Published in Mol Biol Cell on December 23, 2009
The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nat Cell Biol (2011) 3.17
Cep152 interacts with Plk4 and is required for centriole duplication. J Cell Biol (2010) 2.45
3D-structured illumination microscopy provides novel insight into architecture of human centrosomes. Biol Open (2012) 2.23
Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation. Curr Biol (2014) 1.76
The conversion of centrioles to centrosomes: essential coupling of duplication with segregation. J Cell Biol (2011) 1.68
The centrosome is an actin-organizing centre. Nat Cell Biol (2015) 1.54
Causes and consequences of centrosome abnormalities in cancer. Philos Trans R Soc Lond B Biol Sci (2014) 1.26
The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. Genes Dev (2012) 1.23
The centrosome and its duplication cycle. Cold Spring Harb Perspect Biol (2015) 1.23
Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole. Nat Commun (2014) 1.18
The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification. J Cell Biol (2011) 1.16
Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors. Dev Cell (2011) 1.16
Deuterosome-mediated centriole biogenesis. Dev Cell (2013) 1.12
Polo-like kinase 4: the odd one out of the family. Cell Div (2010) 1.03
Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis. Nat Struct Mol Biol (2014) 0.98
Primary ciliogenesis requires the distal appendage component Cep123. Biol Open (2013) 0.97
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer. Front Oncol (2013) 0.96
Polo-like kinase 4 autodestructs by generating its Slimb-binding phosphodegron. Curr Biol (2013) 0.95
SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress. Nat Commun (2013) 0.92
Centriole duplication: A lesson in self-control. Cell Cycle (2010) 0.92
Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs. PLoS One (2013) 0.91
Spindle formation in the mouse embryo requires Plk4 in the absence of centrioles. Dev Cell (2013) 0.90
CDK11(p58) is required for centriole duplication and Plk4 recruitment to mitotic centrosomes. PLoS One (2011) 0.88
SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosis. PLoS One (2012) 0.87
The life cycle of centrioles. Cold Spring Harb Symp Quant Biol (2011) 0.85
The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels. J Cell Sci (2012) 0.84
Male hypogonadism and germ cell loss caused by a mutation in Polo-like kinase 4. Endocrinology (2011) 0.82
Plk4/SAK/ZYG-1 in the regulation of centriole duplication. F1000 Biol Rep (2010) 0.82
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification. Nat Commun (2016) 0.81
PIPKIγ targets to the centrosome and restrains centriole duplication. J Cell Sci (2014) 0.81
CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis. Curr Biol (2016) 0.79
NFκB regulates expression of Polo-like kinase 4. Cell Cycle (2013) 0.79
A novel role for Plk4 in regulating cell spreading and motility. Oncogene (2014) 0.79
A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4. Nat Commun (2016) 0.75
Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication. PLoS Genet (2017) 0.75
Expression of Polo-Like Kinase 4(PLK4) in Breast Cancer and Its Response to Taxane-Based Neoadjuvant Chemotherapy. J Cancer (2016) 0.75
Everything in moderation: Proteolytic regulation of centrosome duplication. Worm (2013) 0.75
Analysis of centrosome and DNA damage response in PLK4 associated Seckel syndrome. Eur J Hum Genet (2017) 0.75
The Polo kinase Plk4 functions in centriole duplication. Nat Cell Biol (2005) 5.84
Plk4-induced centriole biogenesis in human cells. Dev Cell (2007) 5.68
The centriole cycle in synchronized HeLa cells. J Cell Biol (1968) 5.05
The respective contributions of the mother and daughter centrioles to centrosome activity and behavior in vertebrate cells. J Cell Biol (2000) 4.97
SAK/PLK4 is required for centriole duplication and flagella development. Curr Biol (2005) 4.52
Centrosome composition and microtubule anchoring mechanisms. Curr Opin Cell Biol (2002) 4.11
Centrioles in the cell cycle. I. Epithelial cells. J Cell Biol (1982) 3.78
Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat Cell Biol (1999) 3.74
SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells. Nat Cell Biol (2005) 3.37
Most of centrin in animal cells is not centrosome-associated and centrosomal centrin is confined to the distal lumen of centrioles. J Cell Sci (1996) 3.27
Centriole cycle in Chinese hamster ovary cells as determined by whole-mount electron microscopy. J Cell Biol (1981) 3.17
Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity. Proc Natl Acad Sci U S A (2006) 3.15
Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: the role of ninein. J Cell Sci (2000) 3.07
The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo. Cell (2001) 2.92
Centrosome control of the cell cycle. Trends Cell Biol (2005) 2.83
Centrosome organization and centriole architecture: their sensitivity to divalent cations. J Struct Biol (1993) 2.83
CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. Dev Cell (2002) 2.74
Revisiting the role of the mother centriole in centriole biogenesis. Science (2007) 2.59
SAS-4 is essential for centrosome duplication in C elegans and is recruited to daughter centrioles once per cell cycle. Dev Cell (2003) 2.50
The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication. J Cell Biol (2009) 2.43
The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4. Curr Biol (2008) 2.33
Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis. Nat Genet (2005) 1.97
The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization. Nat Struct Biol (2002) 1.76
Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression. Proc Natl Acad Sci U S A (2003) 1.69
Independence of centriole formation and DNA synthesis. J Cell Biol (1973) 1.68
Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. Mol Biol Cell (2008) 1.58
Late mitotic failure in mice lacking Sak, a polo-like kinase. Curr Biol (2001) 1.53
Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates. Oncogene (2007) 1.52
hPOC5 is a centrin-binding protein required for assembly of full-length centrioles. J Cell Biol (2009) 1.49
Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation. Proc Natl Acad Sci U S A (1994) 1.43
Comparative study and improvement of current cell micro-patterning techniques. Lab Chip (2007) 1.37
Simple and rapid process for single cell micro-patterning. Lab Chip (2009) 1.35
Polo-like kinase-2 is required for centriole duplication in mammalian cells. Curr Biol (2004) 1.33
GFP-centrin as a marker for centriole dynamics in living cells. Microsc Res Tech (2000) 1.28
The conserved protein SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size. Dev Cell (2008) 1.27
Constitutive expression of murine Sak-a suppresses cell growth and induces multinucleation. Mol Cell Biol (1996) 1.26
Identification of an Spc110p-related protein in vertebrates. J Cell Sci (1997) 1.16
Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication. J Cell Biol (2008) 1.09
Mitotic regulators govern progress through steps in the centrosome duplication cycle. J Cell Biol (1999) 1.06
Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase. J Biol Chem (2001) 1.01
Determination of the Plk4/Sak consensus phosphorylation motif using peptide spots arrays. FEBS Lett (2006) 0.95
The extracellular matrix guides the orientation of the cell division axis. Nat Cell Biol (2005) 5.00
Protein interaction mapping: a Drosophila case study. Genome Res (2005) 4.15
Experimental and theoretical study of mitotic spindle orientation. Nature (2007) 3.48
Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity. Proc Natl Acad Sci U S A (2006) 3.15
External forces control mitotic spindle positioning. Nat Cell Biol (2011) 3.13
GMAP-210 recruits gamma-tubulin complexes to cis-Golgi membranes and is required for Golgi ribbon formation. Cell (2004) 2.85
The universal dynamics of cell spreading. Curr Biol (2007) 2.74
The power of species sorting: local factors drive bacterial community composition over a wide range of spatial scales. Proc Natl Acad Sci U S A (2007) 2.68
Cell distribution of stress fibres in response to the geometry of the adhesive environment. Cell Motil Cytoskeleton (2006) 2.63
Cell shape and cell division. Curr Opin Cell Biol (2006) 2.47
Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function. J Cell Sci (2005) 2.44
Decreased mechanical stiffness in LMNA-/- cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies. Hum Mol Genet (2004) 2.42
Structure and duplication of the centrosome. J Cell Sci (2007) 2.26
Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends. J Cell Biol (2006) 2.25
A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5-8. Int J Cancer (2003) 2.24
Nucleokinesis in tangentially migrating neurons comprises two alternating phases: forward migration of the Golgi/centrosome associated with centrosome splitting and myosin contraction at the rear. J Neurosci (2005) 2.20
Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130. EMBO J (2009) 2.00
Cortical actomyosin breakage triggers shape oscillations in cells and cell fragments. Biophys J (2005) 1.96
Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature. Blood (2006) 1.82
Partial cell fusion: a newly recognized type of communication between dedifferentiating cardiomyocytes and fibroblasts. Cardiovasc Res (2005) 1.67
The Rho-associated protein kinase p160ROCK is required for centrosome positioning. J Cell Biol (2002) 1.65
The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus. EMBO J (2006) 1.61
PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression. J Cell Sci (2003) 1.60
Relationship between bacterial community composition and bottom-up versus top-down variables in four eutrophic shallow lakes. Appl Environ Microbiol (2002) 1.60
The Golgi apparatus at the cell centre. Curr Opin Cell Biol (2003) 1.59
Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity. Mol Biol Cell (2003) 1.57
Physical mechanisms redirecting cell polarity and cell shape in fission yeast. Curr Biol (2008) 1.55
Cell shape and contractility regulate ciliogenesis in cell cycle-arrested cells. J Cell Biol (2010) 1.54
hPOC5 is a centrin-binding protein required for assembly of full-length centrioles. J Cell Biol (2009) 1.49
Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies. Hum Mol Genet (2011) 1.47
Microtubule release from the centrosome in migrating cells. J Cell Biol (2002) 1.44
Characterization of bacterial communities in four freshwater lakes differing in nutrient load and food web structure. FEMS Microbiol Ecol (2005) 1.43
Dynamic modes of the cortical actomyosin gel during cell locomotion and division. Trends Cell Biol (2005) 1.42
Keratin 8/18 breakdown and reorganization during apoptosis. Exp Cell Res (2004) 1.42
Transition of high-grade cervical intraepithelial neoplasia to micro-invasive carcinoma is characterized by integration of HPV 16/18 and numerical chromosome abnormalities. J Pathol (2004) 1.41
Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles. Cancer Biol Ther (2004) 1.40
Dissociating the centrosomal matrix protein AKAP450 from centrioles impairs centriole duplication and cell cycle progression. Mol Biol Cell (2003) 1.40
Comparative study and improvement of current cell micro-patterning techniques. Lab Chip (2007) 1.37
Simple and rapid process for single cell micro-patterning. Lab Chip (2009) 1.35
A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint. EMBO J (2006) 1.33
P21 Cip1/WAF1 expression is strongly associated with HPV-positive tonsillar carcinoma and a favorable prognosis. Mod Pathol (2009) 1.29
Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis. J Cell Biol (2011) 1.28
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. J Biol Chem (2006) 1.28
Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts. J Cell Biol (2007) 1.27
The centrosome-nucleus complex and microtubule organization in the Drosophila oocyte. Development (2005) 1.24
Molecular and cellular biology of neuroendocrine lung tumors: evidence for separate biological entities. Biochim Biophys Acta (2012) 1.24
Laminopathies. J Pathol (2004) 1.20
Get round and stiff for mitosis. HFSP J (2008) 1.19
Conformational analysis of r207910, a new drug candidate for the treatment of tuberculosis, by a combined NMR and molecular modeling approach. Chem Biol Drug Des (2006) 1.17
Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex. J Cell Sci (2007) 1.16
Probabilistic density maps to study global endomembrane organization. Nat Methods (2010) 1.15
Cell confinement controls centrosome positioning and lumen initiation during epithelial morphogenesis. J Cell Biol (2012) 1.13
Compound heterozygosity for mutations in LMNA causes a progeria syndrome without prelamin A accumulation. Hum Mol Genet (2006) 1.11
Assessing the localization of centrosomal proteins by PALM/STORM nanoscopy. Cytoskeleton (Hoboken) (2011) 1.11
Supratentorial grade II astrocytoma: biological features and clinical course. Lancet Neurol (2003) 1.10
Fission yeast cdc31p is a component of the half-bridge and controls SPB duplication. Mol Biol Cell (2003) 1.10
Centrioles resist forces applied on centrosomes during G2/M transition. Biol Cell (2005) 1.07
Dual roles of intermediate filaments in apoptosis. Exp Cell Res (2007) 1.06
Reverse structural and gap-junctional remodeling after prolonged atrial fibrillation in the goat. Circulation (2003) 1.04
Identification of proteomic differences between squamous cell carcinoma of the lung and bronchial epithelium. Mol Cell Proteomics (2009) 1.04
Dietary plant sterols accumulate in the brain. Biochim Biophys Acta (2006) 1.04
Polo-like kinase 4: the odd one out of the family. Cell Div (2010) 1.03
Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type lamins. Biochim Biophys Acta (2010) 1.02
Polymerase chain reaction denaturing gradient gel electrophoresis analysis of the N2-fixing bacterial diversity in soil under Acacia tortilis ssp. raddiana and Balanites aegyptiaca in the dryland part of Senegal. Environ Microbiol (2004) 1.01
Re-expression of alpha skeletal actin as a marker for dedifferentiation in cardiac pathologies. J Cell Mol Med (2009) 1.01
Next-generation treatment strategies for human papillomavirus-related head and neck squamous cell carcinoma: where do we go? Rev Med Virol (2011) 1.00
HPV in situ hybridization: impact of different protocols on the detection of integrated HPV. Int J Cancer (2005) 1.00
Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus. Neurobiol Dis (2004) 0.99
Centrin4p, a novel mammalian centrin specifically expressed in ciliated cells. Mol Biol Cell (2003) 0.98
Bax expression and growth behavior of basal cell carcinomas. J Cutan Pathol (2002) 0.97
The overexpression of GMAP-210 blocks anterograde and retrograde transport between the ER and the Golgi apparatus. Traffic (2002) 0.97
Primary ciliogenesis requires the distal appendage component Cep123. Biol Open (2013) 0.97
Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis. Eur J Cell Biol (2002) 0.96
Golgi localisation of GMAP210 requires two distinct cis-membrane binding mechanisms. BMC Biol (2009) 0.96
Discrimination of DNA and RNA in cells by a vital fluorescent probe: lifetime imaging of SYTO13 in healthy and apoptotic cells. Cytometry (2002) 0.96
Gain of chromosome 7, as detected by in situ hybridization, strongly correlates with shorter survival in astrocytoma grade 2. Genes Chromosomes Cancer (2002) 0.95
GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail. Dev Dyn (2011) 0.94
Distribution pattern and marker profile show two subpopulations of reserve cells in the endocervical canal. Int J Gynecol Pathol (2009) 0.93
Translation of a tumor microenvironment mimicking 3D tumor growth co-culture assay platform to high-content screening. J Biomol Screen (2012) 0.91
Serum markers in small cell lung cancer: opportunities for improvement. Biochim Biophys Acta (2013) 0.90
Deletions of 11q22.3-q25 are associated with atypical lung carcinoids and poor clinical outcome. Am J Pathol (2011) 0.89
Reorganization of the nuclear lamina and cytoskeleton in adipogenesis. Histochem Cell Biol (2011) 0.89
Phylogenetic analysis of partial bacterial 16S rDNA sequences of tropical grass pasture soil under Acacia tortilis subsp. raddiana in Senegal. Syst Appl Microbiol (2004) 0.89
Human apolipoprotein C-I expression in mice impairs learning and memory functions. J Lipid Res (2007) 0.89
Structural remodelling of cardiomyocytes in the border zone of infarcted rabbit heart. Mol Cell Biochem (2007) 0.89
Practices associated with Highly Pathogenic Avian Influenza spread in traditional poultry marketing chains: Social and economic perspectives. Acta Trop (2013) 0.88
Reserve cells in human uterine cervical epithelium are derived from müllerian epithelium at midgestational age. Int J Gynecol Pathol (2007) 0.88
Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines. Int J Cancer (2014) 0.88
Structural adaptation in adult rabbit ventricular myocytes: influence of dynamic physical interaction with fibroblasts. Cell Biochem Biophys (2006) 0.87
Effects of mistletoe (Viscum album L.) extracts Iscador on cell cycle and survival of tumor cells. Arzneimittelforschung (2006) 0.87
The R439C mutation in LMNA causes lamin oligomerization and susceptibility to oxidative stress. J Cell Mol Med (2009) 0.87
Increase in viral load, viral integration, and gain of telomerase genes during uterine cervical carcinogenesis can be simultaneously assessed by the HPV 16/18 MLPA-assay. Am J Pathol (2010) 0.86
P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias. Int J Cancer (2013) 0.86
Differential effects of Viscum album extract IscadorQu on cell cycle progression and apoptosis in cancer cells. Int J Oncol (2004) 0.86
A new multiparameter assay to assess HPV 16/18, viral load and physical status together with gain of telomerase genes in HPV-related cancers. Int J Cancer (2010) 0.85
Interobserver variability for the WHO classification of pulmonary carcinoids. Am J Surg Pathol (2014) 0.85
MEN1 gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids. J Clin Endocrinol Metab (2013) 0.85
Absence of ApoE upregulates murine brain ApoD and ABCA1 levels, but does not affect brain sterol levels, while human ApoE3 and human ApoE4 upregulate brain cholesterol precursor levels. J Alzheimers Dis (2009) 0.84