Published in Obesity (Silver Spring) on January 07, 2010
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Mispairing C57BL/6 substrains of genetically engineered mice and wild-type controls can lead to confounding results as it did in studies of JNK2 in acetaminophen and concanavalin A liver injury. Chem Res Toxicol (2011) 1.18
Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle. J Biol Chem (2013) 1.15
Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet. ISME J (2014) 1.13
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Characterization of the heterozygous glucokinase knockout mouse as a translational disease model for glucose control in type 2 diabetes. Br J Pharmacol (2014) 0.80
Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine. J Hepatol (2014) 0.80
Assessing interactions between Ghsr and Mc3r reveals a role for AgRP in the expression of food anticipatory activity in male mice. Endocrinology (2014) 0.80
Modulating Molecular Chaperones Improves Mitochondrial Bioenergetics and Decreases the Inflammatory Transcriptome in Diabetic Sensory Neurons. ACS Chem Neurosci (2015) 0.79
Parallel universes of Black Six biology. Biol Direct (2014) 0.79
Vitamin E and vitamin C do not reduce insulin sensitivity but inhibit mitochondrial protein expression in exercising obese rats. Appl Physiol Nutr Metab (2014) 0.79
Comparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts. Transgenic Res (2012) 0.79
Impact of a novel homozygous mutation in nicotinamide nucleotide transhydrogenase on mitochondrial DNA integrity in a case of familial glucocorticoid deficiency. BBA Clin (2015) 0.77
The Contribution of Nicotinamide Nucleotide Transhydrogenase to Peroxide Detoxification Is Dependent on the Respiratory State and Counterbalanced by Other Sources of NADPH in Liver Mitochondria. J Biol Chem (2016) 0.76
A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice. Diabetes (2016) 0.76
Sex-related differences in small intestinal transit and serotonin dynamics in high-fat-diet-induced obesity in mice. Exp Physiol (2015) 0.75
High fat feeding unmasks variable insulin responses in male C57BL/6 mouse substrains. J Endocrinol (2017) 0.75
Methodological considerations when studying the skeletal response to glucose intolerance using the diet-induced obesity model. Bonekey Rep (2016) 0.75
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Differences in bone structure and unloading-induced bone loss between C57BL/6N and C57BL/6J mice. Mamm Genome (2017) 0.75
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A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice. Diabetologia (2005) 2.37
Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion. Cell Metab (2006) 2.21
Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice. Diabetes (2006) 2.17
The genetic landscape of type 2 diabetes in mice. Endocr Rev (2006) 1.88
Genetic analysis of glucose tolerance in inbred mouse strains. Evidence for polygenic control. Diabetes (1988) 1.56
Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet. J Endocrinol (2005) 1.51
Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes. Diabetologia (2007) 1.23
Alcohol trait and transcriptional genomic analysis of C57BL/6 substrains. Genes Brain Behav (2008) 1.17
How pure are inbred strains of mice? Immunol Today (1982) 1.05
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature (2004) 5.85
An efficient SNP system for mouse genome scanning and elucidating strain relationships. Genome Res (2004) 3.96
Mouse models of diabetic nephropathy. J Am Soc Nephrol (2009) 3.74
Noninvasive treatment of malignant bone tumors using high-intensity focused ultrasound. Cancer (2010) 2.43
Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone. J Lipid Res (2002) 2.30
Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alström syndrome. Hum Mutat (2007) 2.20
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Cdcs1, a major colitogenic locus in mice, regulates innate and adaptive immune response to enteric bacterial antigens. Gastroenterology (2005) 1.81
Resistance of C57BL/6 mice to amoebiasis is mediated by nonhemopoietic cells but requires hemopoietic IL-10 production. J Immunol (2006) 1.77
Molecular networks for the study of TCM pharmacology. Brief Bioinform (2009) 1.53
The response of C57BL/6J and BALB/cJ mice to increased housing density. J Am Assoc Lab Anim Sci (2009) 1.52
Baicalein selectively induces apoptosis in activated lymphocytes and ameliorates concanavalin a-induced hepatitis in mice. PLoS One (2013) 1.48
Chemical fingerprinting of Liuwei Dihuang Pill and simultaneous determination of its major bioactive constituents by HPLC coupled with multiple detections of DAD, ELSD and ESI-MS. J Pharm Biomed Anal (2008) 1.45
Characterization of hand, foot, and mouth disease in China between 2008 and 2009. Biomed Environ Sci (2011) 1.41
Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice. Genetics (2002) 1.29
Repeated administrations of carbon nanotubes in male mice cause reversible testis damage without affecting fertility. Nat Nanotechnol (2010) 1.23
Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes. Am J Physiol Endocrinol Metab (2007) 1.23
Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice. Diabetes (2002) 1.22
Refined histopathologic scoring system improves power to detect colitis QTL in mice. Mamm Genome (2004) 1.20
New mouse model to study islet transplantation in insulin-dependent diabetes mellitus. Transplantation (2002) 1.17
Genome-wide association mapping of quantitative traits in outbred mice. G3 (Bethesda) (2012) 1.17
Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene. J Lipid Res (2009) 1.16
Caspase-1 is not required for type 1 diabetes in the NOD mouse. Diabetes (2004) 1.16
Nasopharyngeal carcinoma risk by histologic type in central China: impact of smoking, alcohol and family history. Int J Cancer (2010) 1.13
CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins. J Immunol (2005) 1.12
Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes. Diabetes (2004) 1.09
Host DNA repair proteins in response to Pseudomonas aeruginosa in lung epithelial cells and in mice. Infect Immun (2010) 1.09
Therapeutic effects of astragaloside IV on myocardial injuries: multi-target identification and network analysis. PLoS One (2012) 1.07
Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion. J Immunol (2006) 1.06
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism. Vascul Pharmacol (2006) 1.04
Protective and antifecundity effects of Sm-p80-based DNA vaccine formulation against Schistosoma mansoni in a nonhuman primate model. Vaccine (2009) 1.04
Mechanisms underlying resistance of pancreatic islets from ALR/Lt mice to cytokine-induced destruction. J Immunol (2005) 1.04
A combined HPLC-PDA and HPLC-MS method for quantitative and qualitative analysis of 10 major constituents in the traditional Chinese medicine Zuo Gui Wan. J Pharm Biomed Anal (2009) 1.03
Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells. J Biol Chem (2005) 1.03
Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. Proc Natl Acad Sci U S A (2004) 1.03
A new cultivation method for microbial oil production: cell pelletization and lipid accumulation by Mucor circinelloides. Biotechnol Biofuels (2011) 1.02
FNDC3A is required for adhesion between spermatids and Sertoli cells. Dev Biol (2006) 1.02
Regional differences in HIV prevalence among drug users in China: potential for future spread of HIV? BMC Infect Dis (2008) 1.02
Prediction of 24-hour-average PM(2.5) concentrations using a hidden Markov model with different emission distributions in Northern California. Sci Total Environ (2012) 1.01
Genetic and environmental context determines the course of colitis developing in IL-10-deficient mice. Inflamm Bowel Dis (2002) 1.01
Mucoepidermoid carcinoma of the lung: common findings and unusual appearances on CT. Clin Imaging (2012) 1.00
Prime-boost and recombinant protein vaccination strategies using Sm-p80 protects against Schistosoma mansoni infection in the mouse model to levels previously attainable only by the irradiated cercarial vaccine. Parasitol Res (2009) 1.00
P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide. J Immunol (2005) 1.00
Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. J Pharm Biomed Anal (2009) 0.98
Computed tomographic and pathological findings of dermatofibrosarcoma protuberans. J Comput Assist Tomogr (2012) 0.98
Expression of hepatitis B virus proteins in transgenic mice alters lipid metabolism and induces oxidative stress in the liver. J Hepatol (2007) 0.97
TTLL10 is a protein polyglycylase that can modify nucleosome assembly protein 1. FEBS Lett (2008) 0.97
The serum metabolomic study of intervention effects of the traditional Chinese medicine Shexiang Baoxin Pill and a multi-component medicine polypill in the treatment of myocardial infarction in rats. Mol Biosyst (2012) 0.95
Therapeutic effects and prognostic factors in high-intensity focused ultrasound combined with chemoembolisation for larger hepatocellular carcinoma. Eur J Cancer (2010) 0.95
Clinical value of whole-body F-18 fluorodeoxyglucose positron emission tomography/computed tomography in patients with carcinoma of unknown primary. J Med Imaging Radiat Oncol (2012) 0.95
A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein. FEBS Lett (2006) 0.94
Mapping of genetic modifiers of Nr2e3 rd7/rd7 that suppress retinal degeneration and restore blue cone cells to normal quantity. Mamm Genome (2008) 0.94
Cdcs1 a major colitis susceptibility locus in mice; subcongenic analysis reveals genetic complexity. Inflamm Bowel Dis (2010) 0.93
