Published in J Funct Foods on January 01, 2009
Novel norcantharidin-loaded liver targeting chitosan nanoparticles to enhance intestinal absorption. Int J Nanomedicine (2012) 0.80
Anthocyanin Absorption and Metabolism by Human Intestinal Caco-2 Cells--A Review. Int J Mol Sci (2015) 0.79
MK571 inhibits phase-2 conjugation of flavonols by Caco-2/TC7 cells, but does not specifically inhibit their apical efflux. Biochem Pharmacol (2015) 0.77
Molecular structure-function relationship of dietary polyphenols for inhibiting VEGF-induced VEGFR-2 activity. Mol Nutr Food Res (2015) 0.76
Exploration of the protection of riboflavin laurate on oral mucositis induced by chemotherapy or radiotherapy at the cellular level: what is the leading contributor? Int J Mol Sci (2013) 0.75
Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials. Am J Clin Nutr (2008) 3.84
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport. Mol Pharmacol (2004) 1.50
Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. Eur J Nutr (2003) 1.40
Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin. Free Radic Res (2001) 1.38
Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants. Curr Opin Biotechnol (2008) 1.36
Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J Pharmacol Exp Ther (2003) 1.35
Metabolism of flavonoids via enteric recycling: mechanistic studies of disposition of apigenin in the Caco-2 cell culture model. J Pharmacol Exp Ther (2003) 1.32
Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2. Biochem Pharmacol (1999) 1.25
Effect of variety, processing, and storage on the flavonoid glycoside content and composition of lettuce and endive. J Agric Food Chem (2000) 1.22
Disposition and metabolism of the flavonoid chrysin in normal volunteers. Br J Clin Pharmacol (2001) 1.21
Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Res (2004) 1.20
Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells. Biochem Pharmacol (1998) 1.18
Conjugation position of quercetin glucuronides and effect on biological activity. Free Radic Biol Med (2000) 1.17
The small intestine can both absorb and glucuronidate luminal flavonoids. FEBS Lett (1999) 1.15
Cellular uptake of dietary flavonoid quercetin 4'-beta-glucoside by sodium-dependent glucose transporter SGLT1. J Pharmacol Exp Ther (2000) 1.14
Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism. Biochem Pharmacol (2003) 1.13
Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. J Pharmacol Exp Ther (2003) 1.13
Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo. Drug Metab Dispos (2003) 1.10
Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2. Pharm Res (2001) 1.06
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. Mol Pharmacol (2001) 1.06
Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin. Free Radic Biol Med (2001) 1.05
Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites. Biochem J (2003) 1.04
Absorption of kaempferol from endive, a source of kaempferol-3-glucuronide, in humans. Eur J Clin Nutr (2004) 1.03
Efflux of dietary flavonoid quercetin 4'-beta-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2. J Pharmacol Exp Ther (2000) 1.01
Bioavailabilities of quercetin-3-glucoside and quercetin-4'-glucoside do not differ in humans. J Nutr (2000) 1.00
Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells--potential role in carcinogen bioinactivation. Pharm Res (2001) 1.00
Epicatechin and catechin are O-methylated and glucuronidated in the small intestine. Biochem Biophys Res Commun (2000) 1.00
Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity. Bioorg Med Chem (2005) 0.99
Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway. J Nutr (2000) 0.99
Quercetin glucuronides but not glucosides are present in human plasma after consumption of quercetin-3-glucoside or quercetin-4'-glucoside. J Nutr (2001) 0.99
Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2. Arch Biochem Biophys (2000) 0.93
Identification of isomeric flavonoid glucuronides in urine and plasma by metal complexation and LC-ESI-MS/MS. J Mass Spectrom (2006) 0.92
Resveratrol transport and metabolism by human intestinal Caco-2 cells. J Pharm Pharmacol (2003) 0.90
Evaluation of the first-pass glucuronidation of selected flavones in gut by Caco-2 monolayer model. J Pharm Pharm Sci (2004) 0.89
Comparison of the intestinal absorption of quercetin, phloretin and their glucosides in rats. J Nutr (2001) 0.89
Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Mol Pharmacol (2005) 0.86
Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells. J Agric Food Chem (2005) 0.85
The splanchnic metabolism of flavonoids highly differed according to the nature of the compound. Am J Physiol Gastrointest Liver Physiol (2003) 0.82
Anti-complement activity of constituents from the stem-bark of Juglans mandshurica. Biol Pharm Bull (2003) 0.82
Propolis from the northwest of Argentina as a source of antifungal principles. J Appl Microbiol (2006) 0.81
Transcellular transport of genistein, a soybean-derived isoflavone, across human colon carcinoma cell line (Caco-2). Biopharm Drug Dispos (2001) 0.79
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr (2005) 6.05
Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials. Am J Clin Nutr (2008) 3.84
