Published in Eur J Hum Genet on January 06, 2010
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Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer. Cancer Cell (2008) 3.01
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Profiling of copy number variations (CNVs) in healthy individuals from three ethnic groups using a human genome 32 K BAC-clone-based array. Hum Mutat (2008) 1.45
Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients. Breast Cancer Res Treat (2006) 1.40
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines. Lab Invest (2008) 1.35
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No common denominator for breast cancer lymph node metastasis. Br J Cancer (2005) 1.20
Chromosome 22 array-CGH profiling of breast cancer delimited minimal common regions of genomic imbalances and revealed frequent intra-tumoral genetic heterogeneity. Int J Oncol (2006) 1.09
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Characterization of novel and complex genomic aberrations in glioblastoma using a 32K BAC array. Neuro Oncol (2009) 1.02
Co-amplification of 8p12 and 11q13 in breast cancers is not the result of a single genomic event. Genes Chromosomes Cancer (2007) 0.96
Omics-based profiling of carcinoma of the breast and matched regional lymph node metastasis. Proteomics (2008) 0.95
Gene arrays for diagnosis, prognosis and treatment of breast cancer metastasis. Clin Exp Metastasis (2007) 0.94
Evidence for limited molecular genetic heterogeneity as defined by allelotyping and clonal analysis in nine metastatic breast carcinomas. Cancer Res (1993) 0.92
A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interaction. Oncogene (2004) 0.88
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Genetic heterogeneity by comparative genomic hybridization in BRCAx breast cancers. Cancer Genet Cytogenet (2008) 0.86
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Caloric restriction delays disease onset and mortality in rhesus monkeys. Science (2009) 9.84
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A promoter-level mammalian expression atlas. Nature (2014) 6.25
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Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature (2012) 5.00
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Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection. J Exp Med (2004) 3.62
Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression. J Immunol (2007) 3.59
Predicting genetic predisposition in humans: the promise of whole-genome markers. Nat Rev Genet (2010) 3.59
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A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One (2008) 3.25
Evaluation of a portable device to measure daily energy expenditure in free-living adults. Am J Clin Nutr (2007) 3.18
Modernising medical careers, medical training application service, and the postgraduate medical education and training board: time for the emperors to don their clothes. Lancet (2007) 3.12
Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. Genetics (2005) 3.10
LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies. Nat Med (2004) 3.00
Detection of gene x gene interactions in genome-wide association studies of human population data. Hum Hered (2007) 2.97
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion. Endocrinology (2007) 2.95
Towards sound epistemological foundations of statistical methods for high-dimensional biology. Nat Genet (2004) 2.72
Ten putative contributors to the obesity epidemic. Crit Rev Food Sci Nutr (2009) 2.71
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus. J Exp Med (2008) 2.59
Dominance of CD8 responses specific for epitopes bound by a single major histocompatibility complex class I molecule during the acute phase of viral infection. J Virol (2002) 2.50
Mortality, health outcomes, and body mass index in the overweight range: a science advisory from the American Heart Association. Circulation (2009) 2.49
Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge. J Virol (2009) 2.38
Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal model analysis. Arch Gen Psychiatry (2005) 2.35
Molecular recognition by LARGE is essential for expression of functional dystroglycan. Cell (2004) 2.33
Comparison of autologous and allogeneic hematopoietic stem cell transplantation for follicular lymphoma. Blood (2003) 2.31
Somatic mosaicism for copy number variation in differentiated human tissues. Hum Mutat (2008) 2.30
Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods. PLoS One (2009) 2.21
Botulinum toxin type A (BOTOX) for the prophylactic treatment of chronic daily headache: a randomized, double-blind, placebo-controlled trial. Headache (2005) 2.16
Age-related somatic structural changes in the nuclear genome of human blood cells. Am J Hum Genet (2012) 2.15
Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239. J Virol (2003) 2.14
Achieving evolvable Web-database bioscience applications using the EAV/CR framework: recent advances. J Am Med Inform Assoc (2003) 2.13
Functional analysis of transcription factor binding sites in human promoters. Genome Biol (2012) 2.12
Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality. Nat Struct Mol Biol (2013) 2.11
Bayesian model choice and search strategies for mapping interacting quantitative trait Loci. Genetics (2003) 2.05
Is percentage body fat differentially related to body mass index in Hispanic Americans, African Americans, and European Americans? Am J Clin Nutr (2003) 2.01
Attenuation of sarcopenia by dietary restriction in rhesus monkeys. J Gerontol A Biol Sci Med Sci (2008) 2.00
Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc Natl Acad Sci U S A (2002) 1.97
Sources of variation in Affymetrix microarray experiments. BMC Bioinformatics (2005) 1.94
Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr (2011) 1.94
Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles. Hum Hered (2008) 1.92
DNA sequence and analysis of human chromosome 8. Nature (2006) 1.91
Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis. PLoS Genet (2009) 1.91
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
Waist Circumference and Cardiometabolic Risk: a Consensus Statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, the Obesity Society; the American Society for Nutrition; and the American Diabetes Association. Obesity (Silver Spring) (2007) 1.87
Visceral adipose tissue modulates mammalian longevity. Aging Cell (2008) 1.87
Association of African genetic admixture with resting metabolic rate and obesity among women. Obes Res (2003) 1.86
Canaries in the coal mine: a cross-species analysis of the plurality of obesity epidemics. Proc Biol Sci (2010) 1.86
"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits. Am J Hum Genet (2003) 1.82
Body-size dependence of resting energy expenditure can be attributed to nonenergetic homogeneity of fat-free mass. Am J Physiol Endocrinol Metab (2002) 1.82
Salvage second hematopoietic cell transplantation in myeloma. Biol Blood Marrow Transplant (2013) 1.80
Self-report-based estimates of energy intake offer an inadequate basis for scientific conclusions. Am J Clin Nutr (2013) 1.79
Exon array CGH: detection of copy-number changes at the resolution of individual exons in the human genome. Am J Hum Genet (2005) 1.78
Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication. J Virol (2007) 1.78
Vaccine-induced CD8+ T cells control AIDS virus replication. Nature (2012) 1.78
Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell (2013) 1.71
Neuro-ophthalmology of invasive fungal sinusitis: 14 consecutive patients and a review of the literature. Clin Experiment Ophthalmol (2013) 1.70
Using the Edmonton obesity staging system to predict mortality in a population-representative cohort of people with overweight and obesity. CMAJ (2011) 1.70
A full-coverage, high-resolution human chromosome 22 genomic microarray for clinical and research applications. Hum Mol Genet (2002) 1.69
Association between fitness and changes in body composition and muscle strength. J Am Geriatr Soc (2010) 1.68
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Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction. FASEB J (2003) 1.66
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CD86+ or HLA-G+ can be transferred via trogocytosis from myeloma cells to T cells and are associated with poor prognosis. Blood (2012) 1.65
AlzPharm: integration of neurodegeneration data using RDF. BMC Bioinformatics (2007) 1.65
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. J Mol Med (Berl) (2013) 1.64
Long-term changes in adiposity and glycemic control are associated with past adenovirus infection. Diabetes Care (2012) 1.63