Akitoshi Ishizaka

Author PubWeight™ 129.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2003 8.34
2 High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 2005 5.04
3 Contributions of high mobility group box protein in experimental and clinical acute lung injury. Am J Respir Crit Care Med 2004 2.50
4 Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol 2002 2.30
5 Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, Sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV study. Pulm Pharmacol Ther 2011 2.29
6 HMGB1 contributes to the development of acute lung injury after hemorrhage. Am J Physiol Lung Cell Mol Physiol 2005 2.21
7 Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 2010 2.03
8 Evaluation of pathogen detection from clinical samples by real-time polymerase chain reaction using a sepsis pathogen DNA detection kit. Crit Care 2010 1.81
9 Infusion of the beta-adrenergic blocker esmolol attenuates myocardial dysfunction in septic rats. Crit Care Med 2005 1.73
10 Serum indicators for the diagnosis of pneumocystis pneumonia. Chest 2007 1.73
11 The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury. J Immunol 2009 1.71
12 Physiological and biochemical markers of alveolar epithelial barrier dysfunction in perfused human lungs. Am J Physiol Lung Cell Mol Physiol 2007 1.63
13 Bronchoscopic microsampling method for measuring drug concentration in epithelial lining fluid. Am J Respir Crit Care Med 2003 1.62
14 Tumor necrosis factor-alpha mediates hyperglycemia-augmented gut barrier dysfunction in endotoxemia. Crit Care Med 2009 1.57
15 Role of soluble receptor for advanced glycation end products on endotoxin-induced lung injury. Am J Respir Crit Care Med 2008 1.47
16 Sputum cathelicidin, urokinase plasminogen activation system components, and cytokines discriminate cystic fibrosis, COPD, and asthma inflammation. Chest 2005 1.44
17 Plasma receptor for advanced glycation end-products predicts duration of ICU stay and mechanical ventilation in patients after lung transplantation. J Heart Lung Transplant 2007 1.44
18 Contribution of high-mobility group box-1 to the development of ventilator-induced lung injury. Am J Respir Crit Care Med 2006 1.42
19 Role of interleukin-6 in bleomycin-induced lung inflammatory changes in mice. Am J Respir Cell Mol Biol 2007 1.41
20 Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling. Cardiovasc Res 2008 1.35
21 Attenuation of endotoxin-induced acute lung injury by the Rho-associated kinase inhibitor, Y-27632. Am J Respir Cell Mol Biol 2005 1.35
22 Reversal of elastase-induced pulmonary emphysema and promotion of alveolar epithelial cell proliferation by simvastatin in mice. Am J Physiol Lung Cell Mol Physiol 2008 1.32
23 Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis. World J Surg 2006 1.30
24 Roles of oxidants and redox signaling in the pathogenesis of acute respiratory distress syndrome. Antioxid Redox Signal 2008 1.28
25 Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells. Cancer Cell Int 2008 1.26
26 Relationship between neutrophil elastase and acute lung injury in humans. Pulm Pharmacol Ther 2004 1.23
27 Enhancement of the endotoxin recognition pathway by ventilation with a large tidal volume in rabbits. Am J Physiol Lung Cell Mol Physiol 2003 1.13
28 Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther 2004 1.12
29 Systemic and local high mobility group box 1 concentrations during severe infection. Crit Care Med 2007 1.10
30 Pulmonary levels of high-mobility group box 1 during mechanical ventilation and ventilator-associated pneumonia. Shock 2008 1.09
31 Effect of CD14 blockade on endotoxin-induced acute lung injury in mice. Am J Respir Cell Mol Biol 2003 1.07
32 Radiation injury after hypofractionated stereotactic radiotherapy for peripheral small lung tumors: serial changes on CT. AJR Am J Roentgenol 2004 1.07
33 Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis. Respir Res 2009 1.02
34 Pharmacology of acute lung injury. Pulm Pharmacol Ther 2002 1.00
35 Hyperventilation and finger exercise increase venous-arterial Pco2 and pH differences. Am J Emerg Med 2008 0.98
36 Neutrophil elastase and systemic inflammatory response syndrome in the initiation and development of acute lung injury among critically ill patients. Biomed Pharmacother 2007 0.98
