Connections between mRNA 3' end processing and transcription termination.

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1. Nat Genet (2008) 4.44

Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation. Nucleic Acids Res (2009) 3.44

The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model. Genes Dev (2006) 3.36

The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain. Nat Struct Mol Biol (2008) 3.17

3' end mRNA processing: molecular mechanisms and implications for health and disease. EMBO J (2008) 2.67

Transcription termination by nuclear RNA polymerases. Genes Dev (2009) 2.65

Papillomavirus genome structure, expression, and post-transcriptional regulation. Front Biosci (2006) 2.56

The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination. Genes Dev (2007) 2.49

MicroRNA assassins: factors that regulate the disappearance of miRNAs. Nat Struct Mol Biol (2010) 2.42

Functional integration of transcriptional and RNA processing machineries. Curr Opin Cell Biol (2008) 2.38

Formation of the 3' end of histone mRNA: getting closer to the end. Gene (2007) 2.07

A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3' end RNA polyadenylation. Genome Res (2008) 2.01

Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1. Nature (2009) 1.83

Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus. Chromosoma (2008) 1.69

Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination. Genes Dev (2008) 1.64

Transcription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly. Mol Cell (2007) 1.59

Coupled RNA processing and transcription of intergenic primary microRNAs. Mol Cell Biol (2009) 1.54

The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability. Mol Biol Cell (2008) 1.51

Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants. EMBO J (2007) 1.51

Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae. Mol Cell (2009) 1.50

cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II. Mol Cell Biol (2006) 1.47

A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint. Genes Dev (2009) 1.42

Transcriptional activity regulates alternative cleavage and polyadenylation. Mol Syst Biol (2011) 1.41

A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs. Mol Cell (2009) 1.35

RNA polymerase II C-terminal domain: Tethering transcription to transcript and template. Chem Rev (2013) 1.35

The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathway. Mol Cell (2009) 1.35

RNA polymerase II kinetics in polo polyadenylation signal selection. EMBO J (2011) 1.34

Phylogenetic analysis of mRNA polyadenylation sites reveals a role of transposable elements in evolution of the 3'-end of genes. Nucleic Acids Res (2008) 1.33

Properties of an intergenic terminator and start site switch that regulate IMD2 transcription in yeast. Mol Cell Biol (2008) 1.33

Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II. Eukaryot Cell (2008) 1.32

RNA processing and export. Cold Spring Harb Perspect Biol (2010) 1.22

Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. BMC Genomics (2008) 1.20

Early evolution of histone mRNA 3' end processing. RNA (2007) 1.20

Polyadenylation site choice in yeast is affected by competition between Npl3 and polyadenylation factor CFI. RNA (2007) 1.18

Role for the Ssu72 C-terminal domain phosphatase in RNA polymerase II transcription elongation. Mol Cell Biol (2006) 1.17

An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination. Mol Cell Biol (2006) 1.14

RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion. J Biol Chem (2009) 1.12

Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity. Nat Struct Mol Biol (2012) 1.08

Emerging Views on the CTD Code. Genet Res Int (2012) 1.08

RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts. PLoS One (2012) 1.06

Updating the CTD Story: From Tail to Epic. Genet Res Int (2011) 1.06

Studies of the 5' exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing. Mol Cell Biol (2008) 1.06

Genes involved in pre-mRNA 3'-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screen. Proc Natl Acad Sci U S A (2008) 1.05

abd-A regulation by the iab-8 noncoding RNA. PLoS Genet (2012) 1.04

Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression. Genes Dev (2007) 1.04

Evidence that the localization of the elongation factor Spt16 across transcribed genes is dependent upon histone H3 integrity in Saccharomyces cerevisiae. Genetics (2007) 1.04

Functional interaction of the Ess1 prolyl isomerase with components of the RNA polymerase II initiation and termination machineries. Mol Cell Biol (2009) 1.03

Genome-wide control of polyadenylation site choice by CPSF30 in Arabidopsis. Plant Cell (2012) 1.02

Histone gene expression and histone mRNA 3' end structure in Caenorhabditis elegans. BMC Mol Biol (2007) 1.01

Assembly of an export-competent mRNP is needed for efficient release of the 3'-end processing complex after polyadenylation. Mol Cell Biol (2009) 1.01

