Published in J Biol Chem on September 12, 2003
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. BMC Syst Biol (2010) 1.19
Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition. Protein Sci (2005) 0.96
Purification and biochemical characterization of cytosolic glutathione-S-transferase from malarial parasites Plasmodium yoelii. Parasitol Res (2006) 0.80
WISDOM-II: screening against multiple targets implicated in malaria using computational grid infrastructures. Malar J (2009) 0.79
Tetramerization and cooperativity in Plasmodium falciparum glutathione S-transferase are mediated by atypic loop 113-119. J Biol Chem (2009) 0.76
Insights into ligand binding to a glutathione S-transferase from mango: Structure, thermodynamics and kinetics. Biochimie (2017) 0.75
In vivo protein crystallization opens new routes in structural biology. Nat Methods (2012) 2.69
Thiol-based redox metabolism of protozoan parasites. Trends Parasitol (2003) 2.25
Regulation of intracellular glutathione levels in erythrocytes infected with chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. Biochem J (2002) 1.41
Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stages. J Biol Chem (2002) 1.37
Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal. Aging Cell (2005) 1.23
Dimerization of the major birch pollen allergen Bet v 1 is important for its in vivo IgE-cross-linking potential in mice. J Immunol (2005) 1.22
Efficient UV detection of protein crystals enabled by fluorescence excitation at wavelengths longer than 300 nm. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 1.20
Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis. FEBS J (2011) 1.19
Oxidative stress in Caenorhabditis elegans: protective effects of the Omega class glutathione transferase (GSTO-1). FASEB J (2007) 1.12
Analysis of the vitamin B6 biosynthesis pathway in the human malaria parasite Plasmodium falciparum. J Biol Chem (2004) 1.08
The first crystal structure of an RNA racemate. Acta Crystallogr D Biol Crystallogr (2006) 1.08
Tyrosine kinase and cooperative TGFbeta signaling in the reproductive organs of Schistosoma mansoni. Exp Parasitol (2007) 1.05
Fatty acid- and retinoid-binding proteins have distinct binding pockets for the two types of cargo. J Biol Chem (2009) 1.02
Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy. J Biol Chem (2011) 1.01
The spermidine synthase of the malaria parasite Plasmodium falciparum: molecular and biochemical characterisation of the polyamine synthesis enzyme. Mol Biochem Parasitol (2005) 1.01
Structural insights into the catalytic mechanism of sphingomyelinases D and evolutionary relationship to glycerophosphodiester phosphodiesterases. Biochem Biophys Res Commun (2006) 1.00
The ubiquitin-fold modifier 1 (Ufm1) cascade of Caenorhabditis elegans. J Biol Chem (2013) 1.00
3-Aminooxy-1-aminopropane and derivatives have an antiproliferative effect on cultured Plasmodium falciparum by decreasing intracellular polyamine concentrations. Antimicrob Agents Chemother (2005) 1.00
The venomics of Bothrops alternatus is a pool of acidic proteins with predominant hemorrhagic and coagulopathic activities. J Proteome Res (2010) 0.98
Assessing the polyamine metabolism of Plasmodium falciparum as chemotherapeutic target. Mol Biochem Parasitol (2008) 0.98
Glutathione synthetase from Plasmodium falciparum. Biochem J (2002) 0.97
Preliminary investigation of the three-dimensional structure of Salmonella typhimurium uridine phosphorylase in the crystalline state. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.97
Trypanosoma brucei ATG8: structural insights into autophagic-like mechanisms in protozoa. Autophagy (2009) 0.96
The glutathione S-transferase from Plasmodium falciparum. Mol Biochem Parasitol (2002) 0.96
A peroxiredoxin specifically expressed in two types of pharyngeal neurons is required for normal growth and egg production in Caenorhabditis elegans. J Mol Biol (2004) 0.95
Structure of mistletoe lectin I from Viscum album in complex with the phytohormone zeatin. Biochim Biophys Acta (2008) 0.94
Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J Mol Biol (2007) 0.93