37 Elevated CC chemokine level in bronchoalveolar lavage fluid is predictive of a poor outcome of idiopathic pulmonary fibrosis. Respiration 2009 0.97
38 Production and activation of matrix metalloproteinase 7 (matrilysin 1) in the lungs of patients with idiopathic pulmonary fibrosis. Arch Pathol Lab Med 2010 0.96
39 TLR3-mediated synthesis and release of eotaxin-1/CCL11 from human bronchial smooth muscle cells stimulated with double-stranded RNA. J Immunol 2007 0.96
40 Various adhesion molecules impair microvascular leukocyte kinetics in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol 2005 0.96
41 Effects of pulmonary exposure to carbon nanotubes on lung and systemic inflammation with coagulatory disturbance induced by lipopolysaccharide in mice. Exp Biol Med (Maywood) 2008 0.95
42 Therapeutic effects of various initial combinations of chemotherapy including clarithromycin against Mycobacterium avium complex pulmonary disease. Chest 2009 0.94
43 Role of prostaglandin D(2) and its receptors in the pathophysiology of asthma. Allergol Int 2008 0.93
44 Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation. J Immunol 2008 0.93
45 Differences in pulmonary function before vs. 1 year after hypofractionated stereotactic radiotherapy for small peripheral lung tumors. Int J Radiat Oncol Biol Phys 2005 0.92
46 Neutrophil depletion attenuates interleukin-8 production in mild-overstretch ventilated normal rabbit lung. Crit Care Med 2004 0.92
47 Role of metallothionein in lung inflammation induced by ozone exposure in mice. Free Radic Biol Med 2008 0.92
48 Carbon black nanoparticles enhance bleomycin-induced lung inflammatory and fibrotic changes in mice. Exp Biol Med (Maywood) 2011 0.91
49 Acute lung inflammation and ventilator-induced lung injury caused by ATP via the P2Y receptors: an experimental study. Respir Res 2008 0.91
50 Role of Rho-kinase in reexpansion pulmonary edema in rabbits. Am J Physiol Lung Cell Mol Physiol 2005 0.90
51 Serodiagnostic contributions of antibody titers against mycobacterial lipid antigens in Mycobacterium avium complex pulmonary disease. Clin Infect Dis 2009 0.90
52 Gradual increase of high mobility group protein b1 in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis. Pulm Med 2011 0.88
53 Elevated serum adiponectin level in patients with Mycobacterium avium-intracellulare complex pulmonary disease. Respiration 2009 0.88
54 Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response. Respir Res 2009 0.87
55 Neutrophil elastase inhibitor improves survival of rats with clinically relevant sepsis. Shock 2010 0.87
56 Time to change diagnostic criteria of ARDS: towards the disease entity-based subgrouping. Pulm Pharmacol Ther 2005 0.86
57 Endothelin-1 level in epithelial lining fluid of patients with acute respiratory distress syndrome. Respirology 2007 0.85
58 Neutrophil elastase activity in acute lung injury and respiratory distress syndrome. Respirology 2008 0.85
59 Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cells. J Immunol 2011 0.85
60 High-mobility group box 1 contributes to lethality of endotoxemia in heme oxygenase-1-deficient mice. Am J Respir Cell Mol Biol 2008 0.85
61 Protective role of vascular endothelial growth factor in endotoxin-induced acute lung injury in mice. Respir Res 2007 0.85
62 Laminin gamma2 fragments are increased in the circulation of patients with early phase acute lung injury. Intensive Care Med 2009 0.85
63 [Chronic obstructive pulmonary disease (COPD) burden in Japan--confronting COPD Japan survey]. Nihon Kokyuki Gakkai Zasshi 2007 0.84
64 Effects of TNF-alpha-converting enzyme inhibition on acute lung injury induced by endotoxin in the rat. Shock 2009 0.84
65 Vascular endothelial growth factor in epithelial lining fluid of patients with acute respiratory distress syndrome. Respirology 2008 0.84
66 The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-Met inhibition. Mol Cancer Res 2010 0.84
67 Role of interleukin-6 in elastase-induced lung inflammatory changes in mice. Exp Lung Res 2010 0.83
68 Hyperoxia-induced emphysematous changes in subacute phase of endotoxin-induced lung injury in rats. Am J Physiol Lung Cell Mol Physiol 2004 0.83
69 Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin. Am J Physiol Lung Cell Mol Physiol 2008 0.83
