Published in Endocrinology on January 07, 2010
Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice. PLoS One (2012) 1.50
Reducing plasma membrane sphingomyelin increases insulin sensitivity. Mol Cell Biol (2011) 1.20
Nutrient excess stimulates β-cell neogenesis in zebrafish. Diabetes (2012) 1.04
Pancreatic beta-cells: from generation to regeneration. Semin Cell Dev Biol (2010) 0.97
Regeneration of pancreatic non-β endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin. PLoS One (2012) 0.92
Nutritional programming of pancreatic β-cell plasticity. World J Diabetes (2011) 0.89
α-cell role in β-cell generation and regeneration. Islets (2012) 0.89
Mouse insulin cells expressing an inducible RIPCre transgene are functionally impaired. J Biol Chem (2014) 0.81
Pancreas β cell regeneration and type 1 diabetes (Review). Exp Ther Med (2014) 0.81
Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters. Islets (2016) 0.79
Development and regeneration in the endocrine pancreas. ISRN Endocrinol (2012) 0.79
Obestatin enhances in vitro generation of pancreatic islets through regulation of developmental pathways. PLoS One (2013) 0.78
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature (2004) 16.56
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development (2002) 12.21
Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature (1985) 9.78
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell (2008) 8.57
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A (2000) 8.34
Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev Cell (2007) 4.90
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells. Cell (2009) 4.47
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A (2008) 4.01
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. Diabetes (2000) 3.46
All beta cells contribute equally to islet growth and maintenance. PLoS Biol (2007) 3.19
A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development. Diabetes (1993) 3.01
Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. Cell (1988) 2.99
Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes (2001) 2.95
Gene regulatory factors in pancreatic development. Dev Dyn (2004) 2.69
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev Cell (2007) 2.68
Regulation of pancreatic beta-cell mass. Physiol Rev (2005) 2.66
Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. Mol Cell Biol (2003) 2.64
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest (2003) 2.63
A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol (2006) 2.62
Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis. Mech Dev (2003) 2.58
MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene. J Biol Chem (2002) 2.22
Regulation of the pancreatic pro-endocrine gene neurogenin3. Diabetes (2001) 2.19
The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proc Natl Acad Sci U S A (2004) 2.14
MafB is required for islet beta cell maturation. Proc Natl Acad Sci U S A (2007) 2.13
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A (2009) 2.09
Perspective: Postnatal pancreatic beta cell growth. Endocrinology (2000) 2.08
MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells. Diabetes (2006) 2.01
Specifying pancreatic endocrine cell fates. Mech Dev (2006) 1.84
Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes. Endocrinology (2001) 1.78
Beta-cell proliferation, but not neogenesis, following 60% partial pancreatectomy is impaired in the absence of FoxM1. Diabetes (2008) 1.46
Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells. J Mol Endocrinol (2004) 1.30
Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets. Endocrinology (1997) 1.28
Insulin gene: organisation, expression and regulation. Diabetes Metab (1996) 0.89
Microwave-accelerated fixation and lacZ activity staining of testicular cells in transgenic mice. Anal Biochem (1991) 0.85
Accessing genetic information with high-density DNA arrays. Science (1996) 13.89
Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development (1995) 4.38
Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci (1997) 3.61
The molecular architecture of focal adhesions. Annu Rev Cell Dev Biol (1995) 3.41
Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J Neurosci (2000) 3.40
Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. Cell (1988) 2.99
Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain. Neurosci Lett (2000) 2.22
Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor. J Biol Chem (2000) 2.19
[Number of patients with chronic dyspnea in three German specialist practices]. Pneumologie (2012) 2.08
Laparoscopic sleeve gastrectomy as a weight reduction strategy in obese patients after kidney transplantation. Am J Transplant (2014) 2.02
Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension. Eur Respir J (2004) 2.02
Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol (1994) 1.89
Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes. Endocrinology (2001) 1.78
Treatment of systemic sclerosis with autologous haemopoietic stem cell transplantation. Lancet (1997) 1.76
A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group. J Am Coll Cardiol (2000) 1.73
Orexin receptor antagonism, a new sleep-promoting paradigm: an ascending single-dose study with almorexant. Clin Pharmacol Ther (2010) 1.57
Inhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial. German PPH Study Group. Ann Intern Med (2000) 1.57
XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol Endocrinol (1994) 1.54
Intraparenchymal infusions of 192 IgG-saporin: development of a method for selective and discrete lesioning of cholinergic basal forebrain nuclei. J Neurosci Methods (1999) 1.52
Factors influencing breath condensate volume. Pneumologie (2001) 1.51
Hypertension and a tumor of the glomus jugulare region. Evidence for epinephrine biosynthesis. Am J Hypertens (1993) 1.47
Location and type of mutation in the LIS1 gene do not predict phenotypic severity. Neurology (2007) 1.45
Cell lineage analysis of pancreatic islet development: glucagon and insulin cells arise from catecholaminergic precursors present in the pancreatic duct. Dev Biol (1987) 1.45
Long-term outcome with intravenous iloprost in pulmonary arterial hypertension. Eur Respir J (2009) 1.44
Functional imaging in PNH caused by a new FilaminA mutation. Neurology (2004) 1.43
[Correlation of TEI Index and invasive parameters of rightheart function in PAH]. Pneumologie (2004) 1.38
ARX mutations in X-linked lissencephaly with abnormal genitalia. Neurology (2003) 1.36
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol Dis (2010) 1.35
Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets. Endocrinology (1997) 1.28
Frequency and phenotype of SPG11 and SPG15 in complicated hereditary spastic paraplegia. J Neurol Neurosurg Psychiatry (2009) 1.26
Appearance of catecholamine-synthesizing enzymes during development of rat sympathetic nervous system: possible role of tissue environment. Proc Natl Acad Sci U S A (1979) 1.26
Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic alpha cells. Neuron (1988) 1.24
"Motor circuit" gray matter changes in idiopathic cervical dystonia. Neurology (2003) 1.20
Transcranial color-coded real-time sonography in adults. Stroke (1990) 1.12
Molecular genetic investigations in the CCM1 gene in sporadic cerebral cavernomas. Neurology (2003) 1.12
Hypothalamic gray matter changes in narcoleptic patients. Nat Med (2002) 1.10
Low frequency of BMPR2 mutations in a German cohort of patients with sporadic idiopathic pulmonary arterial hypertension. J Med Genet (2004) 1.08
Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis. Endocrinology (2003) 1.08
Some neurons of the rat central nervous system contain aromatic-L-amino-acid decarboxylase but not monoamines. Science (1983) 1.07
Catecholamine biosynthetic enzymes are expressed in replicating cells of the peripheral but not the central nervous system. Proc Natl Acad Sci U S A (1980) 1.06
Analysis of breast milk to assess exposure to chlorinated contaminants in Kazakstan: high levels of 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in agricultural villages of southern Kazakstan. Environ Health Perspect (1998) 1.04
A filamin A splice mutation resulting in a syndrome of facial dysmorphism, periventricular nodular heterotopia, and severe constipation reminiscent of cerebro-fronto-facial syndrome. J Med Genet (2005) 1.04
Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription. J Biol Chem (1994) 1.03
Somatic mosaicism and variable penetrance in doublecortin-associated migration disorders. Neurology (2003) 1.03
Bosentan therapy for portopulmonary hypertension. Eur Respir J (2005) 1.02
Further clinical and genetic characterization of SPG11: hereditary spastic paraplegia with thin corpus callosum. Neuropediatrics (2006) 1.02
Calcified neurocysticercosis lesions trigger symptomatic inflammation during antiparasitic therapy. AJNR Am J Neuroradiol (2006) 0.99
Different expression of endothelin in the bronchoalveolar lavage in patients with pulmonary diseases. Lung (2002) 0.98
Transformation of catecholaminergic precursors into glucagon (A) cells in mouse embryonic pancreas. Proc Natl Acad Sci U S A (1981) 0.97
Signposts in the assembly of chylomicrons. Front Biosci (2001) 0.97
Increased interleukin-6 in collected drainage blood after total knee arthroplasty: an association with febrile reactions during retransfusion. Acta Orthop Scand (2001) 0.96
Novel truncating and missense mutations of the KCC3 gene associated with Andermann syndrome. Neurology (2006) 0.95
Transcranial color-coded real-time sonography in the evaluation of intracranial neoplasms and arteriovenous malformations. Neurosurgery (1992) 0.95
First experimental and clinical results with transscleral optical coherence tomography. Ophthalmic Surg Lasers (2000) 0.95
Peripheral airway obstruction in primary pulmonary hypertension. Thorax (2002) 0.95
Analysis of breast milk to assess exposure to chlorinated contaminants in Kazakstan: PCBs and organochlorine pesticides in southern Kazakstan. Environ Health Perspect (1997) 0.94
The emergency contraception collaborative prescribing experience in Washington State. J Am Pharm Assoc (Wash) (2001) 0.94
The isolation and characterization of monopyrroles from Serratia marcescens. Biochem Biophys Res Commun (1972) 0.94
Linkage of the brain-skin-gut axis: islet cells originate from dopaminergic precursors. Peptides (1981) 0.94
Aspergillus detection in bronchoscopically acquired material. Significance and interpretation. Mycoses (2001) 0.93
Defective polymorphonuclear leukocyte formyl peptide receptor(s) in juvenile periodontitis. J Clin Invest (1991) 0.93
Compliance in hemodialysis patients: a multivariate regression analysis. Nephron (1993) 0.91
