Published in Wiley Interdiscip Rev Nanomed Nanobiotechnol on January 05, 2010
Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges. Pharmaceuticals (Basel) (2013) 1.21
Polymeric conjugates for drug delivery. Chem Mater (2012) 1.06
Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic. Mol Pharm (2012) 0.92
Photochemical release of methotrexate from folate receptor-targeting PAMAM dendrimer nanoconjugate. Photochem Photobiol Sci (2012) 0.91
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. Eur J Med Chem (2011) 0.91
Recent advances in engineering polyvalent biological interactions. Biomacromolecules (2014) 0.86
A photochemical approach for controlled drug release in targeted drug delivery. Bioorg Med Chem (2011) 0.85
Mechanisms and implications of dual-acting methotrexate in folate-targeted nanotherapeutic delivery. Int J Mol Sci (2015) 0.84
Silica-based mesoporous nanoparticles for controlled drug delivery. J Tissue Eng (2013) 0.83
Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent. Bioorg Med Chem (2011) 0.82
Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic. Curr Pharm Des (2013) 0.80
Recent Developments in Active Tumor Targeted Multifunctional Nanoparticles for Combination Chemotherapy in Cancer Treatment and Imaging. J Biomed Nanotechnol (2015) 0.80
Biophysical characterization of a riboflavin-conjugated dendrimer platform for targeted drug delivery. Biomacromolecules (2012) 0.78
Light-controlled active release of photocaged ciprofloxacin for lipopolysaccharide-targeted drug delivery using dendrimer conjugates. Chem Commun (Camb) (2016) 0.77
Dendritic Guanidines as Efficient Analogues of Cell Penetrating Peptides. Pharmaceuticals (Basel) (2010) 0.77
Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res (2005) 4.71
An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J Immunol Methods (1991) 4.55
Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. J Biol Chem (1988) 2.44
Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy. J Med Chem (2005) 2.32
Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor. Pharm Res (2002) 2.30
Folate-targeted chemotherapy. Adv Drug Deliv Rev (2004) 2.04
Targeting and inhibition of cell growth by an engineered dendritic nanodevice. J Med Chem (2005) 1.80
Dendritic polymer macromolecular carriers for drug delivery. Curr Opin Chem Biol (2002) 1.77
HPLC analysis of PAMAM dendrimer based multifunctional devices. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.07
Endogenous thymidine and hypoxanthine are a source of error in evaluating methotrexate cytotoxicity by clonogenic assays using undialyzed fetal bovine serum. Int J Cell Cloning (1986) 0.90
Capillary electrophoresis of poly(amidoamine) dendrimers: from simple derivatives to complex multifunctional medical nanodevices. Mol Pharm (2005) 0.87
Identification of a reduced folate/methotrexate carrier in human KB-cells expressing high levels of membrane associated folate binding protein. Adv Exp Med Biol (1993) 0.83
Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res (2005) 4.71
The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform. Chem Biol (2007) 3.36
Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability. Bioconjug Chem (2006) 2.87
Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport. Bioconjug Chem (2004) 2.66
Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face? Acc Chem Res (2007) 2.34
Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy. J Med Chem (2005) 2.32
Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor. Pharm Res (2002) 2.30
PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. Biomacromolecules (2006) 2.17
Light echoes from ancient supernovae in the Large Magellanic Cloud. Nature (2005) 2.07
Synthesis and functional evaluation of DNA-assembled polyamidoamine dendrimer clusters for cancer cell-specific targeting. Chem Biol (2005) 2.05
Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex. Adv Drug Deliv Rev (2005) 1.97
Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers. Nano Lett (2008) 1.96
Protein modification, bioconjugation, and disulfide bridging using bromomaleimides. J Am Chem Soc (2010) 1.89
Targeting and inhibition of cell growth by an engineered dendritic nanodevice. J Med Chem (2005) 1.80
Dendritic polymer macromolecular carriers for drug delivery. Curr Opin Chem Biol (2002) 1.77
Applications of nanotechnology for immunology. Nat Rev Immunol (2013) 1.65
Lipid bilayer disruption by polycationic polymers: the roles of size and chemical functional group. Langmuir (2005) 1.56
Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging. Small (2007) 1.45
Early outcomes from three prospective trials of image-guided proton therapy for prostate cancer. Int J Radiat Oncol Biol Phys (2010) 1.44
