Published in J Biol Chem on December 22, 2009
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NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila. Genes Dev (2003) 3.65
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Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element. Mol Cell Biol (2004) 2.49
Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene. Mol Cell Biol (2006) 2.40
Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor. Genes Dev (2004) 2.35
NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs. Mol Cell (2007) 2.24
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Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II. Proc Natl Acad Sci U S A (2004) 2.01
Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling. Proc Natl Acad Sci U S A (2009) 1.83
Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes. Mol Cell Biol (2008) 1.60
Negative elongation factor NELF represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex. J Biol Chem (2007) 1.51
Regulation of clustered gene expression by cofactor of BRCA1 (COBRA1) in breast cancer cells. Oncogene (2006) 0.96
Cofactor of BRCA1 modulates androgen-dependent transcription and alternative splicing. J Steroid Biochem Mol Biol (2007) 0.95
Deregulation of cofactor of BRCA1 expression in breast cancer cells. J Cell Biochem (2008) 0.94
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Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor. Cell (2008) 3.26
Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. Circulation (2008) 2.98
The structural basis of actin filament branching by the Arp2/3 complex. J Cell Biol (2008) 2.82
The RickA protein of Rickettsia conorii activates the Arp2/3 complex. Nature (2004) 2.73
Motility and segregation of Hsp104-associated protein aggregates in budding yeast. Cell (2011) 2.72
Bacterial peptidoglycan triggers Candida albicans hyphal growth by directly activating the adenylyl cyclase Cyr1p. Cell Host Microbe (2008) 2.68
Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity. Cell (2007) 2.61
Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling. J Cell Biol (2004) 2.56
Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis. Curr Biol (2002) 2.38
Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor. Genes Dev (2004) 2.35
The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration. J Cell Biol (2012) 2.34
The Ran GTPase mediates chromatin signaling to control cortical polarity during polar body extrusion in mouse oocytes. Dev Cell (2007) 2.27
ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. J Clin Invest (2008) 2.16
Mapping dynamic protein interactions in MAP kinase signaling using live-cell fluorescence fluctuation spectroscopy and imaging. Proc Natl Acad Sci U S A (2007) 2.06
Mitochondrial translocation of cofilin is an early step in apoptosis induction. Nat Cell Biol (2003) 1.94
MicroRNA-204/211 alters epithelial physiology. FASEB J (2010) 1.83
Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy. Nature (2012) 1.82
Unusual variants of Alexander's disease. Ann Neurol (2005) 1.76
Dual modes of cdc42 recycling fine-tune polarized morphogenesis. Dev Cell (2009) 1.73
Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes. Nat Cell Biol (2011) 1.73
Monitoring the safety of quadrivalent human papillomavirus vaccine: findings from the Vaccine Safety Datalink. Vaccine (2011) 1.70
Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited. Mol Biol Cell (2011) 1.68
Local injury to the endometrium in controlled ovarian hyperstimulation cycles improves implantation rates. Fertil Steril (2007) 1.65
Actin-driven chromosomal motility leads to symmetry breaking in mammalian meiotic oocytes. Nat Cell Biol (2008) 1.65
microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells. Biochem Biophys Res Commun (2010) 1.63
Symmetry breaking in the life cycle of the budding yeast. Cold Spring Harb Perspect Biol (2009) 1.62
Cortactin regulates cell migration through activation of N-WASP. J Cell Sci (2004) 1.61
Spontaneous cell polarization: undermining determinism. Nat Cell Biol (2003) 1.59
Control of chemokine gradients by the retinal pigment epithelium. Invest Ophthalmol Vis Sci (2008) 1.55
ARPC1/Arc40 mediates the interaction of the actin-related protein 2 and 3 complex with Wiskott-Aldrich syndrome protein family activators. J Biol Chem (2004) 1.53
Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions. PLoS Biol (2005) 1.52
Cell cycle-regulated trafficking of Chs2 controls actomyosin ring stability during cytokinesis. Mol Biol Cell (2005) 1.49
Dynamics of yeast Myosin I: evidence for a possible role in scission of endocytic vesicles. Curr Biol (2004) 1.47
Actin depolymerization drives actomyosin ring contraction during budding yeast cytokinesis. Dev Cell (2012) 1.41
Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet (2003) 1.40
Serum protein profiles in myasthenia gravis. Ann Thorac Surg (2009) 1.39
General regulatory factors (GRFs) as genome partitioners. J Biol Chem (2002) 1.39
Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet. Circ Res (2009) 1.39
Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer. Curr Opin Cell Biol (2010) 1.38
A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease. Nat Med (2008) 1.38
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome Biol (2014) 1.36
Karyotypic determinants of chromosome instability in aneuploid budding yeast. PLoS Genet (2012) 1.36
mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review). Int J Oncol (2007) 1.34
Comparison of ABF1 and RAP1 in chromatin opening and transactivator potentiation in the budding yeast Saccharomyces cerevisiae. Mol Cell Biol (2004) 1.33
