Loic Le Marchand

Author PubWeight™ 288.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007 29.23
2 Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet 2007 14.37
3 Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2007 10.81
4 Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 2013 8.24
5 Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2008 7.65
6 Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 2008 6.22
7 Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet 2009 6.04
8 Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet 2013 5.58
9 Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst 2010 4.54
10 Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet 2013 4.35
11 Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 2013 3.81
12 Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet 2009 3.76
13 Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet 2012 3.69
14 Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet 2012 3.68
15 Circulating 25-hydroxyvitamin D and risk of pancreatic cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Am J Epidemiol 2010 3.51
16 A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res 2007 3.08
17 Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet 2011 3.07
18 The landscape of recombination in African Americans. Nature 2011 3.06
19 Identification of Lynch syndrome among patients with colorectal cancer. JAMA 2012 2.77
20 Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Hum Mol Genet 2011 2.72
21 Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet 2011 2.70
22 Generalizability of associations from prostate cancer genome-wide association studies in multiple populations. Cancer Epidemiol Biomarkers Prev 2009 2.67
23 FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation. Hum Mol Genet 2009 2.62
24 Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology 2012 2.57
25 Risks of Lynch syndrome cancers for MSH6 mutation carriers. J Natl Cancer Inst 2009 2.56
26 Genome-wide association study identifies new prostate cancer susceptibility loci. Hum Mol Genet 2011 2.51
27 Fine mapping of the association with obesity at the FTO locus in African-derived populations. Hum Mol Genet 2010 2.48
28 A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet 2012 2.45
29 Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet 2011 2.35
30 Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet 2013 2.24
31 Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study. PLoS Biol 2013 2.08
32 Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res 2007 2.02
33 Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium. PLoS Genet 2010 1.98
34 Genome-wide association study of glioma and meta-analysis. Hum Genet 2012 1.96
35 Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer. PLoS Genet 2012 1.91
36 Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Am J Epidemiol 2010 1.90
37 Association studies of common variants in 10 hypogonadotropic hypogonadism genes with age at menarche. J Clin Endocrinol Metab 2008 1.83
38 A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet 2013 1.82
39 Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Hum Mol Genet 2013 1.78
40 Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status. Cancer Epidemiol Biomarkers Prev 2009 1.72
41 Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network. PLoS Genet 2013 1.70
42 Genetic variation in the HSD17B1 gene and risk of prostate cancer. PLoS Genet 2005 1.67
43 Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study. PLoS One 2012 1.65
44 Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestry. Cancer Res 2011 1.59
45 Association of ESR1 gene tagging SNPs with breast cancer risk. Hum Mol Genet 2009 1.58
46 Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet 2012 1.57
47 Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet 2013 1.57
48 Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium. Hum Mol Genet 2011 1.55
49 Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans. PLoS Genet 2011 1.54
50 Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet 2011 1.47
51 A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. Hum Mol Genet 2012 1.47
52 Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3. PLoS One 2011 1.41
53 Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study. Cancer Epidemiol Biomarkers Prev 2011 1.40
54 Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. Am J Hum Genet 2013 1.39
55 Fine scale mapping of the breast cancer 16q12 locus. Hum Mol Genet 2010 1.39
56 Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. Cancer Epidemiol Biomarkers Prev 2010 1.38
57 Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines. Chem Res Toxicol 2011 1.38
58 Use of weighted reference panels based on empirical estimates of ancestry for capturing untyped variation. Hum Genet 2009 1.37
59 Two estrogen-related variants in CYP19A1 and endometrial cancer risk: a pooled analysis in the Epidemiology of Endometrial Cancer Consortium. Cancer Epidemiol Biomarkers Prev 2009 1.37