The C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair. J Biol Chem (2009) 1.01

Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes. Nat Commun (2014) 1.01

A new connection of mRNP biogenesis and export with transcription-coupled repair. Nucleic Acids Res (2007) 0.96

CHD chromatin remodelers and the transcription cycle. Transcription (2011) 0.94

Coupling mRNA synthesis and decay. Mol Cell Biol (2014) 0.92

Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Res (2010) 0.92

Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs. Nucleic Acids Res (2009) 0.92

Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription. J Biol Chem (2013) 0.92

Distinct polyadenylation landscapes of diverse human tissues revealed by a modified PA-seq strategy. BMC Genomics (2013) 0.92

Sub1 globally regulates RNA polymerase II C-terminal domain phosphorylation. Mol Cell Biol (2010) 0.91

Single-molecule studies of transcription: from one RNA polymerase at a time to the gene expression profile of a cell. J Mol Biol (2011) 0.91

Recruitment of mRNA cleavage/polyadenylation machinery by the yeast chromatin protein Sin1p/Spt2p. Proc Natl Acad Sci U S A (2006) 0.90

Regulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex. RNA (2009) 0.90

Genome-wide mapping of yeast RNA polymerase II termination. PLoS Genet (2014) 0.88

The hinge domain of the cleavage stimulation factor protein CstF-64 is essential for CstF-77 interaction, nuclear localization, and polyadenylation. J Biol Chem (2009) 0.88

Deletion of the nuclear exosome component RRP6 leads to continued accumulation of the histone mRNA HTB1 in S-phase of the cell cycle in Saccharomyces cerevisiae. Nucleic Acids Res (2007) 0.87

The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis. RNA (2008) 0.87

Spermatogenetic but not immunological defects in mice lacking the τCstF-64 polyadenylation protein. J Reprod Immunol (2011) 0.86

Mechanisms of HIV Transcriptional Regulation and Their Contribution to Latency. Mol Biol Int (2012) 0.86

Rhn1, a nuclear protein, is required for suppression of meiotic mRNAs in mitotically dividing fission yeast. PLoS One (2012) 0.85

Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p. Nucleic Acids Res (2010) 0.85

New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation. Mol Cell Biol (2010) 0.85

The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. J Biol Chem (2013) 0.85

How to stop: the mysterious links among RNA polymerase II occupancy 3' of genes, mRNA 3' processing and termination. Transcription (2012) 0.84

Fcp1 dephosphorylation of the RNA polymerase II C-terminal domain is required for efficient transcription of heat shock genes. Mol Cell Biol (2012) 0.83

Regulation of the catalytic function of topoisomerase II alpha through association with RNA. Nucleic Acids Res (2008) 0.83

Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies. Plant Physiol (2009) 0.83

Expression of bacterial Rho factor in yeast identifies new factors involved in the functional interplay between transcription and mRNP biogenesis. Mol Cell Biol (2009) 0.83

The role of Ctk1 kinase in termination of small non-coding RNAs. PLoS One (2013) 0.82

Mining Functional Elements in Messenger RNAs: Overview, Challenges, and Perspectives. Front Plant Sci (2011) 0.82

Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue. Cell Rep (2016) 0.81

RNA polymerase II mutations conferring defects in poly(A) site cleavage and termination in Saccharomyces cerevisiae. G3 (Bethesda) (2013) 0.79

A novel plant in vitro assay system for pre-mRNA cleavage during 3'-end formation. Plant Physiol (2011) 0.79

A manganese-dependent ribozyme in the 3'-untranslated region of Xenopus Vg1 mRNA. Nucleic Acids Res (2008) 0.77

TRAP150 activates splicing in composite terminal exons. Nucleic Acids Res (2014) 0.76

Sub1 contacts the RNA polymerase II stalk to modulate mRNA synthesis. Nucleic Acids Res (2016) 0.75

The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun (2017) 0.75

Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end. Pflugers Arch (2016) 0.75

Chromatin remodelers: We are the drivers!! Nucleus (2016) 0.75

Roles of Sumoylation in mRNA Processing and Metabolism. Adv Exp Med Biol (2017) 0.75

Genomewide Analysis of Clp1 Function in Transcription in Budding Yeast. Sci Rep (2017) 0.75