Published in BMC Proc on December 15, 2009
Gene- or region-based analysis of genome-wide association studies. Genet Epidemiol (2009) 1.03
A robust model-free approach for rare variants association studies incorporating gene-gene and gene-environmental interactions. PLoS One (2013) 0.96
Gene- or region-based association study via kernel principal component analysis. BMC Genet (2011) 0.89
SNP set association analysis for genome-wide association studies. PLoS One (2013) 0.85
A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Hum Genet (2006) 28.32
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet (2004) 13.71
A review of the MHC genetics of rheumatoid arthritis. Genes Immun (2004) 3.77
Backward genotype-trait association (BGTA)-based dissection of complex traits in case-control designs. Hum Hered (2006) 1.52
Discovering interactions among BRCA1 and other candidate genes associated with sporadic breast cancer. Proc Natl Acad Sci U S A (2008) 1.50
Anti-heat shock protein 70 kDa and 90 kDa antibodies in serum of patients with rheumatoid arthritis. Ann Rheum Dis (1999) 1.06
Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6. Arthritis Rheum (2006) 0.98
Melanoma inhibitory activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rheumatoid arthritis. Ann Rheum Dis (2008) 0.92
Probing genetic overlap among complex human phenotypes. Proc Natl Acad Sci U S A (2007) 3.79
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. Nat Genet (2011) 3.66
Alendronate versus calcitriol for the prevention of bone loss after cardiac transplantation. N Engl J Med (2004) 3.44
The clonality of Staphylococcus aureus nasal carriage. J Infect Dis (2005) 2.39
How many people do you know?: Efficiently estimating personal network size. J Am Stat Assoc (2010) 2.37
Recent developments in top-emitting organic light-emitting diodes. Adv Mater (2010) 1.72
Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network. Genome Res (2008) 1.71
Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis. Methods (2005) 1.69
Backward Haplotype Transmission Association (BHTA) algorithm - a fast multiple-marker screening method. Hum Hered (2002) 1.63
Spontaneous mammary intraepithelial lesions in dogs--a model of breast cancer. Cancer Epidemiol Biomarkers Prev (2007) 1.56
Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness. Cancer Res (2005) 1.55
Backward genotype-trait association (BGTA)-based dissection of complex traits in case-control designs. Hum Hered (2006) 1.52
The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans. PLoS Genet (2013) 1.52
Discovering interactions among BRCA1 and other candidate genes associated with sporadic breast cancer. Proc Natl Acad Sci U S A (2008) 1.50
Automated reconstruction of neuronal morphology based on local geometrical and global structural models. Neuroinformatics (2011) 1.50
In vitro evaluation of the sealing ability of MTA used for the repair of furcation perforations with and without the use of an internal matrix. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2008) 1.48
Regularized sensitivity encoding (SENSE) reconstruction using Bregman iterations. Magn Reson Med (2009) 1.46
Hepatitis B virus status and the risk of pancreatic cancer: a meta-analysis. Eur J Cancer Prev (2013) 1.43
Neuroprotective effect on retinal ganglion cells by transpupillary laser irradiation of the optic nerve head. Neurosci Lett (2010) 1.42
A demonstration and findings of a statistical approach through reanalysis of inflammatory bowel disease data. Proc Natl Acad Sci U S A (2004) 1.40
To flip or not to flip: lipid-protein charge interactions are a determinant of final membrane protein topology. J Cell Biol (2008) 1.39
Clinical application and evaluation of Sysmex XE-5000 analyser for detecting nucleated red blood cells in peripheral blood. Clin Lab (2014) 1.38
Inference of regulatory gene interactions from expression data using three-way mutual information. Ann N Y Acad Sci (2009) 1.37
Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma. Mol Cancer Ther (2010) 1.37
WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells. Mol Cancer Ther (2009) 1.34
Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53. Cancer Prev Res (Phila) (2008) 1.34
A molecular signature predictive of indolent prostate cancer. Sci Transl Med (2013) 1.32
The association of serotonin transporter genetic polymorphisms and irritable bowel syndrome and its influence on tegaserod treatment in Chinese patients. Dig Dis Sci (2007) 1.32
Interaction-based feature selection and classification for high-dimensional biological data. Bioinformatics (2012) 1.26
Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells. J Orthop Res (2007) 1.20
A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice. Mol Ther (2013) 1.19
Monoglucosyldiacylglycerol, a foreign lipid, can substitute for phosphatidylethanolamine in essential membrane-associated functions in Escherichia coli. J Biol Chem (2003) 1.18
A novel mycovirus that is related to the human pathogen hepatitis E virus and rubi-like viruses. J Virol (2008) 1.16
Mapping the knowledge structure of research on patient adherence: knowledge domain visualization based co-word analysis and social network analysis. PLoS One (2012) 1.16
Segregation in social networks based on acquaintanceship and trust. AJS (2011) 1.15
A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis. Arthritis Rheumatol (2014) 1.14
NuMA influences higher order chromatin organization in human mammary epithelium. Mol Biol Cell (2006) 1.14
Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth. Int J Cancer (2010) 1.12
Association screening for genes with multiple potentially rare variants: an inverse-probability weighted clustering approach. BMC Proc (2011) 1.10