Type 2 diabetes mouse model TallyHo carries an obesity gene on chromosome 6 that exaggerates dietary obesity. Physiol Genomics (2005) 0.92
Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress. Immunogenetics (2003) 0.92
Rapid-resolution liquid chromatography TOF-MS for urine metabolomic analysis of collagen-induced arthritis in rats and its applications. J Ethnopharmacol (2012) 0.92
Thiolated chitosan/DNA nanocomplexes exhibit enhanced and sustained gene delivery. Pharm Res (2006) 0.92
Imaging features and pathologic characteristics of ovarian thecoma. J Comput Assist Tomogr (2012) 0.92
CD38 is required for the peripheral survival of immunotolerogenic CD4+ invariant NK T cells in nonobese diabetic mice. J Immunol (2006) 0.91
Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry. J Pharm Biomed Anal (2009) 0.91
"Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells. Mamm Genome (2005) 0.90
Berberine induces dendritic cell apoptosis and has therapeutic potential for rheumatoid arthritis. Arthritis Rheum (2011) 0.89
Adipokine and insulin profiles distinguish diabetogenic and non-diabetogenic obesities in mice. Obesity (Silver Spring) (2007) 0.89
The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. J Ethnopharmacol (2011) 0.89
Chemical constituents of the stems of Celastrus rugosus. Arch Pharm Res (2013) 0.89
Hyperbaric oxygen preconditioning alleviates myocardial ischemic injury in rats. Exp Biol Med (Maywood) (2008) 0.89
Protective effects of Sm-p80 in the presence of resiquimod as an adjuvant against challenge infection with Schistosoma mansoni in mice. Int J Infect Dis (2010) 0.89
Huang-Lian-Jie-Du-Tang exerts anti-inflammatory effects in rats through inhibition of nitric oxide production and eicosanoid biosynthesis via the lipoxygenase pathway. J Pharm Pharmacol (2009) 0.89
Quantitative trait loci for baseline erythroid traits. Mamm Genome (2006) 0.88
Computed tomography appearance of inflammatory myofibroblastic tumor in the mediastinum. J Comput Assist Tomogr (2012) 0.88
Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice. J Immunol (2011) 0.88
Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes. Diabetes (2005) 0.88
Potential biomarkers in the urine of myocardial infarction rats: a metabolomic method and its application. Mol Biosyst (2010) 0.88
A meta-analysis of 2-year effect after surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity and diabetes mellitus. Obes Surg (2014) 0.88
Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene. Genet Vaccines Ther (2007) 0.88
NOD x 129.H2(g7) backcross delineates 129S1/SvImJ-derived genomic regions modulating type 1 diabetes development in mice. Diabetes (2009) 0.88
Flavonoids from Daphne giraldii Nitsche. Nat Prod Res (2008) 0.88
Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice. Free Radic Biol Med (2002) 0.88
Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume. Mamm Genome (2005) 0.88
Biomarkers in the early period of acute myocardial infarction in rat serum and protective effects of Shexiang Baoxin Pill using a metabolomic method. J Ethnopharmacol (2011) 0.87
PD-1 expression on peripheral CD8+ TEM/TEMRA subsets closely correlated with HCV viral load in chronic hepatitis C patients. Virol J (2010) 0.87
Metabonomic characterization of aging and investigation on the anti-aging effects of total flavones of Epimedium. Mol Biosyst (2009) 0.87
Engineered fusion hybrid vaccine of IL-4 gene-modified myeloma and relative mature dendritic cells enhances antitumor immunity. Leuk Res (2002) 0.87
mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic β-cell. Diabetes (2010) 0.86
Protective effects of grape seed proanthocyanidin extracts on cerebral cortex of streptozotocin-induced diabetic rats through modulating AGEs/RAGE/NF-kappaB pathway. J Nutr Sci Vitaminol (Tokyo) (2010) 0.86
Drug resistance and HCV coinfection in former blood donors infected with HIV type 1 in China. AIDS Res Hum Retroviruses (2011) 0.86
Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice. J Immunol (2008) 0.86
Major histocompatibility complex-linked diabetes susceptibility in NOD/Lt mice: subcongenic analysis localizes a component of Idd16 at the H2-D end of the diabetogenic H2(g7) complex. Diabetes (2005) 0.86
Flow cytometric and immunoblot assays for cell surface ADP-ribosylation using a monoclonal antibody specific for ethenoadenosine. Anal Biochem (2003) 0.86
Metabonomic study on ageing: NMR-based investigation into rat urinary metabolites and the effect of the total flavone of Epimedium. Mol Biosyst (2008) 0.86
LC-MS/MS method for the simultaneous determination of icariin and its major metabolites in rat plasma. J Pharm Biomed Anal (2007) 0.85
Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids. Cancer Cell Int (2007) 0.85
Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis. Diabetes (2005) 0.85