The RET1 gene of yeast encodes the second-largest subunit of RNA polymerase III. Structural analysis of the wild-type and ret1-1 mutant alleles.

PubWeight™: 1.31‹?› | Rank: Top 10%

🔗 View Article (PMID 2005101)

Published in J Biol Chem on March 25, 1991

Authors

P James1, S Whelen, B D Hall

Author Affiliations

1: Department of Genetics, University of Washington, Seattle 98195.

Articles citing this

Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III. Mol Cell Biol (1994) 1.94

Orientation and topography of RNA polymerase III in transcription complexes. Mol Cell Biol (1993) 1.84

Transcriptional termination signals for RNA polymerase II in fission yeast. EMBO J (1997) 1.72

Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev (1993) 1.71

Comparison of the RNA polymerase III transcription machinery in Schizosaccharomyces pombe, Saccharomyces cerevisiae and human. Nucleic Acids Res (2001) 1.69

Structural perspective on mutations affecting the function of multisubunit RNA polymerases. Microbiol Mol Biol Rev (2006) 1.51

A gene encoding a putative tyrosine phosphatase suppresses lethality of an N-end rule-dependent mutant. Proc Natl Acad Sci U S A (1992) 1.48

Transcription termination by RNA polymerase III: uncoupling of polymerase release from termination signal recognition. Mol Cell Biol (1992) 1.44

Three-dimensional model of yeast RNA polymerase I determined by electron microscopy of two-dimensional crystals. EMBO J (1993) 1.30

The RNA polymerase III terminator used by a B1-Alu element can modulate 3' processing of the intermediate RNA product. Mol Cell Biol (1992) 1.18

RPC53 encodes a subunit of Saccharomyces cerevisiae RNA polymerase C (III) whose inactivation leads to a predominantly G1 arrest. Mol Cell Biol (1992) 1.15

RPC82 encodes the highly conserved, third-largest subunit of RNA polymerase C (III) from Saccharomyces cerevisiae. Mol Cell Biol (1992) 1.11

Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. Mol Cell Biol (1993) 1.10

Termination-altering mutations in the second-largest subunit of yeast RNA polymerase III. Mol Cell Biol (1995) 1.09

C25, an essential RNA polymerase III subunit related to the RNA polymerase II subunit RPB7. Mol Cell Biol (1994) 1.07

Transcription termination by the eukaryotic RNA polymerase III. Biochim Biophys Acta (2012) 1.04

Gene dosage as a possible major determinant for equal expression levels of genes encoding RNA polymerase subunits in the hypotrichous ciliate Euplotes octocarinatus. Nucleic Acids Res (1992) 1.02

Role of a small RNA pol II subunit in TATA to transcription start site spacing. Nucleic Acids Res (1994) 0.99

RNA polymerase III defects suppress a conditional-lethal poly(A) polymerase mutation in Saccharomyces cerevisiae. Genetics (1996) 0.96

Localization of yeast RNA polymerase I core subunits by immunoelectron microscopy. EMBO J (1996) 0.92

Point mutations in the Rpb9-homologous domain of Rpc11 that impair transcription termination by RNA polymerase III. Nucleic Acids Res (2011) 0.92

A unique nucleosome arrangement, maintained actively by chromatin remodelers facilitates transcription of yeast tRNA genes. BMC Genomics (2013) 0.91

The yeast alpha 2 protein can repress transcription by RNA polymerases I and II but not III. Mol Cell Biol (1993) 0.91

TGA cysteine codons and intron sequences in conserved and nonconserved positions are found in macronuclear RNA polymerase genes of Euplotes octocarinatus. Nucleic Acids Res (1992) 0.89

In vitro analysis of elongation and termination by mutant RNA polymerases with altered termination behavior. Mol Cell Biol (1996) 0.88

Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia. Mol Genet Genomics (2010) 0.86

A methods review on use of nonsense suppression to study 3' end formation and other aspects of tRNA biogenesis. Gene (2014) 0.80