Direct observation of lipid bilayer disruption by poly(amidoamine) dendrimers. Chem Phys Lipids (2004) 1.42
Bromomaleimides: new reagents for the selective and reversible modification of cysteine. Chem Commun (Camb) (2009) 1.40
Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis. Chem Commun (Camb) (2011) 1.38
Pre-event smallpox vaccination and postevent exposure and disease: a report of the Joint Task Force on Smallpox Vaccination for Allergists. Ann Allergy Asthma Immunol (2005) 1.38
HER2 specific tumor targeting with dendrimer conjugated anti-HER2 mAb. Bioconjug Chem (2006) 1.36
In situ maleimide bridging of disulfides and a new approach to protein PEGylation. Bioconjug Chem (2011) 1.33
Dendrimer-epidermal growth factor conjugate displays superagonist activity. Biomacromolecules (2008) 1.31
A quantitative assessment of nanoparticle-ligand distributions: implications for targeted drug and imaging delivery in dendrimer conjugates. ACS Nano (2010) 1.29
Hematopoietic stem cell origin of adipocytes. Exp Hematol (2009) 1.28
Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement. Int J Nanomedicine (2008) 1.28
Mucosal immunization with a novel nanoemulsion-based recombinant anthrax protective antigen vaccine protects against Bacillus anthracis spore challenge. Infect Immun (2007) 1.27
Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes. J Phys Chem B (2009) 1.27
Synthesis and in vitro testing of J591 antibody-dendrimer conjugates for targeted prostate cancer therapy. Bioconjug Chem (2004) 1.24
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers. ACS Nano (2008) 1.22
The role of apoptosis in thyroid autoimmunity. Thyroid (2007) 1.20
Pre-clinical evaluation of a novel nanoemulsion-based hepatitis B mucosal vaccine. PLoS One (2008) 1.20
Synthesis, characterization, and intracellular uptake of carboxyl-terminated poly(amidoamine) dendrimer-stabilized iron oxide nanoparticles. Phys Chem Chem Phys (2007) 1.20
Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates. AIDS Res Hum Retroviruses (2008) 1.18
Development of immune response that protects mice from viral pneumonitis after a single intranasal immunization with influenza A virus and nanoemulsion. Vaccine (2003) 1.17
Real-time biomolecular binding detection using a sensitive photonic crystal biosensor. Anal Chem (2010) 1.17
Bromopyridazinedione-mediated protein and peptide bioconjugation. Chem Commun (Camb) (2011) 1.15
Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas. Cancer Res (2002) 1.14
Current dendrimer applications in cancer diagnosis and therapy. Curr Top Med Chem (2008) 1.14
Sensitive molecular binding assay using a photonic crystal structure in total internal reflection. Opt Express (2008) 1.14
Silver/dendrimer nanocomposites as biomarkers: fabrication, characterization, in vitro toxicity, and intracellular detection. Nano Lett (2005) 1.13
In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles. Biomacromolecules (2004) 1.13
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp. J Biol Chem (2003) 1.12
A function for the psi subunit in loading the Escherichia coli DNA polymerase sliding clamp. J Biol Chem (2007) 1.12
Two-photon fluorescence correlation spectroscopy through a dual-clad optical fiber. Opt Express (2008) 1.12
Isolation and characterization of dendrimers with precise numbers of functional groups. Chemistry (2010) 1.11
Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: II. Uncoupling the beta and DNA binding activities of the gamma complex. J Biol Chem (2003) 1.10
Bromomaleimide-linked bioconjugates are cleavable in mammalian cells. Chembiochem (2011) 1.09
HPLC analysis of PAMAM dendrimer based multifunctional devices. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.07
Induction of Th17 cellular immunity with a novel nanoemulsion adjuvant. Crit Rev Immunol (2010) 1.07
Synthetic PAMAM-RGD conjugates target and bind to odontoblast-like MDPC 23 cells and the predentin in tooth organ cultures. Bioconjug Chem (2007) 1.06
The role of ganglioside GM1 in cellular internalization mechanisms of poly(amidoamine) dendrimers. Bioconjug Chem (2009) 1.05
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate. Chem Commun (Camb) (2010) 1.04
Erectile function, incontinence, and other quality of life outcomes following proton therapy for prostate cancer in men 60 years old and younger. Cancer (2012) 1.04
A novel, killed-virus nasal vaccinia virus vaccine. Clin Vaccine Immunol (2007) 1.03
Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis. Arthritis Rheum (2011) 1.03
Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells. Biomacromolecules (2007) 1.03
Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations. Biomacromolecules (2009) 1.03
Poly(amidoamine) dendrimers on lipid bilayers I: Free energy and conformation of binding. J Phys Chem B (2008) 1.02