70 An alternative method for screening EGFR mutation using RFLP in non-small cell lung cancer patients. J Thorac Oncol 2008 0.83
71 Early pulmonary resection for Mycobacterium avium complex lung disease treated with macrolides and quinolones. Ann Thorac Surg 2006 0.82
72 Concentrations of clarithromycin and active metabolite in the epithelial lining fluid of patients with Mycobacterium avium complex pulmonary disease. Pulm Pharmacol Ther 2008 0.82
73 Strain-specific phenotypes of airway inflammation and bronchial hyperresponsiveness induced by epicutaneous allergen sensitization in BALB/c and C57BL/6 mice. Int Arch Allergy Immunol 2010 0.82
74 Converging stereotactic radiotherapy using kilovoltage X-rays: experimental irradiation of normal rabbit lung and dose-volume analysis with Monte Carlo simulation. Int J Radiat Oncol Biol Phys 2009 0.81
75 Attenuation by intravenous 2-chloroadenosine of acute lung injury induced by live escherichia coli or latex particles added to endotoxin in the neutropenic state. J Lab Clin Med 2003 0.81
76 Exacerbation of bleomycin-induced injury and fibrosis by pneumonectomy in the residual lung of mice. J Surg Res 2008 0.81
77 Importance of tumor necrosis factor-alpha cleavage process in post-transplantation lung injury in rats. Am J Respir Crit Care Med 2004 0.81
78 Critical care in AJRCCM 2004. Am J Respir Crit Care Med 2005 0.80
79 Inhibition of neutrophil elastase reduces lung injury and bacterial count in hamsters. Pulm Pharmacol Ther 2008 0.80
80 PAF responsiveness in Japanese subjects with plasma PAF acetylhydrolase deficiency. Biochem Biophys Res Commun 2004 0.80
81 Fas ligand released by activated monocytes causes apoptosis of lung epithelial cells in human acute lung injury model in vitro. Biol Pharm Bull 2008 0.80
82 Association between beta-adrenoceptor gene polymorphisms and relative response to beta 2-agonists and anticholinergic drugs in Japanese asthmatic patients. Respirology 2010 0.80
83 Pharmacokinetics of telithromycin using bronchoscopic microsampling after single and multiple oral doses. Pulm Pharmacol Ther 2006 0.80
84 Bronchoscopic microsampling to analyze the epithelial lining fluid of patients with pulmonary Mycobacterium avium complex disease. Respiration 2008 0.80
85 Tacrolimus (FK506) has protective actions against murine bleomycin-induced acute lung injuries. Eur J Pharmacol 2005 0.80
86 Contributions of bronchoscopic microsampling in the supplemental diagnosis of small peripheral lung carcinoma. Ann Thorac Surg 2003 0.80
87 Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse. Respir Physiol Neurobiol 2005 0.80
88 [Small cell lung cancer with Sjögren's syndrome and Lambert-Eaton myasthenic syndrome]. Nihon Kokyuki Gakkai Zasshi 2006 0.80
89 Prediction of requirement for mechanical ventilation in community-acquired pneumonia with acute respiratory failure: a multicenter prospective study. Respiration 2012 0.79
90 Bronchoscopic microsampling is a useful complementary diagnostic tool for detecting lung cancer. Lung Cancer 2011 0.79
91 Pharmacokinetics of clarithromycin in bronchial epithelial lining fluid. Respirology 2008 0.79
92 Experimental stereotactic irradiation of normal rabbit lung: computed tomographic analysis of radiation injury and the histopathological features. Radiat Med 2007 0.79
93 Effect of Toll-like receptor 4 inhibitor on LPS-induced lung injury. Inflamm Res 2010 0.79
94 [Pulmonary fibrosis caused by ARDS]. Nihon Naika Gakkai Zasshi 2005 0.79
95 Inhibition of neutrophil elastase attenuates gut mucosal injury evoked by acute alveolar hypoxia in rabbits. Shock 2007 0.79
96 Impact of serum high-mobility group box 1 protein elevation on oxygenation impairment after thoracic aortic aneurysm repair. Heart Vessels 2010 0.78
97 Proteomic analysis of undiluted lung epithelial lining fluid. Chest 2008 0.78
98 Effects of long-term low-dose oxygen supplementation on the epithelial function, collagen metabolism and interstitial fibrogenesis in the guinea pig lung. Respir Res 2008 0.78
99 Effects of diesel exhaust particles on human neutrophil activation. Exp Lung Res 2006 0.78
100 Distinct epigenetic regulation of tumor suppressor genes in putative cancer stem cells of solid tumors. Int J Oncol 2010 0.78