Amino acid addition to Vibrio cholerae LPS establishes a link between surface remodeling in gram-positive and gram-negative bacteria. Proc Natl Acad Sci U S A (2012) 1.83
Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am J Clin Nutr (2012) 1.78
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation. J Am Chem Soc (2013) 1.69
Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31-June 1, 2005, Washington, DC. J Nutr (2007) 1.66
Nutrigenomics and nutrigenetics: the emerging faces of nutrition. FASEB J (2005) 1.59
Understanding antimicrobial activities of phytochemicals against multidrug resistant bacteria and biofilms. Nat Prod Rep (2009) 1.55
A review of the health effects of green tea catechins in in vivo animal models. J Nutr (2004) 1.54
Characterization of green fluorescent proteins by 193 nm ultraviolet photodissociation mass spectrometry. Proteomics (2014) 1.50
Flavan-3-ol-enriched dark chocolate and white chocolate improve acute measures of platelet function in a gender-specific way--a randomized-controlled human intervention trial. Mol Nutr Food Res (2012) 1.43
Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique. Am J Clin Nutr (2013) 1.41
Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. Eur J Nutr (2003) 1.40
Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a (13)C-tracer study. Am J Clin Nutr (2013) 1.39
Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants. Curr Opin Biotechnol (2008) 1.36
How should we assess the effects of exposure to dietary polyphenols in vitro? Am J Clin Nutr (2004) 1.33
A critical review of the bioavailability of glucosinolates and related compounds. Nat Prod Rep (2004) 1.32
Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L. (horseradish tree) and Moringa stenopetala L. J Agric Food Chem (2003) 1.30
Cocoa and health: a decade of research. Br J Nutr (2007) 1.30
Chromogenic cross-linker for the characterization of protein structure by infrared multiphoton dissociation mass spectrometry. Anal Chem (2008) 1.28
Bioavailability of phyto-oestrogens. Br J Nutr (2003) 1.28
The dual nature of the wheat xylanase protein inhibitor XIP-I: structural basis for the inhibition of family 10 and family 11 xylanases. J Biol Chem (2004) 1.26
Identification of the major glucosinolate (4-mercaptobutyl glucosinolate) in leaves of Eruca sativa L. (salad rocket). Phytochemistry (2002) 1.24
Ultrafast ultraviolet photodissociation at 193 nm and its applicability to proteomic workflows. J Proteome Res (2010) 1.23
Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription. Mutat Res (2004) 1.21
Relative impact of flavonoid composition, dose and structure on vascular function: a systematic review of randomised controlled trials of flavonoid-rich food products. Mol Nutr Food Res (2012) 1.20
Chocolate intake increases urinary excretion of polyphenol-derived phenolic acids in healthy human subjects. Am J Clin Nutr (2003) 1.17
Infrared photoactivation reduces peptide folding and hydrogen-atom migration following ETD tandem mass spectrometry. Angew Chem Int Ed Engl (2009) 1.17
Review of the factors affecting bioavailability of soy isoflavones in humans. Nutr Cancer (2007) 1.16
Tyrosine sulfation in a Gram-negative bacterium. Nat Commun (2012) 1.13
Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism. Biochem Pharmacol (2003) 1.13
Isolation, identification and stability of acylated derivatives of apigenin 7-O-glucoside from chamomile (Chamomilla recutita [L.] Rauschert). Phytochemistry (2004) 1.12
Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women. Proc Nutr Soc (2006) 1.12
193-nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization. Proteomics (2011) 1.11
Simplifying fragmentation patterns of multiply charged peptides by N-terminal derivatization and electron transfer collision activated dissociation. Anal Chem (2009) 1.11
Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy-acyltransferase and its role in innate immune recognition. Mol Microbiol (2011) 1.10
Absorption, metabolism and excretion of flavanones from single portions of orange fruit and juice and effects of anthropometric variables and contraceptive pill use on flavanone excretion. Br J Nutr (2009) 1.10
Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo. Drug Metab Dispos (2003) 1.10
Comparison of infrared multiphoton dissociation and collision-induced dissociation of supercharged peptides in ion traps. J Am Soc Mass Spectrom (2008) 1.10
Implementing photodissociation in an Orbitrap mass spectrometer. J Am Soc Mass Spectrom (2011) 1.09
Identification and quantification of polyphenolic compounds in Longan (Euphoria longana Lam.) fruit. J Agric Food Chem (2005) 1.09
The first pilot project of the consortium for top-down proteomics: a status report. Proteomics (2014) 1.08
Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells. Mol Nutr Food Res (2010) 1.08
Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activity. Biochem Pharmacol (2007) 1.07
Bioavailability is improved by enzymatic modification of the citrus flavonoid hesperidin in humans: a randomized, double-blind, crossover trial. J Nutr (2006) 1.06
Urinary metabolites as biomarkers of polyphenol intake in humans: a systematic review. Am J Clin Nutr (2010) 1.06
Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter. Biochem Pharmacol (2003) 1.06
Cocoa procyanidins are stable during gastric transit in humans. Am J Clin Nutr (2002) 1.05