Real-time surveillance to assess risk of intussusception and other adverse events after pentavalent, bovine-derived rotavirus vaccine. Pediatr Infect Dis J (2010) 1.32
Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell (2003) 1.32
The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes. J Clin Endocrinol Metab (2008) 1.32
miR-186 downregulation correlates with poor survival in lung adenocarcinoma, where it interferes with cell-cycle regulation. Cancer Res (2012) 1.29
Three-dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors. EMBO J (2011) 1.29
miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. Cancer Res (2013) 1.27
Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancer. J Biol Chem (2011) 1.26
Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae. Mol Cell Biol (2002) 1.25
Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression. Oncogene (2005) 1.25
Ancient orphan crop joins modern era: gene-based SNP discovery and mapping in lentil. BMC Genomics (2013) 1.24
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CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients. BMC Med (2012) 1.23
Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rat. Nephrol Dial Transplant (2007) 1.20
A missense mutation in the gammaD-crystallin gene CRYGD associated with autosomal dominant congenital cataract in a Chinese family. Mol Vis (2006) 1.19
Complete genome sequence of Bacillus subtilis BSn5, an endophytic bacterium of Amorphophallus konjac with antimicrobial activity for the plant pathogen Erwinia carotovora subsp. carotovora. J Bacteriol (2011) 1.19
Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol (2002) 1.18
Actin cytoskeleton in cell polarity and asymmetric division during mouse oocyte maturation. Cytoskeleton (Hoboken) (2012) 1.18
Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation. Arterioscler Thromb Vasc Biol (2011) 1.16
NMR analyses of the activation of the Arp2/3 complex by neuronal Wiskott-Aldrich syndrome protein. Biochemistry (2005) 1.16
Actin polymerization: riding the wave. Curr Biol (2004) 1.15
Role of endometrial blood flow assessment with color Doppler energy in predicting pregnancy outcome of IVF-ET cycles. Reprod Biol Endocrinol (2010) 1.14
The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27. Am J Hum Genet (2006) 1.13
Flippase-mediated phospholipid asymmetry promotes fast Cdc42 recycling in dynamic maintenance of cell polarity. Nat Cell Biol (2012) 1.12
Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth. Cancer Res (2012) 1.12
Genome-wide analysis of ARS (autonomously replicating sequence) binding factor 1 (Abf1p)-mediated transcriptional regulation in Saccharomyces cerevisiae. J Biol Chem (2004) 1.12
TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca(2+) influx. Cell Calcium (2010) 1.11
Tumor suppressor BRCA1 inhibits a breast cancer-associated promoter of the aromatase gene (CYP19) in human adipose stromal cells. Am J Physiol Endocrinol Metab (2006) 1.11
Cattle mammary bioreactor generated by a novel procedure of transgenic cloning for large-scale production of functional human lactoferrin. PLoS One (2008) 1.11
Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts. Development (2010) 1.10
Better survival with EGFR exon 19 than exon 21 mutations in gefitinib-treated non-small cell lung cancer patients is due to differential inhibition of downstream signals. Cancer Lett (2008) 1.10
Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs. Mol Ther (2012) 1.10
Ethnobotanical studies on medicinal plants used by the red-headed yao people in Jinping, Yunnan Province, China. J Ethnopharmacol (2004) 1.09
Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer. Cancer Cell (2013) 1.09
SAM domain-based protein oligomerization observed by live-cell fluorescence fluctuation spectroscopy. PLoS One (2008) 1.08
Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury. Am J Physiol Endocrinol Metab (2009) 1.08
Characterization of bioactive recombinant human lysozyme expressed in milk of cloned transgenic cattle. PLoS One (2011) 1.07
Herbs for medicinal baths among the traditional Yao communities of China. J Ethnopharmacol (2006) 1.07
Rapid de-localization of actin leading edge components with BDM treatment. BMC Cell Biol (2003) 1.07
Efficacy and safety of tigecycline monotherapy vs. imipenem/cilastatin in Chinese patients with complicated intra-abdominal infections: a randomized controlled trial. BMC Infect Dis (2010) 1.06
JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction. Genes Dev (2002) 1.06
Mitotic-exit control as an evolved complex system. Cell (2005) 1.06
LIM kinase 2 is widely expressed in all tissues. J Histochem Cytochem (2006) 1.05
Identification of a multifunctional domain in autonomously replicating sequence-binding factor 1 required for transcriptional activation, DNA replication, and gene silencing. Mol Cell Biol (2002) 1.05
Near real-time surveillance for influenza vaccine safety: proof-of-concept in the Vaccine Safety Datalink Project. Am J Epidemiol (2009) 1.04
Activation of Arp2/3 complex-dependent actin polymerization by plant proteins distantly related to Scar/WAVE. Proc Natl Acad Sci U S A (2004) 1.04
Characteristics of abnormal menstrual cycle and polycystic ovary syndrome in community and hospital populations. Chin Med J (Engl) (2010) 1.04
FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation. Cell Res (2013) 1.03
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TGF-β-induced miR-21 negatively regulates the antiproliferative activity but has no effect on EMT of TGF-β in HaCaT cells. Int J Biochem Cell Biol (2011) 1.03
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The protein SET binds the neuronal Cdk5 activator p35nck5a and modulates Cdk5/p35nck5a activity. J Biol Chem (2001) 1.02