101 Comparison of the pharmacodynamics of biapenem in bronchial epithelial lining fluid in healthy volunteers given half-hour and three-hour intravenous infusions. Antimicrob Agents Chemother 2009 0.78
102 Pharmacokinetics of gatifloxacin after a single oral dose in healthy young adult subjects and adult patients with chronic bronchitis, with a comparison of drug concentrations obtained by bronchoscopic microsampling and bronchoalveolar lavage. Clin Ther 2007 0.78
103 Gene expression analysis of endobronchial epithelial lining fluid in the evaluation of indeterminate pulmonary nodules. J Thorac Cardiovasc Surg 2009 0.78
104 Common functional polymorphisms in the cathepsin S promoter in Japanese subjects: possible contribution to pulmonary emphysema. Respirology 2008 0.78
105 In vivo IL-18 supplementation ameliorates lethal acute lung injury in burn-primed endotoxemic mice: a novel anti-inflammatory role of IL-18. Shock 2009 0.77
106 Human bronchial smooth muscle cell proliferation via thromboxane A2 receptor. Prostaglandins Leukot Essent Fatty Acids 2004 0.77
107 Epidural analgesia prevents endotoxin-induced gut mucosal injury in rabbits. Anesth Analg 2005 0.77
108 Activation of a neutrophil-derived inflammatory response in the airways during cardiopulmonary bypass. Anesth Analg 2006 0.77
109 High-mobility-group box chromosomal protein 1 as a new target for modulating stress response. Surg Today 2010 0.77
110 Involvement of E-cadherin cleavage in reperfusion injury. Eur J Cardiothorac Surg 2009 0.77
111 TP receptor-mediated release of eosinophil chemotactic activity from human bronchial smooth muscle cells. Eur J Pharmacol 2008 0.77
112 [Effect of direct hemoperfusion with a polymyxin B immobilized fiber column in acute exacerbation of interstitial pneumonia and serum indicators]. Nihon Kokyuki Gakkai Zasshi 2009 0.77
113 [Long-term treatment with a humanized anti-interleukin-6 receptor antibody (tocilizumab), improving interstitial pneumonia in a patient with multicentric Castleman disease]. Nihon Kokyuki Gakkai Zasshi 2010 0.76
114 New rapid detection test with a combination of polymerase chain reaction and immunochromatographic assay for Mycobacterium tuberculosis complex. Diagn Microbiol Infect Dis 2006 0.76
115 Age-dependent involvement of ATP-sensitive potassium channel Kir6.2 in hypoxic ventilatory depression of mouse. Respir Physiol Neurobiol 2008 0.76
116 Impact of pharmacokinetics and pharmacogenetics on the efficacy of pranlukast in Japanese asthmatics. Respirology 2009 0.76
117 Potassium channels in the central control of breathing. Adv Exp Med Biol 2006 0.76
118 Role of toll-like receptor 4 in acute neutrophilic lung inflammation induced by intratracheal bacterial products in mice. J Inflamm Res 2008 0.75
119 [Clinical features of Pneumocystis pneumonia in patients with systemic lupus erythematosus]. Nihon Kokyuki Gakkai Zasshi 2006 0.75
120 A case of Takayasu arteritis complicated by Castleman's disease. Clin Rheumatol 2008 0.75
121 [Progress in the treatment of ARDS]. Nihon Naika Gakkai Zasshi 2008 0.75
122 Update in critical care 2005. Am J Respir Crit Care Med 2006 0.75
123 [Appropriate hemodialysis scheduling based on therapeutic drug monitoring of carboplatin in a patient with lung cancer and chronic renal failure]. Gan To Kagaku Ryoho 2009 0.75
124 Update in critical care 2006. Am J Respir Crit Care Med 2007 0.75
125 Paravertebral extramedulary hematopoiesis arising with osteopetrosis tarda. Intern Med 2007 0.75
126 [Home oxygen therapy]. Nihon Rinsho 2007 0.75
127 [A case of miliary tuberculosis showing acute respiratory distress syndrome in rheumatoid arthritis]. Nihon Kokyuki Gakkai Zasshi 2010 0.75
128 [A case of early-onset COPD with recurrent pneumothorax]. Nihon Kokyuki Gakkai Zasshi 2009 0.75
129 Acute respiratory distress syndrome after percutaneous cryotherapy for a pulmonary metastatic lesion. Intern Med 2010 0.75
130 [Progress in mechanical ventilation therapy for patients with acute respiratory distress syndrome]. Nihon Naika Gakkai Zasshi 2004 0.75
131 [Combination chemotherapy with carboplatin and docetaxel for elderly patients with non-small-cell lung cancer]. Nihon Kokyuki Gakkai Zasshi 2008 0.75
132 F-18 FDG PET imaging in a patient with granulocyte colony stimulating factor producing pulmonary pleomorphic carcinoma. Clin Nucl Med 2008 0.75