Published in Acta Crystallogr D Biol Crystallogr on December 21, 2009
The crystal structure of Streptococcus pyogenes uridine phosphorylase reveals a distinct subfamily of nucleoside phosphorylases. Biochemistry (2011) 0.82
A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity. J Struct Biol (2011) 0.78
Expression, purification, crystallization and preliminary X-ray structure analysis of Vibrio cholerae uridine phosphorylase in complex with thymidine. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.77
Active site conformational dynamics in human uridine phosphorylase 1. PLoS One (2010) 0.77
Crystallization and preliminary X-ray study of Vibrio cholerae uridine phosphorylase in complex with 6-methyluracil. Acta Crystallogr F Struct Biol Commun (2013) 0.75
In vivo protein crystallization opens new routes in structural biology. Nat Methods (2012) 2.69
Spatial structure of the dimeric transmembrane domain of the growth factor receptor ErbB2 presumably corresponding to the receptor active state. J Biol Chem (2008) 1.81
Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger. J Biol Chem (2007) 1.56
Human copper-transporting ATPase ATP7B (the Wilson's disease protein): biochemical properties and regulation. J Bioenerg Biomembr (2002) 1.35
Spatial structure and pH-dependent conformational diversity of dimeric transmembrane domain of the receptor tyrosine kinase EphA1. J Biol Chem (2008) 1.33
Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice. J Immunol (2005) 1.22
Efficient UV detection of protein crystals enabled by fluorescence excitation at wavelengths longer than 300 nm. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 1.20
PLATINUM: a web tool for analysis of hydrophobic/hydrophilic organization of biomolecular complexes. Bioinformatics (2009) 1.19
Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis. FEBS J (2011) 1.19
The distinct functional properties of the nucleotide-binding domain of ATP7B, the human copper-transporting ATPase: analysis of the Wilson disease mutations E1064A, H1069Q, R1151H, and C1104F. J Biol Chem (2004) 1.19
Left-handed dimer of EphA2 transmembrane domain: Helix packing diversity among receptor tyrosine kinases. Biophys J (2010) 1.14
Quantitative real-time analysis of nucleolar stress by coherent phase microscopy. J Biomed Opt (2009) 1.12
The first crystal structure of an RNA racemate. Acta Crystallogr D Biol Crystallogr (2006) 1.08
Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy. J Biol Chem (2011) 1.01
The role of the invariant His-1069 in folding and function of the Wilson's disease protein, the human copper-transporting ATPase ATP7B. J Biol Chem (2003) 1.01
Structural insights into the catalytic mechanism of sphingomyelinases D and evolutionary relationship to glycerophosphodiester phosphodiesterases. Biochem Biophys Res Commun (2006) 1.00
Insulin receptor-related receptor as an extracellular alkali sensor. Cell Metab (2011) 1.00
The venomics of Bothrops alternatus is a pool of acidic proteins with predominant hemorrhagic and coagulopathic activities. J Proteome Res (2010) 0.98
Preliminary investigation of the three-dimensional structure of Salmonella typhimurium uridine phosphorylase in the crystalline state. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.97
Trypanosoma brucei ATG8: structural insights into autophagic-like mechanisms in protozoa. Autophagy (2009) 0.96
Novel boronated chlorin e6-based photosensitizers: synthesis, binding to albumin and antitumour efficacy. Bioorg Med Chem (2008) 0.96
A cytochrome c mutant with high electron transfer and antioxidant activities but devoid of apoptogenic effect. Biochem J (2002) 0.95
Structure of mistletoe lectin I from Viscum album in complex with the phytohormone zeatin. Biochim Biophys Acta (2008) 0.94
Effects of isoprenoid analogues of SDB-ethylenediamine on multidrug resistant tumor cells alone and in combination with chemotherapeutic drugs. J Med Chem (2002) 0.94
The structure of a functional unit from the wall of a gastropod hemocyanin offers a possible mechanism for cooperativity. Biochemistry (2003) 0.93
CHL1 is a selective organizer of the presynaptic machinery chaperoning the SNARE complex. PLoS One (2010) 0.93
Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro. J Struct Biol (2006) 0.92
The 1.2A crystal structure of an E. coli tRNASer)acceptor stem microhelix reveals two magnesium binding sites. Biochem Biophys Res Commun (2009) 0.90