RNA polymerase II mutations conferring defects in poly(A) site cleavage and termination in Saccharomyces cerevisiae. G3 (Bethesda) (2013) 0.79

Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo. PLoS Genet (2016) 0.75

Articles by these authors

Codon selection in yeast. J Biol Chem (1982) 19.13

Sequence of the gene for iso-1-cytochrome c in Saccharomyces cerevisiae. Cell (1979) 10.86

Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o. Proc Natl Acad Sci U S A (1977) 10.64

The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase. J Biol Chem (1982) 7.03

Deletion mapping of sequences essential for in vivo transcription of the iso-1-cytochrome c gene. Proc Natl Acad Sci U S A (1981) 6.26

The sequence of the DNAs coding for the mating-type loci of Saccharomyces cerevisiae. Cell (1981) 5.23

A position effect in the control of transcription at yeast mating type loci. Nature (1981) 5.23

Phylogenetic relationships among ascomycetes: evidence from an RNA polymerse II subunit. Mol Biol Evol (1999) 4.83

Mutation of a heterothallic strain to homothallism. Genetics (1975) 4.09

Macromolecule synthesis and breakdown in relation to sporulation and meiosis in yeast. J Bacteriol (1974) 4.07

Transcriptional regulation of the yeast cytochrome c gene. Proc Natl Acad Sci U S A (1979) 3.85

Synthesis and assembly of hepatitis B virus surface antigen particles in yeast. Nature (1982) 3.82

Isolation and sequence of the gene for iso-2-cytochrome c in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1980) 3.62

Identification and isolation of the yeast cytochrome c gene. Cell (1978) 3.39

CHARGE association: an update and review for the primary pediatrician. Clin Pediatr (Phila) (1998) 3.33

Identification of the yeast DNA sequences that correspond to specific tyrosine-inserting nonsense suppressor loci. J Mol Biol (1979) 3.29

Mutations of the yeast SUP4 tRNATyr locus: transcription of the mutant genes in vitro. Cell (1980) 3.24

Isolation and characterization of non-defective transducing elements of bacteriophage phi-80. Virology (1967) 3.15

In vitro mutation analysis of the mating-type locus in yeast. Cell (1981) 3.09

Choanal atresia and associated multiple anomalies. J Pediatr (1979) 2.98

Older paternal age and fresh gene mutation: data on additional disorders. J Pediatr (1975) 2.97

Effects of tRNATyr point mutations on the binding of yeast RNA polymerase III transcription factor C. J Biol Chem (1986) 2.55

The amniotic band disruption complex: timing of amniotic rupture and variable spectra of consequent defects. J Pediatr (1979) 2.46

Expression of a human gene for interferon in yeast. Nature (1981) 2.46

Transcription in yeast: separation and properties of multiple FNA polymerases. Proc Natl Acad Sci U S A (1972) 2.45

Cloning of the yeast tyrosine transfer RNA genes in bacteriophage lambda. J Mol Biol (1979) 2.44

Mating type and sporulation in yeast. I. Mutations which alter mating-type control over sporulation. Genetics (1975) 2.41

Isolation of a gene from Drosophila by complementation in yeast. Nature (1981) 2.30

The primary structure of the alcohol dehydrogenase gene from the fission yeast Schizosaccharomyces pombe. J Biol Chem (1983) 2.29

Incidence of fibrocystic disease in Wessex. J Med Genet (1968) 2.22

Transcription initiation of eucaryotic transfer RNA genes. Cell (1982) 2.18

THE OCCURRENCE OF NATURAL DNA-RNA COMPLEXES IN E. COLI INFECTED WITH T2. Proc Natl Acad Sci U S A (1961) 2.12

Yeast cytochrome c messenger RNA. In vitro translation and specific immunoprecipitation of the CYC1 gene product. J Biol Chem (1976) 2.07

Mutations at the yeast SUP4 tRNATyr locus: DNA sequence changes in mutants lacking suppressor activity. Cell (1980) 2.04

