Published in Eur J Biochem on November 01, 1977
Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome--an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13. Am J Hum Genet (2008) 1.43
Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase. EMBO J (1997) 1.37
Partial Purification and Characterization of the Gibberellin A(20) 3beta-Hydroxylase from Seeds of Phaseolus vulgaris. Plant Physiol (1990) 1.29
The diverse and pervasive chemistries of the alpha-keto acid dependent enzymes. J Biol Inorg Chem (2007) 1.23
Role of Ngamma-acetyldiaminobutyrate as an enzyme stabilizer and an intermediate in the biosynthesis of hydroxyectoine. Appl Environ Microbiol (1999) 1.23
A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. J Cell Sci (2006) 1.20
Severe hypovitaminosis C in lung-cancer patients: the utilization of vitamin C in surgical repair and lymphocyte-related host resistance. Br J Cancer (1982) 1.19
Differences between collagen hydroxylases and 2-oxoglutarate dehydrogenase in their inhibition by structural analogues of 2-oxoglutarate. Biochem J (1985) 1.13
Isolation of lysyl hydroxylase, an enzyme of collagen synthesis, from chick embryos as a homogeneous protein. Biochem J (1980) 1.11
Time-dependent inactivation of chick-embryo prolyl 4-hydroxylase by coumalic acid. Evidence for a syncatalytic mechanism. Biochem J (1987) 1.01
Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection. Front Biosci (2008) 0.99
Characterization of a low-relative-molecular-mass prolyl 4-hydroxylase from the green alga Chlamydomonas reinhardii. Biochem J (1987) 0.98
Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia. Biochim Biophys Acta (2007) 0.97
Syncatalytic inactivation of prolyl 4-hydroxylase by anthracyclines. Biochem J (1988) 0.96
Purification and cloning of a proline 3-hydroxylase, a novel enzyme which hydroxylates free L-proline to cis-3-hydroxy-L-proline. J Bacteriol (1997) 0.95
The source of oxygen in the reaction catalysed by collagen lysyl hydroxylase. Biochem J (1983) 0.92
Inhibition of prolyl 4-hydroxylase by hydroxyanthraquinones. Biochem J (1986) 0.90
The catalytic mechanism of the hydroxylation reaction of peptidyl proline and lysine does not require protein disulphide-isomerase activity. Biochem J (1989) 0.89
Ascorbic acid uptake and regulation of type I collagen synthesis in cultured vascular smooth muscle cells. J Vasc Res (2008) 0.88
Assay of prolyl 4-hydroxylase by the chromatographic determination of [14C]succinic acid on ion-exchange minicolumns. Biochem J (1986) 0.88
The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster. Elife (2014) 0.85
Low iron status as a factor of increased bone resorption and effects of an iron and vitamin D-fortified skimmed milk on bone remodelling in young Spanish women. Eur J Nutr (2013) 0.84
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Relationship of circulating total homocysteine and C-reactive protein to trabecular bone in postmenopausal women. J Clin Densitom (2007) 0.83
Severe nutritional iron-deficiency anaemia has a negative effect on some bone turnover biomarkers in rats. Eur J Nutr (2011) 0.83
Ascorbate as a co-factor for fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression. Front Oncol (2014) 0.81
Stringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylase. PLoS One (2009) 0.81
Serum ferritin levels are positively associated with bone mineral density in elderly Korean men: the 2008-2010 Korea National Health and Nutrition Examination Surveys. J Bone Miner Metab (2013) 0.81
Oxygen concentration controls epigenetic effects in models of familial paraganglioma. PLoS One (2015) 0.80
Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein. Hypoxia (Auckl) (2013) 0.79
Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells. J Biol Chem (2015) 0.78
Changes in basic metabolic elements associated with the degeneration and ossification of ligamenta flava. J Spinal Cord Med (2008) 0.77
Assessment of the use of LED phototherapy on bone defects grafted with hydroxyapatite on rats with iron-deficiency anemia and nonanemic: a Raman spectroscopy analysis. Lasers Med Sci (2014) 0.77
Chronic iron deficiency as an emerging risk factor for osteoporosis: a hypothesis. Nutrients (2015) 0.76
Co-operative intermolecular kinetics of 2-oxoglutarate dependent dioxygenases may be essential for system-level regulation of plant cell physiology. Front Plant Sci (2015) 0.76