Pyrenemethyl ara-uridine-2'-carbamate: a strong interstrand excimer in the major groove of a DNA duplex. Chembiochem (2003) 0.90
Interaction of three-finger toxins with phospholipid membranes: comparison of S- and P-type cytotoxins. Biochem J (2005) 0.89
In silico design of protein kinase inhibitors: successes and failures. Anticancer Agents Med Chem (2007) 0.88
Multistate organization of transmembrane helical protein dimers governed by the host membrane. J Am Chem Soc (2012) 0.88
X-ray structural studies of the fungal laccase from Cerrena maxima. J Biol Inorg Chem (2006) 0.88
Structure of the functional domain of the major grass-pollen allergen Phlp 5b. Acta Crystallogr D Biol Crystallogr (2002) 0.88
Proteome analysis of snake venom toxins: pharmacological insights. Expert Rev Proteomics (2008) 0.88
Snake venomics of the Siamese Russell's viper (Daboia russelli siamensis) -- relation to pharmacological activities. J Proteomics (2009) 0.87
The crystal structure of an 'All Locked' nucleic acid duplex. Nucleic Acids Res (2010) 0.87
Specific membrane binding of neurotoxin II can facilitate its delivery to acetylcholine receptor. Biophys J (2009) 0.87
Synthesis and cytotoxicity of oligomycin A derivatives modified in the side chain. Bioorg Med Chem (2013) 0.86
Novel photosensitizers trigger rapid death of malignant human cells and rodent tumor transplants via lipid photodamage and membrane permeabilization. PLoS One (2010) 0.86
Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum. J Biol Chem (2003) 0.86
Role of lipid charge in organization of water/lipid bilayer interface: insights via computer simulations. J Phys Chem B (2005) 0.86
Polysaccharide binding sites in hyaluronate lyase--crystal structures of native phage-encoded hyaluronate lyase and its complexes with ascorbic acid and lactose. FEBS J (2009) 0.86
Single-drop optimization of protein crystallization. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.86
Interaction between the elastin peptide VGVAPG and human elastin binding protein. J Biol Chem (2012) 0.85
Monitoring and scoring counter-diffusion protein crystallization experiments in capillaries by in situ dynamic light scattering. PLoS One (2012) 0.85
Structure elucidation of dimeric transmembrane domains of bitopic proteins. Cell Adh Migr (2010) 0.85
PREDDIMER: a web server for prediction of transmembrane helical dimers. Bioinformatics (2013) 0.85
The water channels, new druggable targets to combat cancer cell survival, invasiveness and metastasis. Curr Drug Targets (2007) 0.84
Bacterial eukaryotic type serine-threonine protein kinases: from structural biology to targeted anti-infective drug design. Curr Top Med Chem (2011) 0.84
Lysine as a critical amino acid for IgE binding in Phl p 5b C terminus. Int Arch Allergy Immunol (2006) 0.84
Deciphering fine molecular details of proteins' structure and function with a Protein Surface Topography (PST) method. J Chem Inf Model (2014) 0.84
Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. Biochim Biophys Acta (2011) 0.84
Venom peptide analysis of Vipera ammodytes meridionalis (Viperinae) and Bothrops jararacussu (Crotalinae) demonstrates subfamily-specificity of the peptidome in the family Viperidae. Mol Biosyst (2011) 0.84
Comparative analysis of the venom proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis. J Proteome Res (2008) 0.84
Effect of lipid composition on the "membrane response" induced by a fusion peptide. Biochemistry (2005) 0.84
Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity. J Antibiot (Tokyo) (2009) 0.83
Stem cell transplantation for treatment of liver diseases: from biological foundations to clinical experience (review). Int J Mol Med (2003) 0.83
Modeling of oxidized PTH (oxPTH) and non-oxidized PTH (n-oxPTH) receptor binding and relationship of oxidized to non-oxidized PTH in children with chronic renal failure, adult patients on hemodialysis and kidney transplant recipients. Kidney Blood Press Res (2013) 0.83
Crystal structure of himalayan mistletoe ribosome-inactivating protein reveals the presence of a natural inhibitor and a new functionally active sugar-binding site. J Biol Chem (2005) 0.83
Snake venomic of Crotalus durissus terrificus--correlation with pharmacological activities. J Proteome Res (2010) 0.83
