PubRank

Dong-Yup Lee

Author PubWeight™ 40.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation. Appl Environ Microbiol 2005 2.13
2 Systems biotechnology for strain improvement. Trends Biotechnol 2005 1.98
3 Metabolite essentiality elucidates robustness of Escherichia coli metabolism. Proc Natl Acad Sci U S A 2007 1.26
4 Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement. Microb Cell Fact 2010 1.23
5 WEbcoli: an interactive and asynchronous web application for in silico design and analysis of genome-scale E.coli model. Bioinformatics 2009 1.17
6 Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture. Biotechnol Bioeng 2012 1.17
7 BioSilico: an integrated metabolic database system. Bioinformatics 2004 1.12
8 Software applications for flux balance analysis. Brief Bioinform 2012 1.06
9 Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells. PLoS One 2011 0.99
10 Genome-scale modeling and in silico analysis of mouse cell metabolic network. Mol Biosyst 2009 0.95
11 Genome-scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis. Biotechnol Bioeng 2010 0.95
12 Flux-sum analysis: a metabolite-centric approach for understanding the metabolic network. BMC Syst Biol 2009 0.94
13 Exploring the effects of carbon sources on the metabolic capacity for shikimic acid production in Escherichia coli using in silico metabolic predictions. J Microbiol Biotechnol 2008 0.92
14 Centralized modularity of N-linked glycosylation pathways in mammalian cells. PLoS One 2009 0.92
15 Elucidating rice cell metabolism under flooding and drought stresses using flux-based modeling and analysis. Plant Physiol 2013 0.88
16 LC-MS-based metabolic characterization of high monoclonal antibody-producing Chinese hamster ovary cells. Biotechnol Bioeng 2012 0.87
17 Identification of cellular objective for elucidating the physiological state of plasmid-bearing Escherichia coli using genome-scale in silico analysis. Biotechnol Prog 2009 0.87
18 Multiobjective flux balancing using the NISE method for metabolic network analysis. Biotechnol Prog 2009 0.86
19 MetaFluxNet, a program package for metabolic pathway construction and analysis, and its use in large-scale metabolic flux analysis of Escherichia coli. Genome Inform 2003 0.86
20 Incorporating metabolic flux ratios into constraint-based flux analysis by using artificial metabolites and converging ratio determinants. J Biotechnol 2007 0.85
21 Integrated transcriptome and binding sites analysis implicates E2F in the regulation of self-renewal in human pluripotent stem cells. PLoS One 2011 0.85
22 Computational codon optimization of synthetic gene for protein expression. BMC Syst Biol 2012 0.85
23 Characterizing Escherichia coli DH5alpha growth and metabolism in a complex medium using genome-scale flux analysis. Biotechnol Bioeng 2009 0.84
24 Modeling and optimization of a multi-product biosynthesis factory for multiple objectives. Metab Eng 2010 0.84
25 Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: overexpression of malate dehydrogenase II. J Biotechnol 2010 0.83
26 Identifying essential genes/reactions of the rice photorespiration by in silico model-based analysis. Rice (N Y) 2013 0.82
27 Patterns of cis-element enrichment reveal potential regulatory modules involved in the transcriptional regulation of anoxia response of japonica rice. Gene 2012 0.82
28 Elucidation of metabolism in hybridoma cells grown in fed-batch culture by genome-scale modeling. Biotechnol Bioeng 2009 0.81
29 How necessary is a fast testkit for mitigation of pandemic flu? J R Soc Interface 2009 0.80
30 Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells. Biotechnol J 2014 0.79
31 Translatome analysis of CHO cells to identify key growth genes. J Biotechnol 2013 0.79
32 Enhanced production of neuroprogenitors, dopaminergic neurons, and identification of target genes by overexpression of sonic hedgehog in human embryonic stem cells. Stem Cells Dev 2011 0.79
33 Enhanced expression of codon optimized interferon gamma in CHO cells. J Biotechnol 2013 0.79
34 An alpha-numeric code for representing N-linked glycan structures in secreted glycoproteins. Bioprocess Biosyst Eng 2008 0.79
35 MFAML: a standard data structure for representing and exchanging metabolic flux models. Bioinformatics 2005 0.79
36 Combined data preprocessing and multivariate statistical analysis characterizes fed-batch culture of mouse hybridoma cells for rational medium design. J Biotechnol 2010 0.79
37 Mathematical modeling and sensitivity analysis of the integrated TNFα-mediated apoptotic pathway for identifying key regulators. Comput Biol Med 2011 0.78
38 In silico analyses for the discovery of tuberculosis drug targets. J Antimicrob Chemother 2013 0.78
39 Cofactor modification analysis: a computational framework to identify cofactor specificity engineering targets for strain improvement. J Bioinform Comput Biol 2013 0.78
40 NADPH-dependent pgi-gene knockout Escherichia coli metabolism producing shikimate on different carbon sources. FEMS Microbiol Lett 2011 0.78
41 Metabolomics-based identification of apoptosis-inducing metabolites in recombinant fed-batch CHO culture media. J Biotechnol 2010 0.77
42 Metabolic reconstruction and flux analysis of industrial Pichia yeasts. Appl Microbiol Biotechnol 2013 0.77
43 Strain improvement and process development for biobutanol production. Recent Pat Biotechnol 2009 0.76
44 Integrative analysis workflow for the structural and functional classification of C-type lectins. BMC Bioinformatics 2011 0.75