In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry. Opt Commun (2008) 1.02
A novel inactivated intranasal respiratory syncytial virus vaccine promotes viral clearance without Th2 associated vaccine-enhanced disease. PLoS One (2011) 1.02
Quantitative two-photon flow cytometry--in vitro and in vivo. J Biomed Opt (2008) 1.01
Quantitative analysis of generation and branch defects in G5 poly(amidoamine) dendrimer. Polymer (Guildf) (2013) 1.00
The implications of stochastic synthesis for the conjugation of functional groups to nanoparticles. Bioconjug Chem (2008) 1.00
Understanding specific and nonspecific toxicities: a requirement for the development of dendrimer-based pharmaceuticals. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.00
Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'. Sci Rep (2013) 0.99
Efficacy, immunogenicity and stability of a novel intranasal nanoemulsion-adjuvanted influenza vaccine in a murine model. Hum Vaccin (2010) 0.98
The fungicidal activity of novel nanoemulsion (X8W60PC) against clinically important yeast and filamentous fungi. Mycopathologia (2002) 0.98
Best practices for purification and characterization of PAMAM dendrimer. Macromolecules (2012) 0.98
Polymeric dibromomaleimides as extremely efficient disulfide bridging bioconjugation and pegylation agents. J Am Chem Soc (2012) 0.98
Multifunctional dendrimer-modified multiwalled carbon nanotubes: synthesis, characterization, and in vitro cancer cell targeting and imaging. Biomacromolecules (2009) 0.97
Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates. Anticancer Drugs (2008) 0.97
Molecular dynamics studies of the size, shape, and internal structure of 0% and 90% acetylated fifth-generation polyamidoamine dendrimers in water and methanol. J Phys Chem B (2006) 0.97
HPLC separation of different generations of poly(amidoamine) dendrimers modified with various terminal groups. Anal Chem (2005) 0.96
A unique combination of inflammatory cytokines enhances apoptosis of thyroid follicular cells and transforms nondestructive to destructive thyroiditis in experimental autoimmune thyroiditis. J Immunol (2002) 0.96
IFNgamma sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by upregulating Bak expression. Oncogene (2004) 0.95
Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery. Bioorg Med Chem Lett (2010) 0.94
Comparative effectiveness study of patient-reported outcomes after proton therapy or intensity-modulated radiotherapy for prostate cancer. Cancer (2013) 0.94
Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cell trafficking. Eur J Immunol (2012) 0.94
Synthesis, characterization and stability of a luteinizing hormone-releasing hormone (LHRH)-functionalized poly(amidoamine) dendrimer conjugate. J Biomater Sci Polym Ed (2008) 0.94
HER2 specific delivery of methotrexate by dendrimer conjugated anti-HER2 mAb. Nanotechnology (2008) 0.94
Detection and analysis of tumor fluorescence using a two-photon optical fiber probe. Biophys J (2004) 0.93
Copper-free click conjugation of methotrexate to a PAMAM dendrimer platform. Tetrahedron Lett (2011) 0.93
Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging. Phys Med Biol (2009) 0.93
HPLC analysis of functionalized poly(amidoamine) dendrimers and the interaction between a folate-dendrimer conjugate and folate binding protein. Analyst (2006) 0.92
Topical nanoemulsion therapy reduces bacterial wound infection and inflammation after burn injury. Surgery (2010) 0.92
Dendrimer-based BH3 conjugate that targets human carcinoma cells. Biomacromolecules (2007) 0.92
Efficacy assessment of Aphidius colemani (Hymenoptera: Braconidae) for suppression of Aphis gossypii (Homoptera: Aphididae) in greenhouse-grown chrysanthemum. J Econ Entomol (2006) 0.92
Targeting the efficacy of a dendrimer-based nanotherapeutic in heterogeneous xenograft tumors in vivo. Anticancer Drugs (2010) 0.91
Fiber-optic multiphoton flow cytometry in whole blood and in vivo. J Biomed Opt (2010) 0.91
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. Eur J Med Chem (2011) 0.91
The synthesis of a c(RGDyK) targeted SN38 prodrug with an indolequinone structure for bioreductive drug release. Org Lett (2010) 0.91
Death ligand tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis. Endocrinology (2005) 0.91
Intranasal immunization of ferrets with commercial trivalent influenza vaccines formulated in a nanoemulsion-based adjuvant. Clin Vaccine Immunol (2011) 0.91
The mechanism of polyplex internalization into cells: testing the GM1/caveolin-1 lipid raft mediated endocytosis pathway. Mol Pharm (2010) 0.91
Photochemical release of methotrexate from folate receptor-targeting PAMAM dendrimer nanoconjugate. Photochem Photobiol Sci (2012) 0.91