Published in J Biol Chem on December 30, 2009
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell (2010) 2.92
The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states. Biochim Biophys Acta (2012) 1.32
The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation. Biochim Biophys Acta (2012) 1.11
The spt5 C-terminal region recruits yeast 3' RNA cleavage factor I. Mol Cell Biol (2012) 0.99
The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress. J Biol Chem (2010) 0.94
A role for SUMO in nucleotide excision repair. DNA Repair (Amst) (2011) 0.92
Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly. J Biol Chem (2011) 0.91
A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeast. PLoS One (2011) 0.89
Insights into how Spt5 functions in transcription elongation and repressing transcription coupled DNA repair. Nucleic Acids Res (2014) 0.87
A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation. Nat Commun (2014) 0.84
Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest. J Biol Chem (2016) 0.84
Ubiquitous transcription factors display structural plasticity and diverse functions: NusG proteins - Shifting shapes and paradigms. Bioessays (2015) 0.82
The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis. Nucleic Acids Res (2014) 0.82
Diverse roles of RNA polymerase II-associated factor 1 complex in different subpathways of nucleotide excision repair. J Biol Chem (2011) 0.81
Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5. Mol Cell Biol (2015) 0.81
Transcription bypass of DNA lesions enhances cell survival but attenuates transcription coupled DNA repair. Nucleic Acids Res (2014) 0.77
Sen1, the yeast homolog of human senataxin, plays a more direct role than Rad26 in transcription coupled DNA repair. Nucleic Acids Res (2016) 0.77
A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture. PLoS One (2013) 0.77
Rad26, the transcription-coupled repair factor in yeast, is required for removal of stalled RNA polymerase-II following UV irradiation. PLoS One (2013) 0.76
Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells. Oncotarget (2015) 0.75
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet (1984) 35.54
The Pfam protein families database. Nucleic Acids Res (2007) 30.53
STRING 8--a global view on proteins and their functional interactions in 630 organisms. Nucleic Acids Res (2008) 20.62
Molecular mechanism of transcription-repair coupling. Science (1993) 9.55
The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell (2003) 7.47
Phosphorylation and functions of the RNA polymerase II CTD. Genes Dev (2006) 7.44
Transcription-coupled DNA repair: two decades of progress and surprises. Nat Rev Mol Cell Biol (2008) 7.00
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dev (1998) 6.96
Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae. Genetics (1984) 5.64
Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev (1998) 5.16
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol Cell Biol (2002) 5.04
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell (1992) 4.80
Tackling the protease problem in Saccharomyces cerevisiae. Methods Enzymol (1991) 4.76
The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc Natl Acad Sci U S A (1990) 4.04
Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo. Mol Cell (2005) 4.00
Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects. Cell Res (2008) 3.83
Transcriptional regulation in the yeast GAL gene family: a complex genetic network. FASEB J (1995) 3.78
Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription. Proc Natl Acad Sci U S A (2003) 2.92
Subpathways of nucleotide excision repair and their regulation. Oncogene (2002) 2.92
P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation. Mol Cell (2006) 2.92
SPT4, SPT5 and SPT6 interactions: effects on transcription and viability in Saccharomyces cerevisiae. Genetics (1992) 2.92
Structure-based assembly of protein complexes in yeast. Science (2004) 2.89
SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat. Mol Cell Biol (1991) 2.89
Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo. Mol Cell (2006) 2.84
Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation. Eur J Biochem (2003) 2.74
Domains in the SPT5 protein that modulate its transcriptional regulatory properties. Mol Cell Biol (2000) 2.74
Interactions of Isw2 chromatin remodeling complex with nucleosomal arrays: analyses using recombinant yeast histones and immobilized templates. Mol Cell Biol (2001) 2.63
Structures of complete RNA polymerase II and its subcomplex, Rpb4/7. J Biol Chem (2004) 2.52
Connections between mRNA 3' end processing and transcription termination. Curr Opin Cell Biol (2005) 2.46
RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6. EMBO J (1994) 2.46
Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells. Nucleic Acids Res (1993) 2.45
The RAD7 and RAD16 genes, which are essential for pyrimidine dimer removal from the silent mating type loci, are also required for repair of the nontranscribed strand of an active gene in Saccharomyces cerevisiae. Mol Cell Biol (1994) 2.26
Structure and function of the human transcription elongation factor DSIF. J Biol Chem (1999) 2.19
Cockayne syndrome group B protein enhances elongation by RNA polymerase II. Proc Natl Acad Sci U S A (1997) 2.16
Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. J Biol Chem (1997) 2.12
Bur1 kinase is required for efficient transcription elongation by RNA polymerase II. Mol Cell Biol (2003) 2.08
Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters. Mol Cell (2009) 2.08
Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex. Mol Cell Biol (2009) 1.82
Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5. Proc Natl Acad Sci U S A (2009) 1.73
Yeast carboxyl-terminal domain kinase I positively and negatively regulates RNA polymerase II carboxyl-terminal domain phosphorylation. J Biol Chem (1999) 1.69
Mechanisms of transcription-repair coupling and mutation frequency decline. Microbiol Rev (1994) 1.68
Double mutants of Saccharomyces cerevisiae with alterations in global genome and transcription-coupled repair. Mol Cell Biol (1996) 1.57
Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J (2003) 1.48
Molecular and genetic characterization of SPT4, a gene important for transcription initiation in Saccharomyces cerevisiae. Mol Gen Genet (1993) 1.38
Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiae. EMBO J (2002) 1.36
Bur1/Bur2 and the Ctk complex in yeast: the split personality of mammalian P-TEFb. Cell Cycle (2006) 1.31
Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation. Structure (2008) 1.30
BUR1 and BUR2 encode a divergent cyclin-dependent kinase-cyclin complex important for transcription in vivo. Mol Cell Biol (2000) 1.28
RAD26, the yeast homolog of human Cockayne's syndrome group B gene, encodes a DNA-dependent ATPase. J Biol Chem (1996) 1.25
Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. EMBO J (2006) 1.24
Requirement for yeast RAD26, a homolog of the human CSB gene, in elongation by RNA polymerase II. Mol Cell Biol (2001) 1.22
The NEF4 complex regulates Rad4 levels and utilizes Snf2/Swi2-related ATPase activity for nucleotide excision repair. Mol Cell Biol (2004) 1.17
Spt4 modulates Rad26 requirement in transcription-coupled nucleotide excision repair. EMBO J (2000) 1.11
Dissecting transcription-coupled and global genomic repair in the chromatin of yeast GAL1-10 genes. J Biol Chem (2004) 1.11
Low- and high-resolution mapping of DNA damage at specific sites. Methods (2000) 1.10
ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol (2007) 1.09
Inhibitors of macromolecular synthesis in yeast. Methods Cell Biol (1975) 1.08
Requirement of ELC1 for RNA polymerase II polyubiquitylation and degradation in response to DNA damage in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.05
The DNA-dependent ATPase activity of yeast nucleotide excision repair factor 4 and its role in DNA damage recognition. J Biol Chem (1998) 1.05
Nucleotide level detection of cyclobutane pyrimidine dimers using oligonucleotides and magnetic beads to facilitate labelling of DNA fragments incised at the dimers and chemical sequencing reference ladders. Carcinogenesis (1996) 1.01
The genetic defect in the Chinese hamster ovary cell mutant UV61 permits moderate selective repair of cyclobutane pyrimidine dimers in an expressed gene. Mutat Res (1991) 0.98
DSIF contributes to transcriptional activation by DNA-binding activators by preventing pausing during transcription elongation. Nucleic Acids Res (2007) 0.92
Control of eukaryotic transcription elongation. Genome Biol (2001) 0.92
Yeast Rpb9 plays an important role in ubiquitylation and degradation of Rpb1 in response to UV-induced DNA damage. Mol Cell Biol (2007) 0.89
Evidence that the transcription elongation function of Rpb9 is involved in transcription-coupled DNA repair in Saccharomyces cerevisiae. Mol Cell Biol (2006) 0.88
Modulation of Rad26- and Rpb9-mediated DNA repair by different promoter elements. J Biol Chem (2006) 0.84
Yeast Elc1 plays an important role in global genomic repair but not in transcription coupled repair. DNA Repair (Amst) (2008) 0.82
Transcription elongation factor Spt4 mediates loss of phosphorylated RNA polymerase II transcription in response to DNA damage. Nucleic Acids Res (2002) 0.79
Tfb5 is partially dispensable for Rad26 mediated transcription coupled nucleotide excision repair in yeast. DNA Repair (Amst) (2007) 0.76
Surface and interference coenhanced Raman scattering of graphene. ACS Nano (2009) 1.06
Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79. J Biol Chem (2011) 0.95
(+)-Myristinins A and D from Knema elegans, which inhibit DNA polymerase beta and cleave DNA. J Nat Prod (2005) 0.95
High temperature selective growth of single-walled carbon nanotubes with a narrow chirality distribution from a CoPt bimetallic catalyst. Chem Commun (Camb) (2012) 0.92
Metal-catalyst-free growth of single-walled carbon nanotubes. J Am Chem Soc (2009) 0.90
Yeast Rpb9 plays an important role in ubiquitylation and degradation of Rpb1 in response to UV-induced DNA damage. Mol Cell Biol (2007) 0.89
Rpb1 sumoylation in response to UV radiation or transcriptional impairment in yeast. PLoS One (2009) 0.87
Diagnosis and treatment of nine cases with carotid artery rupture due to hypopharyngeal and cervical esophageal foreign body ingestion. Eur Arch Otorhinolaryngol (2012) 0.86
The roles of Rad16 and Rad26 in repairing repressed and actively transcribed genes in yeast. DNA Repair (Amst) (2007) 0.84
Yeast Elc1 plays an important role in global genomic repair but not in transcription coupled repair. DNA Repair (Amst) (2008) 0.82
Diverse roles of RNA polymerase II-associated factor 1 complex in different subpathways of nucleotide excision repair. J Biol Chem (2011) 0.81
Bulk synthesis of large diameter semiconducting single-walled carbon nanotubes by oxygen-assisted floating catalyst chemical vapor deposition. J Am Chem Soc (2011) 0.79
[The study on clinical significance of the expression of EGFL7 in laryngeal squamous cell carcinoma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2013) 0.78
[CD44 regulates epithelial-mesenchymal transition and metastasis in nasopharyngeal cancer cells]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2013) 0.77
Tfb5 is partially dispensable for Rad26 mediated transcription coupled nucleotide excision repair in yeast. DNA Repair (Amst) (2007) 0.76
Growth velocity and direct length-sorted growth of short single-walled carbon nanotubes by a metal-catalyst-free chemical vapor deposition process. ACS Nano (2009) 0.76
DNA polymerase beta lyase inhibitors from Maytenus putterlickoides. J Nat Prod (2004) 0.75
[Synergistic interactions of TRAIL and paclitaxel on the nasopharyngeal carcinoma cell lines in vitro]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2012) 0.75
[The vitro research of effects of Beclin1 on paclitaxel-sensitivity in laryngeal carcinoma cell Hep-2]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2015) 0.75
[One case report of carotid body tumor resected with hemorrhage and artery repair]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2013) 0.75
Tunable Chemical Coupling in Two-Dimensional van der Waals-Electrostatic Heterostructures. ACS Nano (2019) 0.75