60 Dietary and lifestyle correlates of plasma insulin-like growth factor-I (IGF-I) and IGF binding protein-3 (IGFBP-3): the multiethnic cohort. Cancer Epidemiol Biomarkers Prev 2004 1.34
61 Dietary fiber and colorectal cancer risk: the multiethnic cohort study. Cancer Causes Control 2007 1.33
62 Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clin Cancer Res 2010 1.32
63 Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium. Diabetes 2012 1.31
64 Association of selenium, tocopherols, carotenoids, retinol, and 15-isoprostane F(2t) in serum or urine with prostate cancer risk: the multiethnic cohort. Cancer Causes Control 2009 1.31
65 Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev 2009 1.29
66 Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study. Obesity (Silver Spring) 2013 1.28
67 Fine Mapping and Identification of BMI Loci in African Americans. Am J Hum Genet 2013 1.27
68 Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium. Am J Epidemiol 2012 1.27
69 Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry. J Mol Diagn 2011 1.27
70 Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk. Cancer Epidemiol Biomarkers Prev 2012 1.26
71 Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations. Hum Mol Genet 2007 1.24
72 Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev 2009 1.23
73 A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study. PLoS Genet 2013 1.21
74 Analysis of case-control association studies with known risk variants. Bioinformatics 2012 1.20
75 Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23. Hum Mol Genet 2013 1.19
76 Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer. Hum Mol Genet 2011 1.17
77 Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer. Clin Cancer Res 2009 1.17
78 Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples. PLoS Genet 2010 1.14
79 Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort. Cancer Epidemiol Biomarkers Prev 2006 1.14
80 PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3). Carcinogenesis 2009 1.13
81 CYP1A1 T3801 C polymorphism and lung cancer: a pooled analysis of 2451 cases and 3358 controls. Int J Cancer 2003 1.13
82 Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics 2013 1.11
83 A genome-wide association study of breast cancer in women of African ancestry. Hum Genet 2012 1.11
84 Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population. PLoS Genet 2013 1.10
85 Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts. Int J Cancer 2007 1.09
86 Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium. Eur J Cancer 2012 1.07
87 Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry. Cancer Epidemiol Biomarkers Prev 2010 1.07
88 Imputation of coding variants in African Americans: better performance using data from the exome sequencing project. Bioinformatics 2013 1.05
89 Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium. Am J Epidemiol 2012 1.05
90 A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. J Clin Endocrinol Metab 2010 1.04
91 Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases. J Mol Diagn 2010 1.04
92 Urinary phytoestrogen excretion and postmenopausal breast cancer risk: the multiethnic cohort study. Cancer Prev Res (Phila) 2009 1.03
93 Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiol Biomarkers Prev 2010 1.03
94 Germ line variation at 8q24 and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev 2007 1.03
95 The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women. PLoS One 2011 1.03
96 CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions. Biomarkers 2005 1.02
97 Trends of breast cancer incidence and risk factor prevalence over 25 years. Breast Cancer Res Treat 2006 1.01
98 Variation in genetic admixture and population structure among Latinos: the Los Angeles Latino eye study (LALES). BMC Genet 2009 1.01
99 A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium. Hum Mol Genet 2013 1.00
100 Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2. Cancer Epidemiol Biomarkers Prev 2010 0.99
101 SBERIA: set-based gene-environment interaction test for rare and common variants in complex diseases. Genet Epidemiol 2013 0.99
102 A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 2010 0.99
103 Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. Breast Cancer Res 2014 0.99
104 Igf-I genetic variation and breast cancer: the multiethnic cohort. Cancer Epidemiol Biomarkers Prev 2006 0.97
105 Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22. Cancer Res 2010 0.96
106 Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese. PLoS One 2012 0.96
107 Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer 2014 0.96
108 Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. BMC Cancer 2009 0.96
109 Genome-wide search for gene-gene interactions in colorectal cancer. PLoS One 2012 0.96
110 Lifestyle and dietary correlates of plasma insulin-like growth factor binding protein-1 (IGFBP-1), leptin, and C-peptide: the Multiethnic Cohort. Nutr Cancer 2007 0.95
111 Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO). Int J Cancer 2014 0.95
112 Replication of five prostate cancer loci identified in an Asian population--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3). Cancer Epidemiol Biomarkers Prev 2011 0.95
