Published in Biochem J on November 01, 1979
Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex. J Biol Chem (2009) 1.74
Null mutations in LEPRE1 and CRTAP cause severe recessive osteogenesis imperfecta. Cell Tissue Res (2009) 1.56
Differences between collagen hydroxylases and 2-oxoglutarate dehydrogenase in their inhibition by structural analogues of 2-oxoglutarate. Biochem J (1985) 1.13
Isolation of lysyl hydroxylase, an enzyme of collagen synthesis, from chick embryos as a homogeneous protein. Biochem J (1980) 1.11
Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex. Hum Mol Genet (2009) 1.07
The evolutionarily conserved leprecan gene: its regulation by Brachyury and its role in the developing Ciona notochord. Dev Biol (2009) 0.92
A role for prolyl 3-hydroxylase 2 in post-translational modification of fibril-forming collagens. J Biol Chem (2011) 0.89
Posttranslational modifications in type I collagen from different tissues extracted from wild type and prolyl 3-hydroxylase 1 null mice. J Biol Chem (2013) 0.88
Immunological characterization of lysyl hydroxylase, an enzyme of collagen synthesis. Biochem J (1981) 0.82
Co-operative intermolecular kinetics of 2-oxoglutarate dependent dioxygenases may be essential for system-level regulation of plant cell physiology. Front Plant Sci (2015) 0.76
Unity in diversity, a systems approach to regulating plant cell physiology by 2-oxoglutarate-dependent dioxygenases. Front Plant Sci (2015) 0.76
Effect of prevention of procollagen triple-helix formation on proline 3-hydroxylation in freshly isolated chick-embryo tendon cells. Biochem J (1981) 0.75
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. J Biol Chem (1969) 142.11
The primary structure of collagen. Int Rev Connect Tissue Res (1976) 3.92
An affinity-column procedure using poly(L-proline) for the purification of prolyl hydroxylase. Purification of the enzyme from chick embryos. Eur J Biochem (1975) 1.80
Mechanism of the prolyl hydroxylase reaction. 2. Kinetic analysis of the reaction sequence. Eur J Biochem (1977) 1.77
Enzymatic hydroxylation of proline and lysine in protocollagen. Proc Natl Acad Sci U S A (1967) 1.61
Affinity column purification of protocollagen proline hydroxylase from chick embryos and further characterization of the enzyme. J Biol Chem (1973) 1.58
Homology between a prolyl hydroxylase subunit and a tissue protein that crossreacts immunologically with the enzyme. Proc Natl Acad Sci U S A (1977) 1.30
Partial purification and characterization of protocollagen lysine hydroxylase from chick embryos. Biochim Biophys Acta (1972) 1.28
Human prolyl hydroxylase. Purification, partial characterization and preparation of antiserum to the enzyme. Eur J Biochem (1975) 1.16
Prolyl 3-hydroxylase: partial characterization of the enzyme from rat kidney cortex. Eur J Biochem (1977) 1.15
Lysyl hydroxylase. Further purification and characterization of the enzyme from chick embryos and chick embryo cartilage. Biochim Biophys Acta (1976) 1.06
Separation of prolyl 3-hydroxylase and 4-hydroxylase activities and the 4-hydroxyproline requirement for synthesis of 3-hydroxyproline. Biochem Biophys Res Commun (1976) 0.99
Affinity chromatography of lysyl hydroxylase on concanavalin A-agarose. Biochim Biophys Acta (1977) 0.98
A rapid assay for prolyl 3-hydroxylase activity. Anal Biochem (1978) 0.98
Effect of hepatic injury on prolyl 3-hydroxylase and 4-hydroxylase activities in rat liver and on immunoreactive prolyl 4-hydroxylase concentrations in the liver and serum. Biochem J (1978) 0.97
Prolyl 3-hydroxylase and 4-hydroxylase activities in certain rat and chick-embryo tissues and age-related changes in their activities in the rat. Biochem J (1979) 0.91
Concanavalin A binds of purified prolyl hydroxylase and partially inhibits its enzymic activity. Biochem Biophys Res Commun (1976) 0.90
Hydrophobic and carbohydrate-recognition chromatographies of collagen glucosyltransferase. Eur J Biochem (1977) 0.89
Affinity chromatography of collagen glycosyltransferases on collagen linked to agarose. Eur J Biochem (1976) 0.89
Protocollagen proline hydroxylase: molecular weight, subunits and isoelectric point. Biochim Biophys Acta (1970) 0.88
Isolation of collagen glucosyltransferase as a homogeneous protein from chick embryos. Biochim Biophys Acta (1977) 0.86
Glomerular basement membrane collagen and activities of the intracellular enzymes of collagen biosynthesis in congenital nephrotic syndrome of the Finnish type. Clin Chim Acta (1978) 0.83
Further characterization of collagen galactosyltransferase from chick embryos. Biochem J (1978) 0.81
Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome. Mol Cell (1998) 9.85
Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma. Biochemistry (1982) 6.87
Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature (1980) 5.84
Collagens: molecular biology, diseases, and potentials for therapy. Annu Rev Biochem (1995) 5.52
Modifications of a specific assay for hydroxyproline in urine. Anal Biochem (1967) 5.48
Heritable diseases of collagen. N Engl J Med (1984) 4.39