The structure of a functional unit from the wall of a gastropod hemocyanin offers a possible mechanism for cooperativity. Biochemistry (2003) 0.93
CHL1 is a selective organizer of the presynaptic machinery chaperoning the SNARE complex. PLoS One (2010) 0.93
The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels. PLoS One (2009) 0.92
Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro. J Struct Biol (2006) 0.92
Functional analysis of the methylmalonyl-CoA epimerase from Caenorhabditis elegans. FEBS J (2005) 0.92
The 1.2A crystal structure of an E. coli tRNASer)acceptor stem microhelix reveals two magnesium binding sites. Biochem Biophys Res Commun (2009) 0.90
Structural metal dependency of the arginase from the human malaria parasite Plasmodium falciparum. Biol Chem (2005) 0.89
Cloning, expression, characterisation and three-dimensional structure determination of Caenorhabditis elegans spermidine synthase. FEBS Lett (2005) 0.89
X-ray structural studies of the fungal laccase from Cerrena maxima. J Biol Inorg Chem (2006) 0.88
Parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase of Plasmodium falciparum modulate catalytic activities and domain interactions. Biochem J (2004) 0.88
Structure of the functional domain of the major grass-pollen allergen Phlp 5b. Acta Crystallogr D Biol Crystallogr (2002) 0.88
A dominant role for extracellular glutathione S-transferase from Onchocerca volvulus is the production of prostaglandin D2. Infect Immun (2003) 0.88
Proteome analysis of snake venom toxins: pharmacological insights. Expert Rev Proteomics (2008) 0.88
The highly abundant protein Ag-lbp55 from Ascaridia galli represents a novel type of lipid-binding proteins. J Biol Chem (2005) 0.87
Snake venomics of the Siamese Russell's viper (Daboia russelli siamensis) -- relation to pharmacological activities. J Proteomics (2009) 0.87
Natural products as a source for treating neglected parasitic diseases. Int J Mol Sci (2013) 0.87
The crystal structure of an 'All Locked' nucleic acid duplex. Nucleic Acids Res (2010) 0.87
The secretory omega-class glutathione transferase OvGST3 from the human pathogenic parasite Onchocerca volvulus. FEBS J (2008) 0.87
The X-ray structure of Salmonella typhimurium uridine nucleoside phosphorylase complexed with 2,2'-anhydrouridine, phosphate and potassium ions at 1.86 A resolution. Acta Crystallogr D Biol Crystallogr (2009) 0.86
gamma-Substituted bis(pivaloyloxymethyl)ester analogues of fosmidomycin and FR900098. Arch Pharm (Weinheim) (2007) 0.86
Polysaccharide binding sites in hyaluronate lyase--crystal structures of native phage-encoded hyaluronate lyase and its complexes with ascorbic acid and lactose. FEBS J (2009) 0.86
Synthesis and antimalarial activity of chain substituted pivaloyloxymethyl ester analogues of Fosmidomycin and FR900098. Bioorg Med Chem (2006) 0.86
Single-drop optimization of protein crystallization. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.86
A novel member of the GCN5-related N-acetyltransferase superfamily from Caenorhabditis elegans preferentially catalyses the N-acetylation of thialysine [S-(2-aminoethyl)-L-cysteine]. Biochem J (2004) 0.86
Conformationally restrained aromatic analogues of fosmidomycin and FR900098. Arch Pharm (Weinheim) (2007) 0.85
Monitoring and scoring counter-diffusion protein crystallization experiments in capillaries by in situ dynamic light scattering. PLoS One (2012) 0.85
Secretion of an acid phosphatase provides a possible mechanism to acquire host nutrients by Plasmodium falciparum. Cell Microbiol (2010) 0.85
Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum. PLoS One (2009) 0.85
Identification of major antigenic peptide of filarial glutathione-S-transferase. Vaccine (2010) 0.85
Novel properties of malarial S-adenosylmethionine decarboxylase as revealed by structural modelling. J Mol Graph Model (2005) 0.85
Cooperativity and pseudo-cooperativity in the glutathione S-transferase from Plasmodium falciparum. J Biol Chem (2005) 0.85
Comparative analysis of the venom proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis. J Proteome Res (2008) 0.84
Lysine as a critical amino acid for IgE binding in Phl p 5b C terminus. Int Arch Allergy Immunol (2006) 0.84