113 A systematic assessment of common genetic variation in CYP11A and risk of breast cancer. Cancer Res 2006 0.94
114 Myeloperoxidase G-463A polymorphism and lung cancer: a HuGE genetic susceptibility to environmental carcinogens pooled analysis. Genet Med 2007 0.94
115 A common prostate cancer risk variant 5' of microseminoprotein-beta (MSMB) is a strong predictor of circulating beta-microseminoprotein (MSP) levels in multiple populations. Cancer Epidemiol Biomarkers Prev 2010 0.94
116 Large-scale fine mapping of the HNF1B locus and prostate cancer risk. Hum Mol Genet 2011 0.94
117 An investigation of mammographic density and gene variants in healthy women. Int J Cancer 2004 0.94
118 Biomonitoring of carcinogenic heterocyclic aromatic amines in hair: a validation study. Chem Res Toxicol 2009 0.93
119 Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22. PLoS One 2012 0.93
120 Genome-wide association study of endometrial cancer in E2C2. Hum Genet 2013 0.93
121 Cigarette smoking and risk of colorectal cancer among Norwegian women. Cancer Causes Control 2009 0.92
122 Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control 2009 0.92
123 The association of tumor microsatellite instability phenotype with family history of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2009 0.91
124 CYP1A1, GSTM1, and GSTT1 polymorphisms, smoking, and lung cancer risk in a pooled analysis among Asian populations. Cancer Epidemiol Biomarkers Prev 2008 0.91
125 Aspirin and NSAID use and lung cancer risk: a pooled analysis in the International Lung Cancer Consortium (ILCCO). Cancer Causes Control 2011 0.89
126 Association of metabolic gene polymorphisms with tobacco consumption in healthy controls. Int J Cancer 2004 0.89
127 Genetic variation in the progesterone receptor gene and risk of endometrial cancer: a haplotype-based approach. Carcinogenesis 2010 0.88
128 Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO). Cancer Causes Control 2010 0.88
129 A genome-wide scan for breast cancer risk haplotypes among African American women. PLoS One 2013 0.87
130 A priori-defined diet quality indexes and risk of type 2 diabetes: the Multiethnic Cohort. Diabetologia 2014 0.85
131 Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study. BMC Med Genet 2013 0.85
132 Genome-wide association study of age at menarche in African-American women. Hum Mol Genet 2013 0.85
133 Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3). Int J Cancer 2013 0.84
134 Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2013 0.84
135 Genetic variants of adiponectin and risk of colorectal cancer. Int J Cancer 2014 0.84
136 Obesity and non-Hodgkin lymphoma survival in an ethnically diverse population: the Multiethnic Cohort study. Cancer Causes Control 2014 0.84
137 Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study. BMC Med Genet 2013 0.84
138 Use of folic acid-containing supplements after a diagnosis of colorectal cancer in the Colon Cancer Family Registry. Cancer Epidemiol Biomarkers Prev 2010 0.82
139 Genetic variations in SMAD7 are associated with colorectal cancer risk in the colon cancer family registry. PLoS One 2013 0.81
140 Plasma carotenoid- and retinol-weighted multi-SNP scores and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev 2013 0.81
141 Ethnic differences in trends and determinants of cigarette smoking in Hawaii. Ethn Dis 2005 0.81
142 Serum coenzyme Q₁₀, α-tocopherol, γ-tocopherol, and C-reactive protein levels and body mass index in adolescent and premenopausal females. J Am Coll Nutr 2014 0.80
143 Validation of a quantitative FFQ for a study of diet and risk of colorectal adenoma among Japanese Brazilians. Public Health Nutr 2012 0.80
144 The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA. Hum Genet 2011 0.79
145 Reliability of KRAS mutation testing in metastatic colorectal cancer patients across five laboratories. BMC Res Notes 2012 0.79
146 Population genetic structure and origins of Native Hawaiians in the multiethnic cohort study. PLoS One 2012 0.79
147 Additive interactions between susceptibility single-nucleotide polymorphisms identified in genome-wide association studies and breast cancer risk factors in the Breast and Prostate Cancer Cohort Consortium. Am J Epidemiol 2014 0.78
148 Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study. Circ Cardiovasc Genet 2014 0.77
149 Atopic allergic conditions and colorectal cancer risk in the Multiethnic Cohort Study. Am J Epidemiol 2015 0.77
150 Corrigendum: Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun 2015 0.76
151 Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer. Genet Epidemiol 2015 0.75
152 Birth size and later central obesity among adolescent girls of Asian, White, and Mixed ethnicities. Hawaii J Med Public Health 2013 0.75
153 Sex Differences in Risk of Smoking- Associated Lung Cancer: Results From a Cohort of 600,000 Norwegians. Am J Epidemiol 2017 0.75
154 Nutritional composition of dishes commonly consumed by Japanese Brazilians in São Paulo, Brazil. Int J Food Sci Nutr 2010 0.75