Isolation of the structural gene for alcohol dehydrogenase by genetic complementation in yeast. Nature (1980) 2.03

A new syndrome with hypotonia, obesity, mental deficiency, and facial, oral, ocular, and limb anomalies. J Pediatr (1973) 1.98

An in vitro RNA polymerase III system from S. cerevisiae: effects of deletions and point mutations upon SUP4 gene transcription. Nucleic Acids Res (1982) 1.93

The promoter sequence of a yeast tRNAtyr gene. Cell (1983) 1.91

Only one of two closely related yeast suppressor tRNA genes contains an intervening sequence. Nature (1981) 1.87

Effects of alterations in the 3' flanking sequence on in vivo and in vitro expression of the yeast SUP4-o tRNATyr gene. EMBO J (1985) 1.87

Penetrance and variability in neurofibromatosis: a genetic study of 60 families. Birth Defects Orig Artic Ser (1979) 1.85

Femoral hypoplasia--unusual facies syndrome. J Pediatr (1975) 1.84

Xylose isomerase from Escherichia coli. Characterization of the protein and the structural gene. J Biol Chem (1984) 1.82

The OEIS complex (omphalocele, exstrophy, imperforate anus, spinal defects). Birth Defects Orig Artic Ser (1978) 1.79

Meier-Gorlin syndrome: report of eight additional cases and review. Am J Med Genet (2001) 1.76

The Marfan syndrome locus: confirmation of assignment to chromosome 15 and identification of tightly linked markers at 15q15-q21.3. Genomics (1991) 1.75

Costello syndrome: phenotype, natural history, differential diagnosis, and possible cause. J Pediatr (1998) 1.74

Structural features of yeast tRNA genes which affect transcription factor binding. EMBO J (1984) 1.73

Type of mutation in the neurofibromatosis type 2 gene (NF2) frequently determines severity of disease. Am J Hum Genet (1996) 1.70

Physical analysis of the CYC1-sup4 interval in Saccharomyces cerevisiae. Mol Cell Biol (1981) 1.68

Genetic analysis of the processing of a spliced tRNA. EMBO J (1982) 1.67

Structure of the Schizosaccharomyces pombe cytochrome c gene. Mol Cell Biol (1982) 1.58

Physical analysis of mating-type loci in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol (1981) 1.58

Transforming activity in single-stranded DNA from Bacillus subtilis. J Mol Biol (1968) 1.57

Prader-Willi syndrome. A resumé of 32 cases including an instance of affected first cousins, one of whom is of normal stature and intelligence. J Pediatr (1972) 1.55

Mating type and sporulation in yeast. II. Meiosis, recombination, and radiation sensitivity in an alpha-alpha diploid with altered sporulation control. Genetics (1975) 1.54

Gene size differentially affects the binding of yeast transcription factor tau to two intragenic regions. Proc Natl Acad Sci U S A (1987) 1.53

Prenatal genetic diagnosis in 3000 amniocenteses. N Engl J Med (1979) 1.50

Fibroblast growth factor receptor 2 mutations in Beare-Stevenson cutis gyrata syndrome. Nat Genet (1996) 1.49

Molecular characterisation of the tyrosine tRNA genes of yeast. Nature (1977) 1.44

Level of tryptophan messenger RNA in Escherichia coli. J Mol Biol (1968) 1.43

The origin of red algae: implications for plastid evolution. Proc Natl Acad Sci U S A (1997) 1.42

Transcription in yeast: alpha-amanitin sensitivity and other properties which distinguish between RNA polymerases I and III. Proc Natl Acad Sci U S A (1976) 1.42

Importance of the forest canopy to fluxes of methyl mercury and total mercury to boreal ecosystems. Environ Sci Technol (2001) 1.41

Macrocephaly-cutis marmorata telangiectatica congenita: a distinct disorder with developmental delay and connective tissue abnormalities. Am J Med Genet (1997) 1.38

Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination. Hum Mol Genet (2001) 1.38