Frzb, a secreted Wnt antagonist, decreases growth and invasiveness of fibrosarcoma cells associated with inhibition of Met signaling. Cancer Res (2008) 1.10
A small-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway. Mol Pharmacol (2009) 1.08
Lipid-protein interactions drive membrane protein topogenesis in accordance with the positive inside rule. J Biol Chem (2008) 1.07
Renalase deficiency in heart failure model of rats--a potential mechanism underlying circulating norepinephrine accumulation. PLoS One (2011) 1.07
Dominant negative LRP5 decreases tumorigenicity and metastasis of osteosarcoma in an animal model. Clin Orthop Relat Res (2008) 1.06
Cyr61 is involved in neutrophil infiltration in joints by inducing IL-8 production by fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Res Ther (2013) 1.06
On-chip temperature gradient interaction chromatography. J Chromatogr A (2005) 1.06
Identification of gene interactions associated with disease from gene expression data using synergy networks. BMC Syst Biol (2008) 1.04
Transcription activity hot spot, is it real or an artifact? BMC Proc (2007) 1.04
New hepatitis E virus genotype in camels, the Middle East. Emerg Infect Dis (2014) 1.03
Differences in metabolite profile between blood plasma and serum. Anal Biochem (2010) 1.03
Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells. Mol Oncol (2012) 1.02
Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis. Protein Expr Purif (2005) 1.02
Kava components down-regulate expression of AR and AR splice variants and reduce growth in patient-derived prostate cancer xenografts in mice. PLoS One (2012) 1.01
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells. Mol Cancer Res (2012) 1.00
The challenge of detecting epistasis (G x G interactions): Genetic Analysis Workshop 16. Genet Epidemiol (2009) 0.99
Constructing gene association networks for rheumatoid arthritis using the backward genotype-trait association (BGTA) algorithm. BMC Proc (2007) 0.99
Identifying influential regions in extremely rare variants using a fixed-bin approach. BMC Proc (2011) 0.98
Effects of emodin and vitamin C on growth performance, biochemical parameters and two HSP70s mRNA expression of Wuchang bream (Megalobrama amblycephala Yih) under high temperature stress. Fish Shellfish Immunol (2012) 0.98
Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons. J Neurosci (2009) 0.97
AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4. J Biol Chem (2003) 0.97
Adenovirus-adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production. Hum Gene Ther (2009) 0.97
A novel miR-219-SMC4-JAK2/Stat3 regulatory pathway in human hepatocellular carcinoma. J Exp Clin Cancer Res (2014) 0.97
FSH beta gene mutations in a female with partial breast development and a male sibling with normal puberty and azoospermia. J Clin Endocrinol Metab (2002) 0.97
Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes. BMC Proc (2009) 0.96
Seasonal dynamics of phytoplankton and its relationship with the environmental factors in Dongping Lake, China. Environ Monit Assess (2012) 0.96
Molecular cloning and expression of two HSP70 genes in the Wuchang bream (Megalobrama amblycephala Yih). Fish Shellfish Immunol (2009) 0.95
Dynamic neural responses to cue-reactivity paradigms in heroin-dependent users: an fMRI study. Hum Brain Mapp (2009) 0.94
Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells. Proc Natl Acad Sci U S A (2012) 0.93
Pattern-based mining strategy to detect multi-locus association and gene x environment interaction. BMC Proc (2007) 0.93
A dominant-negative mutation of HSF2 associated with idiopathic azoospermia. Hum Genet (2012) 0.92
Characterization of the porcine alpha interferon multigene family. Gene (2006) 0.92
A Semi-Automated Positioning System for contact-mode Atomic Force Microscopy (AFM). IEEE Trans Autom Sci Eng (2013) 0.92
Clinical characteristics, diagnosis and management of respiratory distress syndrome in full-term neonates. Chin Med J (Engl) (2010) 0.91
Targeted blockade of interleukin-8 abrogates its promotion of cervical cancer growth and metastasis. Mol Cell Biochem (2012) 0.91
Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proc Natl Acad Sci U S A (2012) 0.91
Overexpression of the structural maintenance of chromosome 4 protein is associated with tumor de-differentiation, advanced stage and vascular invasion of primary liver cancer. Oncol Rep (2012) 0.90
Focus on vulnerable populations and promoting equity in health service utilization--an analysis of visitor characteristics and service utilization of the Chinese community health service. BMC Public Health (2014) 0.90
Lycopene enhances docetaxel's effect in castration-resistant prostate cancer associated with insulin-like growth factor I receptor levels. Neoplasia (2011) 0.90
Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC Evol Biol (2014) 0.90
Correlation of polymorphism of MTHFRs and RFC-1 genes with neural tube defects in China. Birth Defects Res A Clin Mol Teratol (2008) 0.89
Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP). Neurochem Int (2005) 0.89
Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis. Cancer Biol Ther (2009) 0.89
A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling. PLoS One (2014) 0.89
Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction. Hum Gene Ther (2013) 0.88
Proteomics-based approach to elucidate the mechanism of antitumor effect of curcumin in cervical cancer. Prostaglandins Leukot Essent Fatty Acids (2008) 0.88
Pretreatment with PTD-calbindin D 28k alleviates rat brain injury induced by ischemia and reperfusion. J Cereb Blood Flow Metab (2006) 0.87
Whole-genome synthesis and characterization of viable S13-like bacteriophages. PLoS One (2012) 0.87
Central amygdala GluA1 facilitates associative learning of opioid reward. J Neurosci (2013) 0.87