MRSA infections: from classical treatment to suicide drugs. Curr Med Chem (2014) 0.83
Novel boronated derivatives of 5,10,15,20-tetraphenylporphyrin: synthesis and toxicity for drug-resistant tumor cells. Bioorg Med Chem (2005) 0.83
N-terminal amphipathic helix as a trigger of hemolytic activity in antimicrobial peptides: a case study in latarcins. FEBS Lett (2009) 0.83
Reaction of the antitumor antibiotic olivomycin I with aryl diazonium salts. Synthesis, cytotoxic and antiretroviral potency of 5-aryldiazenyl-6-O-deglycosyl derivatives of olivomycin I. Bioorg Med Chem (2009) 0.82
Role of dimerization efficiency of transmembrane domains in activation of fibroblast growth factor receptor 3. J Am Chem Soc (2013) 0.82
Heating Affects Structure, Enterocyte Adsorption and Signalling, As Well as Immunogenicity of the Peanut Allergen Ara h 2. Open Allergy J (2011) 0.82
Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition. Biochem Biophys Res Commun (2004) 0.82
Spatial structure and activity mechanism of a novel spider antimicrobial peptide. Biochemistry (2006) 0.82
Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor. J Struct Biol (2012) 0.82
Complementarity of hydrophobic properties in ATP-protein binding: a new criterion to rank docking solutions. Proteins (2007) 0.82
Structure of the major cytosolic glutathione S-transferase from the parasitic nematode Onchocerca volvulus. J Biol Chem (2005) 0.81
Boronated protohaemins: synthesis and in vivo antitumour efficacy. Org Biomol Chem (2006) 0.81
Specificity of helix packing in transmembrane dimer of the cell death factor BNIP3: a molecular modeling study. Proteins (2007) 0.81
Nontrivial behavior of water in the vicinity and inside lipid bilayers as probed by molecular dynamics simulations. ACS Nano (2013) 0.81
Amino acid sequence and glycosylation of functional unit RtH2-e from Rapana thomasiana (gastropod) hemocyanin. Arch Biochem Biophys (2002) 0.81
Structure and dynamics of cardiotoxins. Curr Protein Pept Sci (2012) 0.81
Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding. Proteins (2006) 0.81
Crystal structure of the disintegrin heterodimer from saw-scaled viper (Echis carinatus) at 1.9 A resolution. Biochemistry (2005) 0.81
Crystallization and preliminary X-ray diffraction analysis of a tRNASer acceptor-stem microhelix. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81
Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution. Acta Crystallogr D Biol Crystallogr (2007) 0.81
3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance. Bioorg Med Chem (2005) 0.81
Snake cytotoxins bind to membranes via interactions with phosphatidylserine head groups of lipids. PLoS One (2011) 0.81
Structural, dynamic, and functional aspects of helix association in membranes: a computational view. Adv Protein Chem Struct Biol (2011) 0.81
Carboranylporphyrins for boron neutron capture therapy of cancer. Curr Med Chem Anticancer Agents (2003) 0.81
Purification, crystallization and preliminary X-ray study of the fungal laccase from Cerrena maxima. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.80
Comparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.80
Adaptation of a membrane-active peptide to heterogeneous environment. II. The role of mosaic nature of the membrane surface. J Phys Chem B (2009) 0.80
Structure of the extracellular glutathione S-transferase OvGST1 from the human pathogenic parasite Onchocerca volvulus. J Mol Biol (2008) 0.80
The structure of a native l-amino acid oxidase, the major component of the Vipera ammodytes ammodytes venomic, reveals dynamic active site and quaternary structure stabilization by divalent ions. Mol Biosyst (2010) 0.80
Dynamic clustering of lipids in hydrated two-component membranes: results of computer modeling and putative biological impact. J Biomol Struct Dyn (2012) 0.80
Three-dimensional model of the honeybee venom allergen Api m 7: structural and functional insights. Mol Biosyst (2010) 0.80
Structure-function relationships in the neurotoxin Vipoxin from the venom of Vipera ammodytes meridionalis. Spectrochim Acta A Mol Biomol Spectrosc (2003) 0.80
Homology modeling of MT1 and MT2 receptors. Eur J Med Chem (2007) 0.80
Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones. Bioorg Med Chem (2009) 0.80
UV-light-induced conversion and aggregation of prion proteins. Free Radic Biol Med (2009) 0.80