Confirmation of the Cohen syndrome. J Pediatr (1978) 1.35

Expression of the Escherichia coli xylose isomerase gene in Saccharomyces cerevisiae. Appl Environ Microbiol (1987) 1.35

Hypochondroplasia: clinical and radiological aspects in 39 cases. Radiology (1979) 1.34

The center-satellite system for the wide-scale distribution of genetic counseling services. Am J Hum Genet (1975) 1.33

Antisense suppression of tomato endo-1,4-beta-glucanase Cel2 mRNA accumulation increases the force required to break fruit abscission zones but does not affect fruit softening. Plant Mol Biol (1999) 1.31

Tetraploidy in a liveborn infant. J Med Genet (1976) 1.31

A yeast mutant defective in the processing of 27S r-RNA precursor. Mol Gen Genet (1976) 1.30

Mutations at the Saccharomyces cerevisiae SUP4 tRNA(Tyr) locus: isolation, genetic fine-structure mapping, and correlation with physical structure. Mol Cell Biol (1982) 1.29

TAP1, a yeast gene that activates the expression of a tRNA gene with a defective internal promoter. Mol Cell Biol (1993) 1.27

DNA sequence elements required for transcription initiation of the Schizosaccharomyces pombe ADH gene in Saccharomyces cerevisiae. Mol Gen Genet (1990) 1.25

Etiologic factors in the amniotic band syndrome: a study of 24 patients. Birth Defects Orig Artic Ser (1977) 1.25

Aglossia-adactylia. Birth Defects Orig Artic Ser (1971) 1.23

Do some patients with Seckel syndrome have hematological problems and/or chromosome breakage? Am J Med Genet (1987) 1.23

Evolutionary complementation for polymerase II CTD function. Yeast (2000) 1.22

Purines are required at the 5' ends of newly initiated RNAs for optimal RNA polymerase III gene expression. Mol Cell Biol (1996) 1.21

Campomelic dysplasia. Further elucidation of a distinct entity. Am J Dis Child (1980) 1.20

The Coffin-Siris syndrome: five new cases including two siblings. Am J Dis Child (1978) 1.19

Thumb polydactyly as a part of the range of genetic expression for thenar hypoplasia. Clin Pediatr (Phila) (1987) 1.18

Langer-Giedion syndrome. Birth Defects Orig Artic Ser (1974) 1.17

Long-branch attraction and the rDNA model of early eukaryotic evolution. Mol Biol Evol (1999) 1.16

Nucleotide sequence of the GDH gene coding for the NADP-specific glutamate dehydrogenase of Saccharomyces cerevisiae. Gene (1985) 1.15

Brief clinical report: a new syndrome of hemangiomatous branchial clefts, lip pseudoclefts, and unusual facial appearance. Am J Med Genet (1983) 1.13

Alpha-thalassemia/mental retardation syndrome often confused with other disorders. Am J Med Genet (1992) 1.12

Duplication (partial trisomy) of the distal long arm of chromosome 17: a new clinically recognizable chromosome disorder. Birth Defects Orig Artic Ser (1978) 1.12

Structure of the yeast TAP1 protein: dependence of transcription activation on the DNA context of the target gene. Mol Cell Biol (1993) 1.12

Syndromes and situations associated with congenital clavicular hypoplasia or agenesis. Prog Clin Biol Res (1982) 1.12

A pattern of craniofacial and limb defects secondary to aberrant tissue bands. J Pediatr (1974) 1.11

Mental retardation and multiple congenital anomalies of unknown etiology: frequency of occurrence in similarly affected sibs of the proband. Birth Defects Orig Artic Ser (1978) 1.11

Familial congenital bowing with short bones. Radiology (1979) 1.10

Albinism and agenesis of the corpus callosum with profound developmental delay: Vici syndrome, evidence for autosomal recessive inheritance. Am J Med Genet (1999) 1.10

Termination-altering mutations in the second-largest subunit of yeast RNA polymerase III. Mol Cell Biol (1995) 1.09