ESI-MS, DFT, and synthetic studies on the H(2)-mediated coupling of acetylene: insertion of C=X bonds into rhodacyclopentadienes and Brønsted acid cocatalyzed hydrogenolysis of organorhodium intermediates. J Am Chem Soc (2009) 1.05
IR and UV photodissociation as analytical tools for characterizing lipid A structures. Anal Chem (2011) 1.04
Impact of commensal microbiota on murine gastrointestinal tract gene ontologies. Physiol Genomics (2004) 1.04
Flavonoids for controlling starch digestion: structural requirements for inhibiting human alpha-amylase. J Med Chem (2008) 1.03
The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products. Mol Nutr Food Res (2009) 1.03
Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc and selenium. Br J Nutr (2006) 1.02
Bioavailability of chlorogenic acids following acute ingestion of coffee by humans with an ileostomy. Arch Biochem Biophys (2010) 1.02
Anatomical, chemical, and biochemical characterization of cladodes from prickly pear [Opuntia ficus-indica (L.) Mill.]. J Agric Food Chem (2009) 1.02
Ontogenic profiling of glucosinolates, flavonoids, and other secondary metabolites in Eruca sativa (salad rocket), Diplotaxis erucoides (wall rocket), Diplotaxis tenuifolia (wild rocket), and Bunias orientalis (Turkish rocket). J Agric Food Chem (2006) 1.01
Infrared multiphoton dissociation of peptide cations in a dual pressure linear ion trap mass spectrometer. Anal Chem (2009) 1.01
Metabolism and transport of the citrus flavonoid hesperetin in Caco-2 cell monolayers. Drug Metab Dispos (2008) 1.00
Isothiocyanate concentrations and interconversion of sulforaphane to erucin in human subjects after consumption of commercial frozen broccoli compared to fresh broccoli. Mol Nutr Food Res (2012) 1.00
Intact glucosinolate analysis in plant extracts by programmed cone voltage electrospray LC/MS: performance and comparison with LC/MS/MS methods. Anal Biochem (2002) 0.99
Bioavailability and metabolism. Mol Aspects Med (2002) 0.99
Composition of European chestnut (Castanea sativa Mill.) and association with health effects: fresh and processed products. J Sci Food Agric (2010) 0.99
Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells. Carcinogenesis (2004) 0.98
EptC of Campylobacter jejuni mediates phenotypes involved in host interactions and virulence. Infect Immun (2012) 0.98
Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy. Mol Nutr Food Res (2010) 0.97
Collisionally activated dissociation and infrared multiphoton dissociation of oligonucleotides in a quadrupole ion trap. Anal Biochem (2004) 0.97
XIP-I, a xylanase inhibitor protein from wheat: a novel protein function. Biochim Biophys Acta (2004) 0.97
Differentiation of phosphorylated and unphosphorylated peptides by high-performance liquid chromatography-electrospray ionization-infrared multiphoton dissociation in a quadrupole ion trap. Anal Chem (2005) 0.96
Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption. Drug Metab Dispos (2009) 0.95
Characterization of unique modification of flagellar rod protein FlgG by Campylobacter jejuni lipid A phosphoethanolamine transferase, linking bacterial locomotion and antimicrobial peptide resistance. J Biol Chem (2011) 0.95
Properties of quercetin conjugates: modulation of LDL oxidation and binding to human serum albumin. Free Radic Res (2004) 0.95
Rapid reversed phase ultra-performance liquid chromatography analysis of the major cocoa polyphenols and inter-relationships of their concentrations in chocolate. J Agric Food Chem (2007) 0.95
Evaluation of binding of perylene diimide and benzannulated perylene diimide ligands to DNA by electrospray ionization mass spectrometry. J Am Soc Mass Spectrom (2006) 0.94
Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells. Carcinogenesis (2002) 0.94
Specific characterization of substrate and inhibitor binding sites of a glycosyl hydrolase family 11 xylanase from Aspergillus niger. J Biol Chem (2002) 0.94
193 nm ultraviolet photodissociation of deprotonated sialylated oligosaccharides. Anal Chem (2011) 0.94
Ultraviolet photodissociation for characterization of whole proteins on a chromatographic time scale. Anal Chem (2014) 0.94
Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans. Free Radic Biol Med (2012) 0.93
Functional expression of human liver cytosolic beta-glucosidase in Pichia pastoris. Insights into its role in the metabolism of dietary glucosides. Eur J Biochem (2002) 0.93
Interactions affecting the bioavailability of dietary polyphenols in vivo. Int J Vitam Nutr Res (2007) 0.92
Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes. Carcinogenesis (2003) 0.92
Occurrence of proteinaceous endoxylanase inhibitors in cereals. Biochim Biophys Acta (2004) 0.92
Identification of isomeric flavonoid glucuronides in urine and plasma by metal complexation and LC-ESI-MS/MS. J Mass Spectrom (2006) 0.92
Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence. Biochemistry (2012) 0.92
Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans. J Nutr (2002) 0.92
Screening of threading bis-intercalators binding to duplex DNA by electrospray ionization tandem mass spectrometry. J Am Soc Mass Spectrom (2006) 0.91
Enhancement of ultraviolet photodissociation efficiencies through attachment of aromatic chromophores. Anal Chem (2010) 0.91