Venom peptide analysis of Vipera ammodytes meridionalis (Viperinae) and Bothrops jararacussu (Crotalinae) demonstrates subfamily-specificity of the peptidome in the family Viperidae. Mol Biosyst (2011) 0.84
Brugia malayi and Wuchereria bancrofti: gene comparison and recombinant expression of pi-class related glutathione S-transferases. Exp Parasitol (2003) 0.83
Snake venomic of Crotalus durissus terrificus--correlation with pharmacological activities. J Proteome Res (2010) 0.83
Crystal structure of himalayan mistletoe ribosome-inactivating protein reveals the presence of a natural inhibitor and a new functionally active sugar-binding site. J Biol Chem (2005) 0.83
An aspartate aminotransferase of Wolbachia endobacteria from Onchocerca volvulus is recognized by IgG1 antibodies from residents of endemic areas. Parasitol Res (2003) 0.83
Modeling of oxidized PTH (oxPTH) and non-oxidized PTH (n-oxPTH) receptor binding and relationship of oxidized to non-oxidized PTH in children with chronic renal failure, adult patients on hemodialysis and kidney transplant recipients. Kidney Blood Press Res (2013) 0.83
MRSA infections: from classical treatment to suicide drugs. Curr Med Chem (2014) 0.83
The glutathione reductase GSR-1 determines stress tolerance and longevity in Caenorhabditis elegans. PLoS One (2013) 0.82
Caenorhabditis elegans P5B-type ATPase CATP-5 operates in polyamine transport and is crucial for norspermidine-mediated suppression of RNA interference. FASEB J (2009) 0.82
Heating Affects Structure, Enterocyte Adsorption and Signalling, As Well as Immunogenicity of the Peanut Allergen Ara h 2. Open Allergy J (2011) 0.82
Structural insights into serine protease inhibition by a marine invertebrate BPTI Kunitz-type inhibitor. J Struct Biol (2012) 0.82
Asp49 phospholipase A(2)-elaidoylamide complex: a new mode of inhibition. Biochem Biophys Res Commun (2004) 0.82
Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution. Acta Crystallogr D Biol Crystallogr (2007) 0.81
Crystallization and preliminary X-ray diffraction analysis of a tRNASer acceptor-stem microhelix. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81
Vitamin B1 de novo synthesis in the human malaria parasite Plasmodium falciparum depends on external provision of 4-amino-5-hydroxymethyl-2-methylpyrimidine. Biol Chem (2006) 0.81
Crystal structure of the disintegrin heterodimer from saw-scaled viper (Echis carinatus) at 1.9 A resolution. Biochemistry (2005) 0.81
Characterization of a secreted macrophage migration inhibitory factor homologue of the parasitic nematode Strongyloides acting at the parasite-host cell interface. Microbes Infect (2011) 0.81
Amino acid sequence and glycosylation of functional unit RtH2-e from Rapana thomasiana (gastropod) hemocyanin. Arch Biochem Biophys (2002) 0.81
Structure of the major cytosolic glutathione S-transferase from the parasitic nematode Onchocerca volvulus. J Biol Chem (2005) 0.81
Arylmethyl substituted derivatives of Fosmidomycin: synthesis and antimalarial activity. Eur J Med Chem (2006) 0.81
The antioxidative effect of de novo generated vitamin B6 in Plasmodium falciparum validated by protein interference. Biochem J (2012) 0.81
Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding. Proteins (2006) 0.81
Structure of the extracellular glutathione S-transferase OvGST1 from the human pathogenic parasite Onchocerca volvulus. J Mol Biol (2008) 0.80
Purification, crystallization and preliminary X-ray study of the fungal laccase from Cerrena maxima. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.80
Comparative crystallization and preliminary X-ray diffraction studies of locked nucleic acid and RNA stems of a tenascin C-binding aptamer. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.80
Structure-function relationships in the neurotoxin Vipoxin from the venom of Vipera ammodytes meridionalis. Spectrochim Acta A Mol Biomol Spectrosc (2003) 0.80
Three-dimensional model of the honeybee venom allergen Api m 7: structural and functional insights. Mol Biosyst (2010) 0.80
UV-light-induced conversion and aggregation of prion proteins. Free Radic Biol Med (2009) 0.80