Sorafenib induces sustained molecular remission in FLT3-ITD positive AML with relapse after second allogeneic stem cell transplantation without exacerbation of acute GVHD: a case report. Leuk Res (2010) 0.91
Effects of 8-wk alpha-glucosidase inhibition on metabolic control, C-peptide secretion, hepatic glucose output, and peripheral insulin sensitivity in poorly controlled type II diabetic patients. Diabetes Care (1989) 0.90
Islet injury induces neurotrophin expression in pancreatic cells and reactive gliosis of peri-islet Schwann cells. J Neurobiol (1998) 0.89
Switching from tacrolimus to sirolimus halts the appearance of new sebaceous neoplasms in Muir-Torre syndrome. Am J Transplant (2007) 0.89
Tracking the Response of Burkholderia cepacia G4 5223-PR1 in Aquifer Microcosms. Appl Environ Microbiol (1995) 0.88
Photodynamics of the bacteriochlorophyll-carotenoid system. 1. Bacteriochlorophyll-photosensitized oxygenation of beta-carotene in acetone. Photochem Photobiol (2001) 0.88
Biosynthesis of the 3-acetyl and 13(1)-oxo groups of bacteriochlorophyll a in the facultative aerobic bacterium, Rhodovulum sulfidophilum--the presence of both oxygenase and hydratase pathways for isocyclic ring formation. Eur J Biochem (1998) 0.88
Mobilization of CD34+ hematopoietic cells, colony-forming cells and long-term culture-initiating cells into the peripheral blood of patients with an acute cerebral ischemic insult. Cytotherapy (2008) 0.87
Agenesis of the corpus callosum, abnormal genitalia and intractable epilepsy due to a novel familial mutation in the Aristaless-related homeobox gene. Neuropediatrics (2004) 0.87
Plasmodium falciparum: merozoite surface proteins 1 and 2 are not posttranslationally modified by classical N- or O-glycans. Exp Parasitol (2000) 0.87
Reliability of atlas-derived coordinates in deep brain stimulation. Acta Neurochir (Wien) (2005) 0.87
Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression. Mol Cell Biol (1994) 0.86
Catecholamine-synthesizing enzymes in paraganglia of aged Fischer-344 rats. Immunohistochemistry and fluorescence microscopy. Cell Tissue Res (1984) 0.85
Isolated lissencephaly sequence and double-cortex syndrome in a German family with a novel doublecortin mutation. Neuropediatrics (2000) 0.85
Carp preproinsulin cDNA sequence and evolution of insulin genes. Nucleic Acids Res (1983) 0.84
Molecular mechanisms of neuronal migration disorders, quo vadis? Curr Mol Med (2001) 0.84
Cytosine arabinoside induces ectoderm and inhibits mesoderm expression in human embryonic stem cells during multilineage differentiation. Br J Pharmacol (2011) 0.84
Differential kinetics of primitive hematopoietic cells assayed in vitro and in vivo during serum-free suspension culture of CD34+ blood progenitor cells. Stem Cells (1999) 0.84
Cholinergic neurons of the chick ciliary ganglia express adrenergic traits in vivo and in vitro. J Neurosci (1985) 0.84
Dose-dependent effect of S(+) ketamine on post-ischemic endogenous neurogenesis in rats. Acta Anaesthesiol Scand (2009) 0.84
Preweaning enrichment has no lasting effects on adult hippocampal neurogenesis in four-month-old mice. Genes Brain Behav (2002) 0.84
Clinical spectrum of muscle-eye-brain disease: from the typical presentation to severe autistic features. Acta Myol (2004) 0.83
Pulmonary nocardiosis with cutaneous involvement mimicking a metastasizing lung carcinoma in a patient with chronic myelogenous leukaemia. Eur J Dermatol (2000) 0.83
Inhibition of angiotensin converting enzyme by ramipril in serum and tissue of man. J Hypertens (1991) 0.83
A pharmacokinetic/pharmacodynamic approach to predict total prednisolone concentrations in human plasma. J Pharmacokinet Pharmacodyn (2007) 0.83
Expression of amino acid decarboxylase in proliferating cells of the neural tube and notochord of developing rat embryo. J Neurosci (1983) 0.83
Therapeutic Regulation of Inflammation and Angiogenesis in Cancer, Arthritis, and Asthma, Sixth Annual Midwest Meeting, Chicago, IL, USA, March 16, 1998. Inflamm Res (1999) 0.82
[Retinal damage by perfluorocarbon liquids - a question of specific gravity? Intraocular pressure peaks and shearing forces]. Klin Monbl Augenheilkd (2009) 0.82
Differentiation of prospective mouse pancreatic islet cells during development in vitro and during regeneration. Dev Biol (1987) 0.82
Effects of residual renal function in haemodialysis patients. Int Urol Nephrol (1994) 0.82
Variability of fatty acid content in pumpkin seeds (Cucurbita pepo L.). Z Lebensm Unters Forsch (1996) 0.82
[Accumulation of lipid particles in Bruch's membrane of LDL receptor knockout mice as a model of age-related macular degeneration]. Ophthalmologe (2004) 0.82
Andermann syndrome can be a phenocopy of hereditary motor and sensory neuropathy--report of a discordant sibship with a compound heterozygous mutation of the KCC3 gene. Neuropediatrics (2009) 0.81
Detrimental effect of protracted hyperglycaemia on beta-cell neogenesis in a mouse murine model of diabetes. Diabetologia (2002) 0.81
[Acupuncture in diseases of the locomotor system. Status of research and clinical applications]. Orthopade (2002) 0.81
[Iloprost as inhalational and intravenous long-term treatment of patients with primary pulmonary hypertension. Register of the Berlin Study Group for Pulmonary Hypertension]]. Z Kardiol (2000) 0.81