Synergistic effect of isoflavone glycosides and fructooligosaccharides on postgastrectomy osteopenia in rats. J Clin Biochem Nutr (2012) 0.76
Modeling dioxygenase enzyme kinetics in familial paraganglioma. Biol Open (2015) 0.75
Steady-state kinetic studies of the inhibitory action of Zn2+ on ribonuclease T1 catalysis. Biochem J (1982) 0.75
Dietary intakes of expeditioners during prolonged sunlight deprivation in polar enviroments do not support bone health. Int J Circumpolar Health (2015) 0.75
Does superoxide anion participate in 2-oxoglutarate-dependent hydroxylation? Biochem J (1982) 0.75
Succinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and Epigenetics. Int J Endocrinol (2015) 0.75
Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software. PMC Biophys (2010) 0.75
Collagens: molecular biology, diseases, and potentials for therapy. Annu Rev Biochem (1995) 5.52
Modifications of a specific assay for hydroxyproline in urine. Anal Biochem (1967) 5.48
Heritable diseases of collagen. N Engl J Med (1984) 4.39
The biosynthesis of collagen and its disorders (first of two parts). N Engl J Med (1979) 3.87
Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene. EMBO J (1987) 2.79
Posttranslational enzymes in the biosynthesis of collagen: intracellular enzymes. Methods Enzymol (1982) 2.77
The biosynthesis of collagen and its disorders (second of two parts). N Engl J Med (1979) 2.76
Demyelinating polyneuropathy in a patient with the tRNA(Leu)(UUR) mutation at base pair 3243 of the mitochondrial DNA. Neurology (1995) 2.05
Ultrastructural identification of extension aminopropeptides of type I and III collagens in human skin. Proc Natl Acad Sci U S A (1981) 2.03
Collagens and collagen-related diseases. Ann Med (2001) 1.98
A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase. J Biol Chem (1987) 1.92
An affinity-column procedure using poly(L-proline) for the purification of prolyl hydroxylase. Purification of the enzyme from chick embryos. Eur J Biochem (1975) 1.80
Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit. FASEB J (1989) 1.79
Mechanism of the prolyl hydroxylase reaction. 2. Kinetic analysis of the reaction sequence. Eur J Biochem (1977) 1.77
Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase. J Biol Chem (1986) 1.75
Detection of intracellular bacteria in the buds of Scotch pine (Pinus sylvestris L.) by in situ hybridization. Appl Environ Microbiol (2000) 1.73
Urinary excretion of hydroxyproline in health and disease. Int Rev Connect Tissue Res (1970) 1.70
Evidence for a structural mutation of procollagen type I in a patient with the Ehlers-Danlos syndrome type VII. J Biol Chem (1980) 1.69
The 2-oxoglutarate binding site of prolyl 4-hydroxylase. Identification of distinct subsites and evidence for 2-oxoglutarate decarboxylation in a ligand reaction at the enzyme-bound ferrous ion. Eur J Biochem (1984) 1.56
Ascorbate is consumed stoichiometrically in the uncoupled reactions catalyzed by prolyl 4-hydroxylase and lysyl hydroxylase. J Biol Chem (1984) 1.50
Gene expression of type I, III and IV collagens in hepatic fibrosis induced by dimethylnitrosamine in the rat. Biochem J (1987) 1.46
The role of ascorbate in the prolyl hydroxylase reaction. Biochem Biophys Res Commun (1978) 1.45
Biosynthesis of collagen and its alterations in pathological states. Med Biol (1976) 1.42
Further evaluation of the significance of urinary hydroxyproline determinations in the diagnosis of thyroid disorders. Clin Chim Acta (1968) 1.41
Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system. Proc Natl Acad Sci U S A (1992) 1.40
Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase. EMBO J (1997) 1.37
Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts. Proc Natl Acad Sci U S A (1989) 1.36
Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer. J Biol Chem (1997) 1.34
Assay of collagen-galactosyltransferase and collagen-glucosyltransferase activities and preliminary characterization of enzymic reactions with transferases from chick-embryo cartilage. Eur J Biochem (1975) 1.32
Studies on the lysyl hydroxylase reaction. I. Initial velocity kinetics and related aspects. Biochim Biophys Acta (1980) 1.31
Protocollagen proline hydroxylase activity in the skin of normal human subjects and of patients with scleroderma. Scand J Clin Lab Invest (1969) 1.30
Post-translational processing of procollagens. Ann N Y Acad Sci (1985) 1.30