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I. Proc Natl Acad Sci U S A (2000) 4.22
Identification of mutations in the COL4A5 collagen gene in Alport syndrome. Science (1990) 4.15
The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet (2001) 4.00
The biosynthesis of collagen and its disorders (first of two parts). N Engl J Med (1979) 3.87
Nephrin is specifically located at the slit diaphragm of glomerular podocytes. Proc Natl Acad Sci U S A (1999) 3.77
Phylogenetic network for European mtDNA. Am J Hum Genet (2001) 3.26
Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy. Nat Genet (1995) 3.05
Type IV collagen: structure, gene organization, and role in human diseases. Molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis. J Biol Chem (1993) 2.89
Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene. EMBO J (1987) 2.79
Posttranslational enzymes in the biosynthesis of collagen: intracellular enzymes. Methods Enzymol (1982) 2.77
The biosynthesis of collagen and its disorders (second of two parts). N Engl J Med (1979) 2.76
X-linked Alport syndrome: natural history in 195 families and genotype- phenotype correlations in males. J Am Soc Nephrol (2000) 2.71
Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed. Science (1999) 2.62
Radioimmunoassay of the carboxyterminal propeptide of human type I procollagen. Clin Chem (1990) 2.51
Structure of the gene for congenital nephrotic syndrome of the finnish type (NPHS1) and characterization of mutations. Am J Hum Genet (1999) 2.44
Human laminin B1 chain. A multidomain protein with gene (LAMB1) locus in the q22 region of chromosome 7. J Biol Chem (1987) 2.36
Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell (1995) 2.34
cDNA clones coding for the pro-alpha1(IV) chain of human type IV procollagen reveal an unusual homology of amino acid sequences in two halves of the carboxyl-terminal domain. J Biol Chem (1985) 2.30
7-S collagen: characterization of an unusual basement membrane structure. Eur J Biochem (1980) 2.19
Monitoring of veno-occlusive disease after bone marrow transplantation by serum aminopropeptide of type III procollagen. Lancet (1993) 2.09
Role of the scavenger receptor MARCO in alveolar macrophage binding of unopsonized environmental particles. J Exp Med (1999) 2.08
Human laminin B2 chain. Comparison of the complete amino acid sequence with the B1 chain reveals variability in sequence homology between different structural domains. J Biol Chem (1988) 2.07
Demyelinating polyneuropathy in a patient with the tRNA(Leu)(UUR) mutation at base pair 3243 of the mitochondrial DNA. Neurology (1995) 2.05
Identification of a distinct type IV collagen alpha chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome. Proc Natl Acad Sci U S A (1990) 2.04
Collagens and collagen-related diseases. Ann Med (2001) 1.98
Macromolecular structure of basement membrane collagens. FEBS Lett (1981) 1.96
High expression of 92-kD type IV collagenase (gelatinase B) in the osteoclast lineage during mouse development. J Cell Biol (1994) 1.96
Collagen metabolism and growth in prepubertal children with asthma treated with inhaled steroids. J Pediatr (1998) 1.94
Collagen scar formation after acute myocardial infarction: relationships to infarct size, left ventricular function, and coronary artery patency. Circulation (1997) 1.93
Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res (1995) 1.93
A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase. J Biol Chem (1987) 1.92
Genome-wide scan for type 1 diabetic nephropathy in the Finnish population reveals suggestive linkage to a single locus on chromosome 3q. Kidney Int (2006) 1.91
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase. Biochem J (1989) 1.89
Effect of chronic renal failure on bone turnover and bone alkaline phosphatase isoforms. Kidney Int (2001) 1.88
The O75X adhesin of uropathogenic Escherichia coli is a type IV collagen-binding protein. Mol Microbiol (1989) 1.87
A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment. J Cell Biol (1992) 1.84
Mechanism of the prolyl hydroxylase reaction. 1. Role of co-substrates. Eur J Biochem (1977) 1.83
An affinity-column procedure using poly(L-proline) for the purification of prolyl hydroxylase. Purification of the enzyme from chick embryos. Eur J Biochem (1975) 1.80
The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers. Am J Pathol (1994) 1.79
Nephrin is involved in podocyte maturation but not survival during glomerular development. Kidney Int (2007) 1.79
Mechanism of the prolyl hydroxylase reaction. 2. Kinetic analysis of the reaction sequence. Eur J Biochem (1977) 1.77
Deletion of the paired alpha 5(IV) and alpha 6(IV) collagen genes in inherited smooth muscle tumors. Science (1993) 1.77
Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase. J Biol Chem (1986) 1.75
Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer. Am J Pathol (1993) 1.71
Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization. Cancer Res (1992) 1.71
Urinary excretion of hydroxyproline in health and disease. Int Rev Connect Tissue Res (1970) 1.70
