 0.75
Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia. J Clin Invest (2017) 0.75
Role of monocytes and endothelial cells in heparin-induced thrombocytopenia. Thromb Haemost (2016) 0.75
Current status of blood 'pharming': megakaryoctye transfusions as a source of platelets. Curr Opin Hematol (2017) 0.75