Hydroxyproline in the serum and urine. Normal values and clinical significance. Acta Med Scand (1966) 1.30
Recent developments in posttranslational modification: intracellular processing. Methods Enzymol (1987) 1.29
Hydroxylation of proline in synthetic polypeptides with purified protocollagen hydroxylase. J Biol Chem (1967) 1.28
Partial purification and characterization of protocollagen lysine hydroxylase from chick embryos. Biochim Biophys Acta (1972) 1.28
ERp60 does not substitute for protein disulphide isomerase as the beta-subunit of prolyl 4-hydroxylase. Biochem J (1996) 1.27
Activities of prolyl hydroxylase, lysyl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase in the liver of rats with hepatic injury. Biochem J (1974) 1.25
Collagen glycosyltransferases. Int Rev Connect Tissue Res (1979) 1.25
Expression and site-directed mutagenesis of human protein disulfide isomerase in Escherichia coli. This multifunctional polypeptide has two independently acting catalytic sites for the isomerase activity. J Biol Chem (1992) 1.23
Synthesis and degradation of type I procollagen mRNAs in cultured human skin fibroblasts and the effect of cortisol. J Biol Chem (1985) 1.22
Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity. J Biol Chem (2000) 1.22
A homozygous stop codon in the lysyl hydroxylase gene in two siblings with Ehlers-Danlos syndrome type VI. Nat Genet (1992) 1.20
Partial purification and characterization of a neutral protease which cleaves the N-terminal propeptides from procollagen. Biochemistry (1978) 1.18
Molecular biology of prolyl 4-hydroxylase. Ann N Y Acad Sci (1990) 1.18
Radiommunoassay for human and chick prolyl hydroxylases. Eur J Biochem (1975) 1.17
Assessment of skin erythema by eye, laser Doppler flowmeter, spectroradiometer, two-channel erythema meter and Minolta chroma meter. Arch Dermatol Res (1993) 1.16
Human prolyl hydroxylase. Purification, partial characterization and preparation of antiserum to the enzyme. Eur J Biochem (1975) 1.16
Prolyl 3-hydroxylase: partial characterization of the enzyme from rat kidney cortex. Eur J Biochem (1977) 1.15
p-HMW-collagen, a minor collagen obtained from chick embryo cartilage without proteolytic treatment of the tissue. Eur J Biochem (1983) 1.14
Differences between collagen hydroxylases and 2-oxoglutarate dehydrogenase in their inhibition by structural analogues of 2-oxoglutarate. Biochem J (1985) 1.13
Molecular cloning of chick lysyl hydroxylase. Little homology in primary structure to the two types of subunit of prolyl 4-hydroxylase. J Biol Chem (1991) 1.12
Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3) J Biol Chem (1998) 1.12
Isolation of lysyl hydroxylase, an enzyme of collagen synthesis, from chick embryos as a homogeneous protein. Biochem J (1980) 1.11
Profiling of hot surfaces by pulsed time-of-flight laser range finder techniques. Appl Opt (1993) 1.11
Site-directed mutagenesis of human lysyl hydroxylase expressed in insect cells. Identification of histidine residues and an aspartic acid residue critical for catalytic activity. J Biol Chem (1996) 1.11
Cloning and characterization of a novel human lysyl hydroxylase isoform highly expressed in pancreas and muscle. J Biol Chem (1997) 1.11
Monoclonal antibodies to human prolyl 4-hydroxylase. Eur J Biochem (1984) 1.10
High-level production of human type I collagen in the yeast Pichia pastoris. Yeast (2001) 1.10
Posttranslational modifications in the biosynthesis of type IV collagen by a human tumor cell line. Biochemistry (1981) 1.09
Assay of protocollagen lysyl hydroxylase activity in the skin of human subjects and changes in the activity with age. Clin Chim Acta (1973) 1.08
Human placental lysyl oxidase. Purification, partial characterization, and preparation of two specific antisera to the enzyme. J Biol Chem (1984) 1.08
Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit. Proc Natl Acad Sci U S A (1995) 1.08
Partial purification and characterization of chick-embryo prolyl 3-hydroxylase. Biochem J (1979) 1.08
Studies on protocollagen lysine hydroxylase. Hydroxylation of synthetic peptides and the stoichiometric decarboxylation of -ketoglutarate. Biochemistry (1972) 1.07
Clinical significance of urinary hydroxyproline determinations in children. Ann Paediatr Fenn (1965) 1.07
Evidence for 4-hydroxyproline in viral proteins. Characterization of a viral prolyl 4-hydroxylase and its peptide substrates. J Biol Chem (1999) 1.07