The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation. J Bone Miner Res (2003) 1.68
Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells. J Biol Chem (1991) 1.68
Structure of the human type IV collagenase gene. J Biol Chem (1990) 1.68
Mutations in the gamma 2 chain gene (LAMC2) of kalinin/laminin 5 in the junctional forms of epidermolysis bullosa. Nat Genet (1994) 1.65
Congenital nephrotic syndrome (NPHS1): features resulting from different mutations in Finnish patients. Kidney Int (2000) 1.65
Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo. J Immunol (1999) 1.65
Herlitz's junctional epidermolysis bullosa is linked to mutations in the gene (LAMC2) for the gamma 2 subunit of nicein/kalinin (LAMININ-5). Nat Genet (1994) 1.63
A 3-year clinical follow-up of adult patients with 3243A>G in mitochondrial DNA. Neurology (2006) 1.58
Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry. J Bone Miner Res (1993) 1.57
Human laminin M chain (merosin): complete primary structure, chromosomal assignment, and expression of the M and A chain in human fetal tissues. J Cell Biol (1994) 1.57
Biosynthesis of type IV procollagens. Biochemistry (1980) 1.57
Nephrin redistribution on podocytes is a potential mechanism for proteinuria in patients with primary acquired nephrotic syndrome. Am J Pathol (2001) 1.57
High mutation detection rate in the COL4A5 collagen gene in suspected Alport syndrome using PCR and direct DNA sequencing. J Am Soc Nephrol (1998) 1.57
Markers of fibrogenesis and basement membrane formation in alcoholic liver disease. Relation to severity, presence of hepatitis, and alcohol intake. Gastroenterology (1990) 1.56
The 2-oxoglutarate binding site of prolyl 4-hydroxylase. Identification of distinct subsites and evidence for 2-oxoglutarate decarboxylation in a ligand reaction at the enzyme-bound ferrous ion. Eur J Biochem (1984) 1.56
Structural diversity and domain composition of a unique collagenous fragment (intima collagen) obtained from human placenta. Biochem J (1983) 1.55
Aberrant type I and type III collagen gene expression in human breast cancer in vivo. J Pathol (1998) 1.53
Ascorbate is consumed stoichiometrically in the uncoupled reactions catalyzed by prolyl 4-hydroxylase and lysyl hydroxylase. J Biol Chem (1984) 1.50
Partial purification and characterization of a neutral protease which cleaves type IV collagen. Biochemistry (1981) 1.49
CD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhere. Am J Physiol Renal Physiol (2000) 1.48
Congenital nephrotic syndrome of the Finnish type maps to the long arm of chromosome 19. Am J Hum Genet (1994) 1.47
Gene expression of type I, III and IV collagens in hepatic fibrosis induced by dimethylnitrosamine in the rat. Biochem J (1987) 1.46
A novel mitochondrial DNA mutation and a mutation in the Notch3 gene in a patient with myopathy and CADASIL. J Mol Med (Berl) (2001) 1.46
The role of ascorbate in the prolyl hydroxylase reaction. Biochem Biophys Res Commun (1978) 1.45
Phylogenetic network of the mtDNA haplogroup U in Northern Finland based on sequence analysis of the complete coding region by conformation-sensitive gel electrophoresis. Am J Hum Genet (2000) 1.45
Purification and characterization of a murine basement membrane collagen-degrading enzyme secreted by metastatic tumor cells. J Biol Chem (1983) 1.45
Biosynthesis of collagen and its alterations in pathological states. Med Biol (1976) 1.42
Further evaluation of the significance of urinary hydroxyproline determinations in the diagnosis of thyroid disorders. Clin Chim Acta (1968) 1.41
Collagen metabolites in the prediction of response to GH therapy in short children. Eur J Endocrinol (1997) 1.40
Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system. Proc Natl Acad Sci U S A (1992) 1.40
Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development. J Biol Chem (1992) 1.39
Mutation spectrum in the nephrin gene (NPHS1) in congenital nephrotic syndrome. Hum Mutat (2001) 1.38
Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase. EMBO J (1997) 1.37
Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states. Hum Mol Genet (2000) 1.37
Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4. Nat Neurosci (2001) 1.37
Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts. Proc Natl Acad Sci U S A (1989) 1.36
The structural genes for alpha 1 and alpha 2 chains of human type IV collagen are divergently encoded on opposite DNA strands and have an overlapping promoter region. J Biol Chem (1988) 1.35
Recombinant laminin-8 (alpha(4)beta(1)gamma(1)). Production, purification,and interactions with integrins. J Biol Chem (2000) 1.34
Serum concentration of the cross-linked carboxyterminal telopeptide of type I collagen (ICTP) is a useful prognostic indicator in multiple myeloma. Br J Cancer (1992) 1.34
Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer. J Biol Chem (1997) 1.34
Assay of collagen-galactosyltransferase and collagen-glucosyltransferase activities and preliminary characterization of enzymic reactions with transferases from chick-embryo cartilage. Eur J Biochem (1975) 1.32